Nej yuav tsum tau hnov peb cov niam, txiv, pog, thiab yawg hais tias, "Auj, kuv lub cev tsis muaj zog tam sim no," thiab "Kuv cov pob txha tsis khov." Qhov tseeb, thaum peb laus zuj zus, peb lub cev lub zog txo qis, thiab lub zog ntawm peb cov pob txha maj mam txo qis. Qee zaum, thaum qhov mob no hnyav zuj zus, txawm tias poob me ntsis lossis txawm tias sawv ntawm txaj tuaj yeem ua rau muaj kev pheej hmoo siab heev ntawm kev tawg caj npab lossis ceg. Qhov mob no uas cov pob txha tsis muaj zog thiab tawg yog hu ua osteoporosis . Yog li, hnub no peb yuav tham txog ib pawg tshuaj tseem ceeb heev uas cov kws kho mob siv los tswj hom pob txha tsis muaj zog no.
Hais yooj yim xwb, cov bisphosphonates no yog dab tsi?
Bisphosphonates yog ib hom tshuaj siv los kho cov mob xws li osteoporosis uas txo cov pob txha ceev thiab lub zog. Qhov no txhais tau tias tsis muaj ib hom tshuaj nrog lub npe no, tab sis yog kev sib xyaw ua ke ntawm ntau hom tshuaj. Ntxiv rau osteoporosis, cov kws kho mob kuj sau cov tshuaj no rau qee kis uas muaj cov calcium ntau hauv cov ntshav (hypercalcemia).
Cia peb saib cov hom tshuaj tseem ceeb hauv pawg no. Cov no muaj ob hom tshuaj tseem ceeb. Ib hom yog noj (tshuaj noj los ntawm qhov ncauj), thiab lwm hom yog txhaj rau hauv cov hlab ntsha (IV) (kua uas muab rau hauv cov hlab ntsha).
| Yuav muab tshuaj li cas | Piv txwv ntawm cov tshuaj (feem ntau siv hauv Sri Lanka) |
|---|---|
| Cov tshuaj Bisphosphonates hauv qhov ncauj | Alendronate, Risedronate, Ibandronate |
| Cov kua dej hauv cov hlab ntsha (IV Bisphosphonates) | Zoledronic acid, Pamidronate |
Cov tshuaj no cuam tshuam li cas rau lub cev?
Yuav kom nkag siab qhov no, peb yuav tsum xub nkag siab me ntsis txog seb peb cov pob txha ua haujlwm li cas. Xav txog peb cov pob txha zoo li lub tsev uas kho tas li. Peb lub cev ib txwm tawg thiab tshem tawm cov pob txha qub thiab tsis muaj zog. Cov txheej txheem no hu ua pob txha resorption.Tib lub sijhawm ntawd, cov pob txha tshiab thiab muaj zog dua tau tsim nyob rau hauv cov cheeb tsam uas nws tau raug tshem tawm. Tsuav yog ob txoj kev no sib npaug, peb cov pob txha tseem muaj zog.
Txawm li cas los xij, thaum peb laus zuj zus, tshwj xeeb tshaj yog tom qab lub sijhawm tas sij hawm ntawm cov poj niam, qhov sib npaug no ploj mus. Qhov tshwm sim yog tias cov pob txha qub raug rhuav tshem sai dua li cov pob txha tshiab tsim. Qhov tshwm sim yog tias cov pob txha maj mam nyias dua, muaj qhov ntau dua, thiab qaug zog dua.
Yog li, cov bisphosphonates no ua yog tswj thiab txo qhov nrawm ntawm kev rov qab pob txha. Tom qab ntawd, vim tias cov pob txha qub muaj zog thaum cov pob txha tshiab tab tom tsim, qhov ceev thiab lub zog ntawm cov pob txha nce ntxiv. Hais yooj yim, lawv tiv thaiv kev poob pob txha.
Cov tshuaj bisphosphonates siv rau cov mob twg?
Cov kws kho mob feem ntau pom zoo kom siv cov tshuaj no rau cov mob hauv qab no:
- Mob pob txha tawg yog ib yam mob uas tshwm sim rau cov poj niam tom qab lub cev tsis muaj zog lawm.
- Kab mob pob txha hauv cov txiv neej.
- Txhawm rau tiv thaiv qhov tshwm sim ntawm osteoporosis.
- Kab mob pob txha tawg uas tshwm sim los ntawm kev siv cov tshuaj xws li steroids (glucocorticoids).
- Kab mob Paget ntawm pob txha yog ib yam kab mob uas cov pob txha loj hlob tsis zoo.
- Tswj cov teeb meem uas tshwm sim nrog qee hom mob qog noj ntshav (piv txwv li Multiple Myeloma) thiab thaum cov hlwb qog noj ntshav kis mus rau cov pob txha (Bone Metastasis).
- Txhawm rau tswj cov kab mob qog noj ntshav hypercalcemia (cov calcium ntau ntxiv hauv cov ntshav vim yog mob qog noj ntshav).
Kuv yuav tsum siv cov tshuaj no li cas? Qhov no tseem ceeb heev!
Nws yog ib qho tseem ceeb uas yuav tsum ua raws li cov lus qhia no kom tau txais txiaj ntsig tag nrho ntawm cov tshuaj thiab txo cov kev mob tshwm sim.
Cov Tshuaj Noj
Txoj kev noj cov tshuaj no yog ib txoj kev tshwj xeeb heev. Koj yuav tsum ua raws li tus kws kho mob cov lus qhia kom meej.
- Yuav tsum noj cov tshuaj thaum sawv ntxov, ua ntej noj mov lossis haus dej dab tsi (thaum lub plab khoob) .
- Cov tshuaj no tsuas yog noj nrog ib khob dej puv nkaus (dej dawb) . Txwv tsis pub noj cov tshuaj no nrog cov khoom xws li tshuaj yej, kas fes, mis nyuj, lossis dej txiv hmab txiv ntoo.
- Qhov tseem ceeb tshaj plaws: Tom qab noj tshuaj, koj yuav tsum zaum lossis sawv ntsug tsawg kawg yog 30 txog 60 feeb . Tsis txhob khoov, pw, lossis pw tsaug zog rau txhua yam laj thawj.
- Qhov laj thawj rau qhov no yog vim tias cov tshuaj no tuaj yeem ua rau lub caj pas puas tsuaj. Qhov kev pheej hmoo ntawd raug tshem tawm thaum koj sawv ntsug vim tias cov tshuaj hla mus rau hauv lub plab sai sai.
- Nws tsis yog lub tswv yim zoo los noj lossis haus lwm yam dab tsi thaum lub sijhawm 30-60 feeb no. Tom qab lub sijhawm ntawd tas, koj tuaj yeem noj tshais li niaj zaus.
Cov Tshuaj IV
Koj ua tsis tau qhov no hauv tsev. Kev kho mob no yog muab rau hauv tsev kho mob lossis chaw kho mob. Nyob ntawm koj tus mob, feem ntau yuav muab tshuaj txhaj (infusion) no ib xyoos ib zaug lossis txhua ob peb lub hlis.
Thaum noj cov tshuaj no, koj tus kws kho mob feem ntau yuav pom zoo kom koj noj cov khoom noj uas muaj calcium ntau (mis nyuj, mis nyuj yogurt, cheese, ntses me) thiab noj cov tshuaj vitamin D ntxiv , vim ob qho tib si tseem ceeb rau cov pob txha muaj zog.
Cov kev mob tshwm sim ntawm bisphosphonates yog dab tsi?
Ib yam li lwm yam tshuaj, tej zaum yuav muaj qee qhov kev phiv. Tab sis tsis txhob txhawj, feem ntau ntawm lawv yog me me xwb.
| Hom tshuaj | Tej zaum yuav muaj tej yam tshwm sim tsis zoo |
|---|---|
| Tshuaj noj | Cov teeb meem ntawm txoj hnyuv xws li mob plab, GERD, mob caj pas, mob plab, thiab mob qog. (Cov no feem ntau yuav tiv thaiv tau los ntawm kev ua raws li txoj kev noj koj cov tshuaj kom raug.) |
| Tshuaj txhaj rau hauv cov hlab ntsha (IV) | Tej yam tsos mob zoo ib yam li mob khaub thuas lossis mob ntsws xws li kub taub hau, mob lub cev, mob taub hau, thiab mob pob qij txha thiab mob nqaij, yuav tshwm sim li ib lossis ob hnub tom qab noj tshuaj. Feem ntau cov no yuav ploj mus li ob peb hnub. |
Cov kev mob tshwm sim uas tsis tshua muaj tab sis tsim nyog paub txog
Txawm hais tias cov no tsis tshua muaj , nws yog ib qho tseem ceeb kom paub txog lawv.
- Kev mob pob txha tawg ntawm lub puab tsaig: Qhov kev pheej hmoo no me heev, tshwj xeeb tshaj yog tom qab phais xws li rho hniav tawm. Yog li ntawd, yog tias koj noj cov tshuaj no, qhia rau koj tus kws kho hniav txhua zaus koj mus ntsib nws.
- Cov pob txha tawg uas tsis zoo li qub: Qhov no yog qhov tshwm sim tsawg tsawg ntawm cov neeg noj cov tshuaj no ntev heev (ntau tshaj 3-5 xyoos).
- Teeb meem qhov muag: Kev o (uveitis, scleritis) ntawm ntau qhov ntawm lub qhov muag tuaj yeem tshwm sim.
Qhov tseem ceeb tshaj plaws yog tias qhov kev pheej hmoo ntawm kev tawg pob txha vim yog osteoporosis yog tias koj tsis noj cov tshuaj no yog ib txhiab npaug ntau dua li qhov kev pheej hmoo me me ntawm cov kev mob tshwm sim no. Yog li ntawd, nws yog ib qho tseem ceeb heev uas yuav tsum ua raws li koj tus kws kho mob cov lus qhia.
Koj xav mus ntsib kws kho mob dua thaum twg?
Yog koj noj cov tshuaj no, nws yog ib qho tseem ceeb uas yuav tsum mus ntsib koj tus kws kho mob tsis tu ncua kom paub seb cov tshuaj puas ua haujlwm thiab puas muaj cov kev mob tshwm sim. Koj kuj tseem yuav raug xa mus rau tus kws kho mob pob txha (Endocrinologist lossis Rheumatologist).
Koj tus kws kho mob kuj tseem yuav pom zoo kom ua DXA scan kom pom tias koj cov pob txha tuab npaum li cas.
Lus Cim Tshwj Xeeb: Yog tias koj tau siv cov tshuaj no ntau tshaj peb xyoos thiab muaj mob tshiab hauv koj lub duav lossis qhov chaw mos, tsis txhob tsis quav ntsej thiab qhia rau koj tus kws kho mob tam sim ntawd.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Bisphosphonates yog ib yam tshuaj zoo heev uas pab txhawb kom cov pob txha uas qaug zog los ntawm osteoporosis muaj zog.
- Cov tshuaj no ua haujlwm los ntawm kev ua kom qeeb qeeb ntawm kev poob pob txha.
- Thaum noj tshuaj, nws yog ib qho tseem ceeb heev uas yuav tsum haus nws thaum lub plab khoob, nrog dej xwb, thiab sawv lossis zaum li 30-60 feeb tom qab noj tshuaj.
- Txawm hais tias tej zaum yuav muaj tej yam tsis zoo me me los xij, tej yam tsis zoo loj heev yeej tsis tshua muaj. Cov txiaj ntsig ntawm cov tshuaj no ntau dua li tej kev pheej hmoo.
- Yog koj muaj lus nug, kev txhawj xeeb, lossis kev tsis ntseeg txog cov tshuaj no, nrog koj tus kws kho mob tham txog nws yam tsis muaj lus qhia los ntawm kws kho mob. Tsis txhob tsum noj koj cov tshuaj yam tsis tau txais kev qhia los ntawm kws kho mob.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus