Momma yensua nnuru a esiw protease ano a ɛhwɛ mmoawa so no ho ade kɛkɛ.

Sɛ wo duruyɛfo ka kyerɛ wo anaa obi a wunim no sɛ ɔwɔ ɔyare mmoawa te sɛ HIV, Hepatitis C, anaa COVID-19 a, ebia wo ho yeraw wo kakra wɔ nnuru a wɔbɛkyerɛw ama wo no ho. Nsɛmmisa te sɛ, ‘Dɛn ne nnuru yi?’ ne ‘Ɔkwan bɛn so na ɛka nipadua no?’ bra w’adwene mu. Protease inhibitors yɛ nnuru a tumi wom a wobetumi akyerɛw ama wo wɔ mmere a ɛtete saa mu. Ɛwom sɛ ebia edin no yɛ den kakra de, nanso wɔn dwumadi ho hia yiye. Ɛnnɛ, yɛbɛka eyi ho asɛm wɔ ɔkwan a ɛyɛ mmerɛw koraa so, wɔ ɔkwan a wubetumi ate ase so.

Dɛn ne nnuru a esiw protease ano yi?

Sɛ yɛbɛka no tiawa a, eyinom yɛ nnuru bi a wɔde sa mmoawa a wɔde nyarewa ba. Wɔn adwuma titiriw ne sɛ wobesiw mmoawa bi kwan sɛ wɔbɛyɛ ne ho mfonini na wɔatrɛw wɔ yɛn nipadua mu. Ɛte sɛ nea woredi mmoawa no trɛw so.

Wɔtaa de saa aduru yi di dwuma sɛ aduru a ekum ɔyare mmoawa de sa HIV/AIDS . Wɔde sa nyarewa te sɛ hepatitis C ne COVID-19 nso.

Ɛtɔ da bi a, wɔde saa aduru yi nkutoo ma. Nanso mpɛn pii no, sɛ wɔresa nyarewa te sɛ HIV a, wɔde ka nnuru afoforo pii a ekum ɔyare mmoawa ho, te sɛ ‘cocktail’. Yɛfrɛ eyi Antiretroviral Therapy (ART) . Ɛtɔ da bi a, wɔde Protease Inhibitor di dwuma sɛ ade a ɛma aduru foforo yɛ adwuma yiye.

Nyarewa atitiriw bɛn na wɔde saa aduru yi sa?

Wɔapene nnuru kuw a wɔfrɛ no Protease Inhibitors so sɛ wɔmfa nsa ɔyare mmoawa pɔtee kakraa bi nkutoo.

• HIV/AIDS: Wɔde saa nnuru yi di dwuma sɛ ART ayaresa no fã titiriw de siw HIV ano. Wɔde di dwuma nso de yɛ post-exposure prophylaxis (PEP) de siw ɔyare mmoawa ano bere a wɔanya HIV akyi (sɛ nhwɛso no, nna a ahobammɔ nnim).

• Hepatitis C: Wɔde eyinom ka nnuru afoforo a ekum ɔyare mmoawa ho de sa hepatitis C mmoawa no.

• COVID-19: Sɛ obi nya COVID-19 a, ɛtɔ da bi a nnuruyɛfo kyerɛw Protease Inhibitors ahorow abien a wɔaka abom de asiw yare no ano.

Ɔkwan bɛn so na saa aduru yi yɛ adwuma wɔ nipadua no mu?

Sɛ yɛbɛte eyi ase a, momma yɛmfa nhwɛso ketewaa bi. Fa no sɛ virus yɛ obi a ɔpɛ sɛ ɔyɛ keeki. Sɛ ɔbɛyɛ keeki yi (i.e. mmoawa foforo) a, ɛsɛ sɛ otwitwa protein kɛse bi mu nketenkete. Saa protein nketenkete yi ne ‘nneɛma’ a wɔde yɛ mmoawa foforo.

Ɛha yi, ‘Protease’ yɛ enzyme a ɛyɛ adwuma te sɛ ‘scissors’ a ɛtwa protein ribbon kɛse no.

Aduru a yɛde ma, kyerɛ sɛ...Nea ‘protease inhibitor’ yɛ ne sɛ esiw ‘scissors’ (protease enzyme) no kwan sɛ ɛnyɛ adwuma. Sɛ ntwamutam no gyae adwumayɛ a, mmoawa no ntumi ntwa ‘nneɛma’ a ehia na wɔde ayɛ mmoawa foforo. Afei mmoawa no ntumi nsan nkɔ nipadua no mu na ɛnyɛ ne ho mfonini. Ɛno ne nokware a ɛnyɛ den no.

Dɛn ne Protease Inhibitors ahorow a wɔtaa de di dwuma?

Esiane sɛ mmoawa biara wɔ n’ankasa protease enzyme soronko nti, wɔde nnuru ahorow a esiw protease ano di dwuma de sa HIV, Hepatitis C, ne COVID-19.

Ɔkwan a ɛnyɛ den bi wɔ hɔ a wobɛfa so ahu nnuru yi din.

• Nnuru a wɔde sa HIV taa ba awiei wɔ ‘-navir’ mu.
• Wɔn a wɔde ma wɔ hepatitis C ho no fi ase de asɛmfua ‘-previr’ akyi.

Pon a ɛwɔ ase ha no betumi akyerɛkyerɛ eyi mu akɔ akyiri.

Mɛyɛ dɛn apaw aduru a ɛfata ama me?

Oduruyɛfo a ɔresa wo yare no na osi eyi ho gyinae. Osusuw nneɛma pii ho bere a ɔresi saa gyinae yi.

• Wo virus yareɛ: sɛ ɛyɛ HIV, hepatitis C, anaa COVID-19.
• W’akwahosan nyinaa: Sɛ́ ebia wowɔ nyarewa afoforo te sɛ asikreyare, mogya mmoroso, asaabo anaa mmerɛbo mu yare no.
• Nnuru afoforo a worenom mprempren: Eyi ho hia yiye efisɛ nnuru bi tumi ne Protease Inhibitors yi di nkitaho.
• So woanom nnuru foforo bi a wɔde sa yare yi pɛn?
• Virus no su a wowɔ: Virus no bi ntumi nyɛ nnuru bi ho dwuma.
• Nneɛma bɔne a ebetumi afi mu aba: Paw aduru a ɛfata wo nipadua yiye na enni nsunsuanso bɔne kakraa bi.

Mfaso bɛn na ɛwɔ saa aduru yi a wɔde di dwuma so?

Mfaso a ɛwɔ nnuru yi so no dɔɔso yiye.

• Sɛ́ ART ayaresa no fã no, wobetumi adi HIV so akodu baabi a wontumi nhu wɔ nipadua no mu.
• Ɛboa ma wɔsa hepatitis C yare no koraa .
• Sɛ wo nya COVID-19 a, ɛboa ma yareɛ no nnyɛ den .

Dɛn ne nsunsuanso bɔne ne nsɛnnennen a ebetumi afi mu aba?

Te sɛ aduru biara no, Protease Inhibitors betumi de ɔhaw ahorow aba. Nanso, ɛnyɛ obiara na onya bi. Afei nso, ɛsono nea egyina aduru a wonom ne w’akwahosan tebea so.

Bere tenten ahe na ɛsɛ sɛ menom saa aduru yi?

Eyi gyina yare a wowɔ no so.

• HIV: Esiane sɛ wonnya nnyaa HIV ano aduru koraa nti, ɛho hia sɛ wɔsa yare wo nkwa nna nyinaa. Ebia akwan a wɔfa so sa yare ne nnuru a wɔde sa yare no bɛsakra bere a bere kɔ so no.
• Hepatitis C: Mpɛn pii no, sɛ wɔde adapɛn anaa asram kakraa bi sa yare yi a, wobetumi asa.
• COVID-19: Wɔtaa de nnuru a ekum ɔyare mmoawa ma COVID-19 nnanu.

So nneɛma bi wɔ hɔ a metumi ayɛ na ama ayaresa no ayɛ mmerɛw?

Yiw, koraa. Nneɛma kakraa bi wɔ hɔ a wubetumi ayɛ de atew nsunsuanso bɔne so na ama ayaresa no ayɛ yiye.

• Fa w’aduru no sɛnea oduruyɛfo no ka kyerɛ wo no pɛpɛɛpɛ, wɔ bere ano, na ntwa do biako mpo so.
• Nom nsu pii.Eyi boa ma wosiw nneɛma te sɛ asaabo mu abo ano.
• Kwati sɛ wobɛnom nnuru afoforo a ebetumi ne wo nnuru no adi nkitaho. Bisa wo duruyɛfo no eyi ho asɛm.
• Ɛsɛ sɛ wɔnom nnuru bi ka aduan ho. Yɛbɛhwɛ saa asɛm no akɔ akyiri.

Dɛn nti na Protease Inhibitors binom ka sɛ ɛsɛ sɛ wɔde ka aduan ho?

Ntease bi wɔ hɔ a enti ɛte saa. Protease inhibitors bi, titiriw nea wɔde ka aduan a srade wom ho no, yɛn dwensɔtwaa twetwe yiye. Eyi ma aduru no tumi yɛ kɛse. Enti hwɛ hu sɛ wubebisa wo duruyɛfo sɛ ebia ɛsɛ sɛ wonom w’aduru no ansa na woanom, bere a woadi akyi, anaasɛ wode ka ho.

Bere bɛn na ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn?

Sɛ wunya ɔhaw foforo biara a wonhwɛ kwan, anaasɛ wowɔ nsɛmmisa bi fa w’ayaresa no ho a, ntwentwɛn wo nan ase sɛ wo ne wo duruyɛfo bɛkasa.

Sɛ wuhu nneɛma bɔne a anibere wom a edidi so yi mu biara a, hwehwɛ aduruyɛfo afotu ntɛm ara. Kɔ ayaresabea bi Dwumadibea a Ɛho Hia Ntɛmntɛm (ETU) ntɛm ara sɛnea wubetumi.

• Huraeɛ
• Adwene a ɛyɛ basaa anaasɛ adwene a ɛsakra
• Aniwa anaa honam ani a ɛyɛ kɔkɔɔ (Jaundice) .
• Akuru a ɛyɛ yaw, ɛyɛ akisikuru, a ɛtrɛw
• Yafunu mu yaw a emu yɛ den
• Ɔfe a emu yɛ den a wontumi nsiw ano

Protease inhibitors yɛ nnuru a ɛho hia paa na ɛgye nkwa wɔ nyarewa te sɛ HIV ne Hepatitis C. Sɛ wowɔ nsɛmmisa anaa nsɛm bi a ɛhaw wo wɔ saa ayaresa yi ho a, wo ne wo duruyɛfoɔ nka ho asɛm pefee. Wobetumi aboa wo ma woayɛ ayaresa nhyehyɛe a ɛbɛyɛ adwuma yiye ama wo.