Ðe wò asibidɛwo kple afɔbidɛwo biã eye wòxɔ dzoa? Ate ŋu anye Asi-Afɔ ƒe Dɔléle''!

Ne èle kansa ƒe atikewo zãm, alo nènya ame aɖe si le dɔ wɔm na wò la, àte ŋu akpɔ tɔtrɔ vi aɖe, abiã, avuvu, alo ave wò asibidɛwo kple afɔkpodzi ɣeaɖewoɣi. Le ame aɖewo gome la, esia ate ŋu anye nuteƒekpɔkpɔ si ɖea fu na ame vie. Mègatsi dzi o, esia nye nusi bɔ. Egbea míele nu ƒom tso nɔnɔme sia si woyɔna be Hand-Foot Syndrome - HFS'' , alo abe alesi ɖɔktawo yɔnae ene be Palmar-Plantar Erythrodysesthesia'' ŋu .

Nukae nye Asi-Afɔ ƒe Dɔléle''? Mina míase egɔme bɔbɔe!

Kpuie ko la, Asi-Afɔ ƒe Dɔléle'' nye ŋutigbalẽ ƒe dɔwɔwɔ si chemotherapy'' atike aɖewo hena vɛ. Etɔxɛe la, wò asibidɛwo kple afɔkpodziwo ate ŋu abiã, avuvu, eye ɣeaɖewoɣi wòase veve. Esia nye dɔdzẽ dada ƒe nugbegblẽ le ame ŋu si bɔ. Eyata ele vevie be nànya esia.

Atike ƒomevi kawoe hea Asi-Afɔ ƒe Dɔléle vɛ?

Menye atike siwo wozãna tsɔ daa dɔe katãe hea nɔnɔme sia vɛ o. Gake atike aɖewo li siwo ŋu woke ɖo be woate ŋu ahee vɛ wu. Wode dzesi "Asi-Afɔ ƒe Dɔléle" sia zi gbãtɔ esime wona atike si nye "cytarabine" ƒe agbɔsɔsɔ gã ʋumenugbagbeviɣidɔlélawo.

Atike ƒomevi siwo bɔ wu siwo hea HFS vɛ enye:

• (Capecitabine)
• (Docetaxel)
• (Pegylated liposomal doxorubicin - PLD)
• (5-fluorouracil)

Atikewɔmɔnu bubuwo li siwo ate ŋu ahe HFS vɛ, togbɔ be le mɔ sue aɖe ko nu hã:

• (Bleomycin)
• (Cisplatin)
• (Siklofosfamide)
• (Daunorubicin)
• (Doxifluridine)
• (Etoposide)
• (Fludarabine)
• (Gemcitabine)
• (Hydroxyurea)
• (Idarubicin)
• (Ixabepilone)
• (Methotrexate ƒe atike)
• (Mitotane)
• (Paclitaxel)
• (Tegafur)
• (Tiotepa)
• (Vinorelbine)

Ne èle atike siawo dometɔ aɖe zãm la, anyo be nàɖɔ ŋu ɖo vie le (HFS)'' ŋu. Gake ɖo ŋku edzi be menye amesiame si noa atike siawoe axɔe o.

Nukae nye afɔku siwo ate ŋu ana woaxɔ Asi-Afɔ ƒe Dɔléle''?

Nu vevitɔe nye (chemotherapy) atike agbɔsɔsɔme si wona wò kple mɔnu si wozãna na wò . Bu eŋu kpɔ, ne (chemotherapy) atike si wona wò sɔ gbɔ, alo ne èle atike la nom atraɖii la, mɔnukpɔkpɔ si li be nàxɔ nɔnɔme sia lolo. Eyae nye be, ne (chemotherapy) atike geɖe le wò ŋutilã me ɣeyiɣi didi aɖe la, afɔku si le (HFS) xɔxɔ me lolo ŋutɔ.

Nukae nye Asi-Afɔ ƒe Dɔléle'' ƒe dzesiwo? Aleke míewɔna dea dzesii?

Zi geɖe la, dzesi siawo dzea egɔme dzena le kwasiɖa eve va ɖo etɔ̃ megbe tso esime wodze atikewɔmɔnu zazã gɔme. Gbã la, àte ŋu ase le ɖokuiwò me be yeƒe asiwo kple afɔwo le ƒoƒom vie. Emegbe la, àte ŋu ade dzesi dzesiwo abe:

• Asiwo kple afɔwo ƒe vuvu kple woƒe amadede ƒe tɔtrɔ: Ame siwo ƒe ŋutigbalẽ le ɣie, alo amesiwo ƒe melanin mesɔ gbɔ o, ate ŋu ade dzesii be asibidɛwo kple afɔkpodziwo biã (si sɔ kple ɣe ƒe dzoxɔxɔ). Ame siwo ƒe ŋutigbalẽ le blɔ alo yibɔ, alo amesiwo ƒe ŋutigbalẽ me melanin sɔ gbɔ ɖo la ate ŋu ade dzesii be ŋutigbalẽa do viviti le asibidɛwo kple afɔkpodziwo ŋu.
• Asibidɛwo ƒe vuvu: Ate ŋu adze avuvu wu, vevietɔ le teƒewo abe asibidɛwo ƒe nugbɔwo ene.
• Ŋutilã ƒe tete, vevesese, alo veve ne woka asi eŋu: Ŋutilã ate ŋu ase le eɖokui me be yeate alo avee ne woka asi eŋu.
• Ŋutilã ƒe ʋuʋu alo eƒe ʋuʋu: Ɣeaɖewoɣi la, ŋutigbalẽa ate ŋu aʋuʋu eye wòaɖe.
• Vevesese ne afɔti alo afɔkpodzi ƒo nane: Le kpɔɖeŋu me, àte ŋu ase veve ne èle zɔzɔm alo ka asi nane ŋu.

Dzesi siawo ate ŋu anɔ bɔbɔe ŋutɔ eye vevesese aɖeke manɔ ame aɖewo ŋu o, evɔ ame bubuwo ya ate ŋu ase veve vevie si ana be womate ŋu awɔ gbesiagbedɔwo o.

Aleke ɖɔktawo wɔa dea dzesi Asi-Afɔ ƒe Dɔléle''?

Ne wò ɖɔkta alo dɔnɔdzikpɔla kpɔ dzesi siawo esime nèle atikewo zãm la, woasusui be Asi-Afɔ ƒe Dɔlélee.

Ke hã, ne èle kansatike ƒomevi aɖe si woyɔna be (multikinase inhibitors) hã ​​nom la, ahiã be wò ɖɔkta nabu nu bubu aɖe ŋu. Ema nye nɔnɔme si woyɔna be (Asi-Afɔ Ŋutilã ƒe Dɔwɔwɔ - HFSR). Esia hã nye (multikinase inhibitors) ƒe nugbegblẽ le ame ŋu. (HFSR) hã ​​hea ŋutigbalẽ ƒe tɔtrɔ vɛ. Le kpɔɖeŋu me, ŋutigbalẽ si le veve sem, si le ɣie, si le ɣie ate ŋu adze le teƒewo abe ƒunukpeƒewo, afɔkpodziwo, kple asibidɛwo ene.

Le esia ta la, ɖɔkta ate ŋu axɔ ŋutigbalẽ me lãmenugbagbeviwo le asiwò ɣeaɖewoɣi ahalé ŋku ɖe wo ŋu le nusuekpɔmɔ̃ me be yeanya nenye be HFS alo HFSR le ŋuwò tututu.

Ðe mɔ aɖe li si dzi woato adzidze Asi-Afɔ ƒe Dɔléle'' ƒe sesẽmea?

Ẽ, Dukɔa ƒe Kansa Ŋuti Nusrɔ̃ƒe to mɔnu aɖe vɛ be woatsɔ ade nɔnɔme sia ƒe sesẽme hatsotsowo me, si woyɔna be dzesideɖoɖo . Wò ɖɔkta atso nya me le alesi wòawɔ atike na wò ŋu le wò HFS ƒe dzeside nu.

• (Grade 1) Asi-Afɔ ƒe Dɔléle: Ate ŋu adzɔ be asibidɛwo kple afɔkpodziwo navuvu eye woƒe amadede natrɔ (abiã alo woazu yibɔ), gake vevesese aɖeke manɔ anyi o .
• (Grade 2) Asi-Afɔ ƒe Dɔléle: Tsɔ kpe ɖe (Grade 1) ƒe dzesiwo ŋu la, ate ŋu anye be ʋuʋudedi, ʋu nado, kple ŋutigbalẽa ƒe ʋuʋu. Vevesese ate ŋu anɔ anyi si ana gbesiagbedɔwo wɔwɔ nasesẽ .
• (Grade 3) Asi-Afɔ ƒe Dɔléle: Dzesiawo nu sẽ wu esiwo le (Grade 2). Vevesesea ate ŋu asẽ ale gbegbe be womate ŋu awɔ dɔ siwo sɔ gɔ̃ hã o . Ate ŋu asesẽ be nàdo awu, aɖi tsi, alo ayi nugododeƒe.

Nukae nye atike siwo wozãna na Asi-Afɔ ƒe Dɔléle''?

Azɔ na míakpɔ nusi esia ate ŋu awɔ. Ne wò dzesiawo nu sẽ ŋutɔ, si fia be wole ŋusẽ kpɔm ɖe wò agbenɔnɔ dzi ale gbegbe be màte ŋu anɔ agbe abe alesi wòle ene o la, wò ɖɔktawo ate ŋu atso nya me be yewoadzudzɔ atikewɔmɔnua hena ɣeyiɣi aɖe, aɖe atikeawo zazã dzi akpɔtɔ, alo atrɔ wò ɖe atike bubu ŋu.

Gake ɣeaɖewoɣi la, tɔtrɔ siawo wɔwɔ ate ŋu akpɔ ŋusẽ sue aɖe ɖe kansa dada ƒe dzidzedzekpɔkpɔ dzi. Ne edzɔ alea la, ne wò dzesiawo mesẽ akpa o la, wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be mɔ siwo dzi nàto akpɔ eƒe nugbegblẽ le ame ŋu gbɔ.

Nukae míate ŋu awɔ atsɔ aɖu dzesiawo dzi?

Ame geɖe ate ŋu akpɔ Asi kple Afɔ ƒe Dɔléle ƒe dzesiwo gbɔ to tɔtrɔ bɔbɔe aɖewo wɔwɔ le agbenɔnɔ me. Àte ŋu akpɔ gbɔdzɔe ne èwɔ nu siwo gbɔna:

• Zã corticosteroid-tikewo: Ðɔkta ate ŋu aŋlɔ atike sia ƒomevi na wò be wòaɖe abi kple abi dzi akpɔtɔ.
• De tsilétikewo - atike siwo naa tsi nɔa lãme na ame: Be wò ŋutigbalẽ nagaƒu o eye tsi nanɔ eme nyuie la, ele vevie be nàzã tsilénu. Wogayɔa esiawo be nusiwo nana ame ƒe lãme fa. Zã wo zi geɖe gbesiagbe.
• Zã vevesesenutsitikewo: Àte ŋu ano atikekui siwo woano alo atike siwo wozãna ɖe lãme na ame hena vevesese, abe alesi wò ɖɔkta gblɔe ene.
• Takpɔ wò ŋutigbalẽ ta tso dzoxɔxɔ me: Le kpɔɖeŋu me, mègakpɔ ŋdɔkutsu dzatsɛ, tsi dzodzoe, kple afɔwo tsɔtsɔ de tsi dzodzoewo me o.
• De tsikpe alo avɔ fafɛwo: Be ʋu naɖe wò asiwo kple afɔwo dzi akpɔtɔ la, tsɔ tsikpe alo avɔ dzadzɛ siwo wotsɔ tsi fafɛ ƒo ɖe wò asibidɛwo kple afɔkpodziwo dzi abe miniti 15-20 ene. Gake mègatsɔ tsikpe la asisi ɖe wò ŋutigbalẽ ŋu tẽ o, xatsae ɖe avɔ me.
• Na wò abɔwo kple afɔwo nakɔ: Ne èbɔbɔ nɔ zikpui dzi la, na wò afɔwo nakɔ, eye ne èle alɔ̃ dɔm la, na akɔtaɖonu nanɔ wò afɔwo te. Nenema kee wòle le wò abɔwo hã gome.
• Tsɔ asi ƒo wò ŋutigbalẽ blewuu: Eɖanye atike si wotsɔna ƒoa ŋutigbalẽe nèle sisim alo tsɔ afɔkpa le wò ŋutigbalẽ ƒom o, mègatutu wò ŋutigbalẽ sesĩe akpa o, ke ƒoe blewu.
• Do sox siwo me kɔ, siwo me mekɔ o kple afɔkpa: Do sox siwo me mekɔ o, siwo wotsɔ nusi le abe kotoklobo ene wɔe. Nenema kee wòle le afɔkpawo hã gome, eye le go geɖe me la, nane si le bɔbɔe abe afɔkpa ene ye nyo wu.

Nu vevitɔe nye be nàɖe asi kple afɔkpodzi dome masɔmasɔ dzi akpɔtɔ.

Ƒo asa na nusiawo wɔwɔ, hena ɣeyiɣi aɖe ya teti:

• Duƒuƒu: Elabena wò afɔkpodziwo le ƒoƒom ɖe anyigba ɣesiaɣi.
• Dɔ si wowɔ esime nèlé dɔwɔnuawo ɖe asi sesĩe:
• Lé hɛa sesĩe ne èle amagbewo lãm.
• Dɔwɔnuwo abe akplɔ kple akplɔ ene zazã ne èle dɔ wɔm le abɔ me.
• Aʋawɔnuwo zazã ne èle aƒeme dzadzraɖo wɔm (e.g. akplɔ léle esime nèle ɖa kum).
• Kpekpemewo kɔkɔ.

Nukae nye atike nyuitɔ kekeake na (Asi-Afɔ ƒe Dɔléle)?

Atike si me ʋeʋẽ lilili mele o, si me aha mele oTia. Aha ate ŋu ana ŋutigbalẽa naƒu ɖe edzi, si ate ŋu ana dzesiawo nagagblẽ ɖe edzi. Numekuku aɖewo ɖee fia be ne wotsɔ kreme si me urea 10% le zi etɔ̃ gbesiagbe la, ate ŋu akpe ɖe ŋutigbalẽa ŋu wòaɖe dzi ɖi eye wòana tsi nanɔ eŋu. Gake anyo wu be nàbia ɖɔkta hafi azã atike ɖesiaɖe.

Aleke gbegbee nye lãme ahaya kaba ne medzudzɔ atikewɔwɔ vɔ?

Esia ate ŋu ato vovo tso ame ɖeka gbɔ yi bubu gbɔ. Gake zi geɖe la, dzesi siawo nu yina vivivi le kwasiɖa eve va ɖo atɔ̃ me ne wodzudzɔ atikewɔmɔnu. Ate ŋu axɔ ŋkeke ʋɛ aɖewo hafi wòahaya keŋkeŋ.

Ðe mɔ aɖewo li siwo dzi woato axe mɔ ɖe Asi kple Afɔ ƒe Dɔléle nua?

Togbɔ be womate ŋu axe mɔ nɛ keŋkeŋ o hã la, nanewo li nàte ŋu awɔ atsɔ aɖe afɔkua dzi akpɔtɔ eye nàxe mɔ ɖe nɔnɔmea nu be wòagagblẽ ɖe edzi ne edzɔ o.

• Ne ŋutigbalẽ ƒe kuxi aɖewo le ŋuwò (e.g. ŋutigbalẽ ƒuƒu, ŋutigbalẽ si me gbagbã) la, nunya anɔ eme be nàna woadae hafi adze atikewɔmɔnu gɔme.
• Mɔ geɖe siwo dzi woato akpɔ dzesi siwo ŋu míeƒo nu tsoe va yi gbɔ hã kpena ɖe ame ŋu be woaxe mɔ ɖe (HFS) ƒe gɔmedzedze nu.
• Le kpɔɖeŋu me, ɖɔkta ate ŋu agblɔ na wò be nàzã tsilénu tso gbesigbe nèdze atikewɔmɔnu gɔme.
• Nusiwo nàte ŋu awɔ do ŋgɔ dometɔ aɖewoe nye be nàkpɔ wò ŋutigbalẽ ta tso dzoxɔxɔ me eye nàƒo asa na nuwɔna siwo ana wò asibidɛwo kple afɔkpodziwo nate ɖe ŋuwò madzemadzee eye nànɔ ʋuʋum.

Nukae ame si ŋu Asi-Afɔ ƒe Dɔléle'' le la tona?

Le nyateƒe me la, menye amesiamee Asi-Afɔ ƒe Dɔléle sia gblẽa nu le eŋu le mɔ ɖeka nu o. Ne wozã (chemotherapy) atike ɖeka ma ke hã la, alesi ame ɖeka sena le eɖokui me ate ŋu ato vovo kura tso alesi ame bubu sena le eɖokui me gbɔ. Le ame aɖewo gome la, ate ŋu anye fuɖename sue aɖe ko, evɔ le ame bubuwo gome la, ate ŋu asẽ ale gbegbe be wòahiã be woatrɔ woƒe kansadɔdamɔnu.

Akpa nyuitɔ kekeakee nye be, zi geɖe la, dzesi siawo nu yina ne wonya wu atikewɔmɔnu zazã nu ko . Ne èlé be na wò ŋutigbalẽ nyuie la, àte ŋu axe mɔ ɖe nusiwo agblẽ nu le ŋuwò ɣeyiɣi didi abe abixɔxɔ ene hã nu.

Ðe Asi kple Afɔ ƒe Dɔlélea ate ŋu ahe kuxi bubuwo vɛa?

Nu ɖekae nye be ame aɖewo ƒe asibidɛwo buna hena ɣeyiɣi aɖe. Esia ate ŋu anye fuɖename vie ɣeaɖewoɣi. Le kpɔɖeŋu me, ne èhiã asibidɛ ƒe dzesi ne èyi duta, abe ne èle mɔɖegbalẽ dim ene. Gake mègatsi dzi o, wò asibidɛwo agatsi le ɣleti ʋɛ aɖewo megbe ne wowu atikewɔwɔa nu.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Ele vevie ŋutɔ be nàna wò ɖɔkta nanya dzesi ɖesiaɖe si nàkpɔ esime nèle atikewo zãm, aleke kee wòɖale sue o. Vevietɔ la, kpɔ egbɔ be yegblɔe na wò ɖɔkta ne:

• Ne dzesiawo le dzidzim ɖe edzi vivivi.
• Ne ŋutigbalẽa gbã la, ke ŋutigbalẽa le ʋuʋum eye ʋu le dodom.
• Ne wò dzesiwo na wòsesẽna be nàwɔ wò gbesiagbedɔwo.

Le ɣeyiɣi siawo tɔgbe me la, ne ègblɔe na ɖɔkta la , ate ŋu ana atike si nèhiã la wò, alo atrɔ asi le wò atikewɔmɔnu ŋu.

Nya kawoe wòle be mabia ɖɔktaa?

Aɖe vi na wò ŋutɔ be nàbia wò ɖɔkta alo dɔnɔdzikpɔla nya siawo abe esiawo ene:

• Nu gbegblẽ kawoe mate ŋu akpɔ mɔ na ne mele atikewɔmɔnu zãm?
• Nu gbegblẽ kawoe wòle be mana nànya?
• Nu gbegblẽ kawoe wòle be makpɔ ɖɔkta alo ayi kɔdzi hena?
• Ðe nanewo li mate ŋu awɔ atsɔ axe mɔ ɖe eƒe nugbegblẽ le ame ŋu dometɔ aɖewo nua?
• Ðe atike tɔxɛ aɖewo li (abe lotions, creams) siwo nèkafu be woatsɔ axe mɔ ɖe Asi-Afɔ ƒe Dɔléle'' sia nu alo aɖu edzia?

Mlɔeba la, nusi dzi nàɖo ŋkui (Take-Home Message) .

Eyata, (chemotherapy) nye atike vevi aɖe ŋutɔ, si xɔa ame ɖe agbe na kansa. Ke hã, ele be míase egɔme hã be nugbegblẽ le ame ŋu siawo ate ŋu ado mo ɖa. (Asi-Afɔ ƒe Dɔléle) hã ​​nye nɔnɔme si bɔ, gake zi geɖe la, woate ŋu akpɔ egbɔ.

Ne dzesi siawo le ŋuwò la , mègatsi dzodzodzoe alo atsi dzodzodzoe o . Nu vevitɔe nye be nàƒo nu tso esia ŋu gaglãa kple wò lãmesẽnyawo gbɔ kpɔha. Woakpe ɖe ŋuwò nàkpɔ wò nɔnɔmea gbɔ eye nàwɔ tɔtrɔ le wò atikewɔwɔ ƒe ɖoɖoa ŋu ne ehiã. Menye wò ɖeka koe o, eye lãmesẽnyawo gbɔ kpɔha aɖe le asiwò si me ɖɔktawo, dɔnɔdzikpɔlawo, kple dɔwɔla bubuwo le be woakpe ɖe ŋuwò le mɔzɔzɔ sia me. Eyata, di woƒe kpekpeɖeŋu ne nane si ŋu nètsi dzi ɖo.