ʻO ke kanaka e noho ana me ka maʻi Parkinson i kekahi manawa he mau manawa 'off' kahi e lilo koke ai ke kino i mea make, nalowale ka ikaika o nā lālā, a ʻaʻole hiki iā lākou ke neʻe pono. I loko o kēia mau manawa, manaʻo lākou he kōkua ʻole a ʻaʻole hiki ke hana i nā hana o kēlā me kēia lā. No laila, i kēia lā ke kamaʻilio nei mākou e pili ana i kahi lāʻau lapaʻau kūikawā e kōkua koke i ka hoʻomalu ʻana i kēlā manawa 'off' koke.
He aha kēia lāʻau lapaʻau i kapa ʻia ʻo Apomorphine?
I ka ʻōlelo maʻalahi, ʻo Apomorphine kahi lāʻau i hoʻohana ʻia e mālama i nā pae 'off' o ka maʻi Parkinson, ʻo ia hoʻi nā neʻe koke a paʻakikī. Loaʻa ia ma ke ʻano he ʻili lahilahi e hoʻoheheʻe ʻia ma lalo o ke alelo. He inoa kaulana ʻo KYNMOBI no kēia lāʻau.
E noʻonoʻo, aia i loko o ko kākou lolo kahi kemika kūikawā i kapa ʻia ʻo dopamine. ʻO kēia ka mea e kōkua iā kākou e kāohi i ka neʻe ʻana a me ka hoʻonohonoho ʻana o ko kākou kino. Hoʻemi ʻia ka pae o kēia dopamine i loko o ka lolo o kekahi kanaka me ka maʻi Parkinson. Hoʻonui ʻo Apomorphine i ka nui o ka dopamine i loko o ka lolo, e hōʻemi koke ana i nā hōʻailona e like me ka ʻoʻoleʻa, ka haʻalulu, a me nā neʻe lohi.
Nā mea e haʻi aku i kāu kauka ma mua o ka hoʻohana ʻana i kēia lāʻau lapaʻau
He mea nui loa e ʻike pono kāu kauka i kou kūlana olakino ma mua o ka hāʻawi ʻana iā ʻoe i kēia lāʻau lapaʻau. No laila, inā loaʻa iā ʻoe kekahi o kēia mau kūlana, e haʻi pono i kāu kauka e pili ana iā lākou.
| E ʻike inā loaʻa iā ʻoe kēia mau kūlana |
|---|
| Inā hiamoe koke ʻoe i ka wā e hana ana i nā hana o kēlā me kēia lā (e like me ke kamaʻilio ʻana, ka ʻai ʻana) |
| Inā pilikia ʻoe i ka kaohi ʻana i kou mau ʻiʻo |
| Inā loaʻa iā ʻoe kekahi ʻano maʻi puʻuwai, nā hewa o ka puʻuwai, a i ʻole nā loli i ka rhythm |
| Inā he haʻahaʻa kou koko |
| Inā loaʻa iā ʻoe ka maʻi puʻupaʻa a i ʻole ke akepaʻa |
| Inā loaʻa iā ʻoe nā pilikia hanu e like me ka maʻi māmā a i ʻole ka hānō |
| Inā ua loaʻa iā ʻoe kahi hahau |
| Inā loaʻa iā ʻoe kekahi ʻano maʻi noʻonoʻo |
| Inā loaʻa iā ʻoe ka apnea hiamoe |
| Inā he mea inu mau ʻoe |
| Inā he maʻi ʻaleka kou i ka apomorphine, sulfites, a i ʻole kekahi lāʻau lapaʻau ʻē aʻe, meaʻai, a mea hoʻoluʻu paha. |
| Inā hāpai ʻoe a i ʻole ke manaʻolana nei e hāpai |
| Inā he makuahine hānai ʻoe |
Pehea pololei kaʻu e hoʻohana ai i kēia lāʻau lapaʻau?
He mea maʻalahi loa kēia e hoʻohana, akā pono ʻoe e hahai pono i nā ʻōlelo aʻoaʻo.
1. E hoʻohana i kēia lāʻau lapaʻau ke hoʻomaka wale kahi kūlana 'Off' .
2. Pono e maloʻo loa kou mau lima ma mua o ka lawelawe ʻana i ka lāʻau lapaʻau.
3. E uhaʻi i ka ʻeke pepa kini i hoʻopaʻa ʻia me ka lāʻau lapaʻau a wehe pono i ka ʻili hoʻoheheʻe.
4. E kau i kēlā membrane ma lalo o kou alelo .
5. E hoʻoheheʻe iā ia iho. Mai ʻoki, kuʻi, a nau paha.
6. Mai hoʻohana ʻoi aku ma mua o ka nui i kauoha ʻia e ke kauka.
ʻO ka mea nui loa, mai hoʻōki i ka lawe ʻana i kēia lāʻau lapaʻau ke ʻole kāu kauka e haʻi aku iā ʻoe. ʻO ka hoʻōki koke ʻana iā ia hiki ke hoʻonui i kou kūlana a hoʻoulu i nā hopena ʻaoʻao koʻikoʻi.
He aha kāu e hana ai inā ʻoe e overdose ?
Inā manaʻo ʻoe ua lawe nui ʻoe i kēia lāʻau lapaʻau, e kelepona koke aku i ke Kikowaena ʻIke ʻAi Poisons ma ka Halemai Lahui ʻo Colombo, a i ʻole e hele i ka ʻOihana Hoʻopilikia (ETU) o ka haukapila kokoke loa. Ua kuhikuhi ʻia kēia lāʻau lapaʻau nou wale nō. Mai kaʻana like me nā poʻe ʻē aʻe.
He aha inā e hala wau i kahi lāʻau?
ʻAʻole kēia he lāʻau lapaʻau e pono e lawe ʻia i nā manawa he nui i ka lā. Hoʻohana wale ʻia ia ke loaʻa iā ʻoe kahi manawa 'off'. No laila, ʻaʻole pili ka manaʻo o ka nalo ʻana o kahi lāʻau ma aneʻi. Eia nō naʻe, inā ʻaʻole ʻoe e loaʻa ka hōʻoluʻolu mai kāu mau hōʻailona ma hope o ka hoʻohana ʻana i hoʻokahi kiʻiʻoniʻoni no kahi manawa 'off', mai hoʻohana i kahi kiʻiʻoniʻoni ʻē aʻe no kēlā manawa. E kamaʻilio me kāu kauka e pili ana i kēia.
Nā lāʻau lapaʻau ʻē aʻe e launa pū me kēia lāʻau lapaʻau
He lāʻau lapaʻau ʻo Apomorphine e hiki ke launa pū me kekahi mau lāʻau lapaʻau ʻē aʻe. No laila, he mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei (me nā huaora a me nā lāʻau lapaʻau lāʻau).
| Mai hoʻohana pū ʻoe i kēia mau lāʻau lapaʻau me ka lawe pū ʻana me Apomorphine. | |
|---|---|
| ʻO kekahi mau lāʻau lapaʻau no ka nausea/luaʻi (e.g., dolasetron, granisetron, ondansetron, palonosetron) | |
| ʻO Cisapride, Dronedarone, Pimozide, Thioridazine | |
| E makaʻala loa inā e lawe pū ana ʻo Apomorphine me kēia mau lāʻau lapaʻau. | |
| ʻAila | |
| Lāʻau lapaʻau no ka hopohopo a i ʻole ka hiamoe | |
| Nā lāʻau lapaʻau no ke koko, ka maʻi puʻuwai, a me nā maʻi puʻuwai | |
| Nā lāʻau ʻeha narcotic | |
| ʻO ka nitroglycerin | |
| ʻO Haloperidol, Metoclopramide, Phenothiazines (e like me chlorpromazine, prochlorperazine) | |
| Nā lāʻau lapaʻau ʻē aʻe e hoʻopilikia ai i ka puʻuwai puʻuwai (e hoʻolōʻihi i ka manawa QT) |
ʻAʻole i piha kēia papa inoa, no laila e haʻi pono i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei.
Nā mea e hoʻomanaʻo ai i ka wā e hoʻohana ai i kēia lāʻau lapaʻau
- Hiamoe a me ka poniuniu: Hiki iā ʻoe ke hiamoe a poniuniu paha. No laila , mai hoʻokele a hoʻohana paha i nā mīkini a hiki i kou ʻike ʻana i ke ʻano o kēia lāʻau lapaʻau iā ʻoe. Mai ala aʻe mai kahi noho a noho koke paha, ʻoiai inā he ʻelemakule ʻoe.
- Hiamoe koke: Hiki i kekahi poʻe ke hiamoe koke me ka ʻole o ka ʻōlelo aʻo ʻana i ka wā e lawe ana i kēia lāʻau. Hiki ke hana kēia i ka wā e hoʻokele ana, e kamaʻilio ana, a i ʻole e ʻai ana. Inā hana kēia iā ʻoe, e haʻi koke aku i kāu kauka.
- Nā makemake hiki ʻole ke kāohi ʻia: Ua hōʻike kekahi poʻe he makemake ikaika ko lākou e komo i nā hana e like me ka piliwaiwai, ka moekolohe, ka ʻai nui ʻana, a i ʻole ke kūʻai ʻana i ka wā e lawe ana i kēia lāʻau. Inā ʻike ʻoe i kekahi o kēia mau ʻano ʻē, e haʻi koke i kāu kauka.
- Ka luaʻi a me ka luaʻi: Hiki i kēia lāʻau lapaʻau ke hoʻoulu i ka luaʻi nui a me ka luaʻi. Hiki i kāu kauka ke kuhikuhi i kahi lāʻau lapaʻau ʻē aʻe e pale aku i kēia. Eia naʻe, ʻaʻole hiki ke hoʻohana ʻia nā lāʻau lapaʻau āpau no ka luaʻi me kēia lāʻau lapaʻau. No laila e nīnau i kāu kauka i ka lāʻau lapaʻau kūpono iā ʻoe.
- Ka Hoʻohana ʻana i ka Nitroglycerin: Inā ʻoe e lawe ana i ka Nitroglycerin, hiki ke hāʻule koke kou koko ke lawe ʻoe iā Apomorphine. No laila, inā ʻoe e lawe ana i kahi papa Nitroglycerin sublingual, he mea nui loa ia e moe i lalo ma mua a ma hope o ka lawe ʻana. Hiki i kēia ke kōkua i ka pale ʻana i ka poniuniu a me ka hāʻule ʻana.
He aha nā hopena ʻaoʻao e hiki ke loaʻa mai ka lāʻau lapaʻau?
| Nā hopena ʻaoʻao e pono ʻoe e hōʻike koke i kāu kauka |
|---|
| Nā hopena maʻi āpau - ka ʻili ʻana, ka ʻeha, ka pehu ʻana o ka maka, nā lehelehe, ke alelo a i ʻole ka puʻu |
| ʻEha umauma (Angina) - ʻeha, kaomi, a paʻa paha ma ka umauma, ʻāʻī, kua, a i ʻole nā lima |
| Ka huikau, nā hallucinations |
| Hiamoe koke ʻana i ka wā e hana ana i nā hana o kēlā me kēia lā |
| Nā loli i ka puʻuwai puʻuwai - ka puʻuwai wikiwiki a i ʻole ka puʻuwai kūpono ʻole, ka dizziness, ka nāwaliwali, ka ʻeha o ka umauma, ka paʻakikī o ka hanu ʻana |
| ʻO ka anemia hemolytic - ka luhi ʻole, ka nāwaliwali, ka dizziness, ka ʻeha poʻo, ka pōkole o ka hanu, ka mimi ʻeleʻele, ka melemele o ka ʻili a i ʻole nā maka |
| Ke koko haʻahaʻa - dizziness, nāwaliwali, ʻike maka pōʻeleʻele |
| Nā neʻe hou a hoʻonui paha i ka neʻe ʻana o ka maka, ka waha, a i ʻole ke kino o luna |
| ʻEha waha a ʻāʻī paha, ʻulaʻula, pehu, a me ka ʻeha |
| Ka pehu ʻana o nā kuʻekuʻe wāwae, nā lima, a i ʻole nā wāwae |
| ʻO ka hiki ʻana mai o nā makemake hiki ʻole ke kāohi ʻia i ʻōlelo ʻia ma luna (e like me ka piliwaiwai, ka ʻai nui ʻana) |
| Nā hopena ʻaoʻao e pono e hōʻike ʻia i ke kauka inā hoʻomau lākou a hoʻopilikia paha |
| Ka loli ʻana o ka ʻono i loko o ka waha |
| Hiamoe |
| ʻEha poʻo |
| Ka luaʻi |
| Ihu wai a i ʻole ka ihu paʻa |
Pehea ʻoe e mālama ai a hoʻolei aku i ka lāʻau lapaʻau?
- E mālama i kahi hiki ʻole i nā keiki a me nā holoholona ke kiʻi aku .
- E mālama i ka mahana o ka lumi maʻamau (ma waena o 20-25 kekelē Celsius).
- E mālama i loko o ka ʻeke i hoʻopaʻa ʻia a hiki i ka wā e hoʻohana ai.
- E nīnau i kāu kauka e pili ana i ke ala palekana loa e hoʻolei aku ai i nā lāʻau lapaʻau i pau ka lā a i ʻole nā lāʻau lapaʻau e pono ʻole ai.
Leka Lawe-Home
- ʻO ka ʻili ʻili Apomorphine sublingual kahi lāʻau lapaʻau i hāʻawi ʻia no nā hanana 'off' koke o ka maʻi Parkinson, ʻaʻole ia he lāʻau lapaʻau i kēlā me kēia lā.
- E hoʻomaloʻo i kou mau lima i ka wā e hoʻohana ai i kēia, e kau ma lalo o kou alelo a e hoʻoheheʻe. Mai nau a wili paha.
- Hiki i kēia lāʻau lapaʻau ke hoʻohiamoe iā ʻoe, no laila e makaʻala loa i ka hana ʻana i nā hana e pono ai ka noʻonoʻo ʻana, ʻoiai i ka wā e hoʻokele ana.
- Inā loaʻa iā ʻoe nā makemake hiki ʻole ke kāohi ʻia a i ʻole nā hopena koʻikoʻi ʻē aʻe, e haʻi koke i kāu kauka.
- He mea nui loa e hoʻomaopopo i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei.
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