Ke hopohopo mau nei ʻoe e pili ana i kāu cholesterol? Ua kauoha paha kāu kauka i kahi hoʻāʻo koko e nānā i kāu cholesterol. Ma waho aʻe o ka hoʻāʻo lipid profile maʻamau, ʻōlelo pinepine nā kauka i kahi hoʻāʻo kūikawā e nānā hohonu i kou pilikia o ka maʻi puʻuwai. ʻO kekahi o ia mau hoʻāʻo ʻo ia ka hoʻāʻo ApoB. Hiki i kēia ke hāʻawi iā ʻoe i kahi kiʻi maopopo loa inā paha ʻoe i ka pilikia no ka maʻi puʻuwai.
He aha maoli ka Apolipoprotein B?
I ka ʻōlelo maʻalahi, ʻo ka apolipoprotein B-100, a i ʻole ApoB no ka pōkole, he protein e kōkua i ka lawe ʻana i ka momona a me ka cholesterol ma loko o ko mākou kino.
E noʻonoʻo i kēia ʻano. He mea nui ka momona a me ka cholesterol no ka mālama ʻana i nā ʻāpana o ko kākou kino i ke olakino a me ka hana ʻana i nā hormones. Akā ʻo ka pilikia, ʻaʻole hoʻi e hoʻoheheʻe ʻia kekahi o lākou i loko o ke koko. Ua like ia me ke kau ʻana i ka ʻaila i loko o ka wai. No laila, pono mākou i kahi 'pūʻolo' kūikawā e lawe iā lākou i nā ʻāpana āpau o ke kino. ʻO kēlā pūʻolo ka mea a mākou e kapa nei he lipoprotein . Aia ka protein ApoB ma ke kua o kēia pūʻolo lipoprotein a hana ma ke ʻano he 'mea hoʻokele' e lawe ana iā ia.
ʻO ka mea nui loa, pili ka protein ApoB me nā ʻano lipoproteins i hōʻino i ko mākou kino, ka mea i kapa ʻia ʻo "cholesterol maikaʻi ʻole." Hiki i kēia mau mea ke kūkulu i loko o ko mākou mau kīʻaha koko, e pani ana iā lākou a alakaʻi i nā maʻi puʻuwai.
| Nā ʻano lipoproteins "maikaʻi ʻole" i lawe ʻia e ka protein ApoB | |
|---|---|
| Nā lipoproteins haʻahaʻa loa | Nā lipoproteins haʻahaʻa loa (VLDL) |
| Nā lipoproteins haʻahaʻa haʻahaʻa | Nā lipoproteins haʻahaʻa haʻahaʻa (LDL) |
| Nā lipoproteins waena-density | Nā lipoproteins density waena (IDL) |
Hoʻopili ka protein ApoB i nā ʻāpana o ko kākou kino a kōkua i ka pūʻolo lipoprotein e komo i loko o ke ʻāpana. A laila wāwahi ʻia, e hoʻokuʻu ana i ka momona a me ka cholesterol i loko o ke koko. Ke piʻi ka nui o kēia cholesterol maikaʻi ʻole, hoʻomaka ia e waiho i loko o nā kīʻaha koko.
No ke aha e pono ai iaʻu e hana i kēia hoʻāʻo ApoB-100?
He liʻiliʻi loa ka cholesterol lipoprotein haʻahaʻa (LDL) i loko o ke koko o ke kanaka olakino. Akā, ʻo ka hoʻonui ʻia o kēlā nui e hoʻonui ai i ka pilikia o ka maʻi puʻuwai. ʻO ka mea nui, aia i loko o kēlā me kēia ʻāpana cholesterol maikaʻi ʻole hoʻokahi protein ApoB.
ʻO ia hoʻi, inā hiki iā mākou ke ana i ka nui o ka protein ApoB, hiki iā ia ke hāʻawi iā mākou i kahi kiʻi pololei loa o ka nui o nā ʻāpana cholesterol maikaʻi ʻole i loko o ko mākou koko. I kekahi manawa hiki i kēia ke hāʻawi iā mākou i kahi kiʻi pololei ma mua o ke ana ʻana i ko mākou pae cholesterol LDL awelika.
Aia kekahi mau kumu e hiki ai i kāu kauka ke ʻōlelo i kēia hoʻokolohua:
- Inā loaʻa i kekahi o kou ʻohana ka maʻi puʻuwai .
- Inā ua ʻike mua ʻia ʻoe me ka maʻi puʻuwai .
- E nānā i ka holomua o nā lāʻau lapaʻau no nā maʻi puʻuwai.
- Inā ua loaʻa iā ʻoe nā pae kiʻekiʻe o ka cholesterol a i ʻole triglycerides .
I ka manawa pinepine, e kauoha pū kāu kauka i kahi panela lipid maʻamau me ka hoʻāʻo ApoB. Ana kēia i nā mea e like me nā pae cholesterol, nā pae triglyceride, ka cholesterol "maikaʻi" (HDL), a me ka cholesterol "maikaʻi ʻole" (LDL). Hoʻohui ʻia kēia mau hōʻike ʻelua e hāʻawi i kahi loiloi piha o kou pilikia maʻi puʻuwai.
Pehea ʻoe e hana ai i kēia hoʻāʻo?
He maʻalahi loa ia. He hoʻāʻo koko maʻalahi ka hoʻāʻo ApoB. Ma ka lab, lawe kahi kahu maʻi a loea paha i kahi koko liʻiliʻi mai kahi aa koko ma kou lima.
Akā e hoʻomanaʻo, inā ua kauoha kāu kauka i nā hoʻokolohua ʻē aʻe, e like me ka panela lipid, e noi ʻia paha ʻoe e hoʻokē ʻai no kahi o 12 mau hola . ʻO ke ʻano kēia, ʻaʻole ʻoe e ʻai a inu paha i kekahi mea ʻē aʻe ma mua o ka wai no 12 mau hola ma mua o ka hoʻokolohua. E aʻo aku kāu kauka iā ʻoe e pili ana i kēia ma mua.
He aha ka ʻōlelo a ka hōʻike hoʻāʻo?
Hoʻohana pinepine ʻia nā waiwai ApoB ma nā milligrams no ka deciliter (mg/dL).
| Hopena | Manaʻo a me nā kumu kūpono |
|---|---|
| Waiwai maʻamau (Ma lalo o 90 mg/dL) | Aia nā lipoproteins maikaʻi ʻole i loko o kou koko ma kahi pae olakino. Haʻahaʻa ka pilikia o ka maʻi puʻuwai. |
| Waiwai kiʻekiʻe (Kiʻekiʻe) (ʻoi aku ma mua o 110 mg/dL) | Loaʻa iā ʻoe kahi pilikia kiʻekiʻe ma mua o ka awelika o ka loaʻa ʻana o ka maʻi puʻuwai. Hiki paha kēia ma muli o:
|
| Waiwai haʻahaʻa (Haʻahaʻa) | Hiki ke hana ʻia kēia e kekahi mau pilikia olakino. ʻAʻole hiki paha i ke kino ke hana pono i nā lipoproteins. |
I kekahi manawa, e hoʻohālikelike kāu kauka i kāu pae ApoB (maikaʻi ʻole) me kāu ApoA (ka protein e lawe ana i ka cholesterol maikaʻi). Inā ʻoi aku ke kiʻekiʻe o kāu ApoB ma mua o kāu ApoA, he hōʻailona nō hoʻi ia o ka hoʻonui ʻia o ka maʻi puʻuwai.
Aia kekahi mau kumu ʻē aʻe e loli ai nā waiwai i loko o ka hōʻike?
ʻAe, ʻoiaʻiʻo nō. Ma waho aʻe o nā kūlana olakino i ʻōlelo ʻia ma luna, hiki i kekahi mau lāʻau lapaʻau āu e lawe ai a me nā mea e pili ana i ke ʻano o ka nohona ke hoʻopilikia i kāu mau pae ApoB.
- Nā ʻano o nā hormones (Androgens, Estrogens)
- Nā lāʻau lapaʻau koko kiʻekiʻe e like me nā beta-blockers
- Nā lāʻau lapaʻau
- Lāʻau lapaʻau thyroid
- ʻO Statins, kahi ʻano lāʻau hoʻohaʻahaʻa cholesterol
- Ke hana ʻoki kino nei
- Ka emi ʻana o ke kaumaha a i ʻole ka loaʻa ʻana o ke kaumaha
- ʻAi momona kiʻekiʻe
- ʻO kekahi mau huaora a me nā mea hoʻopihapiha āu e lawe ai
No laila, ma mua o ka hana ʻana i kēia hoʻokolohua, he mea nui e hoʻomaopopo i kāu kauka e pili ana i kēlā me kēia lāʻau lapaʻau, nā huaora, a me nā mea hoʻohui āu e lawe nei.
Eia kekahi, e hoʻomanaʻo he ʻokoʻa iki paha kēia mau waiwai maʻamau ma muli o nā labs like ʻole, ke ʻano i hoʻohana ʻia, kou makahiki, ke kāne, a me ka mōʻaukala olakino. No laila, no ka ʻike pono ʻana i ke ʻano o kāu hōʻike, e kamaʻilio me kāu kauka. E wehewehe pono ʻo ia iā ʻoe.
Leka Lawe-Home
- ʻO ApoB kahi protein e lawe ana i nā ʻāpana "cholesterol maikaʻi ʻole" (LDL, VLDL) i loko o ko mākou kino.
- Hiki i ka hoʻāʻo ApoB ke ana pololei i ka nui o nā ʻāpana cholesterol ʻino i loko o ke koko. He mea nui loa kēia no ka loiloi ʻana i ka pilikia o ka maʻi puʻuwai.
- ʻO nā pae ApoB kiʻekiʻe he hōʻailona ia o ka piʻi ʻana o ka maʻi puʻuwai. Eia nō naʻe, hiki i nā pae haʻahaʻa ke hōʻike i nā pilikia olakino ʻē aʻe.
- Hiki i nā lāʻau lapaʻau āu e lawe ai a me kou nohona ke hoʻopilikia i nā hopena o kēia hoʻokolohua.
- ʻO kāu kauka ke kanaka maikaʻi loa a ʻo ke kanaka hoʻokahi wale nō e kamaʻilio pū ai e pili ana i ke ʻano maoli o kāu hōʻike hoʻāʻo a me nā hana aʻe e hana ai.
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