Ðe wò ŋutilã ƒe ametakpɔnuwo gbɔdzɔa? Mina míasrɔ̃ nu tso agranulocytosis ŋu.

Ðe dzamezã kple asrã dzea dziwò zi geɖe eye nèsena le ɖokuiwò me be yele dɔ lém veviea? Ɣeaɖewoɣi la, dɔléle sue aɖe gɔ̃ hã ate ŋu ava zu nu sesẽ eye wòaxɔ ɣeyiɣi didi hafi wòahaya? Nusi koŋ gbɔ esia tso ate ŋu anye gbɔdzɔgbɔdzɔ le wò ŋutilã ƒe dɔlélenutsiŋutete, si nye asrafoha si kpɔa mía ta tso dɔlélewo me. Egbea míele nu ƒom tso nɔnɔme aɖe si ŋu woate ŋu ake ɖi le le ɣeyiɣi mawo tɔgbe me, si ate ŋu anye afɔku vie, gake woate ŋu adae ŋu.

Kpuie ko la, nukae nye Agranulocytosis?

Agranulocytosis (woyɔnae be: "a-gra-nu-lo-cy-to-sis") nye nɔnɔme si dea ame ƒe agbe afɔku me si me neutrophils, si nye ʋumenugbagbevi ɣi ƒomevi aɖe, ƒe xexlẽme dzi ɖena kpɔtɔna ŋutɔ le míaƒe ʋu me.

Tsɔe be míaƒe ŋutilã le abe dukɔ ene. Ekema ʋumenugbagbevi ɣiwoe nye asrafoha si kpɔa dukɔ ma ta. Asrafoha vovovowo le asrafoha sia me. Le wo dome la , neutrophils nye commando ƒe ƒuƒoƒo tɔxɛ aɖe si yia ɖadzea dɔlékuiwo dzi ne wonya kpɔ wo ko . Eyata ne commando siawo ƒe xexlẽme dzi ɖe kpɔtɔ ŋutɔ la, dɔlékui sue aɖe si tso egodo gɔ̃ hã ate ŋu adze míaƒe ŋutilã dzi bɔbɔe eye wòana míadze dɔ.

Nɔnɔme sia ate ŋu ana nàxɔ dɔlékui sesẽwo bɔbɔe wu, tso dɔlékui siwo megblẽa nu le mía ŋu zi geɖe o gɔ̃ hã gbɔ.

Eyata vovototo kae le Neutropenia kple Agranulocytosis dome?

Ðewohĩ èse nya si nye neutropenia hã kpɔ. Togbɔ be eve siawo ɖi wo nɔewo hã la, vovototo vi aɖe le wo dome.

• Neutropenia: Nɔnɔme ɖesiaɖe si me neutrophils ƒe xexlẽme le ʋɛ wu alesi wòle.
• Agranulocytosis: Esiae nye ʋumenugbagbeviɣidɔ si nu sẽ wu eye afɔku le eme wu.

Kpuie ko la, ne neutrophil ƒe agbɔsɔsɔ ɖiɖi akpa la, míeyɔnae be Agranulocytosis.

Susu kawoe hea nɔnɔme sia vɛ?

Agranulocytosis ate ŋu adzɔ le mɔ vevi eve nu.

1. Agranulocytosis si ƒe domenyinyi: Esia tsoa domenyiŋusẽfianu siwo wɔa neutrophils ƒe gbɔdzɔgbɔdzɔ gbɔ. Esia mebɔ kura o eye wòbɔ ɖe vidzĩ suewo kple ɖevi suewo me wu.

2. Acquired Agranulocytosis: Esiae nye ƒomevi si bɔ wu. Nu vovovowo ate ŋu ahe esia vɛ. Gake le nɔnɔme siwo ade 70% me la, enye atike aɖewo siwo míenona ƒe nugbegblẽ le ame ŋu. Esia ƒomevi bɔ ɖe ame tsitsiwo dome wu.

Nu vevi siwo gbɔ agranulocytosis si kplɔe ɖo tsona

• Atike aɖewo: Nɔnɔme sia ate ŋu atso atikewo abe dɔlékuiwutike aɖewo, tagbɔdɔléle ƒe atikewo (e.g. clozapine), kple atike siwo wozãna na thyroid dɔlélewo (e.g. methimazole) gbɔ.
• Atikewɔmɔnu: Ne kansa lãmenugbagbeviwo tsrɔ̃ la, neutrophils, siwo nye lãmenugbagbevi siwo le lãmesẽ me siwo mãna kabakaba hã ate ŋu agblẽ.
• Dɔlélenutsiŋutete ƒe dɔlélewo: Esia nye ne míaƒe ŋutilã ŋutɔ ƒe dɔlélenutsiŋutete wɔa nu gbegblẽ eye wòdze eya ŋutɔ ƒe lãmenugbagbevi siwo le lãmesẽ me dzi. Kpɔɖeŋu aɖewoe nye dɔlélewo abe Lupus kple Rheumatoid Arthritis ene.
• Ƒumeŋuɖui ƒe Dɔlélewo: Ƒumeŋuɖui ye nye dɔwɔƒe si wɔa míaƒe ʋumenugbagbeviwo katã. Eyata dɔléle siwo gblẽa nu le dɔwɔƒe sia ŋu, abe kansa abe ʋumenugbagbeviɣidɔ alo ʋusɔgbɔdɔ si woyɔna be aplastic anemia ene, ate ŋu agblẽ nu le neutrophil ƒe wɔwɔme ŋu.
• Dɔlékui aɖewo: Dɔlékui sesẽwo abe asrã kple yɔmekpe ene hã ate ŋu atso nɔnɔme sia gbɔ.
• Nunyiame ƒe veve: Afɔku sia nɔa nunyiamewo abe vitamin B12 kple folate ene ƒe anyimanɔmanɔ ɣeyiɣi didi hã me.
• Atike siwo me aɖi le: Atike siwo me aɖi le abe lead alo mercury ene ɖuɖu.

Nukae nye agranulocytosis ƒe dzesiwo?

Esi neutrophil ƒe xexlẽme mede ame dzi o ta la, dɔléle sia ƒe dzesi vevitɔwoe nye dɔlékui aɖe . Esiawo ate ŋu ado kpata alo ava do vivivi.

Nu vevi siwo woate ŋu akpɔe nye esiawo:

• Vuvɔ sesẽ, ʋuʋu, kple asrã .
• Dzi ƒe tsotso kple gbɔgbɔ ƒe tsotso ƒe dzidziɖedzi.
• Ðeɖiteameŋu kple gbɔdzɔgbɔdzɔ ƒe seselelãme le ŋutilã si menɔ anyi tsã o .
• Kɔmeve, aɖu siwo vuvu eye ʋu le dodom.
• Nu mimi sesẽ le nu me kple ŋɔti me abi ta .
• Ʋu ƒe sisi kpata (ʋusɔgbɔdɔ) si wɔnɛ be wòsena le eɖokui me be yetsi dzodzodzoe eye taɖuame.

Aleke ɖɔkta awɔ anya dɔléle siae?

Ne dzesi siwo míeyɔ ɖe etame dometɔ aɖe le ŋuwò, vevietɔ ne dɔlékuiwo le ŋuwò enuenu la, ɖɔkta aɖe ado wò kpɔ. Dodokpɔ vevitɔ kekeake si woawɔ atsɔ anya ne dɔléle sia le ŋuwòe nye ʋudodo blibo (CBC) . Ɣeaɖewoɣi la, míeyɔa esia hã be ʋudodo blibo (FBC).

Dodokpɔ sia dzidzea neutrophils ƒe xexlẽme tututu le wò ʋu me. Ne neutrophil ƒe xexlẽme mede 100 le microlitre ɖeka me o la, wokpɔnɛ be Agranulocytosis ye.

Tsɔ kpe ɖe eŋu la, ɖɔkta ate ŋu aɖe gbe be woagawɔ dodokpɔ bubuwo atsɔ anya nusi gbɔ wòtso.

• Ƒumeŋuɖui Ŋuti Nusɔsrɔ̃: Wowɔa dodokpɔ sia be woakpɔe ɖa be kuxi aɖe le ƒumeŋuɖui, si nye dɔwɔƒe si wɔa ʋumenugbagbeviwo ŋu hã.
• Domenyiŋusẽfianu Dodokpɔ: Ne ɖikeke aɖe li be dɔléle si wodzinae nye esia la, woate ŋu aɖo wò ɖe dodokpɔ sia wɔwɔ me.

Nukawoe nye agranulocytosis ƒe atikewo?

Togbɔ be esia nye nɔnɔme si me afɔku le hã la, nya nyuiae nye be atike nyuiwo li na esia. Atikewɔwɔa nɔ te ɖe nusi le nɔnɔmea hem vɛ dzi.

• Atike Siwo Hea Wòa Dzudzɔ: Ne atike aɖe si nèzãnae nye nusi gbɔ nɔnɔme sia tso la, nu gbãtɔ kple vevitɔ kekeake si nàwɔe nye be nàdzudzɔ atike ma nono. Ke hã, mègadzudzɔ wò atikewo nono le ɖokuiwò si gbeɖe o. Kpɔ egbɔ be yeƒo nu kple wò ɖɔkta eye nàwɔ ɖe eƒe mɔfiamewo dzi be nàwɔe dedie.

• Dɔlékuiwutikewo: Ne dɔlékui aɖe le wò ŋutilã me xoxo la, wò ɖɔkta aŋlɔ dɔlékuiwutike sesẽwo na wò be wòatsɔ awɔ avu kplii.

• G-CSF ƒe atikewo dodo: Woyɔa esiawo be Granulocyte Colony-Stimulating Factor (G-CSF). Atike siawo doa ŋusẽ ƒumeŋuɖui eye wokpena ɖe eŋu wòwɔa neutrophil cells kabakaba wu.

• Dɔlélenutsiŋutete ƒe dɔlékuiwutikewo: Ne dɔléle si dɔlélenutsiŋutete ŋutɔ gbɔe wòtso la, woate ŋu ana atikewo abe prednisone ene be woatsɔ ana dɔlélenutsiŋutete si wɔa dɔ fũu akpa la nafa.

• Ƒumeŋuɖui Dodo: Ne dɔdamɔnu bubuwo medze edzi o la, woate ŋu awɔ ƒumeŋuɖui dodo na ame si le lãmesẽ me abe mɔnu mamlɛtɔ ene.

Aleke mawɔ akpɔ ɖokuinye ta tso dɔlékuiwo me le atikewɔwɔ me?

Ele vevie ŋutɔ be nàƒo asa na dɔlékuiwo xɔxɔ esime nèle atike wɔm na amesi ŋu dɔléle sia le.

• Klɔ asi nyuie kple adzalẽ ɣesiaɣi.
• Ðe teƒe siwo amewo sɔ gbɔ ɖo yiyi dzi kpɔtɔ alesi nàte ŋui.
• Do motsyɔnu ne èle dodom.
• Nuɖuɖu siwo woɖa nyuie, siwo le dzadzɛ koe ɖu.

Ðe wòanya wɔ be woahaya tso nɔnɔme sia me bliboea?

Ẽ, zi geɖe la, anya wɔ. Ɣeyiɣi si woatsɔ ahaya la nɔ te ɖe nusi gbɔ wòtso dzi.

Ne atike aɖe gbɔe wòtso la, zi geɖe la, neutrophil ƒe xexlẽme gatrɔna yia nɔnɔme si sɔ me le kwasiɖa 1 va ɖo 3 me le atikeawo zazã dzudzɔ vɔ megbe.

Ne wokpɔ dɔléle sia dze sii hedae kaba la, woate ŋu aɖu dɔléle sia dzi keŋkeŋ. Gake ne womewɔ atike nɛ o la, ate ŋu ahe dɔlékui sesẽwo kple nɔnɔme siwo ate ŋu ade ame ƒe agbe afɔku me abe dɔlékuiwutikewo ene vɛ . Amesiwo xɔ wu ƒe 65 kple amesiwo ŋu dzi, ayiku, alo lãkusidɔ bubuwo le la ate ŋu adze kuxiwo gɔme.