Ahobammɔ a egye ntɛmpɛ a ɛba bere a wɔsa kokoram: Momma yensua Tumor Lysis Syndrome ho ade!

Kokoram a wobɛtra ase no yɛ apereperedi ankasa. Ɛwom sɛ ayaresa te sɛ nnuru a wɔde sa yare betumi aboa ma wɔasɛe kokoram nkwammoaa de, nanso ɛtɔ mmere bi a saa ayaresa no betumi de ɔhaw ahorow a wɔnhwɛ kwan aba. Ɛnnɛ, yɛrebɛka tebea bi a egye ntɛmpɛ a ɛsɛ sɛ wɔhwɛ so ntɛm ara na ebetumi de nkwa mpo ato asiane mu ho asɛm . Wɔfrɛ eyi Tumor Lysis Syndrome.

Dɛn ne Tumor Lysis Syndrome? Momma yɛnte ase tiawa.

Sɛ yɛbɛka no tiawa a, Tumor Lysis Syndrome yɛ tebea horow a emu yɛ den kuw bi a ɛba bere a kokoram nkwammoaa pii wuwu prɛko pɛ na saa nkwammoaa no mu nneɛma kɔ mogya no mu no. Fa no sɛ, tebea yi betumi aba wɔ nnɔnhwerew kakraa bi akyi bere a wɔafi kokoram ayaresa ase no. Ebetumi anya nkɔso ntɛmntɛm paa na abɛyɛ tebea a ɛhwehwɛ sɛ wɔsa yare ntɛm ara. Enti, nnuruyɛfo hwɛ eyi yiye bere nyinaa.

Nanso asɛmpa bi wɔ hɔ. Nnuruyɛfo wɔ akwan horow a wɔfa so siw Tumor Lysis Syndrome ano . Wɔyɛ eyi denam onii a ɔwɔ asiane kɛse mu a wohu ne nneɛma a wɔyɛ de tew saa asiane no so no so.

Dɛn na ɛto yɛn nipadua wɔ tebea yi mu?

Sɛ kokoram nkwammoaa nya adwennwen, titiriw fi ayaresa te sɛ nnuru a wɔde sa yare mu a, ɛpaapae. Afei, nnuru ne awuduru a ɛwɔ saa nkwammoaa no mu no boaboa ano mpofirim pii wɔ mogya no mu. Ɔhaw no fi ase bere a yɛn nipadua no ntumi nyi eyinom mfi hɔ ntɛm no. Saa tumor lysis syndrome yi betumi aka yɛn koma, asaabo, ne yɛn ntini titiriw. Ma yɛnhwɛ nea saa nsunsuanso ahorow yi yɛ:

• Hyperuricemia - Eyi kyerɛ sɛ uric acid dodow kɔ soro: Sɛ uric acid a ɛwɔ mogya mu kɔ soro a, ebetumi akɔhyɛ asaabo mu, na ama asaabo no ayɛ adwuma yiye na mpo asaabo no ayɛ adwuma yiye. Fa no sɛ biribi a asiw nsu paipu mu.
• Hyperphosphatemia - kyerɛ sɛ, phosphorus dodow a ɛkɔ soro: Phosphorus dodow a ɛkɔ soro wɔ mogya mu nso siw asaabo no dwumadi kwan.
• Hyperkalemia - Eyi kyerɛ sɛ potassium dodow kɔ soro: Sɛ potassium dodow dɔɔso a, wubetumi anya sɛnkyerɛnne te sɛ akisikuru, ɔfe, ne akisikuru. Ɛnyɛ ɛno nko, na mmom wo koma bɔ betumi asesa, na ama woayɛ basaa, na ebia wo komayare mpo. Eyi yɛ asiane kakra, ɛnte saa?
• Uremia: Eyi ba bere a asaabo no gyae awuduru a efi mogya no mu yiyi mu no. Uremia betumi de ɔhaw a emu yɛ den aba nnompe, ntini, koma, ne mogya ntini mu.
• Hypocalcemia - Calcium dodow a ɛba fam: Calcium dodow a ɛba fam wɔ mogya mu no betumi ama nsakrae aba koma no mu, ntini mu akisikuru, adwene a ɛyɛ basaa, ayɛ mmerɛw ne akwaa a ɛyɛ mmerɛw. Ɛtɔ mmere bi mpo a, owu a efi komayare mu tumi ba.

Ade a ɛho hia sen biara: Tumor Lysis Syndrome ba bere a tebea horow yi mu biako anaa nea ɛboro saa bom no.

So Tumor Lysis Syndrome yɛ ade a egye ntɛmpɛ?

Yiw, koraa! Tumor Lysis Syndrome yɛ aduruyɛ mu tebea a egye ntɛmpɛ a ɛsɛ sɛ wɔsa no ntɛm ara. Enti, ɛho hia paa sɛ yehu eyi.

Hena na obetumi atɔ tebea yi mu?

Ɛnyɛ obiara a wɔma no kokoram ayaresa na onya Tumor Lysis Syndrome. Sɛ worenya kokoram ayaresa a, ɛbɛyɛ papa sɛ wubebisa wo duruyɛfo no eyi ho asɛm. Mpɛn pii no, nnipa a wɔde nnuru a wɔde sa kokoram ahorow a edidi so yi di dwuma no wɔ asiane kɛse mu sɛ wobenya saa tebea yi:

• Lymphocytic Leukemia a Ɛyɛ Hu a Ɛyɛ Hu
• Ntini a Ɛnyɛ Hodgkin Ntini a Ɛyɛ Hu, te sɛ Burkitt Lymphoma ne Diffuse Large B-cell Lymphoma
• Leukemia a Ɛyɛ Hu (AML) .
• B-cell Acute Lymphoblastic Leukemia (ALL) .
• Nkwammoaa Nketewa Ahurututu Mu Kokoram

Afei nso, kokoram ahorow afoforo bi wɔ hɔ a sɛ wɔsa a, asiane a ɛwɔ hɔ sɛ wobenya saa tebea yi sua kakra. Nanso ɛnyɛ nea ayera koraa. Nhwɛso ahorow:

• Anaplastic Large Cell Lymphoma - Eyi yɛ kokoram a ɛntaa nsi, a ɛkɔ so brɛoo wɔ nipadua no mu tumi a ɛko tia nyarewa no mu.
• Leukemia a Ɛma Ntini Mu Ntini a Enni Nni Hɔ (CLL) .
• Ntini mu ntini mu yare
• Nufu mu Kokoram
• Nkwammoaa a Ɛyɛ Dwo Sarcoma
• Medulloblastoma a ɛwɔ nipadua no mu
• Merkel Nkwammoaa mu Kokoram

Dɛn ne nneɛma afoforo a ɛde Tumor Lysis Syndrome ba?

Nnuruyɛfo nim sɛ nnipa binom wɔ asiane kɛse mu sɛ wobenya saa yare yi. Wɔyɛ ahwɛyiye titiriw ansa na wɔde nnuru a wɔde sa yare ama nnipa a wɔte saa. Nneɛma bi a ɛma asiane no yɛ kɛse ni:

• Mogya mu nkwammoaa fitaa dodow a ɛkɔ soro yiye a wobenya.
• Uric acid dodow a ɛwɔ mogya no mu no dɔɔso dedaw.
• Asaabo mu haw ahorow a wowɔ.
• Nsu a ɛwɔ nipadua mu a ɛso tew (Dehydration).
• Kokoram a obi wɔ wɔ bere a emu yɛ den mu (Kokoram a ɛba akyiri yi).
• Sɛ obi wɔ akisikuru akɛse.

So tebea yi betumi aba a wɔmfa nnuru a wɔde sa yare nni dwuma?

Yiw, nanso ɛntaa nsi koraa . Sɛ ɛba saa a, nnuruyɛfo frɛ no Spontaneous Tumor Lysis Syndrome.

Dɛn ne Tumor Lysis Syndrome ho sɛnkyerɛnne ahorow?

Mpɛn pii no, saa sɛnkyerɛnne ahorow yi da adi wɔ nnɔnhwerew 12 kosi 72 akyi bere a wɔafi nnuru a wɔde sa yare ase no. Nea wɔyɛ ni:

• Akisikuru ne ɔfe.
• Ayamtuo.
• Nsakrae a ɛba nsu dodow a wode fa mu (ebetumi akɔ soro anaasɛ ɛbɛtew).
• Mmerewa ne Ɔbrɛ.
• Mogya a ɛwɔ nsu mu (Hematuria).
• Epileptic tebea horow, kyerɛ sɛ, akisikuru.
• Ntini mu Akisikuru.
• Syncope a ɛma obi ho kyere no.
• Koma a ɛbɔ a ɛnteɛ.
• Mogya mmoroso a ɛba fam (Hypotension).
• Nkwaa mu Ɛyaw.

Sɛ wuhu saa sɛnkyerɛnne ahorow yi mu biako anaa nea ɛboro saa bere a woreyɛ kokoram ayaresa a, ɛsɛ sɛ wobɔ oduruyɛfo amanneɛ ntɛm ara.

Dɛn nti na Tumor Lysis Syndrome ba?

Sɛ yɛbɛka no tiawa a, tebea yi ba bere a kokoram ayaresa ma kokoram nkwammoaa pii wuwu mpofirim na ɛyɛ ntɛmntɛm no. Nneɛma a ɛwɔ nkwammoaa a ɛrewuwu no mu (te sɛ potassium, phosphorus, ne uric acid) boaboa ano mpofirim wɔ mogya no mu.

Mpɛn pii no, yɛn asaabo na ɛyi nneɛma a yɛmpɛ yi fi mu. Nanso, sɛ nkwammoaa dodow bi wuwu prɛko pɛ a, asaabo no ntumi nyɛ adwuma yi. Ɛte sɛ nea nsu a ɛkɔ nsu mu no siw bere a nwura pii ba prɛko pɛ no. Afei saa awuduru yi fi ase boaboa ano wɔ nipadua no mu.

Ɔkwan bɛn so na nnuruyɛfo hu saa tebea yi?

Nnuruyɛfo adwene titiriw ne sɛ wobesiw Tumor Lysis Syndrome ano. Nea ɛbɛyɛ na wɔayɛ eyi no, wɔbɛyɛ mogya ne nsu mu nhwehwɛmu daa de ahwɛ ahu sɛ w’asaabo reyɛ adwuma yiye na wɔreyi awuduru afi wo nipadua mu.

Dɛn ne ayaresa ahorow a wɔde sa Tumor Lysis Syndrome?

Mmɔden a edi kan a nnuruyɛfo bɔ ne sɛ wobesiw eyi ano. Wɔyɛ eyi denam wɔn a asiane kɛse wom a wohu na wɔyɛ ahwɛyiye titiriw ma wɔn no so. Nanso, sɛ tebea no ba a, wofi ase sa yare ntɛm ara.

Nneɛma a ɛsɛ sɛ woyɛ de siw ano:

• Nsu a Wɔde Fa Ntini Mu (IV): Eyi boa ma nsu a ɛwɔ nipadua no mu no kɔ so yɛ papa, ɛma obi tow nsu, na ɛboa ma awuduru fi nipadua no mu ntɛmntɛm.
• Nnuru a wɔde ma a esiw uric acid ahwehwɛ a ɛbɛkɔ asaabo mu no ano: Nnuru bi wɔ hɔ a ɛboa ma wosiw uric acid dodow ano.

Sɛ tebea no ba a, ayaresa:

• Nnuru a ɛma nsu fi nipadua no mu a wɔde ma: Eyi boa ma awuduru fi nipadua no mu ntɛmntɛm.
• GLISH: Nnuru a wɔde yi potassium ne phosphorus a ɛboro so a wɔde ma.
• Nnuru a ɛma uric acid ahwehwɛ a ayɛ wɔ asaabo mu no ma.
• Dialysis: Sɛ w’asaabo ntumi nyɛ adwuma yiye a, ebia ebehia sɛ woyɛ dialysis na ama awuduru afi wo mogya mu. Eyi te sɛ nea woreyɛ w’asaabo adwuma no wɔ ɔkwan a wɔde nsa ayɛ so.

So wobetumi asa Tumor Lysis Syndrome yare no?

Yiw, koraa! Ɛkame ayɛ sɛ nnipa a wonya saa tebea yi mu ɔha biara mu 90 ho tɔ wɔn. Ade a ɛho hia sen biara ne sɛ wubehu no ntɛm na woafi ayaresa ase ntɛm.

Dɛn na ɛba bere a wɔasa tebea yi akyi?

Tumor Lysis Syndrome betumi asɛe w’asaabo kakra. Enti, sɛ wowɔ saa tebea yi a, ɛho hia paa sɛ wubisa wo duruyɛfo sɛ wuhia ayaresa foforo anaa ɔhwɛ soronko kosi sɛ w’asaabo bɛsan ayɛ yiye anaa.

Kokoram ayaresa renya nkɔso da biara da, na ɛma yetumi sɛe kokoram nkwammoaa ntɛmntɛm. Nanso, ɛtɔ mmere bi a, sɛ saa nkwammoaa yi wuwu a, nnuru ne awuduru a woyi fi mu no betumi de tebea bi a ɛyɛ hu a wɔfrɛ no Tumor Lysis Syndrome aba. Eyi betumi anya koma ne asaabo so nkɛntɛnso kɛse.

Awiei koraa no, nea ɛsɛ sɛ wokae (Take-Home Message) .

Kokoram ayaresa yɛ asɛnnennen. Saa bere yi mu no, ɛho hia sɛ wohu nneɛma a egye ntɛmpɛ te sɛ Tumor Lysis Syndrome. Sɛ woreyɛ kokoram ayaresa a, hwɛ hu sɛ wubebisa wo duruyɛfo sɛ ebia wowɔ asiane mu sɛ wubenya saa tebea yi anaa. Wɔbɛkyerɛkyerɛ asiane ahorow mu akyerɛ wo na wɔayɛ nea wobetumi biara de asiw tebea yi ano anaasɛ wɔbɛsa sɛ ɛba a. Mmu w’ani ngu yare no ho sɛnkyerɛnne biara so, na sɛ wuhu biribi a ɛyɛ soronko a, ka kyerɛ oduruyɛfo ntɛm ara. W’akwahosan a wobɛhwɛ so yiye ne ade a ɛho hia sen biara!

` Tumor lysis syndrome, kokoram ayaresa, nnuru a wɔde sa yare, asaabo mu yare, hyperkalemia, hyperuricemia, aduruyɛ mu ntɛmpɛ