Koj puas tau hnov txog ib hom mob qog noj ntshav uas tsis tshua muaj thiab loj heev uas tshwm sim hauv lub raum, tshwj xeeb tshaj yog rau cov tub ntxhais hluas? Tej zaum tsis yog. Qhov no yog Renal Medullary Carcinoma, lossis luv luv RMC. Txawm hais tias nws tsis tshua muaj ntau, nws tseem ceeb heev uas yuav tsum paub txog nws, tshwj xeeb tshaj yog rau qee tus neeg. Txawm hais tias qhov no yog ib qho teeb meem loj me ntsis, tsis txhob ntshai. Cia peb tham txog nws hauv txoj kev yooj yim thiab nkag siab hnub no.
RMC yog dab tsi tiag?
Hais yooj yim xwb, Renal Medullary Carcinoma (RMC) yog ib hom mob qog noj ntshav hauv lub raum. Tab sis nws tsis tshua muaj, hnyav heev, thiab kis tau sai. Nws feem ntau tshwm sim rau cov tub ntxhais hluas, tshwj xeeb tshaj yog cov neeg uas muaj mob ntshav hu ua 'mob sickle cell' lossis 'sickle cell trait'.
Thaum peb tham txog mob qog noj ntshav hauv lub raum, hom mob uas feem ntau tshwm sim yog 'mob qog noj ntshav hauv lub raum'. RMC kuj yog ib hom mob qog noj ntshav hauv lub raum. Tab sis tsis muaj ib tus neeg mob qog noj ntshav hauv 100 tus neeg mob yuav muaj tus mob RMC no. Nws yog qhov tsis tshua muaj.
Dab tsi ua rau muaj tus mob cancer no?
Cov kws tshawb fawb thiab cov kws kho mob tseem tsis tau pom qhov ua rau qhov no yog 100% tseeb, tab sis muaj ib qho tseem ceeb uas tau txheeb xyuas lawm.
Peb lub raum muaj ib feem hu ua 'renal medulla'. Ib tug neeg uas muaj mob 'sickle cell' qee zaum muaj cov qe ntshav liab uas hloov mus ua ib daim duab sickle. Thaum qhov no tshwm sim, cov qe ntshav tuaj yeem lo ua ke thiab thaiv cov hlab ntsha hauv 'renal medulla' ntawm lub raum.
Qhov kev thaiv cov ntshav no ua rau cov cell hauv thaj chaw ntawd puas tsuaj. Tshwj xeeb, ib lub gene hu ua 'INI1' (tseem hu ua 'SMARCB1') hauv cov cell ntawd raug puas tsuaj. Lub gene 'INI1' no ua haujlwm ua 'tus saib xyuas' uas tiv thaiv cov cell kom tsis txhob ua mob qog noj ntshav. Thaum kuaj xyuas cov cell mob qog noj ntshav RMC, lub gene 'INI1' no tsis pom nyob hauv lawv. Yog li cov kws kho mob kuaj xyuas seb puas muaj lub gene 'INI1' no kom paub tseeb tias lub qog yog RMC lossis tsis yog.
Kuv puas muaj feem yuav mob RMC thiab?
Nws nyuaj rau hais tias leej twg yuav muaj tus kab mob no. Kev muaj ib tug neeg hauv koj tsev neeg uas muaj tus kab mob RMC tsis ua rau koj muaj feem yuav mob ntxiv. Qhov ntawd txhais tau tias nws tsis yog ib yam dab tsi uas khiav hauv tsev neeg.
Qhov ua rau muaj kev pheej hmoo tseem ceeb yog kab mob ntshav hu ua 'sickle hemoglobinopathy'. Uas yog, muaj 'kab mob sickle cell' lossis 'sickle cell trait'. Tab sis tsis tshua muaj neeg mob uas tsis muaj cov mob no kuj tuaj yeem mob RMC. Nws hu ua "renal cell carcinoma, unclassified with medullary phenotype" (RCCU-MP).
Yog koj saib cov ntaub ntawv txheeb cais:
- Ntau dua rau cov txiv neej dua li cov poj niam.
- Feem ntau nws cuam tshuam rau lub raum sab xis.
- Feem ntau kuaj pom tus kab mob no thaum muaj hnub nyoog hluas, ntawm 11 thiab 39 xyoo.
Nws yog ib qho tseem ceeb rau cov tub ntxhais hluas, tshwj xeeb tshaj yog cov neeg uas muaj tus kab mob sickle cell lossis tus cwj pwm sickle cell, kom paub txog cov tsos mob no, vim tias kev kuaj pom thaum ntxov yuav ua rau kev kho mob yooj yim dua. Yog tias muaj cov tsos mob, mus ntsib kws kho mob tam sim ntawd.
Cov tsos mob ntawm RMC yog dab tsi?
Muaj ntau yam tsos mob ntawm tus kab mob no. Yog tias koj muaj ib lossis ntau yam ntawm cov no, nws yog qhov zoo tshaj plaws mus nrhiav kev pab kho mob sai li sai tau.
| Cov tsos mob | Kev piav qhia |
|---|---|
| Mob hauv thaj tsam lub raum | Mob tas li ntawm ob sab ntawm lub plab thiab sab nraub qaum (saum lub puab tais). |
| Ntshav nyob rau hauv cov zis | Cov zis xim liab, liab, lossis xim av. Qee zaum yuav muaj ntshav uas lub qhov muag tsis pom. |
| Mob qog hauv plab | Ib lub pob los yog ib qho mob uas zoo li ib lub pob nyob rau ib sab ntawm lub plab. |
| Kev poob phaus tsis muaj laj thawj | Poob phaus sai sai hauv lub sijhawm luv luv, tsis tas siv zog dab tsi li. |
| Kub taub hau thiab hws hmo ntuj ntau zaus | Yog tias koj kub taub hau ntau zaus tsis muaj lwm yam laj thawj thiab hws ntau thaum hmo ntuj ua rau koj daim ntaub pua chaw pw ntub. |
Tus kws kho mob kuaj mob li cas?
Thaum koj qhia peb txog koj cov tsos mob, thawj qhov uas tus kws kho mob yuav ua yog kuaj koj. Tom qab ntawd koj tuaj yeem ua raws li cov kauj ruam no.
1.Kev kuaj mob ultrasound: Qhov no tuaj yeem muab lub tswv yim ntxhib txog seb puas muaj ib yam dab tsi zoo li qog hauv lub raum.
2. Kev thaij duab CT lossis MRI: Yog tias xav tias muaj qog nqaij hlav, yuav kom ua kev thaij duab CT lossis MRI kom pom tseeb txog qog nqaij hlav. Raws li cov duab no, tus kws kho mob tuaj yeem txiav txim siab seb nws yuav muaj feem mob qog nqaij hlav npaum li cas.
3. Kev kuaj mob qog nqaij hlav: Yog tias muaj kev xav tias muaj mob qog nqaij hlav, qhov kev kuaj no yuav ua los xyuas kom meej. Qhov no suav nrog kev ntxig ib rab koob me me rau hauv thaj chaw ntawm lub qog nqaij hlav, noj ib daim ntaub me me thiab kuaj nws hauv qab lub tshuab kuaj mob.
4. Kev kuaj noob caj noob ces: Cov qe ntshav uas tau los ntawm kev kuaj nqaij raug kuaj seb puas muaj cov noob caj noob ces 'INI1' uas tawm tsam mob qog noj ntshav uas peb tau tham txog ua ntej.
- Yog tias tus gene `INI1` ploj lawm , nws raug txheeb xyuas tias yog RMC.
- Yog tias tus gene `INI1` ploj lawm thiab tus neeg mob tsis muaj mob `sickle cell`, ces kuaj pom tias nws yog `RCCU-MP`.
- Yog tias muaj tus gene 'INI1' , nws tsis yog RMC, tab sis yog lwm hom qog nqaij hlav.
Cov kev kho mob rau qhov no yog dab tsi?
Vim tias RMC yog ib hom mob qog noj ntshav uas kis tau sai thiab hnyav heev, kev kho mob yuav tsum ua sai thiab hnyav ib yam nkaus.
- Kev kho mob qog noj ntshav: Qhov no yog thawj txoj kev kho mob uas siv ntau tshaj plaws. Nws yog kev muab cov tshuaj uas tua cov hlwb qog noj ntshav rau lub cev.
- Kev Phais Mob: Tshem tawm cov qog nqaij hlav thiab tej zaum lub raum uas raug mob.
- Kev Kho Mob Hluav Taws Xob: Kev rhuav tshem cov hlwb qog noj ntshav siv cov teeb hluav taws xob muaj zog.
Vim tias tus kab mob no tsis tshua muaj, kev tshawb fawb tseem tab tom ua mus. Cov kws tshawb fawb yeej ib txwm nrhiav kev kho mob tshiab thiab zoo dua rau RMC.
Puas muaj txoj hauv kev los tiv thaiv RMC?
Tu siab kawg li, tam sim no tsis muaj txoj hauv kev los tiv thaiv RMC kom tsis txhob loj hlob, thiab tsis muaj kev kuaj mob kom paub txog nws ua ntej cov tsos mob tshwm sim.
Qhov zoo tshaj plaws uas koj ua tau yog paub txog . Yog tias koj paub tias koj muaj tus kab mob sickle cell lossis tus cwj pwm sickle cell, nrhiav cov tsos mob uas tau hais los saum toj no. Yog tias koj muaj kev txhawj xeeb, mus ntsib koj tus kws kho mob tam sim ntawd.
Feem ntau, thaum kuaj pom tias muaj tus kab mob no, tus mob qog nqaij hlav twb kis mus rau cov qog ntshav hauv lub cev lossis lwm yam hauv lub cev xws li lub ntsws, lub siab, thiab pob txha lawm. Yog li ntawd, kev kuaj pom thaum ntxov yog txoj hauv kev zoo tshaj plaws los ua kom tau txais txiaj ntsig zoo tshaj plaws.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Mob qog nqaij hlav raum (RMC) yog ib hom mob qog nqaij hlav uas tsis tshua muaj tab sis loj heev uas feem ntau cuam tshuam rau cov tub ntxhais hluas.
- Qhov tseem ceeb tshaj plaws uas ua rau muaj qhov no yog muaj mob ntshav hu ua
sickle cell diseaselossissickle cell trait. - Mob nraub qaum/mob plab, muaj ntshav hauv cov zis, muaj pob hauv plab, thiab poob phaus yam tsis paub yog cov tsos mob tseem ceeb.
- Yog tias koj muaj tus kab mob sickle cell thiab muaj ib lossis ntau yam ntawm cov tsos mob saum toj no, mus ntsib koj tus kws kho mob tam sim ntawd yam tsis muaj kev ncua.
- Hauv tus kab mob no, kev kuaj mob thaum ntxov thiab pib kho mob yog lub sijhawm zoo tshaj plaws los cawm txoj sia.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus