So wunim Rasagiline aduru a wɔde sa Parkinson yare no?

So wo duruyɛfo aka akyerɛ wo anaa obi a wunim no sɛ ɔwɔ Parkinson yare no? Afei ebia woate aduru bi a wɔfrɛ no Rasagiline ho asɛm. Ɛyɛ aduru titiriw bi kakra. Enti ɛnnɛ, momma yɛnka nea Rasagiline yɛ, sɛnea wɔde di dwuma, ne nea ɛsɛ sɛ wohwɛ yiye wɔ ho. Momma yɛnka ho asɛm tiawa, te sɛ nea yɛne yɛn adamfo bi rekasa.

Aduru bɛn na Rasagiline yɛ?

Sɛ yɛbɛka no tiawa a, Rasagiline yɛ nnuru a esiw monoamine oxidase ano, a ɛka nnuru bi a wɔfrɛ no Monoamine Oxidase Inhibitors (MAOIs) ho. Wɔde di dwuma titiriw de siw Parkinson Yare no ho sɛnkyerɛnne ahorow so . Ebia wubehu saa aduru yi wɔ din Azilect ase. Nanso, ɛtɔ mmere bi a nnuruyɛfo betumi akyerɛw saa aduru yi ama tebea afoforo. Enti sɛ wowɔ nsɛmmisa bi a, ɛbɛyɛ papa sɛ wubebisa wo duruyɛfo anaa nnuruyɛfo.

Nneɛma bɛn na ɛsɛ sɛ meka kyerɛ oduruyɛfo no ansa na manom saa aduru yi?

Ansa na wubefi ase anom Rasagiline no, ɛho hia sɛ woka saa nsɛm yi kyerɛ wo duruyɛfo. Eyi ho hia yiye efisɛ egyina saa nsɛm yi so na oduruyɛfo no besi gyinae sɛ ebia saa aduru yi fata wo anaasɛ ɛnsɛ, ne dodow a ɔde bɛma wo.

• Sɛ wowɔ mogya mmoroso anaasɛ mogya mmoroso a ɛba fam a .
• Sɛ woadi kan anya akisikuru a .
• Sɛ woyɛ ɔsadweam a .
• Sɛ wowɔ mmerɛbo mu yare biara a .
• Sɛ wowɔ adwenemyare bi a , sɛ nhwɛso no, sɛ woadi kan anya tebea bi te sɛ adwenemhaw a.
• Sɛ wowɔ narcolepsy, nna mu haw .
• Sɛ wowɔ nna mu ahomegye, tebea a ɛma wugyae home bere a woada .
• Sɛ wo ho yɛ wo hyew wɔ rasagiline, nnuru afoforo, nnuan, nnuru a wɔde yɛ nneɛma, anaa nneɛma a wɔde siesie nneɛma ho a.
• Sɛ woanyinsɛn, worebɔ mmɔden sɛ wubenyinsɛn, anaa worema nufu a, hwɛ hu sɛ wobɛka eyi ho asɛm.

Ɛho hia paa ma w’ankasa akwahosan sɛ wobɛka saa nneɛma yi ho asɛm akyerɛ wo duruyɛfo a womfa nsie.

Ɔkwan bɛn so na ɛsɛ sɛ mede saa aduru yi di dwuma?

Okay, afei momma yɛnhwɛ sɛnea yɛbɛfa saa aduru yi.

• Ɛsɛ sɛ wɔnom saa aduru yi wɔ ano, na wɔde nsu kuruwa ka ho .
• Fa nnuru a wo duruyɛfo akyerɛw ama wo no di dwuma sɛnea wɔakyerɛ wɔ nnuru a wɔakyerɛw ama wo no so pɛpɛɛpɛ.
• Fa dodow a wɔakyerɛw ama no no wɔ bere a wɔahyɛ no mu. Nnom nea ɛboro nea oduruyɛfo no aka akyerɛ wo no da.
• Mma nnnyae saa aduru yi nom mpofirim a wunnya wo duruyɛfo afotu.Saa a wobɛyɛ no betumi de ɔhaw ahorow aba wo so.
• Akyinnye biara nni ho sɛ ɛsɛ sɛ wo ne mmofra oduruyɛfo kasa fa saa aduru yi a wode bɛma mmofra nkumaa ho . Ɛtɔ mmere bi a, ebia ɛho behia sɛ wɔhwɛ yiye titiriw.

Na sɛ mepa nnuru dodow bi nso ɛ?

Fa no sɛ wo werɛ afi sɛ wobɛnom nnuru dodow bi. Sɛ eyi ba a, fa no bere a woakae ara pɛ. Nanso, sɛ ɛkame ayɛ sɛ bere aso sɛ wobɛma wo dodow a edi hɔ no a, twa dodow a woayera no so na fa wo dodow a edi hɔ no wɔ bere a woahyɛ da ayɛ no mu. Mfa nnuru mmɔho abien anaa nea ɛboro so esiane biribiara nti.

Na sɛ menom nnuru pii nso ɛ?

Sɛ wususuw sɛ woanom nnuru pii sen sɛnea wususuw a, frɛ ayaresabea dan a wɔhwɛ wɔn a wɔwɔ ayaresa a egye ntɛmpɛ anaa beae a wɔhwɛ awuduru so a ɛbɛn wo ntɛm ara . Eyi ho hia paa.

Kae: Wɔakyerɛw saa aduru yi ama wo nkutoo. Mfa w’aduru nkyɛ afoforo, efisɛ ebetumi apira wɔn.

Dɛn ne nkitahodi ahorow a ebetumi ne aduru yi adi nkitaho? (Nkitahodi ahorow) .

Eyi yɛ asɛm a ɛho hia paa. Rasagiline tumi ne nnuru ne nnuan afoforo bi di nkitaho. Wei kyerɛ sɛ, sɛ woka bom a, wobɛtumi anya nsunsuansoɔ bɔne a ɛyɛ hu anaasɛ Rasagiline dwumadie so bɛtew/akɔ soro.

Mfa nnuru yi nka Rasagiline ho:

Nnuru bi a ɛnsɛ sɛ wode di dwuma da sɛ worenom Rasagiline a ni:

• Atomoxetine a wɔde yɛ aduru
• Nnuru bi a wode sa adwenemhaw - bisa wo duruyɛfo no eyi ho asɛm.
• Cyclobenzaprine a wɔde di dwuma
• Dextromethorphan (wohu wɔ ɔfe aduru bi mu) .
• Linezolid a wɔfrɛ no linezolid
• MAOI afoforo (sɛ nhwɛso no, Carbex, Eldepryl, Xadago, Marplan, Nardil, Parnate). Sɛ worenom MAOI foforo a, ka kyerɛ wo duruyɛfo .
• Meperidine a wɔde di dwuma
• Methadone a wɔde di dwuma
• Methylene Blue a ɛyɛ bruu
• Propoxyphene a wɔde yɛ nnuru
• Nnuru a ɛkanyan obi ma obi adwene mu yɛ no yaw, obi mu duru a ɛso tew, anaasɛ nna a ontumi nna.
• St. John’s Wort (eyi yɛ nhabannuru a nnipa binom nom de nya adwene mu yiyedi) .
• Tramadol a wɔde di dwuma
• Tryptophan a ɛyɛ aduru a wɔfrɛ no Tryptophan
• Viloxazine a wɔde ma

Saa nneɛma yi nso betumi ne Rasagiline adi nkitaho:

Nea edidi so yi nso betumi de ɔhaw aba Rasagiline ho, enti sɛ worenom a, ka kyerɛ wo duruyɛfo :

• Nsaden
• Amiodarone a wɔde yɛ aduru
• Nnuru bi a ekum ɔyare mmoawa, s.e. Ciprofloxacin, Norfloxacin a wɔde yɛ aduru a wɔfrɛ no Norfloxacin
• Nnuru ahorow a wɔde kum akisikuru a wɔde sa akisikuru, ɔfe, ne atiridiinini
• Carbamazepine a wɔde di dwuma
• Nnuru bi a ɛboa wo ma woda
• Cimetidine a wɔde di dwuma
• Nnuru bi a wɔde sa anom a ɛyɛ den anaa aniwa a ɛyɛ den (decongestants) .
• Mmea hormone ahorow, s.e. estrogen ahorow a ɛma nipadua no yɛ adwuma
• Furazolidone a wɔde yɛ aduru
• Isoniazid a wɔde yɛ nnuru
• Nnuru a wɔde sa dadwen anaa adwenemyare
• Nnuru a ɛma obi dwo bere a wɔreyɛ oprehyɛn no
• Mexiletine a wɔde yɛ aduru
• Nnuru a wɔde yɛ nnubɔne a wɔde sa ɛyaw
• Procarbazine a wɔde ma
• Theophylline a wɔde yɛ nnuru
• Tizanidine a wɔde di dwuma
• Yohimbine na ɔkyerɛwee
• Zileuton na ɔkyerɛwee

Saa list yi nka nkitahodi ahorow nyinaa ho. Enti, ka nnuru a worenom nyinaa ho asɛm kyerɛ wo duruyɛfo (wɔakyerɛw ama wo, a wontua hwee, nhabannuru, vitamin ahorow), ne sɛ wonom sigaret, wonom nsa, anaa wode nnuru afoforo di dwuma a.

Nneɛma bɛn na ɛsɛ sɛ yɛhwɛ yiye wɔ ho bere a yɛde aduru yi redi dwuma no?

Sɛ worenom Rasagiline a, hwɛ nneɛma yi yiye na ama woanya ahobammɔ na woahwɛ ahu sɛ aduru no yɛ adwuma yiye.

• Hwɛ wo duruyɛfo daa: Kɔ wo duruyɛfo nkyɛn sɛnea wɔakyerɛ wo no na hwɛ sɛ wo yare no ho sɛnkyerɛnne no retu mpɔn anaasɛ ɛnte saa, ne sɛ ebia ɔhaw foforo bi wɔ hɔ anaa.
• Dae ne adwenemhaw: Ebia wobɛte nka sɛ woada, wo ho ayɛ wo yaw, anaasɛ w’ani ayɛ kusuu bere a worenom aduru yi no. Enti, nka kar, nnyɛ adwuma wɔ mmeae a ɛkorɔn, anaa mfa mfiri nni dwuma kosi sɛ wubehu sɛnea aduru yi ka wo. Hwɛ yiye bere a wosɔre fi baabi a wotena anaa woda mpa so mpofirim no, titiriw sɛ woabɔ akwakoraa a. Sɛ ɛnte saa a, ebia w’adwene betu na woahwe ase.
• Kwati nsa: Nsa betumi ama woate nka kɛse sɛ woda na wo ho kyere wo. Enti wo ne wo duruyɛfo nka nsa a wobɛnom bere a worenom aduru yi ho asɛm.
• Dae a obi da mpofirim: Eyi ho hia paa. Ebia nnipa binom bɛda mpofirim a wɔmmɔ wɔn kɔkɔ bere a wɔrenom Rasagiline no. Eyi betumi asi bere a woreka kar, worekasa, anaa woredidi. Ebia wobɛda a worente nka sɛ woada. Sɛ eyi to wo a ka kyerɛ wo duruyɛfo ntɛm ara .
• Akɔnnɔ a wontumi nni so: Ebia nnipa binom benya akɔnnɔ a emu yɛ den bere a wɔnom aduru yi, te sɛ nna ho akɔnnɔ, kyakyatow ho akɔnnɔ, sika a wɔsɛe no a wontumi nni so, ne adidi mmoroso. Sɛ wuhyia eyinom mu biara a, nfɛre na ka kyerɛ wo duruyɛfo ntɛm ara.
• Nnuan a Tyramine pii wom: Eyi nso yɛ ade a ɛho hia yiye a ɛsɛ sɛ wususuw ho. Bere a wɔrenom Rasagiline noƐsɛ sɛ wokwati nnuan a nnuru bi a wɔfrɛ no tyramine wom . Sɛ wo ne saa aduru yi ka nnuan a ɛtete saa ho a, wo mogya mmoroso betumi akɔ soro mpofirim wɔ ɔkwan a ɛyɛ hu so (Hypertensive Crisis) .
• Dɛn ne nnuan a tyramine pii wom yi? Mpɛn pii no, wohu tyramine wɔ nnuan a wɔabɔ akwakoraa, a wɔayam, wɔayam no wusiw, wɔasa, na wɔayam mu. Sɛ nhwɛso no, kyiisi a ayɛ dedaw, soseji ahorow bi, bobesa, ne beer.
• Sɛ wopɛ sɛ wuhu eyi ho nsɛm pii a, bisa wo duruyɛfo, nnuruyɛfo, anaa aduannuru ho ɔbenfo ma ɔmma wo nnuan ne anonne a tyramine pii wom.
• Sɛ wote nka sɛ wo ho nyɛ wo dɛ (sɛ nhwɛso no, tiyɛ, wo koko mu yaw, ɛyɛ den sɛ wobɛhome) bere a woadi aduan a tyramine pii wom akyi bere tiaa bi a, ka kyerɛ wo duruyɛfo ntɛm ara.
• Hwɛ yiye wɔ nnuru afoforo ho: Bisa wo duruyɛfo ansa na woanom nnuru a wɔtɔn te sɛ ɔfe ne atiridiinini, hwene mu nsu, ne aniwa mu nsu. Saa nnuru yi betumi ne nnuru a ekum adwenemhaw ne nnuru bi a wɔde kum ɛyaw adi nkitaho.
• Oprehyɛn anaa sẽ ayaresa: Sɛ worekɔyɛ aduruyɛ anaa wo sẽ ho oprehyɛn biara a, ka kyerɛ oduruyɛfo no sɛ worenom rasagiline, efisɛ ebetumi ne nnuru bi a wɔde di dwuma bere a wɔreyɛ oprehyɛn no adi nkitaho.

Dɛn ne aduru yi mu nsunsuanso bɔne a ebetumi afi mu aba?

Te sɛ aduru biara no, Rasagiline betumi de ɔhaw ahorow aba nnipa binom so. Ebi yɛ aniberesɛm, ebi nso nyɛ aniberesɛm saa.

Sɛ wunya saa nsunsuanso bɔne yi a , kɔ oduruyɛfo anaa ayaresabea ntɛm ara :

• Nneɛma a ɛma obi ho yɛ no hyew: Honam ani akisikuru, ɛyaw, anofafa, tɛkrɛma, ne anim a ɛho ahonhon.
• Nkate anaa adwene mu nsakrae: Mpofirim ara a obi bo fuw anaa ne ho yeraw no.
• Nsakrae a ɛba wɔ anisoadehu mu.
• Dae a wobɛda mpofirim bere a woreyɛ nnwuma a ɛfata (e.g., bere a woreka kar).
• Hallucinations: Nneɛma a enni hɔ ankasa a wuhu anaa wote.
• Mogya mmoroso.
• Akɔnnɔ a wontumi nni so, te sɛ kyakyatow foforo anaa nea ɛkɔ soro, nna ho akɔnnɔ, sika a wɔsɛe no a wontumi nni so, ne adidi boro so.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ obi anya mogya mmoroso ho haw: tiyɛ a emu yɛ den, adwene a ɛyɛ basaa, aniwa a ɛyɛ kusuu, ne koko mu yaw kɛse, ɛyɛ den sɛ ɔbɛhome, akisikuru, ɔfe, ne akisikuru.
• Mogya mmoroso a ɛba fam ho sɛnkyerɛnne: adwenemhaw, adwenemhaw, ɔtopae, te nka sɛ wayɛ mmerɛw anaasɛ wabrɛ wɔ ɔkwan soronko so.
• Adwene a ɛne sɛ obekum ne ho.
• Nsa, anim, ti, ano, kɔn, anaa nipadua atifi a wɔde keka wɔn ho a wontumi nni so.

Nsunsuanso bɔne a mpɛn pii no ɛnyɛ aniberesɛm, nanso sɛ ɛkɔ so a, ɛsɛ sɛ wobɔ wo duruyɛfo amanneɛ:

• Ano a ɛyɛ nwunu
• Abofono
• Ɔhaw a ɛba wɔ nna mu
• Yafunu a ɛyɛ basaa

Saa nsɛm a wɔahyehyɛ yi nka nsunsuanso bɔne a ebetumi aba nyinaa ho. Sɛ wuhu biribi a ɛyɛ soronko a, bisa wo duruyɛfo.

Ɔkwan bɛn so na ɛsɛ sɛ mede saa aduru yi sie?

Ɛho hia paa nso sɛ wode w’aduru sie yiye.

• Fa sie baabi a mmofra ne afieboa ntumi nkɔ, baabi a wontumi nnya.
• Fa sie wɔ dan mu hyew (a ɛyɛ digrii Celsius 15 kosi 30, digrii Fahrenheit 59 kosi 86).
• Mfa nnuru a ne bere atwam nni dwuma. Tow wɔn gu.

Wobɛyɛ dɛn atow nnuru a wɔmfa nni dwuma a ne bere atwam agu?

• Ade a eye sen biara a ɛsɛ sɛ woyɛ ne sɛ wode eyinom bɛma Nnuru a Wɔsan Fa Dwumadi bi. Wubetumi abisa wo nnurutɔnbea anaa polisifo mmeae yi ho asɛm.
• Sɛ ɛnte saa a, hwɛ nnuru kotoku anaa kratasin no mu hwɛ sɛ ɛsɛ sɛ wɔtow gu nwura mu anaasɛ wɔhohoro gu tiafi mu anaa. Sɛ wunnye nni a, bisa wo duruyɛfo.
• Sɛ wubetumi atow agu nwura mu a, yi aduru no fi ade no mu, fa biribi te sɛ mpataa nwura, dɔte, anaa kɔfe a wɔayam fra mu, fa afrafrade no gu kotoku anaa ade mu, tow ano, na tow gu nwura mu.

Awiei koraa no, kae (Take-Home Message) .

Rasagiline yɛ aduru a ɛho hia ma Parkinson yare, nanso sɛ wɔde di dwuma a, egye ahwɛyiye kɛse.

• Di wo duruyɛfo akwankyerɛ akyi pɛpɛɛpɛ bere nyinaa.
• Ka nnuru afoforo a wonom nyinaa ne nyarewa biara a wowɔ ho asɛm kyerɛ wo duruyɛfo .
• Hwɛ nneɛma bɔne a efi mu ba no yiye. Sɛ wuhu biribi a ɛyɛ soronko a, ka kyerɛ wo duruyɛfo ntɛm ara.
• Kae sɛ woremfa saa aduru yi nka nnuan a tyramine pii wom ho .
• Sɛ wowɔ nsɛmmisa anaa adwenem naayɛ bi a, mma wofɛre sɛ wubebisa wo duruyɛfo anaa nnuruyɛfo.

W’akwahosan ho hia wo paa, enti ɛho hia paa sɛ wobɛhwɛ saa nneɛma yi so.

` Rasagiline, Parkinson Yare, MAOI, nnuru, nsunsuanso bɔne, nnuru a ɛne ne ho di nkitaho, tyramine, aduruyɛ mu afotu, Azilect