Ɛtɔ mmere bi a obi a ɔwɔ Parkinson yare no nya ‘off’ bere a nipadua no yɛ nea nkwa nnim mpofirim, ne akwaa hwere ahoɔden, na entumi nkɔ baabiara yiye. Wɔ saa mmere yi mu no, wɔte nka sɛ wontumi nyɛ hwee na wontumi nyɛ da biara da nnwuma mpo. Enti, ɛnnɛ yɛreka aduru titiriw bi a ɛboa ma wodi ‘off’ bere a ɛte saa a ɛba mpofirim no so ntɛmntɛm ho asɛm.
Dɛn ne aduru yi a wɔfrɛ no Apomorphine?
Sɛ yɛbɛka no tiawa a, Apomorphine yɛ aduru a wɔde sa Parkinson yare no fã a ‘wɔagyae’, a ɛyɛ kankyee a ɛyɛ den mpofirim. Ɛba sɛ ade a ɛyɛ tratraa a ɛpete wɔ tɛkrɛma no ase. KYNMOBI yɛ aduru yi din a wonim no yiye.
Fa no sɛ, nnuru titiriw bi a wɔfrɛ no dopamine wɔ yɛn amemene mu. Eyi na ɛboa yɛn ma yedi yɛn nipadua no kankyee ne ne nhyehyɛe so. Dopamine yi dodow a ɛwɔ obi a ɔwɔ Parkinson yare no amemene mu no so tew. Apomorphine ma dopamine dodow a ɛwɔ amemene no mu no yɛ kɛse, na ɛtew sɛnkyerɛnne ahorow te sɛ nea ɛyɛ den, ne ho popo, ne nea ɛkɔ brɛoo no so ntɛmntɛm.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na wode saa aduru yi adi dwuma
Ɛho hia paa sɛ wo duruyɛfo no hu w’akwahosan tebea no yiye ansa na wama wo saa aduru yi. Enti, sɛ wowɔ tebea horow a edidi so yi mu biara a, hwɛ hu sɛ wobɛka ho asɛm akyerɛ wo duruyɛfo.
| Hwɛ sɛ wowɔ saa tebea horow yi anaa |
|---|
| Sɛ woda mpofirim bere a woreyɛ da biara da nnwuma (sɛ nhwɛso no, worekasa, woredidi) a . |
| Sɛ ɛyɛ den ma wo sɛ wubedi wo ntini ahorow so a |
| Sɛ wowɔ komayare biara, wo koma bɔ a ɛnteɛ, anaasɛ ɛsakra sɛnea wo nnyigyei yɛ no a |
| Sɛ wo mogya mmoroso a ɛba fam a |
| Sɛ wowɔ asaabo anaa mmerɛbo mu yare a |
| Sɛ wowɔ ɔhome mu haw te sɛ ahurututu mu yare anaa ayamtu a |
| Sɛ woanya akisikuru a |
| Sɛ wowɔ adwenemyare biara a |
| Sɛ wowɔ nna mu ahomegye a |
| Sɛ woyɛ obi a ɔnom nsa daa a |
| Sɛ wo ho yɛ wo hyew wɔ apomorphine, sulfites, anaa aduru foforo biara, aduan, anaa kɔla ho a. |
| Sɛ woanyinsɛn anaasɛ wowɔ anidaso sɛ wubenyinsɛn a |
| Sɛ woyɛ ɛna a ɔma nufu a |
Ɔkwan bɛn so ankasa na mede saa aduru yi di dwuma?
Eyi yɛ mmerɛw yiye sɛ wode bedi dwuma, nanso ɛsɛ sɛ wudi akwankyerɛ no akyi pɛpɛɛpɛ.
1. Fa saa aduru yi di dwuma bere a ‘Off’ tebea bi afi ase nkutoo .
2. Ɛsɛ sɛ wo nsa ho yɛ hyew koraa ansa na wode aduru no adi dwuma.
3. Bubu foil kotoku a wɔatoto mu a aduru no wom no na fa ahwɛyiye yi film a ɛrepete no.
4. Fa saa ntini no to wo tɛkrɛma ase .
5. Ma ɛntetew wɔ n’ankasa so. Ntwitwa, ntwitwa, anaa nwe.
6. Mfa nni dwuma nsen dodow a oduruyɛfo no akyerɛ wo.
Nea ɛho hia sen biara no, nnyae saa aduru yi nom gye sɛ wo duruyɛfo ka kyerɛ wo. Sɛ wugyae mpofirim a, ebetumi ama wo tebea no asɛe kɛse na ɛde ɔhaw ahorow a emu yɛ den aba.
Sɛ wonom boro so a , dɛn na wobɛyɛ ?
Sɛ wususuw sɛ woanom saa aduru yi dodo a, kɔ National Poisons Information Center a ɛwɔ Colombo National Hospital no nkyɛn ntɛm ara, anaa kɔ Emergency Department (ETU) a ɛwɔ ayaresabea a ɛbɛn wo no nkyɛn. Wɔakyerɛw saa aduru yi ama wo nkutoo. Mfa nkyerɛ afoforo da.
Na sɛ mepa dose bi nso ɛ?
Eyi nyɛ aduru a ɛsɛ sɛ wɔnom mpɛn pii da biara. Wɔde di dwuma bere a wowɔ ‘off’ bere nkutoo. Enti adwene a ɛne sɛ wɔbɛyera dose bi no mfa ha. Nanso, sɛ woannya ahotɔ mfi wo sɛnkyerɛnne ahorow no mu bere a wode sini biako adi dwuma bere a ‘ɛyɛ adwuma’ akyi a, mfa sini foforo nni dwuma saa bere no. Wo ne wo duruyɛfo nka eyi ho asɛm.
Nnuru afoforo a ebia ɛne aduru yi bedi nkitaho
Apomorphine yɛ aduru a etumi ne nnuru afoforo bi di nkitaho. Enti, ɛho hia sɛ woka nnuru a worenom nyinaa (a vitamin ne nhabannuru ka ho) kyerɛ wo duruyɛfo.
| Mfa Apomorphine nka nnuru yi ho koraa. | |
|---|---|
| Nnuru bi a wɔde sa akisikuru/ɔfe (sɛ nhwɛso no, dolasetron, granisetron, ondansetron, palonosetron) . | |
| Cisapride, Dronedarone, Pimozide, Thioridazine a wɔde yɛ nnuru a wɔde sa yare | |
| Hwɛ yiye paa sɛ worenom Apomorphine ne nnuru yi a. | |
| Nsaden | |
| Aduru a wɔde sa dadwen anaa nna | |
| Nnuru a wɔde sa mogya mmoroso, komayare, ne koma a ɛyɛ den | |
| Nnuru a wɔde sa ɛyaw a wɔde nnubɔne di dwuma | |
| Nitroglycerin a wɔde yɛ aduru | |
| Haloperidol, Metoclopramide, Phenothiazines (sɛ nhwɛso no, chlorpromazine, prochlorperazine) . | |
| Nnuru afoforo a ɛka koma no nnyigyei (ɛma QT ntam kwan kyɛ) . |
Saa nsɛm a wɔahyehyɛ yi nwie pɛyɛ, enti hwɛ hu sɛ wobɛka nnuru a worenom nyinaa akyerɛ wo duruyɛfo.
Nneɛma a ɛsɛ sɛ wohwɛ yiye wɔ ho bere a wode aduru yi redi dwuma no
- Dae ne adwenemhaw: Ebia wobɛte nka sɛ woda anaasɛ wo ho bɛtɔ wo. Enti , nka kar anaa mfa mfiri nni dwuma kosi sɛ wubehu sɛnea aduru yi ka wo. Mma nsɔre mfi baabi a wotena anaa ntena ase mpofirim, titiriw sɛ woabɔ akwakoraa a.
- Dae a wɔda mpofirim: Ebia nnipa binom bɛda mpofirim a wɔmmɔ wɔn kɔkɔ bere a wɔrenom aduru yi. Eyi betumi asi bere a wɔreka kar, wɔrekasa, anaa wɔredidi. Sɛ eyi to wo a, ka kyerɛ wo duruyɛfo ntɛm ara.
- Nkannyan a wontumi nni so: Nnipa binom abɔ amanneɛ sɛ wɔwɔ ɔpɛ a emu yɛ den sɛ wɔde wɔn ho bɛhyɛ dwumadi ahorow te sɛ kyakyatow, nna mu dwumadi, adidi mmoroso, anaa aguadi mu bere a wɔrenom aduru yi. Sɛ wunya nneyɛe a ɛyɛ soronko yi bi a, ka kyerɛ wo duruyɛfo ntɛm ara.
- Akisikuru ne akisikuru: Saa aduru yi betumi ama obi ho ayɛ no yaw kɛse na wafe. Ebia wo duruyɛfo bɛkyerɛw wo aduru foforo de asiw eyi ano. Nanso, ɛnyɛ nnuru a wɔde sa akisikuru nyinaa na wobetumi de aka aduru yi ho. Enti bisa wo duruyɛfo no aduru a ɛfata wo.
- Nitroglycerin a Wɔde Di Dwuma: Sɛ worenom Nitroglycerin a, wo mogya mmoroso betumi akɔ fam mpofirim bere a wonom Apomorphine no. Enti, sɛ worenom Nitroglycerin tablet a ɛwɔ kasa ase a, ɛho hia yiye sɛ wobɛda ansa na woanom ne bere a woanom awie. Eyi betumi aboa ma wɔasiw adwenem naayɛ ne asehwe ano.
Dɛn ne nnuru no mu nsunsuanso bɔne a ebetumi afi mu aba?
| Nsunsuanso bɔne a ɛsɛ sɛ wobɔ wo duruyɛfo amanneɛ ntɛm ara |
|---|
| Allergic reactions - honam ani akisikuru, ɛyaw, anim, anofafa, tɛkrɛma anaa menewa a ɛho ahonhon |
| Koko mu yaw (Angina) - ɛyaw, nhyɛso, anaasɛ ɛyɛ den wɔ koko, kɔn, akyi, anaa abasa mu |
| Adwene a ɛyɛ basaa, nsusuwii hunu |
| Mpofirim ara a ɔda bere a ɔreyɛ da biara da nnwuma |
| Nsakrae a ɛba koma mu - koma bɔ ntɛmntɛm anaasɛ ɛnte saa, adwenemhaw, ɔtopae, koko mu yaw, ɔhome a ɛyɛ den |
| Hemolytic anemia - ɔbrɛ a ɛyɛ soronko, mmerɛwyɛ, adwenemhaw, tiyɛ, ahome a ɛyɛ tiaa, nsu a ɛyɛ tumm, honam ani anaa aniwa a ɛyɛ kɔkɔɔ |
| Mogya mmoroso a ɛba fam - adwenemhaw, adwenemhaw, anisoadehu a ɛyɛ kusuu |
| Anim, ano, anaa nipadua atifi a wɔkankye foforo anaasɛ ɛkɔ soro a wontumi nni so |
| Ano anaa menewa mu akuru, kɔkɔɔ, ahonhon, ne ɛyaw |
| Asen, nsa, anaa anan a ɛho ahonhon |
| Akɔnnɔ a wontumi nni so a yɛaka ho asɛm wɔ atifi hɔ (te sɛ kyakyatow, adidi boro so) a ɛba . |
| Nneɛma bɔne a ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo sɛ ɛkɔ so anaasɛ ɛhaw adwene a |
| Nsakrae a ɛba wɔ dɛ mu wɔ anom |
| Dae a ɛma obi da |
| Tipaeɛ |
| Abofono |
| Hwene a ɛretu anaasɛ hwene a ɛyɛ mmerɛw |
Ɔkwan bɛn so na wode aduru no sie na wotow gu?
- Fa sie baabi a mmofra ne afieboa ntumi nkɔ hɔ .
- Fa sie wɔ dan mu hyew a ɛfata (ɛkɔ digrii Celsius 20-25 ntam).
- Fa sie packet a wɔatoto mu no mu kosi sɛ ɛbɛyɛ krado sɛ wode bedi dwuma.
- Bisa wo duruyɛfo ɔkwan a ahobammɔ wom sen biara a wobɛfa so atow nnuru a ne bere atwam anaasɛ enhia bio agu.
Nkrasɛm a Wɔde Kɔ Fie
- Apomorphine sublingual film yɛ aduru a wɔde ma Parkinson yare a ɛba mpofirim ‘off’, na ɛnyɛ aduru a wɔde ma da biara da.
- Ma wo nsa nwo bere a wode eyi redi dwuma no, fa to wo tɛkrɛma ase na ma ɛnwo. Mma nwe anaasɛ nsɛe no da.
- Saa aduru yi betumi ama woate nka sɛ woada, enti hwɛ yiye paa bere a woreyɛ nnwuma a ɛhwehwɛ sɛ wode w’adwene si biribi so, titiriw bere a woreka kar no.
- Sɛ wunya akɔnnɔ a wuntumi nni so anaasɛ ɔhaw afoforo a anibere wom a, ka kyerɛ wo duruyɛfo ntɛm ara.
- Ɛho hia paa sɛ wobɔ wo duruyɛfo amanneɛ wɔ nnuru afoforo a worenom nyinaa ho.
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