Has your mother, father, or yourself been prescribed this medicine by your doctor for high blood pressure or swelling? Sometimes, the name of this medicine can make you a little nervous. But when you know the details, that's not the case. So, today we'll talk about the things you need to know about this medicine in simple terms.
What is this medicine?
Simply put, this is a combination of two medications. That is, Spironolactone and Hydrochlorothiazide are both contained in one pill. This medication is mainly used to control high blood pressure.
In addition, it is also used to reduce swelling in areas such as the legs and arms due to fluid retention in the body due to heart disease, kidney disease, or liver disease.
This belongs to a class of drugs called diuretics. This means that this medicine helps your kidneys to remove excess water and salt from your body through urine. This reduces the pressure in your blood vessels, which helps control blood pressure and reduces swelling.
Things you need to tell your doctor before starting medication
Before your doctor prescribes this medicine, he or she will need to know your complete medical history. Therefore, if you have any of the following conditions, it is important to tell your doctor :
- If you have diabetes.
- If you have an immune system disease, for example, a condition like lupus.
- If you have kidney disease or liver disease.
- If you have previously had an allergy to Spironolactone, Hydrochlorothiazide, sulfa-containing medications, other medications, foods, or preservatives.
- If you are pregnant, or trying to get pregnant.
- If you are a breastfeeding mother.
Based on this information, the doctor will determine the treatment that is most suitable for you.
How should I use this medicine?
The way to use this is very simple.
- Take this pill with water, at the same time every day , exactly as prescribed by your doctor.
- You can take this before or after a meal, but if you feel like you have an upset stomach, it's better to take it with food.
- The most important thing is that you should continue taking this medicine until your doctor tells you to stop. Don't stop suddenly, even if you feel better.
What if I miss a dose of medication?
If you suddenly forget to take a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the scheduled time.Never take a double dose.
What if I take too much medicine?
If you suspect you have taken too much of this medicine, go to a hospital Emergency Department (ETU) immediately. Or call the National Poisons Information Centre at the Colombo National Hospital .
Important: This medicine has been prescribed for you only. Never share your medicine with others, even if they have the same symptoms as you.
Other things that may interact with this medicine
Some medications can cause problems when taken together with this medicine. Therefore, it is very important to inform your doctor about all medications you are taking.
| Drug type | Description |
|---|---|
| Medicines that should not be taken with this medicine | |
| Cidofovir | A medicine for viral infections. |
| Eplerenone | Another medication for high blood pressure and heart disease. |
| Tranylcypromine | A medicine for depression. |
| Other medications that may interact with this medicine | |
| Aspirin and NSAIDs | Painkillers such as Ibuprofen and Naproxen. |
| Other high blood pressure medications | Eg: Benazepril, Lisinopril, Losartan, Valsartan |
| Medications that prevent blood clotting | Ex: Heparin, Enoxaparin |
| Other medications | Cholestyramine, Cyclosporine, Digoxin, Lithium, muscle relaxants for surgery, Potassium supplements, Steroids such as Prednisone, Trimethoprim. |
This list may not include everything, so be sure to tell your doctor about every medication, vitamin, and traditional medicine you are taking.
Things to be careful about when taking medication
- See your doctor regularly: Go to your doctor's appointments to see how you are doing.
- Pay attention to your blood pressure: Measure your blood pressure as your doctor tells you. Learn what your blood pressure should be and when you should call your doctor if it is high.
- Be careful of dehydration: This medicine can cause dehydration because it dehydrates your body. Ask your doctor how much water you should drink each day. Tell your doctor if you have severe diarrhea, vomiting, or are sweating a lot.
- Dizziness and drowsiness: You may feel drowsy or dizzy. So avoid driving or operating machinery until you know how this medicine affects you. Especially if you are elderly, do not stand up or sit up suddenly. Do these things slowly.
- No alcohol: Drinking alcohol can interfere with the effectiveness of this medicine. Therefore, avoid alcohol completely.
- Be careful with the sun: This medicine may make your skin sensitive to sunlight. So be careful with the strong sun. If you go out in the sun, wear clothes that cover your body well and use sunscreen.
What side effects might I experience?
Like any medicine, this can cause side effects in some people, but not everyone gets them.
| Side effect | Description |
|---|---|
| Side effects that you should report to your doctor immediately | |
| Allergic reactions | Skin rash, itching, swelling of the face, lips, tongue. |
| Dehydration | Increased thirst, dry mouth, fainting, dark yellow or brown urine. |
| Gout | Severe pain, redness, and swelling, especially in joints such as the big toe. |
| Changes in potassium levels | Elevated levels: Muscle weakness, irregular heartbeat. Low levels: muscle pain, unusual weakness, constipation. |
| Effect on the kidneys | Decreased urine output, swelling of the ankles, hands, and feet. |
| Reduction in high blood pressure | Dizziness, fainting, blurred vision. |
| Eye problems | Sudden eye pain, blurred vision, seeing rings around lights. |
| Side effects that should be reported to the doctor if they persist or are bothersome | |
Breast pain or tenderness, changes in sexual desire, drowsiness, headache, irregular menstrual cycles, development of breast tissue in men, stomach upset. | |
Take-Home Message
- Always take this medicine exactly as prescribed by your doctor, in the correct dosage, and at the correct time.
- Even if you think you're doing well, don't stop taking the medication without your doctor's advice.
- Tell your doctor about any other medications, vitamins, or traditional medicine you are taking.
- Be aware of dehydration and dizziness while taking the medication. Drink plenty of water.
- If a serious side effect occurs (e.g. severe allergy, difficulty breathing), seek medical advice immediately.
- If you have any questions about this medication, ask your doctor first, not someone else, to clear up any doubts.











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