Ðe wò dɔgbo gbã le dɔlékuiwutikewo nono vɔ megbe kpɔa? Mina míasrɔ̃ nu tso C. diff (Clostridioides difficile) ŋu!

Ðe nèdze aɖuɖɔtoe sesẽ xɔxɔ gɔme nyitsɔ laa le dɔlékuiwutike nono vɔ megbea? Alo ɖe dɔgbo le veve sem eye aɖuɖɔtoe le fu ɖem na wò ŋkeke geɖea? Ate ŋu atso dɔlékui aɖe si ŋu míese nu geɖe tsoe o gbɔ, gake ate ŋu anye afɔku gã aɖe. Egbea, mina míaƒo nu tso nusi C. diff nye, nusita wòdzɔna, kple alesi míate ŋu akpɔ mía ɖokui tae ŋu.

Nukae nye C. diff (Clostridioides difficile)?

Kpuie ko la, C. diff nye ŋkɔ kpui si wotsɔ na dɔlékui ƒomevi aɖe. Eƒe ŋkɔ bliboae nye *Clostridioides difficile*. Dɔlékui sia ate ŋu axɔ míaƒe dɔgbo gã (dɔgbo) me. Ne ewɔe la, ehea aɖuɖɔtoe kple dzesi bubu gbogbo aɖewo siwo meɖea dzi ɖi o vɛ.

Enye nusi sɔ be dɔlékuiwo naxɔ wò dɔgbowo, eye wo dometɔ akpa gãtɔ menye esiwo nu sẽ o. Gake C. diff dɔlékui sia nu sẽ vie wu, eye ate ŋu agblẽ nu le wò dɔgbo me. Esia le alea elabena C. diff dɔlékuiawo wɔa aɖiwo le wò dɔgbowo me. Aɖi siawo gblẽa nu le lãmenugbagbevi siwo le wò dɔgbo ŋu, si wɔnɛ be wovuvuna. Le atikewɔwɔ me la, míeyɔa esia be dɔgbo ƒe dɔléle . Ne èkpɔ dzesiawo kple alesi wosẽe la nɔ te ɖe alesi gbegbe aɖiawo gblẽ nu le wò dɔgbo ŋui dzi. Le go aɖewo me la, nɔnɔme sia ate ŋu ade ame ƒe agbe afɔku me.

Nukae nye C. diff dɔlékui ƒe dzesiwo?

Dɔlékui sia ƒe dzesi vevitɔ kple gbãtɔe nye tsi ƒe ʋuʋu (aɖuɖɔtoe) . Ne dɔlékuia mesẽ o la, àte ŋu aɖe aɖuɖɔ abe zi etɔ̃ ene gbesiagbe, eye ƒodo me ʋuʋu vie akpe ɖe eŋu.

Ne dɔlékuia le sesẽm ɖe edzi la, aɖuɖɔtoea hã va le sesẽm ɖe edzi. Àte ŋu aɖe aɖuɖɔ ewo alo wuiatɔ̃ gbesiagbe. Àte ŋu ade dzesi ʋu le wò aɖuɖɔ me hã. Esiawo nye dzesi bubu siwo ate ŋu adze ne nɔnɔmea nu sẽ.

Gbã la, dzesi siawo ate ŋu adze abe nuɖuɖu me aɖi alo dɔgbo me dzamezã ene. Ne èle dɔlékuiwutikewo zãm la, àte ŋu asusui vodadatɔe be dɔgbo ƒe dɔmawɔmawɔ nyuie sia nye atike la ƒe nugbegblẽ le ame ŋu si sɔ.

Nukae nye aɖuɖɔ ƒe nɔnɔme le C. diff dɔlékui me?

Le C. diff aɖuɖɔtoe me la, zi geɖe la, aɖuɖɔa nɔa abe mɔli ene eye wòlolona, ​​metsina keŋkeŋ o. Ate ŋu anye amadede dama ɣeaɖewoɣi. Ɣeaɖewoɣi la, woate ŋu akpɔ ʋu, ʋuʋudedi, alo ʋuʋudedi.

Ame geɖe ka nya ta be ʋeʋẽ tɔxɛ aɖe le C. diff aɖuɖɔtoe ŋu . Woɖɔe be enye ʋeʋẽ si nu sẽ wu, si vivina etɔxɛ wu aɖuɖɔ si sɔ. Esia ate ŋu atso esi C. diff dɔlékuiwo dzia ʋumenugbagbeviɣidɔ ƒe agbɔsɔsɔ ɖe edzi le míaƒe aɖuɖɔ me ta.

Nukatae míekpɔa C. diff?

Bu míaƒe dɔgbo be enye seƒoƒobɔ dzeani aɖe. Le abɔ sia me la, seƒoƒo nyuiwo kple gbe aɖewo le afima. Le amesi ƒe dɔlélenutsiŋutete le lãmesẽ me ƒe dɔgbo me la, dɔlékui "nyui" geɖewo (abe seƒoƒowo ene) eye dɔlékui "vɔ̃ɖiwo" (abe gbewo ene) le wo dzi ɖum. C. diff nye dɔlékui aɖe si nɔa míaƒe dɔgbo me le agbɔsɔsɔ sue aɖe me le dzɔdzɔme nu.

Ne wogblẽ dadasɔ sia me, si fia be dɔlékui nyuiwo mesɔ gbɔ o la, mɔnukpɔkpɔ sua dɔlékui gbegblẽwo abe C. diff ene si be woakaka abe gbewo ene eye woaxɔ nɔƒea.

Aleke C. diff kakae?

C. diff dɔlékui la nyea adzame ŋutɔ. Ne edo le ŋutilãa me la, ewɔa go sesẽ aɖe ŋutɔ si woyɔna be spore. Dɔlékui siawo le abe dɔlékuiawo ƒe nuku suesuesuewo ene. Woate ŋu anɔ míaƒe asiwo dzi kple nusiwo ŋu míeka asi (ʋɔtruwo, kplɔ̃wo, tsileƒenuwo) dzi. Ne míeka asi anyigba si dzi lãmenugbagbevi siawo le ŋu la, míate ŋu adze dɔ, eɖanye nuɖuɖu ɖuɖu kple asi ɖeka alo míaƒe asiwo dede míaƒe nu me o.

Esesẽna ŋutɔ be woawu lãmenugbagbevi siawo. Wote ŋu nɔa te ɖe dzoxɔxɔ, aɖi, kple dɔlékuiwutike kple dɔlékuiwutike geɖe nu. Woate ŋu anɔ agbe le anyigba dzi hã ɣleti geɖe. Esia tae dɔléle sia kakana kabakaba alea gbegbe ɖo, vevietɔ le teƒewo abe kɔdziwo ene.

Amekawoe le afɔku gã me be woaxɔ C. diff?

Ame aɖewo ate ŋu axɔ dɔlékui sia. Woawoe nye:

• Ame siwo xɔ wu ƒe 65: Afɔkua lolo wu elabena dɔlélenutsiŋutete dzi ɖena kpɔtɔna ne ame tsi, wonoa atike geɖe na dɔléle bubuwo, eye wonɔa kɔdziwo alo ame tsitsiwo dzikpɔƒewo.
• Vidzĩ suewo: Elabena woƒe dɔlélenutsiŋutete metsi bliboe haɖe o.
• Ame siwo le kɔdziwo: Kɔdziwo nye teƒe si C. diff ƒe dɔlékuiwo ate ŋu akaka le bɔbɔe. Woate ŋu axɔe bɔbɔe to dutoƒo tsileƒewo kple nugododeƒewo me.
• Ame siwo ƒe dɔlélenutsiŋutete gbɔdzɔ: Ame siwo ŋu dɔlélewo abe kansa, HIV, ayikudɔ, kple suklidɔ le ƒe dɔlélenutsiŋutete gbɔdzɔ. Ame siwo zãa dɔlélenutsiŋutete ƒe atikewo hã le afɔku me wu.
• Ame siwo ŋu dɔgbomedɔlélewo le: Amesiwo ŋu dɔlélewo abe Inflammatory Bowel Disease (IBD) , abe Crohn ƒe dɔléle kple ulcerative colitis ene le la te ŋu xɔa dɔlékuiwo bɔbɔe wu elabena dɔgboa ƒe akpa si kpɔa wo ta la gbɔdzɔna.

Gake ɖo ŋku edzi be amesi si afɔku siawo dometɔ aɖeke mele o gɔ̃ hã ate ŋu axɔ C. diff.

Nukawoe nye kuxi siwo ate ŋu ado tso C. diff me?

Zi geɖe la, C. diff dɔlékuiwo mesẽna o. Gake ɣeaɖewoɣi, vevietɔ ne womewɔ atike nɛ o la, kuxi sesẽwo ate ŋu ado mo ɖa.

• Dɔlékuiwo xɔxɔ enuenu: Le atikewɔwɔ vɔ megbe gɔ̃ hã la, ame siwo ade 20% agaxɔ dɔlélea le kwasiɖa eve va ɖo enyi me.
• Tsikunɔamesi: Aɖuɖɔtoe si gbɔ eme nana tsi kple elektrikŋusẽ gbogbo aɖewo buna le ŋutilãa me. Ne esia va nu sẽ la, ate ŋu ana ʋu naɖiɖi eye ayiku gɔ̃ hã nawɔ dɔ nyuie.
• Pseudomembranous colitis ƒe dɔléle:Esia nye nɔnɔme sesẽ aɖe (colitis). Dɔgboa ƒe akpa si le eme la xɔa dzo eye wòtsina abe lãkusi ene.
• Megacolon si me aɖi le: Esia nye nɔnɔme si mebɔ o gake afɔku le eme ŋutɔ. Dɔgboa vuvu ale gbegbe be medzudzɔa dɔwɔwɔ kura. Esia ate ŋu ana ame naxɔ dɔlékuiwutikewo, si nye nɔnɔme si me dɔlékuiwo kakana le ŋutilã bliboa me.

Le nɔnɔme sesẽ siawo tɔgbe me la, ate ŋu ahiã gɔ̃ hã be woawɔ dɔ nɛ be woaɖe dɔgboa ƒe akpa si ŋu dɔlékuia le la ɖa.

Ðɔkta, aleke nèwɔna dea dzesi dɔléle sia? Nukae nye atikewɔwɔa?

Ne wò ɖɔkta susui be C. diff dɔlékui aɖe le ŋuwò le wò dzesiwo ta la, abia tso asiwò be nàna aɖuɖɔ ƒe kpɔɖeŋu. Woaɖoe ɖe dodokpɔxɔ aɖe be woadoe akpɔ be C. diff ƒe aɖiwo le eme hã.

Ne woɖo kpe dɔlélea dzi la, woate ŋu awɔ ʋudodokpɔwo eye ɖewohĩ woawɔ fotowo atsɔ alé ŋku ɖe dɔgboa me be woanya alesi gbegbe dɔlélea nu sẽe.

Dɔdamɔnu siwo wozãna

Atikewɔwɔ nɔ te ɖe alesi dɔlélea nu sẽe dzi.

• Dɔlékuiwutikewo dzudzɔ: Ne èxɔ C. diff esime nèle dɔlékuiwutikewo nom na dɔléle bubu la, nu gbãtɔ si wò ɖɔkta awɔe nye be nàdzudzɔ atikeawo zazã. Le ame aɖewo gome la, ema koe wòle be woawɔ. Dɔlékui nyui siwo le wò dɔgbo me agatsi ake eye dɔlékuia akɔ le eɖokui si.
• C. diff-specific antibiotics: Ne ema mewɔ dɔ o la, wò ɖɔkta ate ŋu aŋlɔ dɔlékuiwutike aɖe koŋ si ate ŋu awu C. diff dɔlékuiawo na wò. Le kpɔɖeŋu me , (Metronidazole) , (Vancomycin) , alo (Fidaxomicin) .
• Kɔdziyiyi: Ne dɔlélea nu sẽ la, ahiã be woaxɔ wò ɖe kɔdzi, afisi woate ŋu ana saline (IV fluids) kple dɔlékuiwutike siwo wodona ɖe ʋuka me wò.

Nukae woawɔ tso dɔlékui siwo gbugbɔna dzɔna ŋu?

Ame aɖewo gadzea dɔa gɔme ake le atikewɔwɔ vɔ megbe. Le nɔnɔme mawo me la, tiatia siwo nàte ŋu awɔe nye:

• Gbugbɔgawɔ dɔlékuiwutikewo: Woate ŋu aŋlɔ dɔlékuiwutike bubu alo atike si wozãna ɣeyiɣi didi aɖe na ame.
• Fecal Microbiota Transplant (FMT): Ŋkɔ sia aɖi nusi wɔ nuku vie, gake enye atike nyui aɖe ŋutɔ na C. diff si gbugbɔna. Kpuie ko la, ebia be woaɖe dɔlékui ‘nyuiawo’ ɖe vovo tso aɖuɖɔ si woɖe tso ame si le lãmesẽ me gbɔ eye woatsɔ wo ade dɔnɔa ƒe dɔgbo me. Esia nana dɔlékui nyui siwo bu le dɔgboa me la gada asɔ.

Nukae wòle be míawɔ be míaxe mɔ ɖe C. diff ƒe kaka nu?

Esi dɔléle sia xɔa ame me ŋutɔ ta la, ehiã be míaɖɔ ŋu ɖo ŋutɔ. Vevietɔ ne dɔléle sia le ame aɖe ŋu le ƒomea me la, kpɔ egbɔ be yewɔ nusiawo.

• Ameɖeɖe ɖe aga: Anyo wu be nàna amesi ŋu dɔlélea le la nanɔ xɔ si le vovo me ne anya wɔ. Enyo wu gɔ̃ hã ne woate ŋu azã nugododeƒe si woɖe ɖe vovo. Ne èzãa dutoƒo nugododeƒe la, tsɔ atike si me bleach le tutu nugododeƒea ƒe anyime ɣesiaɣi ne èzãe vɔ.
• Klɔ anyigba dzi: Klɔ teƒe siwo ŋu nèka asi enuenu le (ʋɔtru ƒe nugbɔwo, akaɖi ƒe ʋuƒo) kple tsi si me bleach le.
• Dɔlékuiwutikewo zazã nyuie: Mègano dɔlékuiwutike siwo ɖɔkta meŋlɔ na wò o la gbeɖe o. No atike bliboa abe alesi woŋlɔe ene.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Ne dzesi siawo le ŋuwò la, yi ɖɔkta gbɔ enumake.

• Ne aɖuɖɔtoetetedɔ dze dziwò le dɔlékuiwutikewo zazã gɔmedzedze vɔ megbe.
• Ne aɖuɖɔtoe sesẽ (wu zi 10 gbesiagbe).
• Ne èkpɔ ʋu le wò aɖuɖɔ me.
• Ne dɔgbo le veve sem vevie eye asrã le ŋuwò.
• Ne èle ʋuʋum ale gbegbe be màte ŋu aɖu nu alo ano nu o.

Ne èkpɔ dzesi siawo dometɔ aɖe la, yi kɔdzi ƒe Dɔwɔƒe si Kpɔa Nudzɔdzɔ Kpatawo Gbɔ (ETU) enumake:

• Tsikuɖiɖi ƒe dzesiwo (nu me ƒuƒu, ŋku siwo nyrɔ, aɖuɖɔ si mebɔ o ŋutɔ, ɖeɖiteameŋu si gbɔ eme).
• Dɔgbo ƒe vevesese sesẽ si womate ŋu ado dzi atsɔ o.
• Ŋkuɖodzinyawo ƒe tɔtɔ.

C. diff menye dɔléle si woabu nu tsɛe o. Gake mègatsi dzodzodzoe o. Ne èyi ɖɔkta gbɔ le ɣeyiɣi nyuitɔ dzi eye nèxɔ atike la, ate ŋu adae keŋkeŋ.