Ua kuhikuhi anei kāu kauka iā Vorinostat nou a i ʻole kekahi o kou ʻohana? ʻOiai he lāʻau lapaʻau kūikawā kēia i hoʻohana ʻia no ka mālama ʻana i ka maʻi kanesa, loaʻa paha iā ʻoe nā nīnau, ka hoihoi, a me ka makaʻu iki paha. He mea maʻamau kēlā. Mai hopohopo. Ma kēia ʻatikala, e kamaʻilio mākou e pili ana i kēia lāʻau lapaʻau, kāna hana, a me nā mea āu e pono ai e makaʻala.
He aha ke ʻano lāʻau lapaʻau ʻo Vorinostat?
I ka ʻōlelo maʻalahi, he lāʻau chemotherapy ʻo Vorinostat. Akā, ʻaʻole ia e like me ka lāʻau kanesa a mākou e loaʻa mau ai ma ka haukapila me ka saline. He capsule ia āu e lawe ai ma ka waha.
Hoʻohana kūikawā ʻia kēia lāʻau lapaʻau e mālama i kahi ʻano maʻi kanesa e kū mai ana i ka ʻili i kapa ʻia ʻo cutaneous T-cell lymphoma (CTCL) . He mea paʻakikī paha ke kani ʻana, akā he ʻano maʻi kanesa wale nō ia e hoʻopilikia ai i ka ʻili. E kuhikuhi pinepine kāu kauka i kēia lāʻau lapaʻau ma lalo o ka inoa inoa ʻo Zolinza.
Nā mea e pono ai ʻoe e haʻi i kāu kauka ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau
Ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau, he mea nui loa ia e kūkākūkā i kāu mōʻaukala olakino piha me kāu kauka. ʻO kēia no ka mea pono kekahi mau kūlana olakino i ka mālama kūikawā i ka wā e hoʻohana ai i kēia lāʻau lapaʻau. Ma ke ʻano kūikawā, e hōʻoia e haʻi i kāu kauka inā loaʻa iā ʻoe:
- Inā loaʻa iā ʻoe ka maʻi diabetes
- Inā he moʻolelo kou o nā ʻōpū koko
- Inā he mau nīnau kāu e pili ana i nā puʻuwai puʻuwai kūpono ʻole
- Inā loaʻa iā ʻoe ka maʻi akepaʻa
- Inā ʻoe e lawe ana i nā lāʻau lapaʻau ʻē aʻe e pale ai a mālama paha i nā ʻōpū koko (e like me warfarin)
- Inā ua loaʻa iā ʻoe kahi hopena maʻi i Vorinostat a i ʻole kekahi lāʻau lapaʻau ʻē aʻe, meaʻai, a mea hoʻoluʻu paha.
- Inā ʻoe e ho'āʻo nei e hāpai a ua hāpai mua paha
- Inā hānai waiū ka makuahine i kāna keiki
Pehea e hoʻohana pono ai i ka lāʻau lapaʻau?
He mea nui loa ke ʻano o kāu hoʻohana ʻana i kēia lāʻau. E like me ka ʻōlelo a ke kauka, ʻo ka lawe ʻana iā ia i ka manawa kūpono ke ala maikaʻi loa e loaʻa ai nā hopena maikaʻi loa.
- He capsule kēia e pono e lawe ʻia me ke aniani wai.
- He mea nui loa ka lawe ʻana i kēia lāʻau lapaʻau me ka ʻai . E hōʻemi kēia i ka pilikia o ka ʻōpū ʻeha.
- Mai nau, wili, a wehe paha i ke kāpule a inu i ka pauka i loko. Pono e ale ʻia ke kāpule me ka ʻole o ka hoʻoponopono.
- Mai inu ʻoe ma mua o ka mea a ke kauka e ʻōlelo ai iā ʻoe, a mai hoʻōki a hiki i kona ʻōlelo ʻana iā ʻoe e hoʻōki.
He aha inā wau e lawe i ka overdose?
E noʻonoʻo ua lawe hewa ʻoe ma mua o ka nui i kuhikuhi ʻia. Inā hana ʻia kēia, mai hopohopo a e hele koke i ka haukapila kokoke loa ʻo Emergency Department (ETU) . A i ʻoleE kelepona i ke Kikowaena ʻIke Lāʻau Make ma ka Halemai Lahui ʻo Colombo no ka ʻōlelo aʻo.
He aha inā poina iaʻu e lawe i kaʻu lāʻau lapaʻau?
He aha kāu e hana ai inā poina iā ʻoe ke lawe i kāu lāʻau lapaʻau? E lawe i ka lāʻau i hala koke i kou hoʻomanaʻo ʻana. Eia nō naʻe, inā kokoke ka manawa no kāu lāʻau aʻe, e kāpae i ka lāʻau i hala a lawe i ka lāʻau aʻe i ka manawa i hoʻonohonoho ʻia. Mai lawe i ʻelua lāʻau i ka manawa hoʻokahi (lāʻau pālua).
He lāʻau lapaʻau kēia i kuhikuhi ʻia nou wale nō. Mai hāʻawi i kēia lāʻau lapaʻau i kekahi no kekahi kumu.
Nā lāʻau lapaʻau ʻē aʻe e launa pū me kēia lāʻau lapaʻau
Hiki iā Vorinostat ke hana i nā hopena weliweli ke lawe ʻia me kekahi mau lāʻau lapaʻau ʻē aʻe. No laila, he mea nui loa e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei (me nā huaora, nā huahana lāʻau lapaʻau, a me nā lāʻau hoʻomaha ʻeha).
ʻAʻole pono e lawe pū ʻia nā lāʻau lapaʻau me Vorinostat:
* cisapride
* dronedarone
* pimozide
* thioridazine
Eia kekahi, aia kekahi mau lāʻau lapaʻau ʻē aʻe e hiki ke launa pū me kēia. No laila, inā ʻoe e lawe ana i kekahi o kēia mau lāʻau lapaʻau, e hoʻomaopopo i kāu kauka:
- ʻO kekahi ʻano lāʻau antibiotic: e like me 'clarithromycin', 'erythromycin', 'levofloxacin', 'mefloquine'.
- Nā lāʻau lapaʻau no ke kaumaha, ka hopohopo, a i ʻole nā maʻi noʻonoʻo ʻē aʻe.
- Nā lāʻau lapaʻau no nā maʻi o ka puʻuwai.
- Nā lāʻau lapaʻau e like me ka valproic acid (kahi lāʻau lapaʻau no ka hopu ʻana ).
- Nā lāʻau lapaʻau e pale ai i ke kāpili ʻana o ke koko: e like me `warfarin`, `enoxaparin`, `heparin`.
- Nā lāʻau lapaʻau ʻē aʻe no ke kanesa: e like me `dasatinib`, `lapatinib`.
- Nā lāʻau lapaʻau ʻē aʻe e hoʻopilikia ai i ka helu o ka puʻuwai (e hoʻolōʻihi i ka manawa QT).
ʻAʻole i piha kēia papa inoa. No laila e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe ai, inā ʻoe e puhipaka, a inā ʻoe e inu waiʻona.
Nā mea kūikawā e makaʻala ai i ka wā e lawe ai i ka lāʻau lapaʻau
Aia kekahi mau mea āu e makaʻala nui ai i ka wā e lawe ana i kēia lāʻau.
- Nā Hoʻāʻo Koko: He mea nui e loaʻa nā hoʻāʻo koko maʻamau e like me ke kauoha a kāu kauka i ka wā e lawe ana i kēia lāʻau. E kōkua kēia i ka nānā ʻana i ke ʻano o ka hopena o ka lāʻau i kou kino, ʻoiai kou mau pae potassium a me ka magnesium a me nā hunaola koko.
- E inu i ka wai nui: E inu i ka wai nui i ka lā a pau. He mea nui loa ia e pale aku i ka maloʻo ʻana o ka wai. E nīnau i kāu kauka e pili ana i ka nui o ka wai āu e inu ai i kēlā me kēia lā.
- Nā capsules lāʻau lapaʻau me ke akahele:Inā haki kahi capsule lāʻau lapaʻau a i ʻole e ninini ʻia ka pauka i loko, mai hoʻopā i ka pauka a i ʻole e hoʻopili iā ia me kou mau maka a i ʻole ka ʻili. Inā haki, e holoi koke i ka wahi me ke kopa a me ka wai. Inā komo i loko o kou mau maka, e holoi pono me ka wai a kāhea koke aku i ke kauka.
- ʻO ka hāpai ʻana a me ka hānai waiū: He mea hopohopo nui kēia.
- Inā he wahine ʻoe, e pale i ka hāpai ʻana i ka wā e lawe ana i kēia lāʻau lapaʻau a no ka liʻiliʻi he 6 mau mahina ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau.
- Inā he kāne ʻoe, mai hānau i keiki i ka wā e lawe ana i kēia lāʻau lapaʻau a no ka liʻiliʻi he 3 mau mahina ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau.
- Hiki i kēia lāʻau lapaʻau ke hōʻeha nui i kahi pēpē i hānau ʻole ʻia. E nīnau i kāu kauka no ka ʻike hou aku e pili ana i kēia.
- Inā he makuahine hānai ʻoe, mai hānai i kāu pēpē i ka waiū umauma i ka wā e lawe ana i kēia lāʻau lapaʻau a no hoʻokahi pule ma hope o ka hoʻōki ʻana.
- Ka hānau keiki: Hiki i kēia lāʻau lapaʻau ke hoʻopilikia i kou hānau keiki. Inā he mau hopohopo kāu e pili ana i kēia, e kamaʻilio me kāu kauka ma mua o ka hoʻomaka ʻana i ka lāʻau.
Nā hopena ʻaoʻao e hiki mai ana ma muli o ka lāʻau lapaʻau
E like me nā lāʻau lapaʻau āpau, hiki iā Vorinostat ke hana i nā hopena ʻaoʻao. He koʻikoʻi kekahi, a he akahai kekahi. ʻO ka mea nui loa, ʻo ia ka makaʻala i kēia mau hōʻailona a haʻi koke i kāu kauka inā loaʻa iā ʻoe kekahi.
| ʻAno o ka hopena ʻaoʻao | Nā ʻano |
|---|---|
| Nā hōʻailona koʻikoʻi e pono ai ke kuhikuhi koke ʻana i kāu kauka a i ʻole ka ʻOihana Hoʻopilikia (ETU) | |
| Nā hopena alerika | ʻŌhūhū ʻili, maneʻo nui, pehu o ka maka, nā lehelehe a i ʻole ke alelo. |
| Nā hōʻailona o ka pilikia hanu a me nā maʻi puʻuwai | Paʻakikī ka hanu ʻana, ʻeha ka umauma, ka puʻuwai wikiwiki a ʻano ʻole paha. |
| Nā hōʻailona o nā ʻōpū koko | ʻEha, pehu, a me ka ʻulaʻula ma ka wāwae (pinepine hoʻokahi wāwae). |
| Nā hōʻailona koʻikoʻi ʻē aʻe | Luli, luaʻi, kuni, anu, ʻeha ka ʻāʻī, kahe koko a ʻeha paha, luhi nui, paʻakikī i ka hele a kamaʻilio paha, pehu ma nā wāwae. |
| Nā hōʻailona maʻamau e pono e hōʻike ʻia i ke kauka inā hoʻomau a hoʻopilikia paha lākou | |
| Nā pilikia o ka ʻōnaehana hoʻoheheʻe | Ka maʻi pākīkī, ka paʻa ʻana o ka ʻōpū, ka nausea, ka luaʻi ʻana, ka ʻeha ʻōpū. |
| Nā ʻano laulā ʻē aʻe | Ka loli ʻana o ka ʻono, ka waha maloʻo, ka ʻeha poʻo, ka nele o ka makemake e ʻai, ka ʻeha o nā ʻiʻo. |
Pehea e mālama pono ai i ka lāʻau lapaʻau?
- E hoʻopaʻa i nā lāʻau lapaʻau a waiho ʻole ʻia mai ka ʻike a ka poʻe keiki liʻiliʻi .
- E mālama ma ka mahana o ka lumi (ma waena o 15 a me 30 kekelē Celsius). Mai mālama ma nā wahi haʻahaʻa kiʻekiʻe, e like me ka lua.
- E hoʻolei i ka lāʻau lapaʻau i pau me ka hoʻohana ʻole ʻana.
Leka Lawe-Home
- He lāʻau lapaʻau ʻo Vorinostat i hoʻohana ʻia e mālama i kahi ʻano maʻi kanesa i kapa ʻia ʻo CTCL. E lawe mau i kēia e like me ke kuhikuhi a kāu kauka.
- E haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe ai a me nā kūlana olakino āpau āu e loaʻa nei.
- E ale i ka lāʻau lapaʻau me ka ʻai. Mai nau, kuʻi, a wehe paha i ke capsule.
- Pono e akahele i ka wā e hoʻohana ai i kēia lāʻau lapaʻau i ka wā hāpai, hānai waiū, a inā ʻoe e kali ana i kahi pēpē. E hahai i nā ʻōlelo a kāu kauka.
- E ʻimi koke i ke kōkua lapaʻau inā loaʻa iā ʻoe nā hopena koʻikoʻi e like me ka paʻakikī o ka hanu ʻana, ka ʻeha o ka umauma, a i ʻole ke kahe koko ʻana.
- Inā he mau hopohopo a nīnau paha kāu, mai makaʻu e kamaʻilio me kāu kauka. ʻO kou kuleana ke nīnau e pili ana i kou olakino.
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