So wo nkwaa yɛ wo yaw mpofirim anaasɛ ɛhohoro? Eyi betumi ayɛ pseudogout!

So woasɔre anɔpa na mpofirim ara woahu sɛ nkwaa bi te sɛ wo kotodwe anaa wo nsateaa ayɛ kɔkɔɔ, ahonhon, na ɛyaw a wuntumi nnyina ano pɛn? Anaasɛ ebia woda anadwo a wunhyiaa ɔhaw biara, na afei wosɔree anɔpa a na wote ɛyaw a emu yɛ den yi? Ɛtɔ mmere bi a eyi betumi ayɛ tebea a yensusuw ho mpo, te sɛ ntini mu yare, a ɛyɛ tebea a ɛde nkwaa a ɛho ahonhon ba. Yɛrebɛka yareɛ a ɛte saa ho asɛm nnɛ.

Dɛn ne eyi (Pseudogout)?

Sɛ yɛbɛka no tiawa a, pseudogout nso yɛ ntini mu yare bi. Nanso ɛba mpofirim, a wɔmfa kɔkɔbɔ biara mma , a ɛyaw a emu yɛ den ne wo nkwaa ahonhon. Ɛte sɛ nea biribi rewia wo ho.

Ɛwom sɛ tebea yi (pseudogout) betumi aka wo nipadua no nkwaa biara de, nanso wɔtaa hu wɔ saa nkwaa yi mu:

• Wɔ nkotodwe mu
• Wɔ nsa ne nsateaa mu
• Wɔ mmati mu
• Wɔ asen ne nkwaa a ɛfa ho mu
• Wɔ nsateaa mu
• Wɔ ankles no mu

Nnuruyɛfo de din afoforo pii di dwuma ma saa tebea yi (Pseudogout). Ebia woate din ahorow yi:

• Calcium pyrophosphate deposition (CPPD): Eyi kyerɛ sɛ wɔde nnuru bi a wɔfrɛ no calcium pyrophosphate gu nkwaa no mu.
• Calcium pyrophosphate ntini mu yare: Eyi yɛ nkwaa a ɛyɛ hyew a calcium pyrophosphate de ba.
• Chondrocalcinosis: Eyi kyerɛ calcium a ɛba nkwaa a ɛyɛ mmerɛw a wɔfrɛ no cartilage no mu.

Saa din ahorow yi nyinaa kyerɛ ayaresa tebea koro. Enti, sɛ oduruyɛfo no bɔ saa din yi mu biako a, mma ɛnhaw wo, ɛkyerɛ eyi (Pseudogout).

Nsonsonoe bɛn na ɛwɔ Pseudogout ne Gout ntam ?

Afei ebia woresusuw sɛ, "Oh, so eyi ne nkwaa mu yare koro no ara a wɔfrɛ no Gout ?" Nokwarem no, nsɛdi pii wɔ abien no ntam, ɛno nti na wɔfrɛ no ‘pseudo-gout’. Asɛmfua ‘pseudo’ kyerɛ ‘atoro’ anaa ‘atoro’. Enti eyi te sɛ ‘pseudo gout ’.

Nanso nsonsonoe a ɛda adi pefee wɔ abien no ntam.

• Gout ba bere a nnuru bi a wɔfrɛ no uric acid pii wɔ wo mogya mu (tebea a wɔfrɛ no hyperuricemia). Afei saa uric acid ahwehwɛ a ano yɛ nnam yi kɔhyɛ nkwaa no mu, na ɛde ɔfe ba.
• Pseudogout fi ahwehwɛ soronko koraa a ɛboaboa ano wɔ nkwaa no mu. Wɔfrɛ no calcium pyrophosphate (CPP) ahwehwɛ. Ɛno nti na wɔsan frɛ no ``Calcium pyrophosphate deposition''.

Nsonsonoe foforo ne, gout.Gout taa ka nkwaa a wo nansoaa kɛse no ne wo nan di nkitaho (metatarsophalangeal (MTP) nkwaa) no. Mpɛn pii no, pseudogout mfa saa nkwaa no ho. Mmom no, ɛtaa ka nkwaa akɛse te sɛ nkotodwe ne nsateaa.

Dɛn ne (Pseudogout) ho sɛnkyerɛnne?

Nsɛnkyerɛnne bɛn na wubehu wɔ saa tebea yi mu (Pseudogout)? Momma yɛnhwɛ:

• Nkwaa mu yaw a ɛba mpofirim a wontumi nnyina ano ne sɛnkyerɛnne titiriw no.
• Wora kɔla a ɛsakra anaasɛ ɛyɛ kɔkɔɔ. Ebia were a atwa nkwaa a ɛyɛ yaw no ho ahyia no bɛyɛ kɔkɔɔ.
• Rehono. Nkwaa a ɛka no no ho ahonhon kɛse.
• Ntini a ɛyɛ den wɔ nkwaa no mu. Ɛbɛyɛ den sɛ wobɛkotow anaa wobɛteɛteɛ nkwaa no.
• Ɔhyew a wɔte nka wɔ nkwaa no mu anaa ne ho. Ebia wobɛte ɔhyew nka bere a wode wo nsa ka ho no.

Saa sɛnkyerɛnne ahorow yi ntra hɔ daa. Wɔba na wɔkɔ. Wɔba wɔ asorɔkye mu. Yɛfrɛ saa ogyaframa anaa ntua. (Pseudogout) ‘Ntuo’ bi fi ase mpofirim. Sɛ́ anka wobɛte nka sɛ wo yare no ho sɛnkyerɛnne no reyɛ kɛse nkakrankakra no, ebia wubenya wo yare no nyinaa prɛko pɛ. ‘Ntuo’ a ɛte sɛɛ betumi adi nna kakraa bi kosi adapɛn kakraa bi, na ɛtɔ mmere bi mpo a ɛkyɛ.

Dɛn nti na eyi (Pseudogout) ba?

Nea enti titiriw a ɛte saa ne sɛnea yɛadi kan aka no, ade bi a wɔfrɛ no calcium pyrophosphate (CPP) nketenkete a ɛte sɛ powder a ɛbɛgu wo nkwaa a ayɛ wo yaw no mu. Eyinom boaboa ano wɔ ntini a ɛyɛ mmerɛw (ɔfã a ɛyɛ mmerɛw a ɛmma nnompe no ntumi nsɛe wɔn ho wɔn ho) mu wɔ nkwaa no mu ne ntini a ɛyɛ tratraa (synovial membranes) a atwa nkwaa no ho ahyia na ɛma nkwaa no nya nsu a ɛte sɛ ngo no mu. Bere kɔ so no, saa `(CPP)` nneɛma nketenkete yi boaboa ano wɔ nkwaa no mu, na ɛde saa ‘ntua’ a ɛyɛ yaw no ba.

Nanso, nyansahufo da so ara nnim nea enti a wo nipadua no yɛ `(CPP)` pii ne nea enti a ɛkɔ wo nkwaa mu. Nhwehwɛmu ahorow bi kyerɛ sɛ ebia efi awosu mu, a ɛkyerɛ sɛ sɛ w’awofo wɔ bi a, wo mma nso wɔ asiane mu sɛ wobenya bi. Wɔ afoforo fam no, tebea no betumi aba bere a wɔapira wɔn nkwaa akyi. Wosusuw nso sɛ nipadua mu nneɛma a ɛsakra anaa nipadua no mu tebea horow bi (pseudogout) nso betumi de aba.

Hena na ɔwɔ asiane kɛse mu sɛ obenya pseudogout?

Ɛwom sɛ obiara betumi anya pseudogout de, nanso ɛtaa ba nnipa a wɔadi boro mfe 65. Nea ɛka ho no, nnipa a wɔwɔ tebea horow bi a enni sabea no wɔ asiane kɛse mu sɛ wobenya pseudogout. Nhwɛsoɔ:

• Magnesium a ɛba mogya mu (Hypomagnesemia) .
• Hyperparathyroidism a ɛma obi ho kyere no
• Thyroid yareɛ
• Dade a ɛboro so wɔ nipadua no mu (Hemochromatosis) .
• Hypophosphatasia (mmoa a ɛwɔ nnompe mu a ɛmfata) .
• Nnompe a ɛyɛ mmerɛw
• Asaabo mu yare a enni sabea (CKD) .

Afei nso, nnipa a wɔwɔ ntini mu yare afoforo (pseudogout) dedaw nso betumi anya bi. Nhwɛso ahorow:

• Gout
• Nnompe mu yare (nkwaa mu yaw) .
• Ntini mu yare a ɛma ntini mu yare
• Ntini mu yare a ɛba wɔ ahodwiriw akyi

Dɛn ne nsɛnnennen a ebetumi afi pseudogout mu aba?

Sɛ wɔansa a, saa tebea yi (Pseudogout) betumi ama ‘ogyaframa’ a ɛyɛ yaw a ɛtaa ba na emu yɛ den. Eyi kyerɛ sɛ wo yaw no bɛkɔ so ayɛ kɛse. Wɔ nnipa binom fam no, sɛ saa ‘CPP’ asinasin yi kɔ nnompe a ɛwɔ kɔn no atifi no ho a, ebetumi nso de sɛnkyerɛnne ahorow te sɛ tiyɛ anaa kɔn mu yaw aba .

Ɔkwan bɛn so na nnuruyɛfo hu sɛ obi anya pseudogout?

Sɛ wokɔ oduruyɛfo nkyɛn a, ɔbɛhwɛ wo na wayɛ nhwehwɛmu bi de ahu sɛ wowɔ pseudogout anaa. Oduruyɛfo no bɛhwɛ wo nkwaa mu na wabisa wo yare no ho sɛnkyerɛnne. Saa bere no, hwɛ hu sɛ wobɛka nea edidi so yi pefee:

• Bere bɛn na wudii kan huu saa sɛnkyerɛnne ahorow yi?
• Ɛte sɛ nea saa sɛnkyerɛnne ahorow yi ba na ɛkɔ.
• So saa sɛnkyerɛnne ahorow yi kɔ soro (anaasɛ ɛso tew) wɔ dwumadi ahorow bi mu anaasɛ da no mu mmere pɔtee bi mu?

Mpɛn pii no, wo duruyɛfo no bɛfa nsu bi afi wo nkwaa mu (joint aspiration anaa arthrocentesis). Nea ɛka eyi ho ne sɛ wɔde ade teateaa bi bɛhyɛ nkwaa a ɛyɛ yaw no mu na wɔafa nsu no bi, na afei wɔde akɔ aduruyɛdan mu ma wɔayɛ mu nhwehwɛmu. Lab no bɛhwɛ no wɔ microscope ase ahwɛ sɛ CPP mu nneɛma nketenkete bi wɔ hɔ anaa. Eyi ne ɔkwan a eye sen biara a wobɛfa so asi pseudogout so dua.

Ma ɛntra w’adwenem sɛ ebia wobɛte ɛyaw bi nka bere a wunya nsu wɔ saa nkwaa yi mu no, titiriw sɛ nkwaa no ahonhon kɛse na ɛyɛ yaw a. Nanso, wo duruyɛfo betumi ama wo aduru bi a ɛma wo ho tɔ wo na aboa ma ɛyaw no so atew.

Nea ɛka ho no, oduruyɛfo no betumi ayɛ mfoninitwa nhwehwɛmu nso de ahwɛ sɛ calcium wɔ nkwaa no mu (chondrocalcinosis). Ebia eyi bi ne:

• X-ray ahorow a wɔde yɛ
• CT scan (CT scan - kɔmputa so mfoninitwa afiri) .
• MRI scan `(MRI - magnetic resonance mfoninitwa)`
• Ultrasound scan `(Nnyigyei a ɛboro so)`

Wubetumi de sɔhwɛ ahorow te sɛ.

Dɛn ne ayaresa a eye sen biara a wɔde sa (Pseudogout)?

Wo duruyɛfo bɛkamfo ayaresa ahorow a ɛbɛboa ma woadi wo sɛnkyerɛnne ahorow so na ama pseudogout ntua a ɛtaa ba no so atew. Ayaresa a wɔtaa yɛ ne nnuru.

• NSAIDs (N.S.A.I.D. - nnuru a ɛnyɛ steroid a ɛko tia ɔyare mmoawa): Eyinom yɛ nnuru a wɔde kum ɛyaw ne nnuru a ɛko tia ɔyare mmoawa. Wubetumi atɔ nnuru a wɔtɔn te sɛ ibuprofen anaa naproxen. Nanso, ɛnyɛ obiara na ɛsɛ sɛ ɔde saa NSAID ahorow yi di dwuma.Titiriw sɛ wowɔ akwahosan ho haw afoforo a. Enti, mfa saa aduru yi nni dwuma a wo ne oduruyɛfo nkasa, na mfa nni dwuma bere nyinaa bɛboro nna du.
• Corticosteroids: Eyinom yɛ nnuru a ano yɛ den a ɛko tia ɔyare mmoawa a oduruyɛfo kyerɛw ma. Wobetumi de ama wo sɛ nnuru a wode bɛnom anaasɛ sɛ cortisone a wɔtow kɔ nkwaa a ayɛ basaa no mu tẽẽ.
• Colchicine: Eyi nso yɛ aduru a oduruyɛfo bi kyerɛw ma obi de tew ɔfe ne ɛyaw so. (Pseudogout) Saa aduru yi tu mpɔn kɛse sɛ wɔnom wɔ nnɔnhwerew 24 akyi wɔ ntua no ase a. Ɛtɔ mmere bi a wo duruyɛfo betumi aka akyerɛ wo sɛ fa saa aduru yi a ɛba fam bere tenten na ama ntua a ɛtaa ba no so atew.
• Biologic injections: Ɛtɔ mmere bi a wo duruyɛfo betumi akamfo injections te sɛ anakinra anaa canakinumab aboa ma woadi pseudogout ntua so. Saa nnuru yi yɛ adwuma wɔ ɔkwan a ɛte sɛ colchicine so. Ɛwom sɛ Aduan ne Nnuru Dwumadibea (FDA) apene so sɛ wɔnsa ntini mu yare afoforo de, nanso wonnya nnyee wɔn mmae wɔ aban kwan so sɛ wɔnsa pseudogout. Eyi kyerɛ sɛ ebia wo insurance no rentua wɔn ka, na ebia ne bo yɛ den sen ayaresa afoforo.

Sɛ mewɔ pseudogout a, dɛn na ɛsɛ sɛ mehwɛ kwan?

Sɛ wowɔ pseudogout a, wubetumi ahwɛ kwan sɛ wubenya saa sɛnkyerɛnne ahorow yi ntua a ɛba na ɛkɔ. Saa ntua yi betumi ayɛ nea ɛtaa ba sɛ woanhwehwɛ ayaresa amfi oduruyɛfo nkyɛn a.

Sɛ worenya ayaresa mpo a, mpɛn dodow a ‘ntua’ yi ba no betumi akɔ soro bere a wo nyin no. Eyi yɛ ade a ɛfata.

So wobetumi asiw pseudogout ano?

Nokwarem no, mprempren ɔkwan pɔtee biara nni hɔ a wɔbɛfa so asiw pseudogout ano. Nanso nyansahufo da so ara reyɛ nhwehwɛmu de ahu nea enti pɔtee a yɛn nipadua yɛ saa ``(CPP)`` asinasin yi pii dodo.

W’akwahosan tebea afoforo (e.g., asikreyare, mogya mmoroso) a wobɛhwɛ so no betumi aboa ma wɔatew mpɛn dodow a saa (pseudogout) ‘ntua’ yi so.

Nnipa binom fi awosu mu nya yare no ho sɛnkyerɛnne mpɛn pii sen afoforo. Sɛ wunya pseudogout ‘ntua’ a, ɛnyɛ wo mfomso, na nsusuw sɛ ɛyɛ nea woayɛ bɔne nti. Mpɛn pii no, nneɛma biara nni hɔ a ɛkanyan obi tẽẽ a wubetumi asesa anaasɛ wubetumi asiw ano.

Bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn?

Sɛ wote ɛyaw a emu yɛ den mpofirim wɔ wo nkwaa biako mu, titiriw sɛ nkwaa no ahonhon, ayɛ kɔkɔɔ, anaa ne kɔla asesa a, kɔ oduruyɛfo nkyɛn ntɛm ara. Pseudogout ho sɛnkyerɛnne te sɛ gout , ɔyare mmoawa bi, ne tebea afoforo a ɛsɛ sɛ wɔsa no ntɛm ara de no ara pɛ.

Afei nso, sɛ worenya pseudogout ntua pii sen sɛnea wotaa yɛ, anaasɛ wo sɛnkyerɛnne ahorow no mu yɛ den sen sɛnea ɛtaa ba a, ka ɛno nso kyerɛ wo duruyɛfo.

Nsɛm bɛn na ɛsɛ sɛ mibisa oduruyɛfo no?

Sɛ wuhyia oduruyɛfo no a, wubetumi abisa nsɛm te sɛ eyinom:

• So mewɔ pseudogout, anaasɛ ntini mu yare foforo?
• Sɔhwɛ ahorow bɛn na ɛsɛ sɛ meyɛ?
• Dɛn na metumi ayɛ de asiw daakye (pseudogout) ‘ntua’ ano?
• Aduru bɛn na eye sen biara a mede besiw me yare no ho sɛnkyerɛnne ano?

So aduan ne anonne betumi akanyan ntua (pseudogout)?

Eyi yɛ asɛmmisa a nnipa pii bisa, na ɛyɛ asɛm a ɛho hia. So nneɛma a wudi na wonom no betumi akanyan pseudogout ntua? Mpɛn pii no, mmuae no yɛ dabi. Eyi yɛ nsonsonoe titiriw a ɛda pseudogout ne gout ntam no mu biako .

Nnuan bi a wodi (titiriw nam ne mpataa a purine pii wom, ne nsa te sɛ beer) betumi ama obi anya gout . Nea enti a ɛte saa ne sɛ, sɛ wɔyam saa nnuan no a, nipadua no ma uric acid pii ba. Ɛno nti na wotu nnipa a wɔwɔ gout fo sɛ wonni aduan a purines nnim akyi.

Nanso, wɔ pseudogout mu no, CPP asinasin no nboaboa ano wɔ nipadua no mu te sɛ uric acid. Enti, mpɛn pii no, pseudogout ne nea wudi anaa wonom nni abusuabɔ tẽẽ.

Nokwarem no, ebia wo duruyɛfo betu wo fo sɛ di anaa kwati nnuan bi na ama w’akwahosan nyinaa akɔ so anaasɛ woadi tebea afoforo a ebia wowɔ ho dwuma, nanso ɛnyɛ pseudogout titiriw.

Ɛwom sɛ edin Pseudogout no kyerɛ ‘atoro’ gout , nanso ɛyaw, ɔfe, ne ɔhaw a wote nka no nyɛ atoro. Ebetumi ayɛ den ankasa sɛ wobɛgyina ano. Ebetumi ayɛ abasamtu sɛ wuntumi nsiw Pseudogout ano. Nanso, nnipa pii betumi de nnuru a ɛfata a wɔaka abom adi dwuma de atew nkɛntɛnso a Pseudogout nya wɔ wɔn da biara da asetra so no so.

Ebia wubenya ntua bere ne bere mu, nanso wo duruyɛfo betumi aboa wo ma woanya akwan a wobɛfa so adi wo sɛnkyerɛnne ahorow no ho dwuma.

Nneɛma bɛn na ɛho hia paa a ɛsɛ sɛ yɛkae fi saa asɛm yi mu?

Okay, enti momma yɛmmɔ nneɛma bi a ɛsɛ sɛ wode sie w’adwene mu mfi nea yɛaka ho asɛm no mu no mua:

• Pseudogout yɛ ntini mu yare bi a ɛba mpofirim, na nkwaa mu yaw kɛse na ɛhoa.
• Eyi fi asinasin a wɔfrɛ no calcium pyrophosphate (CPP) a ɛtɔ nkwaa no mu.
• Nea ɛnte sɛ gout , ɛnyɛ aduan ne anonne na ɛma tebea yi mu yɛ den tẽẽ.
• Sɛ wuhu saa sɛnkyerɛnne ahorow yi a, hwɛ hu sɛ wobɛkɔ oduruyɛfo nkyɛn ma wahu yare no pɛpɛɛpɛ.
• Ayaresa a wobetumi apaw bi ne nnuru a wɔde kum ɛyaw ne nnuru a ekum ɔyare mmoawa, a ebetumi aboa ma wɔadi yare no ho sɛnkyerɛnne ahorow so.
• Ɛwom sɛ wontumi nsiw eyi ano koraa de, nanso ayaresa betumi ama asetra atu mpɔn.

Enti, sɛ wo anaa obi a wunim no wɔ saa sɛnkyerɛnne ahorow yi a, nsuro sɛ wobɛkɔ oduruyɛfo nkyɛn na woanya afotu. Sɛ wohu yare no ntɛm na wɔsa yare a, ɛho hia yiye.

` Pseudogout, Chondrocalcinosis, CPPD, Ntini mu yaw, Nkwaa a ɛho ahonhon, Calcium pyrophosphate, Ntini mu yare