Ðe dɔgbo ƒe dɔléle dzea dziwò zi geɖea? Alo ɖe wò akɔta le bibim alo se le ɖokuiwò me le wò ŋɔti mea? Le ɣeyiɣi siawo tɔgbe me la, ezu numame na mía dometɔ geɖe be míano atike le atikedzraƒe. Zi geɖe la, atike ƒomevi si wozãna le mɔ sia nu enye Proton Pump Inhibitors, alo abe alesi míeyɔnae ene la, "gastritis medicine". Gake, ɖe míenya nusiwo tututu atike siawo nye, alesi wowɔa dɔe, kple ɣeyiɣi didi si wòle be woanoa? Egbea, míaƒo nu tso esia ŋu.
Nukae nye proton pɔmpi mɔxenu (PPI) siawo?
Kpuie ko la, esia nye atikewo ƒe hatsotso aɖe si ɖea acid, alo acid, si le wò dɔgbo me dzi kpɔtɔna. Fifia ɖewohĩ ànɔ eŋu bum be, "Ðe menyo be dɔgbo me acid nanɔ ame si oa?" Le nyateƒe me la, dɔgbo me acid nye nusi míate ŋu anɔ agbe manɔmee o. Ekpena ɖe mía ŋu míeɖua nuɖuɖu siwo míeɖuna eye wòwua dɔlékui gbegblẽ siwo gena ɖe nuɖuɖu me hã.
Gake kuxia dzea egɔme ne acid sia va sɔ gbɔ akpa, alo ne eyi afisi mele be wòanɔ o, abe wò nuɖuɖutome ene. Ɣemaɣie kuxiwo abe dzimeve kple dɔgbo ƒe abi ene dzea egɔme. Ɣemaɣie atike siawo siwo woyɔna be PPI va kpena ɖe mía ŋu.
Nɔnɔme vevi kawoe wotsɔa PPIwo daa dɔe?
Wozãa PPI-wo tsɔ daa nɔnɔme geɖe siwo do ƒome kple dɔgbo me acid. Na míalé ŋku ɖe vevitɔwo ŋu.
| Atikewɔwɔ ƒe nɔnɔme | Kpuie ko la, nusi dzɔnae nye |
|---|---|
| GERD / Acid ƒe Trɔtrɔ si nɔa anyi didi | Esiae míeyɔna zi geɖe be dzimeve. Dɔgbo me acid si yi dzi yi ɖe nuɖuɖutome ate ŋu agblẽ nu le nuɖuɖutome ŋu (erosive esophagitis) . PPI-tikewo ɖea dɔgbo me acid dzi kpɔtɔna eye wònaa nusiwo gblẽ la haya. |
| Peptic Ulcers (Dɔme kple Dɔgbo Sue ƒe Abi) . | Dɔgbo me acid ate ŋu agblẽ nu le dɔgboa alo dɔgbo suea ƒe ametakpɔnu ŋu, si ana abi nadze ame dzi. Abi siawo ate ŋu adze ame dzi hã ne woyi vevesesenutsitike aɖewo (NSAID) zazã dzi . PPI-tikewo ate ŋu akpe ɖe ame ŋu wòada abi siawo. |
| H. pylori ƒe dɔléle | Esia nye dɔlékui aɖe si hea dɔgbo ƒe abi vɛ. Wona PPI kpe ɖe dɔlékuiwutikewo ŋu be woatsɔ awu dɔlékui sia. Esia ɖea acid si le dɔgboa me dzi kpɔtɔna, si wɔnɛ be dɔlékuiwutikeawo wɔa dɔ nyuie wu. |
| Zollinger-Ellison ƒe dɔlélea | Esia nye nɔnɔme si mebɔ o. Dɔdzẽ aɖewo siwo le ŋutilãa me wɔa lãmetsi aɖe si nana dɔgboa wɔa acid fũ akpa. PPI-wo ate ŋu aɖu nɔnɔme sia dzi. |
Aleke atike sia wɔa dɔe?
Esia gɔmesese le bɔbɔe ŋutɔ. Tsɔe be ‘pɔmpi’ suesuesuewo le wò dɔgbo me siwo wɔa acid. Le dzɔdzɔmeŋutinunya nu la, woyɔa esiawo be hydrogen-potassium ATPase pɔmpiwo. Kpuie ko la, wonye "proton pɔmpiwo."
Fifia, nusi PPI-tike sia wɔnae nye be ‘wòxea mɔ na’ pɔmpi mawo siwo wɔa acid ƒe dɔwɔwɔ, si fia be etɔa wo. Ele abe tsi ƒe mɔ̃ ƒe ʋuƒoa tsitsi ene.
Gake esia mexea mɔ na acid ƒe wɔwɔme katã le dɔgboa me o. Ne èno PPI abe ŋkeke 5 ene ɖe wo nɔewo yome la, dɔgbo me acid ƒe wɔwɔ dzi aɖe akpɔtɔ abe 65% ene. 35% susɔea sɔ gbɔ be woatsɔ aɖu nuɖuɖu. Eyata naneke meli si ŋu woatsi dzi ɖo o.
PPI ƒomevi kawoe bɔ wu?
PPI ƒomevi vovovowo li. Woate ŋu aƒle ɖewo le atikedzraƒe (OTC) le atikedzraƒe ɖɔkta ƒe atikewɔmɔnu manɔmee, gake bubuwo ya hiã atikewɔmɔnu.
| Ŋkɔ Gbãtɔ | Adzɔnu ƒe Ŋkɔ Siwo Bɔ |
|---|---|
| Ƒomevi siwo li ne ɖɔkta ŋlɔe alo womeŋlɔe na wo o | |
| Esomeprazole ƒe atike | Nexium® ƒe dɔwɔwɔ |
| Lansoprazole ƒe atike | Prevacid® ƒe atike |
| Omeprazole ƒe atike | Prilosec® ƒe dɔwɔwɔ |
| Atikewɔlawo ƒe atikewɔmɔnu koe woate ŋu aƒle ƒomeviwo | |
| Dexlansoprazole ƒe atike | Dexilant® ƒe atike |
| Pantoprazole ƒe atike | Protonix® ƒe dɔwɔwɔ |
| Rabeprazole ƒe atike | AcipHex® ƒe ƒuƒoƒo |
Aleke wòle be woazã esiawoe?
Atike sia va le atikekui alo atikekui ƒe nɔnɔme me. Le amesiwo atikekui mimi sesẽna gome la, woate ŋu atsaka atikekui aɖewo kple nane abe akɔɖumi ene atsɔ axɔ atikekui la.
Nu vevitɔ kekeakee nye ɣeyiɣi si nàno atikeawo. PPI akpa gãtɔ wɔa dɔ wu ne wozãe le dɔgbo ƒuƒlu me . Zi geɖe la, wokafui be woanoe aɖabaƒoƒo 30 va ɖo gaƒoƒo ɖeka hafi aɖu ŋdinu. Nusitae nye be esia naa ɣeyiɣi atike la be wòaxɔ ɖe lãme eye wòadze dɔwɔwɔ gɔme, hafi dɔgboa me acid la naƒo ƒu le nuɖuɖu vɔ megbe.
Ga home nenie wòle be maƒle?
Esia nye nusi wò ɖɔkta atso nya me le godoo. Ame aɖewo ate ŋu ahiã atikekui ɖeka le ŋdi me. Woate ŋu agblɔ na ame bubuwo be woano ɖeka le ŋdi me eye woano ɖeka le zã me. Enɔ te ɖe wò atikewɔwɔ ƒe nɔnɔme dzi. Eyata ele vevie ŋutɔ be nàwɔ ɖe wò ɖɔkta ƒe mɔfiamewo dzi.
Ɣeyiɣi didi kae wòxɔna hafi PPI-wo wɔa dɔ?
Esia menye atike si naa gbɔdzɔe ame enumake o. Ate ŋu axɔ ŋkeke 1 va ɖo 4 hafi nàse atikeawo ƒe ŋusẽkpɔɖeamedzi bliboa.
Tsɔe be èɖu nuɖuɖu si me wodea nu ʋeʋĩiwoe eye kasia nèse dzobibi le wò akɔta. Le ɣeyiɣi mawo me la, antacid (e.g., Digene) alo histamine (H2) blocker (e.g., Famotidine) ate ŋu ana gbɔdzɔe kabakaba wu PPI. Gake woƒe ŋusẽkpɔɖeamedziwo nu yina kabakaba.
PPIs nye atike si naa nusiwo dona tso eme ɣeyiɣi didi, si sɔ nyuie wu na amesiwo ŋu acid si nɔa anyi didi ƒe kuxiwo le.
Ðe nusiawo ƒe nugbegblẽ le ame ŋu aɖewo lia?
Ame akpa gãtɔ mekpɔa nugbegblẽ aɖeke o, gake abe atike ɖesiaɖe ene la, ame aɖewo ate ŋu akpɔ nugbegblẽ suesuesuewo.
- Dɔgbo ƒe vevesese
- Miléle
- Dɔmetɔtrɔ
- Taɖuame
- Nu ƒuƒu
- Taɖuame
- Asrã
- Dɔgbo me yɔyɔ
- Ʋuʋudedi kple ʋuʋudedi
Afɔku siwo le eŋudɔwɔwɔ ɣeyiɣi didi me
Togbɔ be zi geɖe la, wobua PPI-tikewo be wonye atike siwo me afɔku mele o hã la, numekulawo de dzesi afɔku aɖewo siwo dona tso wo zazã ɣeyiɣi didi aɖe atikewɔlawo ƒe aɖaŋuɖoɖo aɖeke manɔmee .
- Clostridium difficile (C. diff) dɔlékui: Dɔlékui nyui kple vɔ̃ siwo le dɔgboa me ƒe dadasɔ trɔna, si wɔnɛ be aɖuɖɔtoe si me afɔku le dona.
- Gbagbãƒe: Ate ŋu ana wòasesẽ na ŋutilãa be wòaxɔ calcium, si ate ŋu ana akɔta, asibidɛ, alo akɔta ƒe gbagbã ƒe afɔkua nadzi ɖe edzi.
- Ayikudɔ: Ne wozãe ɣeyiɣi didi ate ŋu ana ayikudɔléle si nɔa anyi didi (CKD) xɔxɔ ƒe afɔkua nadzi ɖe edzi.
- Nunyiame ƒe veve: Ŋutilã ate ŋu aɖe magnesium kple vitamin B12 ƒe xɔxlɔ̃ dzi akpɔtɔ. Esiawo nye nunyiame veviwo na míaƒe lãmekawo kple lãmekawo.
Wogale nu srɔ̃m tso afɔku siawo ŋu kokoko, eyata zi geɖe la, ɖɔktawo dzea agbagba be yewoaɖu wò dzesiwo dzi to atike suetɔ kekeake nana wò hena ɣeyiɣi kpuitɔ kekeake .
Ɣekaɣie wòle be makpɔ ɖɔkta?
Ne ɖɔkta ŋlɔ PPI na wò la, ele be nàƒo nu kple wò ɖɔkta tso atikeawo dzudzɔ alo agbɔsɔsɔme tɔtrɔ ŋu.
Ne èle PPI siwo womeƒlena le atikedzraƒe o (OTC) zãm eye nèkpɔe be yehiã wo gbesiagbe be yeaɖu yeƒe dzesiwo dzi la, ele be nàkpɔ ɖɔkta godoo ale be woate ŋu akpɔ dɔlélea nyuie ahawɔ atike na ye.
Ne èkpɔ dzesi siwo gbɔna la, yi ɖɔkta gbɔ enumake:
| Dzesi si dzena | Nuɖᴐɖᴐ |
|---|---|
| Nusiwo ŋu nulɔdɔ le | Ŋutilã ƒe dzikudodo, ʋuʋudedi sesẽ, vuvu. |
| Dzesi siwo fia be ayiku gblẽ | Aɖuɖɔ si dona le lãme na ame dzi ɖe kpɔtɔ, asiwo, afɔkpodzi, alo afɔwo ƒe vuvu. |
| Dzesi siwo fia be magnesium ƒe agbɔsɔsɔ si mede ame dzi o | Ðeɖiteameŋu si gbɔ eme, dzi ƒe tsotso si mesɔ o, lãmekawo ƒe vevesese. |
| Vitamin B12 ƒe agbɔsɔsɔ si mede ame dzi o ƒe dzesiwo | Vevesese, lãmetutudɔ, taɖuame , tɔtɔ le abɔ alo afɔwo me. |
| Aɖuɖɔtoe alo dzoxɔxɔ sesẽ | Aɖuɖɔtoe alo dzoxɔxɔ si nɔa anyi ɖaa. |
Gbedasi si Wotsɔ Yi Aƒeme
- PPI-wo nye atike na acid ƒe kuxi siwo nɔa anyi didi, ke menye hena gbɔdzɔe enumake o.
- No wò atike ɣesiaɣi le ɣeyiɣi si nèɖo ɖi dzi (zi geɖe hafi nàɖu nu), abe alesi wò ɖɔkta gblɔe ene.
- Ƒo asa na PPI-tikewo zazã atraɖii hena ɣeyiɣi didi aɖe atikewɔlawo ƒe aɖaŋuɖoɖo manɔmee.
- Ne èhiã atike sia gbesiagbe alo ne eƒe nugbegblẽ aɖewo do mo ɖa la, kpɔ egbɔ be yeyi ɖɔkta gbɔ.
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Womeɖo nya aɖeke ɖe amewo haɖe o. Tsɔ wò nyaŋuɖoɖo kpe ɖe afisia zi gbãtɔ.
Tsɔ wò nyaŋuɖoɖo kpee