Do you also experience uncontrollable daytime sleepiness? Do you sometimes feel like you are about to faint and fall to the ground when you suddenly laugh or get angry? In medical terms, we call this condition Narcolepsy. So, a special medicine that is prescribed to treat this condition is called Pitolisant. You may have bought it from your doctor under the brand name Wakix. Today, we will talk about this medicine in a simple way that you can understand.
Simply put, what is Pitolisant?
This is a medicine that is given to treat a condition called `Narcolepsy`. This mainly helps to reduce excessive sleepiness during the day. Also, this medicine helps to control a condition called `(Cataplexy)` where the muscles of the body suddenly lose their strength. This medicine helps to keep you awake during the day by controlling certain chemicals in the brain. This can also improve your nighttime sleep to some extent.
Things you need to tell your doctor before starting this medication
Before giving you this medicine, your doctor will need to know your complete health history. This is because it can be dangerous to use this medicine with certain medical conditions. Therefore, be sure to tell your doctor if you have any of the following conditions:
- Heart disease: If you have any heart disease.
- Irregular heartbeat: If you have been previously diagnosed with an irregular heartbeat.
- Kidney disease: If there is any problem with the kidneys.
- Liver disease: If you have any problems with your liver, such as cirrhosis.
- Low potassium or magnesium levels: If you have previously been reported to have low potassium or magnesium levels in your blood.
- Allergies: If you have an allergy to `Pitolisant`, any other medicine, food, or dye.
- Pregnancy: If you are pregnant or hoping to become pregnant.
- If you are a breastfeeding mother: If you are a mother who is breastfeeding a child.
Don't hide this information. It's very important to discuss these things with your doctor for your safety.
How exactly do you use this medicine?
This medicine should be used exactly as your doctor advises.
- Take this pill with a glass of water. It is best to take it at the same time every day.
- You can take it before or after meals, but if you feel like you're having an upset stomach, it's best to take it with food.
- Continue using this medicine until your doctor tells you to stop.Don't stop suddenly, as you please.
- If given to children: This medicine is sometimes prescribed to children over 6 years of age. But it is done with great caution. If giving this to a child, follow the doctor's instructions exactly.
What do you do if you take too much medicine?
If you think you have taken more medicine than you think, go to the nearest hospital ETU (Emergency Treatment Unit) without delay . Or call the National Poisons Information Centre at the Colombo National Hospital for advice.
What if I miss a dose of medication?
If you forget to take a dose, skip it. Take the next dose at your regular time. Never take two pills at once to make up for a missed dose.
Other medicines that should not be used with Pitolisant and that may cause problems
This is a very important part. `Pitolisant` can interact with some other medications. This can cause dangerous side effects. Therefore, if you are using any other medications, tell your doctor about all of them. This includes vitamins, traditional medicines, and even herbal products.
| Types of medicines and their effects | |
|---|---|
| Never use Pitolisant with this medicine. | |
Some medications used for heart disease. For example:
| |
| If you are taking Pitolisant with these medications, inform your doctor. | |
| Drug category | Examples |
| Medicines for allergies, coughs, and colds (Antihistamines) | Eg: Piriton, Cetirizine |
| Medication for irregular heartbeat | Amiodarone, such as Quinidine |
| Medications for mental illness (depression, anxiety) | Various types of medicines |
| Medicine for migraine (Fit) | Carbamazepine, Phenytoin, etc. |
| Types of hormones | Estrogen, Progestin hormones (found in birth control pills) |
| Other | Cyclosporine, Rifampin, St. John's wort (herbal extract) |
Special points to be aware of when taking the medicine
- Medical Checkups: Continue to go to the clinics as prescribed by your doctor to check your condition. If your symptoms do not improve or worsen, tell your doctor.
- Dry mouth: This medication may cause dry mouth. This can be controlled by chewing sugar-free gum and drinking plenty of water. However, if this problem persists or is severe, tell your doctor.
- Special information about birth control: This is very important. If you are a woman using hormonal birth control pills (containing ``Estrogen`` and ``Progestin``), the effectiveness of those birth control pills may be significantly reduced when you take ``Pitolisant``. Simply put, the ability of those pills to prevent pregnancy is reduced. Therefore, it is imperative to discuss with your doctor about using an additional form of birth control, such as a condom , while taking this medication and for a period of time after stopping it.
Side effects that may occur with this medicine
Like any medicine, Pitolisant can cause some side effects. Some are dangerous, some are common.
| Type of side effect | Symptoms |
|---|---|
| Side effects that should be reported to the doctor immediately | |
| Allergic Reactions | Skin rash, itching, swelling of the face, lips, tongue or throat. |
| Heart Rhythm Changes | Feeling like your heart is beating fast or irregularly, dizziness, fainting, chest pain, and difficulty breathing. |
| Side effects that are usually not dangerous, but should be reported to the doctor if they persist | |
| Psychological effects | Anxiety, restlessness. |
| Headache | Common headache. |
| Nausea | Feeling like vomiting. |
| Sleep problems | Inability to sleep at night. |
This list does not include all possible side effects. If you notice anything unusual, talk to your doctor.
How do you store and dispose of medication safely?
- Keep away from children and pets.
- Store at room temperature (between 20-25 degrees Celsius). Protect from excessive heat and moisture.
- Throw away expired medications . Don't use them.
- When disposing of medications, ask your doctor if you are unsure whether to throw them in the trash or flush them down the toilet. If you are disposing of them in the trash, remove the pills from the bottle, mix them with something like used tea leaves or soil, put them in a bag, and seal it tightly. This will help prevent other people or animals from eating them.
Take-Home Message
- `Pitolisant` is a special medicine given for excessive daytime sleepiness and `Narcolepsy`.
- Before starting this medication, tell your doctor about all your medical conditions (especially heart, kidney, and liver disease).
- Tell your doctor about all other medications you are taking. Some medications may interact with this one.
- If you experience symptoms such as rapid heartbeat and dizziness, seek medical advice immediately.
- Most importantly: If you are taking birth control pills, talk to your doctor about using an additional form of birth control (e.g. condoms) while taking this medication, as the effectiveness of birth control pills may be reduced.











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