Wataƙila kun ji labarin magunguna kamar Viagra. Yawancin mutane sun san cewa waɗannan magunguna ne da ake bayarwa don rashin aikin jima'i. Amma shin kun san cewa ana amfani da magunguna a wani nau'i daban, mai suna Phosphodiesterase Inhibitors, don magance cututtuka daban-daban, tun daga cututtukan zuciya zuwa cututtukan huhu, cututtukan fata, da cututtukan gaɓoɓi? A yau, bari mu yi magana game da wannan nau'in magunguna masu ban mamaki. Bari mu fahimci menene su, yadda suke aiki, da kuma menene fa'idodi da rashin amfani.
A taƙaice dai, menene masu hana Phosphodiesterase (PDE inhibitors)?
Waɗannan nau'in magani ne da ke faɗaɗa jijiyoyin jini a jikinmu, yana rage taurinsu, kuma yana sauƙaƙa kwararar jini. Ka yi tunanin cewa idan bututun ruwa ya toshe, idan ka ƙara girmansa kaɗan, ruwan yana gudana cikin sauƙi. Wannan yana rage hawan jini kuma yana inganta kwararar jini zuwa sassa daban-daban na jiki. Saboda wannan ikon, ana amfani da wannan nau'in maganin a matsayin magani ga cututtuka daban-daban.
Yaya wannan maganin yake aiki?
Domin fahimtar wannan, da farko muna buƙatar sanin wani ƙaramin mai aika sinadarai a jikinmu. Sunansa Phosphodiesterases , ko PDE a takaice. Wannan PDE wani nau'in enzyme ne. Enzymes suna kama da ƙananan masu taimako waɗanda ke hanzarta da sauƙaƙe sauran hanyoyin sinadarai a jikinmu.
Akwai nau'ikan waɗannan enzymes na PDE da dama a jikinmu. Masana kimiyya sun yi amfani da lambobi don bambance su. Abu na musamman shi ne cewa kowane nau'in PDE yana aiki sosai a takamaiman sassan jiki.
- PDE-3: Wannan nau'in ana samunsa ne musamman a cikin zuciyarka da tsarin jijiyoyin jini . Hakanan yana da hannu a cikin tsarin zubar jini.
- PDE-4: Ana samun wannan galibi a cikin huhu . Yana aiki ta hanyar matse tsokoki a cikin hanyoyin iska.
- PDE-5: Ana samun wannan nau'in a cikin huhu da kuma al'aurar maza .
Don haka, magunguna da ake kira Phosphodiesterase Inhibitors (PDE inhibitors) suna aiki ta hanyar toshe ayyukan enzymes na PDE da aka ambata a sama. Kamar rufe ƙofa ne. Wasu magungunan hana PDE suna aiki sosai a zaɓe . Wato, suna kai hari ga wani takamaiman nau'i ne kawai, kamar PDE-5. Akwai wasu magunguna waɗanda ke aiki ba tare da zaɓe ba . Wato, suna iya shafar duk nau'ikan PDE zuwa wani mataki.
Wadanne yanayi ne ake magancewa da wannan maganin?
Hukumomi kamar Hukumar Abinci da Magunguna ta Amurka (FDA) sun amince da nau'in magungunan da ake kira PDE inhibitors don magance cututtuka sama da goma sha biyu. Ga wasu daga cikinsu.
| Rukunin cututtuka | Yanayin lafiya da bayani mai sauƙi |
|---|---|
| Zagayawar Zuciya da Jini |
|
| Cututtukan kumburi |
|
| Cututtukan tsarin haihuwa na maza |
|
| Cututtukan tsarin numfashi |
|
Menene fa'idodin PDE Inhibitors?
Wannan nau'in magani yana da matuƙar amfani wajen magance wasu matsalolin lafiya. Akwai dalilai da dama da suka sa hakan ya faru.
- Sauƙin amfani: Waɗannan magunguna suna zuwa ta hanyoyi daban-daban. Ana samun su a matsayin magungunan da ake sha ta baki, man shafawa na shafawa, da allurar IV. Wasu magunguna suna buƙatar a sha kowace rana, yayin da wasu kuma ana iya sha ne kawai idan ana buƙata.
- Maganin da aka yi niyya: Kamar yadda na ambata a baya, wasu magunguna suna yin niyya ne kawai ga wani takamaiman nau'in PDE, don haka ba sa haifar da illa da ba a so (tasirin illa) ga wasu sassan jiki. Kamar dai maganin yana aiki daidai inda cutar take.
- Amfani da dama na magani ɗaya: Wani lokaci cututtuka biyu masu alaƙa na iya faruwa a cikin mutum ɗaya. Misali, rashin lafiyar prostatic hyperplasia (BPH) da rashin lafiyar jima'i (ED) duka suna iya faruwa tare. An amince da maganin hana PDE-5 tadalafil don magance duka yanayin biyu. Hakazalika, akwai magunguna waɗanda za su iya magance gout da amosanin gabbai masu alaƙa.
Menene illa da haɗarin wannan maganin?
Abu mafi mahimmanci shine duk waɗannan magunguna ya kamata a sha su ne kawai bisa shawarar likita. Illar illa na iya bambanta daga magani zuwa magani da kuma daga mutum zuwa mutum.
Babban illar da ke tattare da maganin ya dogara ne akan nau'in maganin hana PDE.
| Nau'in Mai Hana PDE | Ƙananan illa da matsakaici | Illar da ka iya haifarwa mai tsanani (ka gaya wa likitanka nan take) |
|---|---|---|
| Masu hana PDE-3 (yana shafar zuciya da jijiyoyin jini) | Ciwon kai, rauni, kumburi, tashin zuciya, amai, ciwon ciki, jiri, kurajen fata. | Matsalolin bugun zuciya (arrhythmia), ciwon ƙirji, ƙarancin hawan jini, zubar jini ko ƙuraje, lalacewar hanta. |
| Masu hana PDE-4 (yana shafar huhu da kumburi) | Rage nauyi, tashin zuciya, amai, gudawa, cututtukan numfashi na sama, ciwon kai, rashin barci, kumburi a wurin allurar. | Ƙara ta'azzara damuwa da ke akwai, tunanin kashe kai, halayen rashin lafiyar jiki (ƙaiƙayi, kumburi, kurji). |
| Masu hana PDE-5 (yana shafar rashin ƙarfin jima'i da hawan jini na huhu) | Ciwon kai, kumburin hanci, toshewar hanci, ciwon baya, ciwon tsoka, tashin zuciya, jiri, da kuma yiwuwar ganin haske a launin shuɗi (na ɗan lokaci). | Priapism: Jinin da ke kawo cikas ga miji wanda ke ɗaukar fiye da awanni 4 ba tare da motsa jiki ta hanyar jima'i ba. Wannan gaggawa ce ta likita. Canje-canje/rashin gani ko ji kwatsam, lalacewar hanta. |
| Masu hana zaɓe marasa zaɓe (misali caffeine, theophylline) | Rashin natsuwa, rashin barci, rawar jiki, tashin zuciya, amai, gudawa, jiri, ciwon kai. | Saurin bugun zuciya, bugun zuciya mara tsari, ciwon ƙirji, farfadiya. |
Gargaɗi na Musamman: Idan kana shan magani kamar nitroglycerin a ƙarƙashin harshe don ciwon ƙirji, kuma ka kamu da ciwon ƙirji cikin awanni 24 bayan shan maganin hana PDE-5 (misali Sildenafil, Tadalafil), je ka je sashen gaggawa na asibiti (ETU) nan da nan. Haɗa waɗannan magunguna biyu na iya haifar da raguwar hawan jini mai haɗari.
Wa bai kamata ya sha wannan maganin ba?
Ga wasu mutane, wannan nau'in maganin da ake kira PDE inhibitors bazai dace ba saboda wasu matsalolin lafiya ko wasu magunguna da suke sha. Muna kiran waɗannan abubuwan hanawa . Akwai nau'i biyu daga cikinsu:
1. Cikakken contraindications:
- Ga duk wani maganin hana PDE: Idan kun taɓa samun mummunan rashin lafiyan (rashin lafiyar jiki) ga wannan maganin ko makamancin haka.
- Ga Cilostazol: Idan kana da wata irin matsalar zuciya.
- Ga masu hana PDE-5 (kamar Sildenafil, Tadalafil): cututtukan zuciya masu tsanani, ciwon ƙirji mara ƙarfi (angina mara ƙarfi), bugun zuciya ko bugun jini na baya-bayan nan.
2. Abubuwan da ba su dace ba game da amfani da shi:
- Ga masu hana PDE-5: Idan kuna shan nitrates ko alpha-blockers, ya kamata ku yi magana da likitanku domin suna iya sa hawan jininku ya ragu da haɗari.
- Ga Cilostazol: Idan kana da matsalar zubar jini.
- Don Pentoxifylline: Idan kwanan nan kun sami zubar jini a kwakwalwa ko ido.
Idan kina da juna biyu, ko kina ƙoƙarin yin ciki, ko kuma kina shayarwa, ki yi magana da likitanki kafin ki sha kowace magani. Akwai shaidar cewa wasu masu hana PDE na iya shafar tayin a binciken dabbobi.
Yaushe ya kamata ka ga likita?
Idan alamun cutar suka canza ko suka shafi ayyukanka na yau da kullun, ya fi kyau ka gaya wa likitanka. Amma, idan ka fuskanci ɗaya daga cikin waɗannan , ka je asibiti ko ɗakin gaggawa (ETU) nan da nan.
- Alamomin bugun zuciya: ciwon ƙirji, ƙarancin numfashi, gumi, jiri, tashin zuciya.
- Priapism: Jinin da ke haifar da tashin hankali wanda ke ɗaukar fiye da awanni 4 ba tare da motsa jiki ta hanyar jima'i ba. Wannan na iya haifar da lalacewa ta dindindin idan ba a yi maganinsa da wuri ba.
- Rashin gani ko ji kwatsam: Idan ka fuskanci asarar gani kwatsam, rashin gani, ko rashin ji, nemi taimakon likita nan da nan. Jinkiri na iya haifar da lalacewa ta dindindin.
Saƙon Ɗauka Gida
- Magungunan hana phosphodiesterase (PDE inhibitors) suna da matuƙar amfani wajen magance matsalolin jima'i, har ma da cututtukan zuciya, huhu, fata, da kuma gaɓɓai.
- Duk waɗannan magunguna ya kamata a sha su ne kawai bisa shawarar likita.Ka gaya wa likitanka game da duk wata cuta da kake da ita da kuma duk wata magani da kake sha.
- Illolin na iya faruwa, don haka a kula da su kafin a fara shan maganin.
- Idan ka fuskanci manyan alamu kamar ciwon ƙirji, ƙarancin numfashi na tsawon sama da awanni 4, ko kuma rashin gani/ji kwatsam, je zuwa Sashen Gaggawa (ETU) nan da nan.
- Amfani da wannan maganin ba tare da takardar likita ba, ta hanyar tambayar wasu ko kuma yin tambaya a shagunan magani, na iya haifar da mummunan sakamako, har ma da barazana ga rayuwa.
💬 අදහස් (0)
තවමත් කිසිදු අදහසක් පළ කර නොමැත. ඔබේ අදහස පළමු වරට මෙහි එක් කරන්න.
ඔබේ අදහස එක් කරන්න