Ðewohĩ wò ɖɔkta ŋlɔ atike aɖe si woyɔna be Chlorpromazine na wò alo wò ƒomea me tɔ aɖe. Ne èse ŋkɔ sia la, ɖewohĩ àse le ɖokuiwò me be vɔvɔ̃ ɖo vie alo adi be yeanya nu tso eŋu. Esɔ be woabia nya abe, ‘Nukae nye atike sia? Nukatae wole esia nam?’ be wòava susu me na wò. Esi wònye be esia nye atike si wonana zi geɖe ɖe susumedɔlélewo ta la, nukpɔsusu totro vovovowo ate ŋu anɔ amewo dome. Eyata egbea, mina míaƒo nu tso chlorpromazine-tike sia ŋu le mɔ bɔbɔe aɖe si gɔme nàte ŋu ase nu.
Nuka tututue nye Chlorpromazine?
Kpuie ko la, chlorpromazine nye atike si wozãna tsɔ daa susumedɔléle geɖe. Enɔ atikewo ƒe hatsotso aɖe si woyɔna be tagbɔdɔlékuiwutikewo me . Dopamine nye atike aɖe si le ahɔhɔ̃a me si kpena ɖe mía ŋu míeɖua nuwo abe míaƒe seselelãme kple seselelãmewo ene dzi. Atike sia wɔa dɔ to dopamine sia ƒe agbɔsɔsɔ si le ahɔhɔ̃a me dadasɔ me.
Ke hã, menye tagbɔdɔlélewo koe woŋlɔna na atike sia o. Ðɔktawo zãnɛ le nɔnɔme bubu geɖewo me. Le kpɔɖeŋu me:
- Tagbɔdɔlélewo abe tagbɔdɔléle kple tagbɔdɔléle ene.
- Kpɔ ʋuʋudedi kple ʋuʋudedi dzi.
- Le hiccups siwo le edzi yim ɣeyiɣi didi aɖe eye womate ŋu atɔ te wo o ta.
- Le dɔléle si woyɔna be porphyria ƒe nɔnɔme aɖewo gome.
- Na lãmekawo naɖe dzi ɖi le tetanus ƒe ɣeyiɣia me.
- Na dɔnɔa ƒe dzi nadze eme hafi woawɔ dɔ nɛ alo adoe kpɔ le atikewɔwɔ me.
Nusiwo wòle be nàgblɔ na wò ɖɔkta hafi ano atike sia
Hafi nàdze atike sia zazã gɔme la, ele vevie ŋutɔ be nàna wò ɖɔkta naƒo nu tso wò lãmesẽnyawo ŋu bliboe. Elabena ele be woaɖɔ ŋu ɖo le atike sia zazã me le amesiwo ŋu dɔléle aɖewo le ŋu. Ne dɔléle siwo woŋlɔ ɖe ete dometɔ aɖe le ŋuwò la, kpɔ egbɔ be yegblɔe na wò ɖɔkta.
| Nɔnɔme/susu si sɔ | Nuɖᴐɖᴐ |
|---|---|
| Atikewɔwɔ ƒe nɔnɔme siwo li fifia | Ahɔhɔ̃ me dɔdzẽ, tagbɔdɔléle, suklidɔ, ŋkudɔ, ta ƒe abixɔxɔ, dzidɔ, dzi ƒe tsotso si mesɔ o ƒe ŋutinya, ayiku alo aklãdɔ, ʋu ƒe sisi, lãkusidɔ abe asrã, Parkinson ƒe dɔléle, ʋuka me dɔléle, alɔ̃madɔmadɔ. |
| Ŋutilã ƒe vevesese | Nuɖuɖu mimi sesẽ, dɔgbo ƒe ʋuʋu dzi ɖuɖu sesẽ, aɖuɖɔtoe sesẽ, kple dɔgbo ƒe xexe. |
| Kuxi siwo do ƒome kple ʋu | Nɔnɔmewo abe ʋumenugbagbevi ɣiwo ƒe ɖiɖi, ʋumenugbagbevi dzĩwo, alo ʋumenugbagbevi dzĩwo ene. |
| Agbenɔnɔ kple numamewo | Ne ènye amesi noa aha enuenu. |
| Nusiwo ŋu nulɔdɔ le | Ne chlorpromazine, sulfites, atike bubuwo, nuɖuɖuwo, amadedewo alo nusiwo wotsɔ dzraa nu ɖo ƒe nulɔdɔ le ŋuwò. |
| Nudzɔdzɔ tɔxɛwo | Ne èfɔ fu, nèle agbagba dzem be yeafɔ fu, alo nèle no nam. |
Aleke wonaa atike siae?
Esia menye atike si nàte ŋu atsɔ ayi aƒemee o. Chlorpromazine nye atike si atikewɔla aɖe dona le kɔdzi alo atikewɔƒe . Wodonɛ ɖe ŋutilãa me to atike dodo ɖe lãmeka me alo dodo ɖe ʋuka me.
Ele be woakpɔ nyuie etɔxɛe ne wole atike sia nam ɖeviwo. Togbɔ be wokafui le nɔnɔme tɔxɛ aɖewo me na ɖevi siwo xɔ wu ɣleti 6 hã la, ele vevie be woawɔ ɖe afɔɖeɖe siwo sɔ dzi.
Agbɔsɔsɔ si gbɔ eme - Ele vevie ŋutɔ!
Ne èsusu be yeno atike sia fũu akpa la, mègaŋe aɖaba ƒu edzi gbeɖe o. Yi kɔdzi ƒe Dɔwɔƒe si Kpɔa Nudzɔdzɔ Kpatawo Gbɔ (ETU) enumake. Ne ehiã la, àte ŋu aƒo ka na Dukɔa ƒe Aɖi Ŋuti Nyatakaka Dɔwɔƒe si le Colombo Dukɔa ƒe Kɔdzi axɔ aɖaŋuɖoɖo.
Atike bubu siwo ate ŋu awɔ dɔ kple atike sia
Ele vevie ŋutɔ be nàgblɔ atike siwo katã nèzãna na wò ɖɔkta, elabena chlorpromazine ate ŋu awɔ dɔ kple atike bubu geɖe.
| Mègano chlorpromazine kpe ɖe esiawo ŋu gbeɖe o. | |
|---|---|
| Cisapride ƒe nya | Pimozide ƒe atike |
| Dronedarone si woyɔna be Dronedarone | Saquinavir ƒe atike |
| Metoclopramide ƒe atike | Thioridazine ƒe atike |
| Kpɔ nyuie vevietɔ elabena kuxiwo ate ŋu ado mo ɖa le amesiawo hã ŋu. | |
| Ahasesẽ | Lithium si woyɔna be lithium |
| Atike siwo wua histamine na nulɔdɔwo, kɔdzidɔ, kple dzamezã | Ʋusɔgbɔdɔ ƒe atikewo |
| Atike siwo wozãna na nuteɖeamedzi, dzimaɖitsitsi, alo alɔ̃dɔdɔ | Atike siwo tsia ʋuʋudedi nu (Phenobarbital, Phenytoin) . |
| Atike siwo wozãna na Parkinson ƒe dɔléle (Levodopa) . | Atike siwo naa atike muamewo |
| Atike siwo wozãna tsɔ naa ame dɔa alɔ̃ le amekoko me | Ʋumenugbagbeviɣitikewo abe Warfarin ene |
Nusiwo woŋlɔ ɖi sia mede blibo o, eyata kpɔ egbɔ be yegblɔ atike, vitamin, alo atike siwo wozãna tsã siwo zãm nèle la na wò ɖɔkta.
Nusiwo ŋu wòle be woabu ne wole atikewo nom
Wò atikewɔlawo ƒe ƒuƒoƒoa alé ŋku ɖe wò nɔnɔmea ŋu nyuie esime nèle atike sia xɔm, gake ele vevie be nànya nyateƒenya siawo.
Alɔ̃dɔdɔ kple taɖuame
Atike sia ate ŋu ana nàse le ɖokuiwò me be yedɔ alɔ̃, yeƒe ta natsi, alo yeƒe ŋkuwo megakpɔa nu nyuie o . Eyata ƒo asa na nuwɔna siwo me afɔku le abe ʋukuku alo mɔ̃wo zazã ene vaseɖe esime nànya alesi atike sia gblẽa nu le ŋuwòe. Kpɔ nyuie ne èfɔ alo bɔbɔ nɔ anyi kpata , vevietɔ ne ètsi. Esia ate ŋu aɖe mɔnukpɔkpɔ si li be ame natsi dzodzodzoe ahadze anyi dzi akpɔtɔ. Ahanono ate ŋu ana alɔ̃dɔdɔ sia nagado gã ɖe edzi.
Ŋutilã ƒe dzoxɔxɔ dzi kpɔkpɔ
Atike sia ate ŋu akpɔ ŋusẽ ɖe wò ŋutilã ƒe ŋutete be wòaɖɔ dzoxɔxɔ ɖo dzi. Ðewohĩ wò dzidodo ɖe vuvɔ ŋu dzi aɖe akpɔtɔ, eye wò mɔɖeɖe ɖe dzoxɔxɔ ŋu hã dzi aɖe akpɔtɔ. Eyata do awu siwo me dzo le le ŋkeke siwo dzi vuvɔ le wɔwɔm. Le ŋkeke siwo dzi yame xɔ dzo la, seɖoƒe na ŋdɔkutsu dzatsɛ, de kame, eye nàno tsi geɖe.
Ɣe ƒe seselelãme
Atike sia ate ŋu ana wò ŋutigbalẽ nase veve ɖe ŋdɔkutsu nu. Eyata kpɔ ɖokuiwò ta tso ɣea si me. Ne ele be nàdo go le ŋdɔ me la, do awu siwo atsyɔ wò ŋutilã eye nàzã ɣe ƒe keklẽŋusẽtike .
Nu ƒuƒu
Nu me ƒuƒu nye atike sia ƒe nugbegblẽ le ame ŋu si bɔ. Woate ŋu akpɔ esia gbɔ to aŋe si me sukli mele o ɖuɖu, akpɔnɔ vivi si womevivi o nono, kple tsi geɖe nono me.
Nukawoe nye nusiwo ate ŋu ado tso eme?
Abe atike ɖesiaɖe ene la, chlorpromazine ate ŋu agblẽ nu le ame ŋu. Wo dometɔ aɖewo nye nya veviwo, ɖewo bɔ. Ele vevie be nànya nusiawo.
| Nusiwo wògblẽna le ame ŋu siwo wòle be nàgblɔ na wò ɖɔkta alo kɔdzi enumake | |
|---|---|
| Nusiwo ŋu nulɔdɔ le | Ŋutilã ƒe ʋuʋu, ʋuʋudedi, mo, nuyi, aɖe alo ŋɔti ƒe vuvu. |
| Ahɔhɔ̃mekawo ƒe Dɔléle Vɔ̃ɖi | Asrã sesẽ kpata, lãmekawo ƒe sesẽ, fifia fũ, dzi ƒe tsotso kabakaba alo esi mesɔ o, tɔtɔ. |
| EPS ƒe dzesiwo (Extrapyramidal Symptoms) . | Ŋutilã ƒe akpa aɖewo ƒe ʋuʋu si dzi womeɖu o (vevietɔ mo, nu), lãmekawo ƒe sesẽ, ʋuʋudedi, dadasɔ, ɖiɖiɖeme. |
| Aklã ƒe gbegblẽ | Vevesese le ɖusime ƒodo si le etame, nuɖuɖu ƒe dzodzro, ʋuʋudedi, ŋutigbalẽ alo ŋku ƒe ɣie, aɖuɖɔ si le ɣie/blɔ viviti, kple aɖuɖɔ si ƒe amadede le keklẽm. |
| Dzesi sesẽ bubuwo | Dɔlékui ƒe dzesiwo (asrã, vuvɔ, kɔdzi, ŋɔti me veve), ʋu ƒe sisi (taɖuame, alɔ̃madɔmadɔ). |
| Nu siwo zi geɖe menye nu sesẽ o, gake ele be woagblɔe na ɖɔkta ne woyi edzi | |
| Miléle | Nu ƒuƒu |
| Alɔ̃dɔdɔ | Kpekpeme ƒe dzidziɖedzi |
| Taɖuame | |
Ne èkpɔ dzesi bubu aɖewo siwo mebɔ o siwo womeyɔ le xexlẽdzesi sia me o la, ƒo nu tso wo hã ŋu na wò ɖɔkta.
Gbedasi si Wotsɔ Yi Aƒeme
- Chlorpromazine nye atike si wozãna le kɔdzi alo atikewɔƒe le ɖɔkta ƒe dzikpɔkpɔ te ko.
- Kpɔ egbɔ be yegblɔ atike bubu siwo katã zãm nèle, atikewɔwɔ ƒe nɔnɔme bubu ɖesiaɖe si le ŋuwò, kple nulɔdɔ ɖesiaɖe si le ŋuwò na wò ɖɔkta.
- Kpɔ nyuie ne èle dɔ siwo hiã be nànɔ ŋudzɔ, abe ʋukuku ene, wɔm elabena alɔ̃dɔdɔ kple taɖuame ate ŋu adzɔ ne èle atikeawo nom. Ƒo asa na ahanono.
- Ne èkpɔ nugbegblẽ sesẽ aɖewo abe dzoxɔxɔ sesẽ, lãmekawo ƒe sesẽ, ŋutilã ƒe ʋuʋu si dzi womate ŋu aɖu o, alo ŋutigbalẽ ƒe ɣie ene la, di atikewɔlawo ƒe aɖaŋuɖoɖo enumake.
- Ne dzimaɖitsitsi alo vɔvɔ̃ aɖe le ŋuwò le atike sia ŋu la, ƒo nu tso eŋu na wò ɖɔkta gaglãa.
👩🏽 ⚕️ Nyabiase bubuwo (FAQs)
💬 Chlorpromazine Injection / Thorazine nye atike sesẽ aɖe ŋutɔ si wozãna tsɔ daa dɔléle ka?
Esia menye atike dzro aɖe ko o! Esia nye atike xoxotɔ kekeake si ŋu ŋusẽ le wu (First-Generation Antipsychotic) si wozãna kpata si wozãna tsɔ naa dɔnɔa ƒe dzi dzea eme enumake eye wònana wòdɔa alɔ̃ vevie (si naa ame ƒe dzi dzea eme) le ‘susu ƒe tagbɔsesẽ’ sesẽ (Severe Psychosis/Agitation) si tagbɔdɔléle, tagbɔdɔléle, kple atikewo hena vɛ, ne dɔnɔa tsi dzodzodzoe le mɔ si dzi womeɖu o nu, eye wòle le afɔku gã aɖe me be yeawɔ nuvevi ame bubuwo alo ye ŋutɔ.
💬 Ne èle ɣli dom/do ɣli abe tagbɔsesẽ ene la, aleke atike sia (Chlorpromazine) kpena ɖe wò ahɔhɔ̃ ŋu wòdaa gbe/dɔa alɔ̃?
Wokpɔa/woɖea fu na nu wɔnuku mawo ŋutɔ ne atike si nye ‘Dopamine (Dopamine / D2)’ si le ahɔhɔ̃a me yɔ fũ! Atike sia xea mɔ/tua ‘Dopamine xɔla’ siwo katã le ahɔhɔ̃a me (Dopamine antagonist) keŋkeŋ eye wòxea wo. Tsɔ kpe ɖe eŋu la, etsia mɔ̃awo hã le ‘Histamine (H1)’ kple ‘Adrenaline (Alpha-1)’ ƒe afɔɖeɖewo me, eyata dɔnɔa zi ɖoɖoe eye wòbɔbɔ nɔ anyi kpoo/mlɔ anyi le miniti ʋee aɖewo megbe.
💬 Nukae nye atike sia si gblẽa nu le ahɔhɔ̃ ŋu vevie (Thorazine) ƒe nugbegblẽ le ame ŋu (Black Box Warnings)?
Afɔku gãtɔe nye be ne wotsɔ esia na ame tsitsi siwo ŋu tagbɔdɔléle (Dementia-related psychosis) le la, woate ŋu adzudzɔ gbɔgbɔ zi ɖeka aku (Increased mortality)! Nu bubu si me afɔku le wu enye be esia ateŋu ana dɔnɔa nadze alɔ̃ me le 'Fatal Hypotension / Orthostatic' ta. Azɔ hã, ahɔhɔ̃medɔ sesẽ aɖe si wɔnɛ be womate ŋu anɔ anyi kpoo o, si ana abɔwo naʋuʋu abe tagbɔsesẽ ene eye kɔ/ŋkuwo naʋuʋu (Extrapyramidal Symptoms / EPS / Tardive Dyskinesia) ate ŋu adzɔ godoo.
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