Ke melemele nei kou mau maka? He maʻi Gilbert paha ia!

Ua manaʻo paha ʻoe e like me ke melemele iki nei ke keʻokeʻo o kou mau maka a me kou ʻili? He mea weliweli iki ka ʻike ʻana i kēlā, ʻeā? Manaʻo paha ʻoe he ʻano maʻi akepaʻa ia. ʻO kekahi kumu paha o kēia, he ʻano i kapa ʻia ʻo Gilbert's syndrome. Akā, mai makaʻu i kou lohe ʻana i ka inoa, ʻaʻole ia he mea weliweli e like me kou manaʻo. ʻO ka ʻoiaʻiʻo, ʻoi aku ia he ʻano maʻi genetic ma mua o kahi maʻi.

I ka ʻōlelo maʻalahi, he aha ka Gilbert's syndrome?

He maʻi maʻamau loa ka maʻi Gilbert e holo ana i loko o ko kākou mau ʻohana, ʻo ia hoʻi, he mea hoʻoilina ia. ʻO ke kanaka me kēia, he nui loa ka huahana ʻōpala i kapa ʻia ʻo bilirubin i loko o ko lākou koko.

I kēia manawa, ke noʻonoʻo nei paha ʻoe i ke ʻano o ka bilirubin. He mea maʻalahi loa ia. He ola ko nā hunaola koko ʻulaʻula i loko o ko kākou kino. Ke pau kēlā ola, e haki lākou. He pigment melemele ʻo Bilirubin, a he huahana ʻōpala paha, i hana ʻia i ka wā e haki ai nā hunaola koko ʻulaʻula. ʻO ka maʻamau, lawe ko kākou ake i kēia bilirubin, hana iā ia, a lawe aku mai ke kino ma o ka bile.

Akā i loko o ka poʻe me ka maʻi Gilbert, ʻaʻole lawa ka hana ʻana o ke akepaʻa i kahi enzyme kūikawā e hana i kēia hana. No laila, ʻaʻole hiki ke hoʻomaʻemaʻe loa ʻia ka bilirubin, a koe kekahi o ia mea i loko o ke koko. Ke piʻi ka pae bilirubin i loko o ke koko, i kekahi manawa e melemele nā ​​maka a me ka ʻili. Kāhea pū mākou i kēia he jaundice .

He aha ke kumu o kēia kūlana?

Ma muli kēia o kahi ʻokoʻa liʻiliʻi i loko o kā mākou mau genes. E like me kā mākou hoʻoilina ʻana i nā mea e like me ke kala o ka ʻili a me ke ʻano o ka lauoho mai ko mākou mau mākua mai, he ʻoiaʻiʻo nō hoʻi kēia.

Aia kekahi gene i loko o ko kākou kino i kapa ʻia ʻo UGT1A1 . Ke kuhikuhi mai nei kēia gene iā kākou e hana i ka enzyme akepaʻa aʻu i ʻōlelo ai ma mua e hoʻomaʻemaʻe i ka bilirubin. Hoʻokumu ʻia ka maʻi Gilbert e kahi mutation liʻiliʻi i loko o kēia gene.

I mea e loaʻa ai kēia maʻi iā ʻoe, pono ʻoe e loaʻa i ʻelua kope o ka gene i hoʻololi ʻia. ʻO ke ʻano kēia, pono ʻoe e hoʻoilina i ka gene mai kou makuahine a me kou makuakāne . Eia nō naʻe, inā loaʻa iā ʻoe nā gene ʻelua, ʻaʻole e hōʻike nā kānaka a pau i nā hōʻailona o ka maʻi Gilbert. Eia kekahi, ʻoi aku ka maʻamau o ke ʻano i nā kāne ma mua o nā wahine.

He aha nā hōʻailona o ka Gilbert's syndrome?

ʻO kaʻoiaʻiʻo, ʻo ka hapa nui o ka poʻe me ka maʻi Gilbert ʻaʻohe o lākou hōʻailona . Loaʻa iā lākou nā enzymes ate e kaohi i nā pae bilirubin i loko o ko lākou kino.

ʻO ka hōʻailona nui a i kekahi manawa wale nō ka melemele o nā keʻokeʻo o nā maka a me ka ʻili, i ʻike ʻia ʻo jaundice. Inā ʻike ʻoe i ka melemele o nā maka, he mea nui e ʻike i ke kauka no ka nānā ʻana , no ka mea, aia paha nā kumu ʻē aʻe.

Hiki i kekahi poʻe ke ʻike i nā hōʻailona e like me ka melemele o nā maka:

• Ka luaʻi ʻana a me ka ʻeha o ka ʻōpū
• ʻO ka ʻeha o ka ʻōpū
• Manaʻo luhi loa (fatigue)
• Mimi ʻeleʻele

No ke aha e melemele ai koʻu mau maka i kekahi manawa wale nō, ʻaʻole i nā manawa a pau?

He nīnau maikaʻi kēia. Aia kekahi mau mea e hiki ai ke hoʻonui i ko mākou pae bilirubin. ʻO kēia ka manawa e ʻike pinepine ai mākou i ka melemele o nā maka.

Pehea e ʻike ai i kēia maʻi?

ʻOiai he maʻi hānau ʻia ka maʻi Gilbert, ʻike pinepine ʻia ia i ka poʻe i ko lākou mau makahiki 20 a 30 paha. Hana ʻia kēlā ma ka ulia pōpilikia.

E noʻonoʻo ʻoe e loaʻa ana iā ʻoe kahi hoʻāʻo koko no kekahi kumu ʻē aʻe. A laila ʻike kāu kauka ua ʻoi aku ka kiʻekiʻe o ka pae bilirubin i loko o kou koko ma mua o ka maʻamau. A laila manaʻo paha ʻo ia he maʻi Gilbert kou.

A laila, i mea e hōʻoia ai ʻaʻohe maʻi ʻino ʻē aʻe o ke akepaʻa, hiki i ke kauka ke hana i kekahi mau hoʻokolohua, e like me:

• Nā Hoʻāʻo Hana Ake (LFT): He hoʻāʻo koko maʻamau kēia.
• ʻIke Ultrasound o ke akepaʻa: No ka nānā ʻana i nā pilikia ʻē aʻe o ke akepaʻa.
• Nā Hoʻāʻo Gene: E hōʻoia inā loaʻa iā ʻoe ka mutation gene UGT1A1.
• ʻO ka Biopsy o ke Ake: Hana kākaʻikahi ʻia kēia.

ʻO ka mālama ʻana a me nā mea hiki iā mākou ke hana iā mākou iho

ʻO ka nūhou maikaʻi, ʻo ka hapa nui o ka poʻe me ka maʻi Gilbert ʻaʻole pono lākou i kekahi lāʻau lapaʻau , a ʻo ka melemele o kou mau maka ʻaʻole ia e hoʻopilikia iā ʻoe i ka wā lōʻihi.

No laila, ʻo ka mea e pono ai mākou e hana, ʻo ia ke noho mamao loa aku mai nā mea aʻu i ʻōlelo ai ma mua e hoʻonui ai i nā pae bilirubin.

• Mai hōʻalo i ka ʻai ʻana, ʻoiai hoʻi i ka wā e hoʻokē ʻai ai.
• E inu i ka nui o ka wai a me nā wai. Mai hoʻokuʻu i kou kino e maloʻo.
• E hoʻokele i ke kaumaha. E hana i kahi mea hoʻomaha e like me ka noʻonoʻo ʻana, ka hoʻolohe ʻana i ke mele, a i ʻole ke komo ʻana i kahi hana leʻaleʻa āu e makemake ai.
• Moe maikaʻi. E hiamoe ma ka liʻiliʻi he 7-8 mau hola i ka lā.
• E hōʻemi a hoʻōki loa paha i ka inu ʻana i ka waiʻona .
• E pale i ka hoʻoikaika kino ikaika. Maikaʻi ka hoʻoikaika kino kaulike, akā, mai koi iā ʻoe iho ma mua o kou palena.

He aha kāu e pono ai e ʻike i ka wā e lawe ai i ka lāʻau lapaʻau!

He mea nui loa kēia. Inā loaʻa iā ʻoe ka maʻi Gilbert, pono ʻoe e makaʻala i kēia ma mua o ka lawe ʻana i kekahi lāʻau lapaʻau hou.

ʻO ka enzyme like e hoʻomaʻemaʻe ana i ka bilirubin i loko o ko kākou akepaʻa e kōkua pū ana i ka wāwahi a wehe ʻana i kekahi mau lāʻau lapaʻau mai ke kino. No laila, no ka mea, he maʻi Gilbert kou, ua emi iki ka hana o kēlā enzyme. No laila, inā ʻoe e lawe i ia mau lāʻau lapaʻau, hōʻiliʻili nui lākou i loko o ke kino.Kiʻekiʻe ka pilikia o nā hopena ʻaoʻao.

Eia kekahi laʻana, e nānā i kēia mau lāʻau lapaʻau:

• ʻAsetaminopena - (Loaʻa iā Panadol, Paracetamol)
• ʻO Irinotecan - kahi lāʻau lapaʻau i hoʻohana ʻia e mālama i ka maʻi kanesa
• ʻO kekahi mau lāʻau lapaʻau no ka maʻi HIV a me ka hepatitis C (Protease inhibitors)