Nea ɛsɛ sɛ wuhu fa androgens ho!

So woate androgens ho asɛm pɛn? Ebia yiw, ebia ɛnte saa. Nanso wɔyɛ hormone kuw bi a ɛwɔ yɛn nipadua nyinaa mu na ɛho hia yiye ma yɛn nna mu nkɔso ne yɛn akwahosan. Saa androgens yi te sɛ asomfo nkumaa a wɔreyɛ adwuma wɔ akyi wɔ yɛn nipadua mu. Ɛnnɛ, yɛbɛka wɔn ho asɛm wɔ ɔkwan a ɛnyɛ den so a wubetumi ate ase.

Sɛ yɛbɛka no tiawa a, androgens yɛ nna mu ahoɔdennuru bi. Ɛno na ɛma yɛn ho akokwaw, na ɛboa ma yɛn awo nhyehyɛe no akwahosan ne yɛn nipadua nyin nso. Ebia wubesusuw sɛ mmarima nkutoo na wɔwɔ bi. Nanso nokwarem no, yɛn nyinaa, sɛ́ yɛyɛ mmarima anaa mmea no, wɔ androgens wɔ yɛn nipadua mu. Nanso, wofi awosu mu na wɔyɛ no dodow a ɛkɔ soro wɔ mmarima mu. Testosterone a yɛn mu pii ate ho asɛm no nso yɛ androgen titiriw.

Afei ebia woresusuw baabi a saa hormone ahorow yi fi ho. Androgens no fi mmadwoa a ɛwɔ mmarima awo nhyehyɛe mu ne mmadwoa a ɛwɔ mmea awo nhyehyɛe mu no titiriw. Nea ɛka ho no, adrenal glands a ɛwɔ yɛn asaabo atifi no nso na ɛyɛ saa hormone ahorow yi. Androgens nyɛ nea ɛwɔ hɔ ara kwa. Wɔyɛ ɔsom kɛse wɔ yɛn nna mu nkɔso ne yɛn akwahosan nyinaa a yɛbɛkɔ so akura mu no mu. Wɔn dodow betumi asesa da mũ no nyinaa. Afei nso, saa hormone dodow yi sesa wɔ yɛn asetra mu mmere ahorow mu, te sɛ bere a yɛadu mpanyin afe so ne bere a yɛagyae brayɛ no.

Androgen ahorow bɛn na ɛwɔ hɔ?

Sɛnea yɛadi kan aka no, testosterone ne androgen titiriw a yɛn nyinaa wɔ. Androgen afoforo pii boa ma wɔyɛ hormone afoforo. Sɛ nhwɛso no, androgen ahorow a edidi so yi boa ma wɔyɛ testosterone ne estrogen:

• Androstenedione a wɔde yɛ aduru
• Dehydroepiandrosterone (DHEA) a ɛma mogya tu .
• DHEA sulfate (DHEA sulfate - DHEAS) a ɛyɛ adwuma wɔ ɔkwan a ɛyɛ mmerɛw so.

Androgen foforo ne dihydrotestosterone (DHT) . Bere a worenyin no, wo nipadua dan wo testosterone bɛyɛ 10% ma ɛbɛyɛ DHT da biara. Nea ɛka ho no, androgen ahorow afoforo pii ne nnuru dodow bi a ɛfa androgen ho wɔ hɔ. Ɔkwan a yɛn nipadua fa so de saa hormone ahorow yi di dwuma no yɛ nea ɛyɛ den yiye, te sɛ afiri kɛse bi.

Ɔsom bɛn na androgens de ma yɛn nipadua?

Androgens a ɛwɔ yɛn nyinaa mu, ɛmfa ho sɛ ɔyɛ ɔbarima anaa ɔbea, boa wɔ saa nneɛma yi mu:

• Nnompe a ɛyɛ den: Eyinom ho hia na ama yɛn nnompe akɔ so ayɛ den.
• Ntini a nyin: Eyinom nso ho hia na ama ntini anyin.
• Mmabunbere: Eyinom ne nsakrae atitiriw a ɛba fi mmofraase kosi mpanyin afe so.
• Mogya mu nkwammoaa kɔkɔɔ a wɔyɛ (Erythropoiesis): Ɛsan nso boa ma mogya mu nkwammoaa kɔkɔɔ ba yɛn nipadua mu.
• Ɔbarima ne ɔbea nna ho akɔnnɔ ne ne dwumadi: Eyinom ka nna ho nkate ne nna mu dwumadi a ɛkɔ so.

Dɛn pɔtee na ɛto mmarima a wɔwɔ androgens?

Androgens a ɛwɔ ɔbarima nipadua mu no boa ma:

• Ɛnne a emu dɔ (vocal cord lengthening): Ɛnne a ɛyɛ brɛoo a na wowɔ bere a na woyɛ abofra no sesa, na ɔbarima nne ba esiane eyi nti. Fa no sɛ, w'adamfo no ba sesa ne nne mpofirim, na wususuw sɛ, "Onua, ɔyɛ abarimaa kɛse mprempren," ɛnte saa? Nea enti a ɛte saa ne androgens.
• Twe a wobɛware: Saa nkwaadɔm yi nso ka obi tenten.
• Nwi a enyin wɔ anim, ti nhwi, koko, asen, ne ɔbarima ne ɔbea nna mu mmeae: Nneɛma te sɛ abɔgyesɛ nyin ne koko mu nhwi nyin.
• Nkwaboaa nyin: Eyinom ho hia na ama wɔanya mmadwoa a ehia na ama wɔatumi ayɛ abofra.

Saa nipadua mu su ahorow yi dodow no ara fi ase wɔ mmerantebere ne mmabaabere mu. Nanso ɛsono sɛnea testosterone yɛ wɔ asetra mu mmere ahorow mu. Bere a wobɛyɛ ɔpanyin no, wo testosterone dodow so tew fi awosu mu bere a worenyin no.

Ɔkwan bɛn so na androgens ka mmea?

Wɔ mmea fam no, nipadua mu nnuru afoforo dan androgen testosterone ma ɛdan estradiol, estrogen hormone bi . Saa estradiol yi:

• Nna mu su a ɛto so abien a ɛba wɔ mmerantebere ne mmabaabere mu: sɛ nhwɛso no, nufu nyin ne asen a ɛtrɛw.
• Ɛhwɛ brayɛ so: Ɛboa ma ɔsram biara brayɛ kɔ so tra hɔ.
• Aids conception and pregnancy: Eyinom ho hia na ama wɔanyinsɛn abofra na wɔatumi aso nyinsɛn yiye.
• Ɛma nnompe a ɛyera so tew - Nnompe mu yare: Ɛboa ma asiane a ɛwɔ hɔ sɛ nnompe mu yare , a ɛyɛ tebea a ɛba bere a nnompe abubu, titiriw bere a yɛrenyin no so tew.

Estradiol dodow a ɛwɔ wo nipadua mu no sesa wɔ w’asetra mu mmere ahorow mu. Bere a woagyae brayɛ, a ɛyɛ bere a wo bra gyae ɔsram biara no, wo nipadua no ntumi nyɛ estradiol pii saa.

Ɔhaw ahorow bɛn na mmarima wɔ wɔ androgens ho?

Tebea bi a wɔfrɛ no male hypogonadism, a ɛyɛ androgen dodow a ɛso tew, anaa testosterone dodow a ɛso tew, na ɛtaa ka mmarima. Eyi betumi ama nna ho akɔnnɔ so atew na wanya ɔbarima ne ɔbea nna mu ɔhaw.Nsɛnkyerɛnne te sɛ: Sɛ wowɔ biribi te sɛ eyi a, ɛho hia paa sɛ wo ne oduruyɛfo kasa a woremfa nsie wo ho na worenhaw wo ho.

Wɔ nnipa binom fam no, androgens betumi ama prostate kokoram aba. Wɔ tebea horow a ɛtete saa mu no, ebia ebehia sɛ wonom nnuru na ama nipadua no ayɛ androgens a efi awosu mu no so. Nnuruyɛfo frɛ saa ayaresa yi Androgen Deprivation Therapy (ADT) .

Androgens – titiriw DHT (Dihydrotestosterone) – nso ne mmarima-pattern baldness , tebea a wɔfrɛ no androgenic alopecia , wɔ abusuabɔ. Saa hormone ahorow yi nso boa ma ti nhwi a nnipa pii frɛ no ‘waxiness’ no ba.

Ɔhaw bɛn na mmea wɔ wɔ androgens ho?

Ɔhaw ahorow a ɛfa androgen dodow a ɛkɔ soro (hyperandrogenism) ho titiriw na ɛka mmea . Nea ɛde eyi ba titiriw ne tebea bi a wɔfrɛ no Polycystic Ovary Syndrome (PCOS) . Saa PCOS yi yɛ biribi a wohu wɔ mmea pii mu nnansa yi. So wunim sɛ ɛtɔ mmere bi a PCOS betumi ama nyinsɛn akyɛ? Ɛntaa mma sɛ androgen dodow nso betumi akɔ soro esiane akisikuru a ɛwɔ adrenal glands anaa ovaries mu nti.

Nnipa a wɔwɔ PCOS, anaa wɔn a wɔwɔ androgens pii no betumi anya sɛnkyerɛnne ahorow te sɛ:

• Akisikuru: Akisikuru pue wɔ anim, moma so, ne akyi. Ɛtɔ mmere bi a, saa akisikuru yi betumi ayɛ ahometew kɛse.
• Amenorrhea anaa brayɛ a ɛnkɔ so daa: Brayɛ a ɛnkɔ bere a ɛfata mu, anaasɛ ɛkyɛ asram pii.
• Nwi a enyin dodo (hirsutism): Nwi a enyin a wɔmpɛ wɔ abɔgyesɛ, moma so, ne yafunu so, te sɛ abɔgyesɛ. Eyi betumi aka mmea pii nso wɔ adwene mu.
• Mogya mmoroso ne srade a ɛkɔ soro.
• Ɛyɛ den sɛ wobɛwo mma (Infertility).
• Kɛse mmoroso: Sɛ obi mu duru boro so.

Androgens – titiriw DHT (Dihydrotestosterone) – nso betumi aka mmea ti nhwi a ɛyɛ mmerɛw . Mmea binom nso ti nhwi a ɛyɛ mmerɛw na wɔn ti nhwi yɛ mmerɛw, ɛnte saa? Saa hormone yi nya ɛno nso so nkɛntɛnso.

Ɔhaw ahorow bɛn na ebetumi aba esiane androgen dodow a ɛwɔ mmofra nkumaa mu nti?

Ɔhaw ahorow a ɛfa androgen dodow a ɛwɔ mmofra mu ho no betumi ama wɔakyɛ wɔ mmerantebere ne mmabaabere mu anaasɛ wɔadu mpanyin afe so ntɛm.Yiw, ebetumi aba. Nneɛma pii betumi ama eyinom mu biara aba. Sɛ nhwɛso no, mmofra binom da wɔn mmabunbere ho sɛnkyerɛnne adi ntɛm sen afoforo. Na mmofra binom ntumi nkɔ mmerantebere ne mmabaabere mu mpo bere a wɔadu mpanyin afe so no. Eyinom abien nyinaa yɛ tebea horow a ehia sɛ wɔde wɔn kɔ ayaresabea.

Androgen dodow nso ne tebea horow a wɔfrɛ no nna mu nkɔso mu ɔhaw ahorow wɔ abusuabɔ . Eyi kyerɛ kuw bi a tebea horow bɛyɛ 60 a obi wɔ ɔbarima ne ɔbea su nyinaa wom. Eyinom yɛ tebea horow a emu yɛ den kakra, enti ehia sɛ nnuruyɛfo hwɛ so titiriw.

Ɔkwan bɛn so na nnuruyɛfo susuw androgen dodow?

Sɛnea ɛbɛyɛ na nnuruyɛfo ahwɛ sɛ ebia androgen dodow a ɛdɔɔso wɔ ɔbea bi mu no, wɔtaa de nhwehwɛmu bi a wɔfrɛ no Free Androgen Index (FAI) . Wɔnam mogya a wɔfa na wɔsusuw nea edidi so yi so na ɛsusuw FAI no:

• Testosterone a ɛwɔ nipadua no mu nyinaa
• Testosterone a wɔde ma kwa
• Globulin a ɛkyekyere ɔbarima ne ɔbea nna mu nkwaadɔm (SHBG) .

SHBG yɛ protein a ɛde androgens (te sɛ testosterone ne DHT) ne estrogen kɔ mogya no mu. Wo duruyɛfo no bebu wo androgen dodow denam wo testosterone dodow nyinaa a ɔde bɛtoto SHBG ho no so.

Wɔ mmarima fam no, nnuruyɛfo taa hyɛ sɛ wɔnyɛ testosterone mogya mu nhwehwɛmu de hwɛ sɛ testosterone dodow sua anaa.

Nanso kae sɛ, saa mogya mu nhwehwɛmu ahorow yi nkutoo ntumi nkyerɛ wo biribiara. Wo duruyɛfo begyina nneɛma pii so asi gyinae, a nea ɛka ho ne wo yare no ho sɛnkyerɛnne ne aduruyɛ mu nhwehwɛmu.

Enti, nkrasɛm bɛn na ɛsɛ sɛ yɛde fi eyinom nyinaa mu kɔ fie?

Androgens ho hia ma awo akwahosan ne yɛn nyinaa yiyedi nyinaa, mmea, mmarima, mmofra ne mpanyin. Nanso sɛ eyinom betumi ayɛ adwuma yiye a, ɛsɛ sɛ wɔkari pɛ yiye . Te sɛ nsenia no, sɛ emu yɛ duru dodo wɔ ɔfã biako a, ɔhaw bi wɔ hɔ. Kakraa dodo, ɔhaw bi wɔ hɔ; dodo, ɔhaw bi wɔ hɔ.

Sɛ nhwɛso no, sɛ wowɔ sɛnkyerɛnne ahorow a ɛkyerɛ sɛ androgen dodow a ɛba fam anaasɛ ɛkɔ soro, sɛnea yɛadi kan aka no, nna ho akɔnnɔ a wunni, ɛyɛ den sɛ wobɛma mmarima asɔre, bra a ɛnkɔ so daa, wo ti nhwi nyin dodo, akisikuru wɔ mmea mu, anaasɛ abofra bi a ɔkyɛ anaasɛ onyin ntɛm a, hwɛ hu sɛ wobɛkɔ oduruyɛfo nkyɛn akɔhwehwɛ afotu . Afei oduruyɛfo no betumi ayɛ nhwehwɛmu a ɛho hia na wahu nea ɛde wo sɛnkyerɛnne ahorow no ba ankasa. Mma ɛnhaw wo, mpɛn pii no, ayaresa pa wɔ hɔ ma eyi.

Kae sɛ wunim wo nipadua yiye. Sɛ wuhu nsakrae anaa nneɛma bi a ɛnteɛ a, nyansa wom sɛ wobɛhwehwɛ aduruyɛ mu afotu mmom sen sɛ wubebu w’ani agu so.

` Androgens, Testosterone, Hormones, Awo Akwahosan, PCOS, Mmarima Akwahosan, Mmea Akwahosan