Ua kuhikuhi anei kāu kauka iā Venetoclax no kahi maʻi kanesa? Inā pēlā, he mea nui loa ia e hoʻomaopopo piha ʻia e pili ana i kēia lāʻau lapaʻau. No ka mea, he lāʻau lapaʻau ikaika loa kēia a kūikawā hoʻi. I kēia lā, e kamaʻilio maʻalahi a akahai mākou e pili ana i ke ʻano o kēia lāʻau lapaʻau a me nā mea e pono ai ʻoe e makaʻala i ka wā e hoʻohana ai.
He aha ke ʻano lāʻau lapaʻau kēia? (He aha ʻo Venetoclax?)
I ka ʻōlelo maʻalahi, ʻo Venetoclax kahi "lāʻau lapaʻau i kuhikuhi ʻia." ʻO ke ʻano kēia, ua kuhikuhi akamai loa kēia lāʻau i nā protein kikoʻī i loko o nā hunaola kanesa, e hoʻōki ana a pepehi paha iā lākou mai ka ulu ʻana. Hana ia ma ke ʻano ʻokoʻa ma mua o ka chemotherapy maʻamau.
Hoʻohana nui ʻia kēia lāʻau lapaʻau e mālama i nā maʻi ʻaʻai e pili ana i ke koko e like me:
- ʻO ka maʻi leukemia lymphocytic mau loa (CLL)
- ʻO ka Lymphoma Lymphocytic liʻiliʻi (SLL)
- ʻO ka maʻi leukemia myelogenous koʻikoʻi (AML)
Hiki i kāu kauka ke ʻōlelo aku i kēia lāʻau lapaʻau no nā kūlana olakino ʻē aʻe.
Nā mea e pono ai ʻoe e haʻi i kāu kauka ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau
Ma mua o ka hoʻomaka ʻana iā Venetoclax, he mea nui loa ia e hāʻawi i kāu kauka i kahi wehewehe piha o kou kūlana olakino. E hōʻoia e haʻi i kāu kauka inā loaʻa iā ʻoe kekahi o kēia mau kūlana:
- Maʻi puʻupaʻa a maʻi akepaʻa paha: Inā loaʻa iā ʻoe kekahi maʻi puʻupaʻa a maʻi akepaʻa paha.
- Nā ʻano ʻino o ke koko: Inā kiʻekiʻe ka nui o ka waikawa uric i loko o ke koko, a inā haʻahaʻa a kiʻekiʻe paha nā pae o nā paʻakai e like me ka potassium, phosphorus, a me ka calcium.
- Gout: Inā he gout kou.
- Inā ua hoʻonohonoho ʻia ʻoe e loaʻa i kahi lāʻau pale: Inā ʻoe e hoʻolālā nei e loaʻa koke i kahi lāʻau pale, ʻoiai hoʻi kahi lāʻau pale ola.
- Nā maʻi ʻaleka: Inā he maʻi ʻaleka kou iā Venetoclax a i ʻole kekahi lāʻau lapaʻau ʻē aʻe, meaʻai, a mea hoʻoluʻu paha.
- Hāpai: Inā hāpai ʻoe, e hoʻāʻo ana e hāpai, a manaʻo paha ua hāpai ʻoe.
- Inā he makuahine hānai ʻoe: Inā ʻoe e hānai waiū ana i kāu pēpē.
Ma muli o kēia ʻike, e hoʻoholo kāu kauka i ka nui o ka lāʻau lapaʻau e hāʻawi ʻia iā ʻoe, ke ʻano o ka lawelawe ʻana, a me nā hana palekana āu e pono ai e hana.
Pehea pololei kaʻu e hoʻohana ai i kēia lāʻau lapaʻau?
He ʻāpana koʻikoʻi loa kēia. E hahai i kēia mau kuhikuhi e loaʻa ai ka pono nui o ka lāʻau lapaʻau a hōʻemi i nā hopena ʻaoʻao.
- E lawe me ka meaʻai: E lawe mau i kēia papa me ka ʻai a me ke aniani wai. Mai lawe i ka ʻōpū ʻole.
- E ale i ka papa: Mai uhaʻi, kuʻi, a nau paha i ka papa. E ale holoʻokoʻa.
- Mai ʻai i kēia mau huaʻai: Mai inu i ka wai pomelo, ʻai i nā ʻalani Seville, a i ʻole starfruit i ka wā e lawe ana i kēia lāʻau. Hiki i kēia ke hoʻololi i ke ʻano o ka hana ʻana o ka lāʻau i loko o ke kino.
- E lawe i ka manawa kūpono: E ho'āʻo e lawe i kāu lāʻau lapaʻau i ka manawa like i kēlā me kēia lā. Mai lawe ʻoi aku ma mua o ka nui i kauoha ʻia e kāu kauka.
- Mai ho'ōki i ka lawe ʻana i kāu lāʻau lapaʻau me ka ʻole o ke aʻo ʻana a kāu kauka no kekahi kumu .
E hoʻomanaʻo, ua kuhikuhi ʻia kēia lāʻau lapaʻau nou wale nō. Mai kaʻana like me kekahi.
He aha kāu e hana ai inā e hala ʻoe i kahi manawa hoʻopaʻa lāʻau lapaʻau?
E noʻonoʻo ʻoe ua poina iā ʻoe e lawe i kāu lāʻau lapaʻau.
- Inā ʻoi aku ma mua o 8 mau hola mai kou lawe hope ʻana i ka pila i kou hoʻomanaʻo ʻana, e lawe koke iā ia i ka wā e hoʻomanaʻo ai ʻoe.
- Eia nō naʻe, inā ua hala ma mua o 8 mau hola mai kou lawe hope ʻana i kahi lāʻau, e hōʻalo i ka lāʻau i hala ʻole. E lawe i kāu pila i kou manawa maʻamau i ka lā aʻe.
- Mai lawe i ka lāʻau pālua.
- Inā ʻoe e luaʻi ma hope o ka lawe ʻana i ka lāʻau lapaʻau, mai lawe hou i kahi pila. E lawe i ka mahele maʻamau i ka manawa i hoʻonohonoho ʻia i ka lā aʻe.
Nā mea e pono e makaʻala nui ʻia i ka wā e lawe ai iā Venetoclax
Pono ʻoe e makaʻala iki aku i kou kino i ka wā e lawe ana i kēia lāʻau.
- Ka Pōpilikia o ka Tumor Lysis Syndrome (TLS): He ʻano paʻakikī kēia huaʻōlelo, akā he maʻalahi ia: Ke luku koke ʻo Venetoclax i nā hunaola kanesa, e kahe koke ana nā mea o loko o kēlā mau hunaola i loko o ke koko. Hiki i kēia ke hoʻopilikia i nā puʻupaʻa. E kuhikuhi paha kāu kauka i nā lāʻau lapaʻau ʻē aʻe ma mua o kou hoʻomaka ʻana e lawe i ka lāʻau e pale aku i kēia.
- E inu i ka wai nui: ʻO kekahi o nā ala maikaʻi loa e hōʻemi ai i ka pilikia o TLS, ʻo ia ka inu ʻana i ka wai nui i ka lā a pau. Pono ʻoe e inu i ka nui o ka wai a kāu kauka e ʻōlelo ai (ʻo ka maʻamau he 1.5 - 2 lita i ka lā).
- Nā hoʻāʻo koko: ʻOiai e lawe ana i kēia lāʻau lapaʻau, e kauoha kāu kauka i nā hoʻāʻo koko e nānā i kāu helu koko a me ka hana o nā puʻupaʻa i nā manawa a pau. Mai haʻalele i kēia mau hoʻāʻo.
- E pale iā ʻoe iho mai nā maʻi: Hiki i kēia lāʻau lapaʻau ke hoʻohaʻahaʻa i ka pale ʻana o kou kino. ʻO ia hoʻi, ʻoi aku ka nui o kou maʻi. No laila e noho mamao aku mai ka poʻe i loaʻa i ke kuni a i ʻole ke anu. Inā loaʻa iā ʻoe nā hōʻailona e like me ke kuni, ke kuni, a i ʻole ka ʻeha o ka puʻu, mai hoʻōla ponoʻī a e hoʻomaopopo koke i kāu kauka .
- Hāpai a me ka hānai waiū: Mai hāpai i ka wā e lawe ana i kēia lāʻau lapaʻau a no 30 mau lā ma hope o ka hoʻōki ʻana. Eia kekahi, mai hāpai i ka wā e lawe ana i ka lāʻau lapaʻau a no hoʻokahi pule ma hope o ka hoʻōki ʻana.E pale i ka hānai waiū . E nīnau i kāu kauka no ka ʻike hou aku e pili ana i kēia.
He aha nā hopena ʻaoʻao e hiki ke loaʻa mai kēia lāʻau lapaʻau?
E like me nā lāʻau lapaʻau āpau, hiki iā Venetoclax ke hana i kekahi mau hopena ʻaoʻao. He koʻikoʻi kekahi o kēia mau mea, aʻo kekahi he mea maʻamau. ʻO ka mea nui, ʻo ia ka makaʻala i kēia mau hōʻailona a hana koke inā pono.
| Ka hopena ʻaoʻao/hōʻailona | Wehewehena |
|---|---|
| E hele koke aku i kāu kauka a i ʻole ke Keʻena Pilikia (ETU) o ka haukapila. | |
| Nā hopena aleri koʻikoʻi | ʻŌhūhū ʻili, maneʻo, pehu o ka maka, lehelehe a i ʻole ke alelo, paʻakikī ke hanu. |
| Nā hōʻailona o ka maʻi lysis tumor (TLS) | Luaʻi/nalu, paʻakikī ka hanu ʻana, puʻuwai kūpono ʻole, mimi ʻeleʻele, luhi nui, ʻeha ʻiʻo a hui paha. |
| Nā hōʻailona o ka maʻi | Kuni, anu, ʻū mau, ʻeha ka puʻu, wela i ka wā e mimi ai. |
| Nā hōʻailona o ke kahe ʻana o ke koko | ʻO ka ʻōpala ʻeleʻele a koko paha, ka mimi ʻulaʻula a ʻeleʻele paha, ka luaʻi e like me ke kofe lepo, nā kiko ʻulaʻula ma ka ʻili, ke kahe koko ʻokoʻa mai ka ihu a i ʻole nā ʻāʻī. |
| Inā hoʻomau a lilo paha i mea hoʻopilikia, e hoʻomaopopo i kāu kauka. | |
| Nā hopena ʻaoʻao maʻamau | Ka maʻi kahe, ka paʻa ʻana o ka ʻōpū, ka ʻeha kua, ka ʻeha poʻo, ka poniuniu, ka pehu ʻana o nā kuʻekuʻe wāwae a me nā wāwae. |
Inā loaʻa iā ʻoe kekahi mau hōʻailona ʻē aʻe i ʻōlelo ʻole ʻia ma kēia papa inoa, e kamaʻilio pū me kāu kauka e pili ana iā lākou.
Nā mea ʻē aʻe e launa pū me kēia lāʻau lapaʻau
Hiki iā Venetoclax ke launa pū me nā lāʻau lapaʻau ʻē aʻe, nā lāʻau lapaʻau lāʻau, a me kekahi mau meaʻai. No laila e haʻi i kāu kauka e pili ana i nā mea āpau āu e lawe nei - me nā lāʻau lapaʻau i kauoha ʻia, nā lāʻau lapaʻau ma luna o ke kūʻai aku, nā huaora, nā lāʻau lapaʻau lāʻau, a me nā mea hoʻohui. He mea nui loa ia e haʻi i kāu kauka inā ʻoe e lawe ana i kekahi o kēia mau lāʻau lapaʻau:
- Nā lāʻau lapaʻau antifungal (e.g. Ketoconazole, Fluconazole)
- Kekahi mau lāʻau antibiotic (e.g. Clarithromycin, Erythromycin)
- ʻO kekahi mau lāʻau lapaʻau no ke koko kiʻekiʻe a me nā maʻi puʻuwai (e like me Diltiazem, Verapamil, Carvedilol)
- Nā lāʻau lapaʻau anticonvulsant (e.g. Carbamazepine, Phenytoin)
- Nā huahana lāʻau lapaʻau e like me ka wort ʻo St. John
- Nā lāʻau pale ola
ʻAʻole i piha kēia papa inoa, no laila ʻoi aku ka palekana o ka haʻi ʻana i kāu kauka e pili ana i nā mea āpau āu e lawe nei.
Pehea ʻoe e mālama ai a hoʻolei aku i ka lāʻau lapaʻau?
- Ka Mālama ʻana: E mālama ʻia mai ka hiki ʻana aku o nā keiki a me nā holoholona. E mālama i loko o ka pahu kumu, pani paʻa ʻia, mai ka makū a me ka wela nui, ma ka mahana o ka lumi (ma lalo o 30 degere Celsius).
- Ka Hoʻolei ʻana: ʻO ke ala palekana loa e hoʻolei aku ai i nā lāʻau lapaʻau i pau ka manawa a i ʻole makemake ʻole ʻia, ʻo ia ka lawe ʻana iā lākou i kahi papahana lawe lāʻau lapaʻau ma kāu haukapila a hale kūʻai lāʻau paha. Inā ʻaʻole hiki kēlā, e wehe i nā pila mai ka ʻōmole, e kāwili iā lākou me kahi mea e like me ke kope kope i hoʻohana ʻia, ka ʻōpala pōpoki, a i ʻole ka lepo, e hoʻokomo iā lākou i loko o kahi ʻeke sila, a hoʻolei iā lākou i loko o ka ʻōpala. Mai hoʻolei iā lākou i lalo o ka lua.
Leka Lawe-Home
- E lawe mau i nā papa Venetoclax me ka ʻai a me ke aniani wai. Mai wāwahi, kuʻi, a nau paha i ka papa.
- E hōʻalo i ka ʻai ʻana a inu ʻana paha i ka huaʻala, nā ʻalani Seville, a me nā kumquats i ka wā e lawe ana i kēia lāʻau.
- E inu i ka wai he nui i ka lā a pau, e like me ka ʻōlelo a kāu kauka. He mea nui loa kēia.
- E haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe, nā huaora, a me nā lāʻau lapaʻau āu e lawe nei.
- E ʻimi koke i ke kōkua lapaʻau inā loaʻa iā ʻoe nā hōʻailona o ka maʻi a i ʻole nā hōʻailona o TLS, e like me ke kuni a me ke anu.
- Mai ho'ōki i ka lawe ʻana i ka lāʻau lapaʻau me ka ʻole o ke aʻoaʻo lapaʻau no kekahi kumu.
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