Thaum peb kuaj peb cov roj cholesterol, feem ntau peb tsuas saib cov "cholesterol zoo" (HDL) thiab "cholesterol phem" (LDL), puas yog? Tab sis koj puas paub tias muaj ib hom roj cholesterol tseem ceeb heev uas ntau tus neeg tsis tham txog, tab sis zais rau hauv nruab nrab? Qhov no yog Lipoprotein (a), lossis luv luv Lp (a). Qhov tshwj xeeb txog qhov no yog tias nws yog txiav txim siab los ntawm peb cov noob caj noob ces, uas txhais tau tias nws tau dhau los ntawm ib tiam mus rau ib tiam, es tsis yog los ntawm yam peb noj thiab haus lossis kev tawm dag zog. Tej zaum koj yuav yog ib tus neeg noj qab nyob zoo heev, tab sis koj qib Lp (a) tej zaum yuav siab heev.
Lipoprotein(a) yog dab tsi tiag?
Hais yooj yim xwb, qhov no kuj yog ib qho me me uas muaj roj cholesterol hauv peb cov ntshav. Tab sis qhov teeb meem nrog qhov no yog tias nws qib feem ntau yog txiav txim siab los ntawm peb cov noob caj noob ces. Qhov no txhais tau tias yog tias koj niam, txiv, lossis ib tus neeg hauv koj tsev neeg muaj tus mob no, koj yuav muaj nws thiab. Nws tau hais tias kwv yees li ib ntawm tsib tus neeg hauv ntiaj teb muaj cov qib Lp (a) siab.
Qhov txaus ntshai ntawm qhov no yog tias muaj Lp (a) siab ntau ua rau muaj kev pheej hmoo ntawm kev mob plawv thiab mob hlwb thaum lawv tseem hluas. Feem ntau, tib neeg tsuas paub txog qhov no tom qab lawv muaj mob plawv lossis mob hlwb. Qhov no yog vim tias daim ntawv lipid panel tsis qhia tus nqi Lp (a) no. Nws yuav tsum tau kuaj cais.
Piv txwv li, xav txog zaj dab neeg ntawm Bernadette, ib tug poj niam muaj hnub nyoog 66 xyoo uas taug kev li 10 mais ib hnub thiab noj zaub mov uas muaj cov nroj tsuag, suav nrog zaub thiab taum pauv. Nws cov roj cholesterol feem ntau nyob rau hauv qhov zoo, tab sis nws qib Lp (a) siab dua tsib npaug ntawm qib kev pheej hmoo. Qhov no yog vim nws cov noob caj noob ces. Nws niam thiab pog ob leeg tau tuag vim muaj kab mob plawv.
"Qhov teeb meem loj tshaj plaws rau kuv yog kev ntxhov siab ntawm kev nyob nrog qhov no. Txawm hais tias kuv xav tias mob me ntsis, kuv xav tias, 'Qhov no puas yog qhov mob plawv uas kuv yuav muaj?'" Bernadette hais.
Qhov teeb meem thiab kev cia siab tshiab
Txog rau tam sim no, tsis tau muaj tshuaj tshwj xeeb uas tau pom zoo kom txo qis Lp (a) theem. Qhov no txhais tau tias txawm tias lawv paub tias nws muaj tseeb los xij, ntau tus neeg tau nyob hauv kev ntshai, tsis muaj dab tsi uas lawv ua tau txog nws. Nws zoo li muaj lub foob pob sijhawm hauv lawv lub cev uas tuaj yeem tawg txhua lub sijhawm.
Tiam sis, tam sim no qhov xwm txheej ntawd yuav hloov pauv!
Cov kws tshawb fawb kho mob tam sim no tab tom tshawb nrhiav tsib yam tshuaj tshiab uas tau pom tias txo qis Lp (a) theem. Qhov no yog kev cia siab zoo rau ntau lab tus tib neeg uas muaj Lp (a) theem siab. Raws li tus thawj coj tshawb fawb Dr. Steven Nissen hais tias, " Tsis txhob txhawj, cov kev daws teeb meem yuav los. "
Cov tshuaj tshiab kawg uas nyob rau theem kev tshawb fawb
Cov tshuaj tshiab no tseem nyob rau theem kawg ntawm kev tshawb fawb (kev sim tshuaj). Yog tias lawv ua tiav, lawv yuav muaj nyob rau hauv kev ua lag luam yav tom ntej. Cia peb saib cov tshuaj ntawd yog dab tsi thiab lawv ua tiav npaum li cas.
| Lub Npe Tshuaj | Nta / Yuav ua li cas muab | Qhov tshwm sim xav tau |
|---|---|---|
| Pelacarsen | Ib qho kev txhaj tshuaj ib hlis ib zaug | Cov theem Lp (a) tuaj yeem txo qis li ntawm 80%. |
| Olpasiran | Ib qho tshuaj tiv thaiv kab mob uas tau txhaj txhua 3 lub hlis | Cov theem Lp (a) tuaj yeem txo tau ntau dua 95%. |
| Lepodisiran | Ib koob tshuaj tiv thaiv kab mob uas tseem ua haujlwm tau yuav luag ib xyoos | Cov theem Lp (a) tuaj yeem txo qis li ntawm 94% thiab tswj tau ntev. |
| Zerlasiran | Ib qho tshuaj tiv thaiv kab mob uas tsis tshua muaj | Cov theem Lp (a) tuaj yeem txo tau li ntawm 86%. |
| Muvalaplin | Ib lub tshuaj ntsiav txhua hnub | Cov theem Lp (a) tuaj yeem txo tau li ntawm 86%. |
Dab tsi yog qhov tshwj xeeb txog cov tshuaj ntsiav Muvalaplin?
Ntawm cov no, cov kws tshawb fawb muaj kev cia siab rau cov tshuaj hu ua "(Muvalaplin)" vim tias thaum plaub yam tshuaj ntxiv yuav tsum tau muab ua tshuaj txhaj, qhov no tuaj yeem noj ua tshuaj txhua hnub . Yog li ntawd, nws yuav yooj yim dua rau cov neeg mob, thiab nws kuj tseem yuav pheej yig dua.
Lwm cov tshuaj ua haujlwm los ntawm kev ua kom lub noob caj noob ces uas ua rau Lp (a) tsim tawm ntsiag to. Tab sis cov tshuaj no ua haujlwm txawv. Nws nres qhov tsim cov khoom me me Lp (a) hauv nruab nrab. Qhov no tso cai rau nws ua haujlwm yam tsis cuam tshuam rau lub siab thiab raug tshem tawm ntawm lub cev sai sai yog tias muaj kev phiv tshwm sim.
Vim li cas peb thiaj yuav tsum sim Lp (a)?
Thaum koj nyeem tsab xov xwm no, tej zaum koj yuav xav tias, 'Kuv puas yuav tsum tau kuaj qhov no thiab?' Cov lus teb yog, yog! Koj yuav tsum xav txog qhov no, tshwj xeeb tshaj yog tias ib tug neeg hauv koj tsev neeg tau muaj kab mob plawv lossis mob hlwb thaum nws tseem hluas .
Lub Koom Haum Lipid Hauv Tebchaws tam sim no pom zoo kom txhua tus neeg mus kuaj lawv cov roj Lp(a) tsawg kawg ib zaug hauv lawv lub neej . Vim tias nws yog ib yam uas los ntawm noob caj noob ces, qib ntawd tsis hloov pauv ntau thoob plaws hauv lub neej. Tsuas yog kuaj ib zaug xwb twb txaus lawm.
Qhov no yog kev kuaj ntshav yooj yim heev. Txawm li cas los xij, vim tias nws tsis suav nrog hauv daim ntawv qhia txog cov roj cholesterol, koj yuav tsum nug koj tus kws kho mob txog qhov no ua ntej ua qhov kev kuaj no.
Paub koj qib Lp(a) yog thawj kauj ruam. Yog tias nws siab, tsis txhob ntshai. Nrog cov tshuaj tshiab no yuav los sai sai no, koj yuav muaj peev xwm tswj koj qhov kev pheej hmoo ntawm kev mob plawv thiab mob hlwb. Txog thaum ntawd, nws yog ib qho tseem ceeb kom tswj hwm lwm yam kev pheej hmoo, xws li ntshav siab, ntshav qab zib, haus luam yeeb, thiab cov roj cholesterol LDL, kom zoo.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Lipoprotein(a), los yog Lp(a), yog ib hom roj cholesterol uas raug tswj los ntawm noob caj noob ces thiab ua rau muaj kev pheej hmoo ntawm kab mob plawv.
- Qhov no tsis suav nrog rau hauv kev kuaj roj cholesterol (lipid profile), yog li koj yuav tsum nug koj tus kws kho mob txog qhov no thiab kuaj xyuas nws tshwj xeeb.
- Yog tias muaj leej twg hauv koj tsev neeg tau muaj kab mob plawv thaum tseem hluas, nws yog ib qho tseem ceeb heev uas yuav tsum tau ua qhov kev kuaj no.
- Txawm hais tias tam sim no tsis muaj tshuaj tshwj xeeb rau Lp(a), ntau yam tshuaj uas pom tau tias muaj txiaj ntsig zoo heev tab tom nyob rau theem kawg ntawm kev tshawb fawb. Qhov no muaj txiaj ntsig zoo heev.
- Yog koj pom tias koj qib Lp(a) siab, tsis txhob ntshai, nrog koj tus kws kho mob tham, thiab tswj hwm lwm yam kev pheej hmoo ntawm kab mob plawv.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus