Ðe ‘Blast Cells’ le wò Ʋu Ŋuti Nyatakaka mea? Mina míaƒo nu tso esia ŋu ko (Blast Cells) .

Èkpɔ nya ‘Blasts’ kpɔ ne èle wò ʋu ŋuti nyatakaka kpɔma? Enye nusi sɔ be nàvɔ̃ vie eye nàdi be yeanya nu tso eŋu ne èkpɔe. Elabena le nyateƒe me la, nya sia si míenya o la gblɔ nya geɖe tso míaƒe lãmesẽ ŋu. Eyata egbea, mina míaƒo nu tso nusiwo nye Blast Cell siawo, alesi wole vevie na míaƒe ŋutilã, kple nusi woƒe xexlẽme si dzi ɖe edzi ɖe fia ŋu. Mègatsi dzi o, mina míase nya sia gɔme bɔbɔe.

Nukae nye Blast Cells le nya bɔbɔewo me?

Kpuie ko la, blast cells nye "vidzĩ ƒe lãmenugbagbeviwo" alo lãmenugbagbevi siwo metsi o. Abe vidzĩ ene. Esiawoe nye lãmenugbagbevi siwo tsina emegbe, si fia be wotsina, eye wozua lãmenugbagbevi vovovo siwo míaƒe ŋutilã hiã. Gake ne wò dodokpɔxɔ ƒe nyatakaka yɔ "blasts" la, anɔ eme godoo be efia ʋumenugbagbevi siwo metsi o . Ʋumenugbagbeviɣidɔŋutinunyalawo kple kansadɔdalawo léa ŋku ɖe lãmenugbagbevi siawo siwo le wò ʋu me ƒe xexlẽme ŋu be yewoaƒo nya ta tso dɔléle vovovo siwo do ƒome kple ʋu ŋu.

Vovototo kae le Stem Cells kple Blast Cells dome?

Esia hã nye nusi tɔtɔa ame geɖe. Bu lãmenugbagbeviwo be wonye "lãmenugbagbevi gbãtɔ" si dzea nusianu gɔme. Ele abe anyikpe gbadzɛ aɖe ene. Míate ŋu awɔ nusianu tso anyikpe ma me, abe ze, kplu, nusianu ene. Aleae lãmenugbagbeviwo le. Woate ŋu ava zu lãmenugbagbevi ƒomevi ɖesiaɖe.

Blast cells ye nye afɔɖeɖe si kplɔe ɖo le lãmenugbagbevi siawo ƒe tsitsi me. Fifia míedze ze aɖe wɔwɔ gɔme kple anyikpe ma, eye wòle nɔnɔme xɔm. Fifia míagate ŋu awɔe wòazu kplu ake o. Eyata, blast cell nye lãmenugbagbevi si dze mɔzɔzɔ aɖe koŋ dzi yiyi gɔme. Eyae nye be etso nya me be yeazu ʋumenugbagbevi dzĩ, ʋumenugbagbevi ɣi, alo ʋumenugbagbevi dzĩ. Esia tae wogayɔa blast cells be "precursor cells."

Dɔ si blast cells wɔna le míaƒe ŋutilã me kple afisi wowɔa wo le

Ʋu ƒe wɔwɔme le míaƒe ŋutilã me ƒe akpa ɖeka koe lãmenugbagbevi siwo le dzo dam nye. Míeyɔa ʋu ƒe wɔwɔme sia be `Hematopoiesis`. Esia dzɔna le míaƒe ƒumeŋuɖui me koŋ . Ƒumeŋuɖui le abe míaƒe ŋutilã ƒe ʋuwɔƒe ene.

Le dɔwɔƒe sia me la, lãmenugbagbevi vevitɔ si woyɔna be `Hematopoietic Stem Cell (HSC)` naa blast cell ƒomevi vevi eve:

• Myeloblast: Blast cell siawo tsina emegbe zua ʋumenugbagbevi dzĩwo (siwo tsɔa oxygen), ʋumenugbagbevi ɣi ƒomevi aɖewo (granulocytes - siwo wɔa avu kple dɔlékuiwo), kple ʋumenugbagbevi dzĩwo (siwo kpena ɖe ʋu ŋu be wòaxe).
• Lãmetsiŋusẽ: Lãmenugbagbevi siawo va zua ʋumenugbagbevi dzĩwo, si nye ʋumenugbagbevi ɣi ƒomevi vevi bubu (si nye dɔlélenutsiŋutete ƒe akpa vevi aɖe).

Nukae hea blast cells ƒe dzidziɖedzi vɛ?

Ele be blast cells nanye lãmenugbagbevi siwo katã le ame si le lãmesẽ me ƒe ƒumeŋuɖui me ƒe xexlẽme si mede 5% o. Azɔ hã, mele be lãmenugbagbevi siwo wotsɔna gbãa nu nanɔ ame si le lãmesẽ me ƒe ʋu me o.

Ne blast cells ƒe xexlẽme dzi ɖe edzi le wò ƒumeŋuɖui alo ʋu me la, ate ŋu anye ʋumenugbagbeviɣidɔ abe ʋumenugbagbeviɣidɔ ene ƒe dzesi, vevietɔ ne lãmenugbagbevi siawo dze abe ɖe womesɔ o ene ne wokpɔ wo le nusuekpɔmɔ̃ me.

Àte ŋu ase esia gɔme nyuie wu tso kplɔ̃ si le ete la dzi.

Ðe blast cells ate ŋu adzi ɖe edzi evɔ womahe kansa vɛ oa?

Ẽ, àte ŋui. Esia le vevie ŋutɔ. Menye ɣesiaɣie blast cells ƒe dzidziɖedzi mefia kansa o. Nɔnɔme kple atikewɔwɔ aɖewo siwo menye kansa o hã ate ŋu ana blast cells nage ɖe ʋua me hena ɣeyiɣi aɖe.

• Dɔlékui sesẽwo: Ne ŋutilãa xɔ dɔlékui sesẽ aɖe abe `Sepsis` ene la, míaƒe ŋutilã dzea ʋumenugbagbevi ɣiwo wɔwɔ gɔme wògbɔa eme be woatsɔ awɔ avu kple dɔlékuia. Le ɣeyiɣi sia me la, blast cell aɖewo siwo metsi o hã ate ŋu age ɖe ʋua me tso ƒumeŋuɖui me.
• G-CSF dɔdamɔnu: Ne wole kansa dada abe atikewɔmɔnu ene wɔm la, ʋumenugbagbevi ɣiawo dzi ɖena kpɔtɔna. Ɣemaɣi la, wodoa atike si woyɔna be `Granulocyte-colony stimulating factor (G-CSF)` tsɔ doa ŋusẽ ʋumenugbagbevi ɣiwo ƒe wɔwɔ. Atike sia ate ŋu ana blast cells ƒe xexlẽme nadzi ɖe edzi le ʋua me hã hena ɣeyiɣi aɖe.
• Lãmenugbagbeviwo dodo na ame: Ne wodo lãmenugbagbeviwo na nɔnɔme aɖe vɔ la, blast cells ƒe xexlẽme ate ŋu adzi ɖe edzi le ʋu yeyewo dodo me.

Gake nu vevitɔe nye be zi geɖe la, blast cell siawo siwo menye kansa o la dzena le lãmesẽ me le nusuekpɔmɔ̃ me. Woate ŋu awɔ woƒe dɔ ne wole tsitsim. Le kansa me la, míekpɔa blast cells siwo mesɔ o, siwo ƒe nɔnɔme mesɔ o.

Aleke nèwɔna léa ŋku ɖe blast cell ƒe agbɔsɔsɔme ŋu?

Ðɔktawo zãa dodokpɔ vevi geɖe tsɔ srɔ̃a nu tso blast cells ŋu.

• Ʋu si Woɖena le Gome (PBS): .Esia bia be nàsi wò ʋu aɖe ɖe glass slide dzi ahalé ŋku ɖe eŋu le nusuekpɔmɔ̃ me. Esia wɔnɛ be nàte ŋu akpɔe ɖa be lãmenugbagbevi siwo wotsɔna gbãa nu le ʋua me hã, alesi wodzenae, kple alesi woƒe alafa memamã nye hã.
• Ƒumeŋuɖui dodokpɔ: Esiae nye mɔ nyuitɔ si dzi nàto akpɔ nyatakaka siwo de pɛpɛpɛ wu eye wode blibo wu tso blast cells ŋu. Ƒumeŋuɖui me ɖeɖe alo aspiration bia be woaɖe aŋe sue aɖe tso ƒu gã aɖe abe akɔtaƒu ene me, eye woaɖe ƒumeŋuɖui ƒe kpɔɖeŋu. Emegbe wodonɛ kpɔna le dodokpɔxɔ aɖe me be woanya lãmenugbagbevi siwo me woblaa nu le ƒe alafa memamã kple woƒe nɔnɔme tututu.
• Ʋu Xexlẽme Blibo (CBC): Esia léa ŋku ɖe wò ʋumenugbagbevi dzĩwo, ʋumenugbagbevi ɣiwo, kple ʋumenugbagbevi dzĩwo ƒe xexlẽme ŋu. Ne blast cells dzi ɖe edzi la, lãmenugbagbevi siawo siwo le lãmesẽ me ƒe xexlẽme ate ŋu aɖe akpɔtɔ.

Eyata mègatsi dzodzodzoe ne èkpɔ ‘blast’ le wò nyatakakaa dzi o. Ate ŋu anye nu vevi aɖe ƒe dzesi, eye ɣeaɖewoɣi la, ate ŋu anye nɔnɔme si anɔ anyi ɣeyiɣi kpui aɖe. Nu vevitɔe nye be nàƒo nu tso eŋu na wò ɖɔkta eye nàwɔ ɖe eƒe aɖaŋuɖoɖo dzi. Aɖo wò ɖe ʋuŋutinunyala gbɔ ne ehiã.