Koj puas feem ntau muaj mob gastritis? Los yog koj puas muaj qhov kub hnyiab hauv koj lub hauv siab lossis muaj qhov mob hauv koj lub caj pas? Thaum lub sijhawm zoo li no, ntau tus ntawm peb tau siv los noj tshuaj los ntawm lub tsev muag tshuaj. Feem ntau, hom tshuaj noj li no yog Proton Pump Inhibitors, lossis raws li peb hu nws, "tshuaj gastritis". Tab sis, peb puas paub meej tias cov tshuaj no yog dab tsi, lawv ua haujlwm li cas, thiab lawv yuav tsum noj ntev npaum li cas? Hnub no, peb yuav tham txog qhov no.
Cov tshuaj proton pump inhibitors (PPIs) no yog dab tsi?
Hais yooj yim xwb, qhov no yog ib hom tshuaj uas txo qhov acidity, lossis acid, hauv koj lub plab. Tam sim no koj yuav xav tias, "Puas yog nws tsis zoo kom muaj kua qaub hauv plab?" Kua qaub hauv plab yog ib yam dab tsi uas peb tsis tuaj yeem nyob yam tsis muaj. Nws pab peb zom cov zaub mov uas peb noj thiab tua cov kab mob phem uas nkag mus rau hauv cov zaub mov.
Tiamsis qhov teeb meem pib thaum cov kua qaub no ntau dhau, lossis thaum nws mus rau qhov chaw uas nws tsis tsim nyog, zoo li koj lub caj pas. Thaum ntawd cov teeb meem xws li mob siab thiab mob plab pib. Thaum ntawd cov tshuaj no hu ua PPIs tuaj pab peb.
Cov mob tseem ceeb uas kho nrog PPIs yog dab tsi?
Cov tshuaj PPIs siv los kho ntau yam mob uas cuam tshuam nrog cov kua qaub hauv plab. Cia peb saib cov tseem ceeb.
| Mob nkeeg | Hauv lus yooj yim, qhov tshwm sim yog |
|---|---|
| GERD / Chronic Acid Reflux | Qhov no yog qhov peb feem ntau hu ua mob plab. Cov kua qaub hauv plab txav mus rau hauv txoj hlab pas tuaj yeem ua rau puas tsuaj rau txoj hlab pas (erosive esophagitis) . PPIs txo cov kua qaub hauv plab thiab cia qhov kev puas tsuaj kho. |
| Mob plab hnyuv (Peptic Ulcers) | Cov kua qaub hauv plab tuaj yeem ua rau lub txheej tiv thaiv ntawm lub plab lossis txoj hnyuv me puas tsuaj, ua rau muaj mob qog. Cov mob qog no kuj tseem tuaj yeem tshwm sim yog tias siv cov tshuaj tua kab mob (NSAIDs) tas li. Cov tshuaj PPI tuaj yeem pab kho cov mob qog no. |
| Kev kis tus kab mob H. pylori | Qhov no yog ib hom kab mob uas ua rau mob plab. Cov tshuaj PPIs raug muab nrog rau cov tshuaj tua kab mob kom tua cov kab mob no. Qhov no txo cov kua qaub hauv plab, ua rau cov tshuaj tua kab mob ua haujlwm zoo dua. |
| Zollinger-Ellison syndrome | Qhov no yog ib qho mob tsis tshua muaj. Qee cov qog nqaij hlav hauv lub cev tsim cov tshuaj hormones uas ua rau lub plab tsim cov kua qaub ntau dhau. PPIs tuaj yeem tswj tau qhov mob no. |
Cov tshuaj no ua haujlwm li cas?
Qhov no yooj yim to taub heev. Xav txog tias muaj cov 'twj' me me hauv koj lub plab uas ua kua qaub. Raws li kev tshawb fawb, cov no hu ua cov twj hydrogen-potassium ATPase. Hauv luv luv, lawv yog "cov twj proton."
Tam sim no, qhov uas cov tshuaj PPI no ua yog 'txwv' cov twj tso kua qaub ntawd kom tsis txhob ua haujlwm, uas yog, nws txwv lawv. Nws zoo li tua lub qhov hloov ntawm lub tshuab dej.
Tiamsis qhov no tsis tau txwv tsis pub cov kua qaub hauv plab tsim tawm. Yog tias koj noj PPI li 5 hnub sib law liag, cov kua qaub hauv plab yuav raug txo kom tsawg li 65%. 35% seem yog txaus los zom zaub mov. Yog li ntawd, tsis muaj dab tsi yuav tsum txhawj txog.
Cov hom tshuaj PPIs twg feem ntau siv?
Muaj ntau hom tshuaj PPI. Qee hom tuaj yeem yuav tau yam tsis tas yuav muaj daim ntawv yuav tshuaj (OTC) ntawm lub tsev muag tshuaj yam tsis tas yuav muaj daim ntawv yuav tshuaj los ntawm kws kho mob, thaum lwm hom yuav tsum muaj daim ntawv yuav tshuaj los ntawm kws kho mob.
| Lub Npe Dav Dav | Cov Npe Hom Lag Luam Feem Ntau |
|---|---|
| Cov hom tshuaj muaj nrog lossis tsis muaj daim ntawv qhia los ntawm kws kho mob | |
| Esomeprazole | Nexium® |
| Lansoprazole | Prevacid® |
| Omeprazole | Prilosec® |
| Cov hom muaj tsuas yog nyob rau ntawm daim ntawv sau tshuaj xwb | |
| Dexlansoprazole | Dexilant® |
| Pantoprazole | Protonix® |
| Rabeprazole | AcipHex® |
Yuav tsum siv cov no li cas?
Cov tshuaj no muaj nyob rau hauv daim ntawv tshuaj ntsiav lossis ntsiav tshuaj. Rau cov neeg uas muaj teeb meem nqos tshuaj, qee cov tshuaj ntsiav tuaj yeem sib tov nrog ib yam dab tsi zoo li kua txiv applesauce kom tau txais cov hmoov.
Qhov tseem ceeb tshaj plaws yog thaum twg yuav tsum noj tshuaj. Feem ntau cov tshuaj PPIs zoo tshaj plaws thaum noj thaum lub plab khoob . Feem ntau pom zoo kom noj li 30 feeb txog ib teev ua ntej noj tshais. Qhov laj thawj yog vim qhov no muab sijhawm rau cov tshuaj kom nqus tau thiab pib ua haujlwm, ua ntej cov kua qaub hauv plab nce ntxiv tom qab koj noj mov.
Kuv yuav tsum yuav ntau npaum li cas?
Qhov no yeej yog ib yam uas koj tus kws kho mob yuav txiav txim siab. Tej zaum yuav muaj ib txhia neeg xav tau ib lub tshuaj thaum sawv ntxov. Tej zaum lwm tus yuav raug qhia kom noj ib lub thaum sawv ntxov thiab ib lub thaum hmo ntuj. Nws nyob ntawm koj tus mob. Yog li ntawd, nws yog ib qho tseem ceeb heev uas yuav tsum ua raws li koj tus kws kho mob cov lus qhia.
Nws siv sijhawm ntev npaum li cas rau PPIs ua haujlwm?
Cov tshuaj no tsis yog tshuaj uas yuav pab tau sai sai. Tej zaum yuav siv sijhawm 1 txog 4 hnub kom koj thiaj li hnov cov txiaj ntsig tag nrho ntawm cov tshuaj.
Xav txog koj noj zaub mov ntsim thiab mam li hnov mob kub hnyiab hauv koj lub hauv siab. Thaum lub sijhawm zoo li no, cov tshuaj antacid (piv txwv li, Digene) lossis cov tshuaj histamine (H2) blocker (piv txwv li, Famotidine) yuav pab tau sai dua li PPI. Txawm li cas los xij, lawv cov teebmeem ploj mus sai.
Cov tshuaj PPIs yog ib txoj kev kho mob uas muab cov txiaj ntsig mus sij hawm ntev, zoo tshaj plaws rau cov neeg uas muaj teeb meem kua qaub ncaug ntev.
Puas muaj tej yam tshwm sim tsis zoo rau cov no?
Cov neeg feem coob tsis muaj kev phiv tshuaj, tab sis zoo li lwm yam tshuaj, qee tus neeg yuav muaj kev phiv me me.
- Mob plab
- Kab mob cem quav
- Mob raws plab
- kiv taub hau
- Qhov ncauj qhuav
- Mob taub hau
- Ua npaws
- Ua kom lub plab puv
- Khaus thiab mob plab
Kev pheej hmoo ntawm kev siv mus sij hawm ntev
Txawm hais tias PPIs feem ntau suav hais tias yog cov tshuaj muaj kev nyab xeeb, cov kws tshawb fawb tau txheeb xyuas qee qhov kev pheej hmoo cuam tshuam nrog kev siv lawv rau lub sijhawm ntev yam tsis muaj lus qhia kho mob .
- Kev kis tus kab mob Clostridium difficile (C. diff): Qhov sib npaug ntawm cov kab mob zoo thiab cov kab mob phem hauv plab hnyuv hloov pauv, ua rau raws plab txaus ntshai.
- Pob Txha: Nws tuaj yeem ua rau lub cev nyuaj dua los nqus cov calcium, uas tuaj yeem ua rau muaj kev pheej hmoo ntawm pob txha tawg hauv lub duav, dab teg, lossis tus txha nraub qaum.
- Kab mob raum: Kev siv ntev mus ntev yuav ua rau muaj kev pheej hmoo ntawm kev mob raum ntev (CKD).
- Kev Tsis Txaus Noj Haus: Lub cev tuaj yeem txo nws qhov kev nqus ntawm magnesium thiab vitamin B12. Cov no yog cov as-ham tseem ceeb rau peb lub paj hlwb thiab cov leeg nqaij.
Cov kev pheej hmoo no tseem tab tom kawm, yog li cov kws kho mob feem ntau sim tswj koj cov tsos mob los ntawm kev muab cov tshuaj tsawg tshaj plaws rau koj rau lub sijhawm luv tshaj plaws .
Kuv yuav tsum mus ntsib kws kho mob thaum twg?
Yog tias koj tau txais kev pab los ntawm kws kho mob, koj yuav tsum nrog koj tus kws kho mob tham txog kev tsum tsis txhob noj tshuaj lossis hloov qhov ntau npaum li cas.
Yog tias koj siv cov tshuaj PPI uas yuav tsis tas yuav muaj ntawv yuav tshuaj (OTC) thiab pom tias koj xav tau lawv txhua hnub los tswj koj cov tsos mob, koj yuav tsum mus ntsib kws kho mob kom koj thiaj li tau txais kev kuaj mob thiab kev kho mob zoo.
Yog tias koj muaj cov tsos mob hauv qab no, mus ntsib koj tus kws kho mob tam sim ntawd:
| Cov tsos mob | Kev piav qhia |
|---|---|
| Kev ua xua | Kev khaus ntawm daim tawv nqaij, khaus heev, o. |
| Cov cim qhia txog kev puas tsuaj rau lub raum | Cov zis tso tawm tsawg dua, o ntawm tes, pob luj taws, lossis taw. |
| Cov cim qhia ntawm kev tsis txaus magnesium | Qaug zog heev, lub plawv dhia tsis xwm yeem, mob nqaij. |
| Cov cim qhia ntawm qhov tsis txaus vitamin B12 | Mob, loog, kiv taub hau , tsis meej pem hauv caj npab lossis ceg. |
| Raws plab hnyav los yog kub taub hau | Mob raws plab lossis kub taub hau tas li. |
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Cov tshuaj PPIs yog kev kho mob rau cov teeb meem kua qaub ncaug ntev, tsis yog rau kev pab tam sim ntawd.
- Noj koj cov tshuaj raws li lub sijhawm tau teem tseg (feem ntau yog ua ntej noj mov), raws li koj tus kws kho mob hais.
- Tsis txhob siv cov tshuaj PPIs tas mus li rau lub sijhawm ntev yam tsis tau kev qhia los ntawm kws kho mob.
- Yog tias koj xav tau cov tshuaj no txhua hnub lossis yog tias muaj cov kev mob tshwm sim, nco ntsoov mus ntsib koj tus kws kho mob.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus