Kev ua neej nyob nrog mob qog noj ntshav yog ib qho kev tawm tsam tiag tiag. Txawm hais tias kev kho mob xws li chemotherapy tuaj yeem pab rhuav tshem cov hlwb qog noj ntshav, qee zaum cov kev kho mob ntawd tuaj yeem ua rau muaj teeb meem tsis tau xav txog. Hnub no, peb yuav tham txog qhov xwm txheej ceev uas xav tau kev saib xyuas tam sim ntawd thiab tuaj yeem ua rau tuag taus . Qhov no hu ua Tumor Lysis Syndrome.
Kab mob Tumor Lysis Syndrome yog dab tsi? Cia peb nkag siab yooj yim.
Hais yooj yim xwb, Tumor Lysis Syndrome yog ib pawg mob hnyav uas tshwm sim thaum muaj ntau lub hlwb mob qog noj ntshav tuag ib zaug thiab cov ntsiab lus ntawm cov hlwb ntawd raug tso tawm rau hauv cov ntshav. Xav txog, qhov mob no tuaj yeem tshwm sim hauv ob peb teev tom qab pib kho mob qog noj ntshav. Nws tuaj yeem loj hlob sai heev thiab dhau los ua qhov mob uas xav tau kev kho mob thaum muaj xwm txheej ceev. Yog li ntawd, cov kws kho mob yeej ib txwm saib xyuas qhov no.
Tiam sis muaj xov xwm zoo. Cov kws kho mob muaj txoj hauv kev los tiv thaiv Tumor Lysis Syndrome kom tsis txhob tshwm sim . Lawv ua qhov no los ntawm kev txheeb xyuas leej twg muaj kev pheej hmoo siab dua thiab ua cov kauj ruam los txo qhov kev pheej hmoo ntawd.
Ua li cas rau peb lub cev hauv qhov xwm txheej no?
Thaum cov hlwb qog nqaij hlav raug kev ntxhov siab, tshwj xeeb tshaj yog los ntawm kev kho mob xws li chemotherapy, lawv tawg. Tom qab ntawd, cov tshuaj lom neeg thiab cov tshuaj lom hauv cov hlwb ntawd cia li sib sau ua ke ntau heev hauv cov ntshav. Qhov teeb meem pib thaum peb lub cev tsis tuaj yeem tshem tawm cov no sai sai. Qhov mob qog nqaij hlav lysis no feem ntau tuaj yeem cuam tshuam rau peb lub plawv, raum, thiab cov leeg. Cia peb saib cov teebmeem no yog dab tsi:
- Hyperuricemia - Qhov no txhais tau tias muaj cov uric acid ntau ntxiv: Thaum cov uric acid hauv cov ntshav ntau ntxiv, nws tuaj yeem tso rau hauv lub raum, ua rau lub raum tsis ua haujlwm thiab txawm tias lub raum tsis ua haujlwm. Xav txog nws zoo li qhov txhaws hauv cov yeeb nkab dej.
- Hyperphosphatemia - uas yog, cov phosphorus ntau ntxiv: Cov phosphorus ntau ntxiv hauv cov ntshav kuj cuam tshuam rau kev ua haujlwm ntawm lub raum.
- Hyperkalemia - Qhov no txhais tau tias muaj cov potassium ntau: Thaum cov potassium ntau, koj yuav muaj cov tsos mob xws li xeev siab, ntuav, thiab raws plab. Tsis yog li ntawd xwb, tab sis koj lub plawv dhia kuj yuav hloov pauv, ua rau lub plawv dhia tsis xwm yeem, thiab tej zaum yuav mob plawv nres. Qhov no txaus ntshai me ntsis, puas yog?
- Uremia: Qhov no tshwm sim thaum lub raum tsis lim cov tshuaj lom tawm ntawm cov ntshav. Uremia tuaj yeem ua rau muaj teeb meem loj nrog cov pob txha, cov leeg, lub plawv, thiab cov hlab ntsha.
- Hypocalcemia - Cov calcium qis: Cov calcium qis hauv cov ntshav tuaj yeem ua rau lub plawv dhia hloov pauv, mob nqaij, tsis meej pem, loog thiab tingling hauv ob txhais ceg. Qee zaum, txawm tias tuag los ntawm kev plawv nres kuj tuaj yeem tshwm sim.
Qhov tseem ceeb tshaj plaws: Tumor Lysis Syndrome tshwm sim thaum ib lossis ntau yam ntawm cov mob no los ua ke.
Puas yog Tumor Lysis Syndrome yog qhov xwm txheej ceev?
Yog, muaj tseeb tiag! Kab mob Tumor Lysis Syndrome yog ib qho xwm txheej ceev uas yuav tsum tau kho tam sim ntawd. Yog li ntawd, nws yog ib qho tseem ceeb heev uas yuav tsum paub txog qhov no.
Leej twg thiaj li raug tus mob no?
Tsis yog txhua tus neeg uas tau txais kev kho mob qog noj ntshav yuav muaj tus mob Tumor Lysis Syndrome. Yog tias koj tab tom txais kev kho mob qog noj ntshav, nws yog ib lub tswv yim zoo los nug koj tus kws kho mob txog qhov no. Feem ntau, cov neeg uas tau txais chemotherapy rau cov hom qog noj ntshav hauv qab no muaj feem yuav mob no ntau dua:
- Kab mob qog ntshav Lymphocytic loj heev
- Cov kab mob Lymphoma Non-Hodgkin uas ua rau mob hnyav, xws li Burkitt Lymphoma thiab Diffuse Large B-cell Lymphoma
- Kab mob ntshav dawb Acute Myeloid Leukemia (AML)
- Kab mob qog ntshav B-cell Acute Lymphoblastic Leukemia (ALL)
- Mob Cancer Ntawm Lub Ntsws Me Me
Tsis tas li ntawd xwb, muaj qee hom mob qog noj ntshav uas, thaum kho mob lawm, muaj feem yuav mob no tsawg dua me ntsis. Tab sis nws tsis ploj mus tag. Piv txwv li:
- Anaplastic Large Cell Lymphoma - Qhov no yog ib hom mob qog noj ntshav uas tsis tshua muaj, loj hlob qeeb ntawm lub cev tiv thaiv kab mob.
- Kab mob qog ntshav Lymphocytic ntev (CLL)
- Neuroblastoma
- Mob Cancer Mis
- Mob Sarcoma ntawm Cov Nqaij Mos
- Medulloblastoma
- Merkel Cell Carcinoma
Lwm yam ua rau muaj Tumor Lysis Syndrome yog dab tsi?
Cov kws kho mob paub tias qee tus neeg muaj feem yuav mob no ntau dua. Yuav tsum ceev faj ua ntej muab tshuaj chemotherapy rau cov neeg zoo li no. Nov yog qee yam uas ua rau muaj kev pheej hmoo ntau ntxiv:
- Muaj cov qe ntshav dawb ntau heev.
- Cov theem uric acid hauv cov ntshav twb siab lawm.
- Muaj teeb meem raum.
- Kev txo qis ntawm cov dej hauv lub cev (Kev qhuav dej).
- Muaj mob qog noj ntshav nyob rau theem hnyav (mob qog noj ntshav theem tom qab).
- Muaj cov qog loj.
Tus mob no puas tshwm sim tau yam tsis muaj tshuaj kho mob?
Yog, tab sis nws tshwm sim tsawg heev . Thaum nws tshwm sim, cov kws kho mob hu nws ua Spontaneous Tumor Lysis Syndrome.
Cov tsos mob ntawm Tumor Lysis Syndrome yog dab tsi?
Cov tsos mob no feem ntau tshwm sim li ntawm 12 txog 72 teev tom qab pib siv tshuaj chemotherapy. Nov yog lawv yog dab tsi:
- Xeev siab thiab ntuav.
- Mob raws plab.
- Kev hloov pauv ntawm cov zis uas koj tso tawm (tej zaum yuav nce lossis txo).
- Tsis muaj zog thiab Lethargy.
- Ntshav nyob rau hauv cov zis (Hematuria).
- Cov mob qaug dab peg, uas yog, qaug dab peg.
- Mob Nqaij Mob.
- Ua tsis taus pa.
- Lub plawv dhia tsis xwm yeem.
- Ntshav siab qis (Hypotension).
- Mob Pob Qij Txha.
Yog tias koj muaj ib lossis ntau yam ntawm cov tsos mob no thaum koj tab tom kho mob qog noj ntshav, koj yuav tsum qhia rau kws kho mob tam sim ntawd.
Vim li cas thiaj muaj Tumor Lysis Syndrome?
Hais yooj yim xwb, qhov mob no tshwm sim thaum kev kho mob qog noj ntshav ua rau muaj ntau cov qe ntshav qog noj ntshav tuag sai sai thiab sai. Cov tshuaj hauv cov qe ntshav uas tab tom tuag (xws li potassium, phosphorus, thiab uric acid) cia li sib sau ua ke hauv cov ntshav.
Feem ntau, peb lub raum yog cov uas lim cov khoom tsis xav tau no. Tab sis, thaum muaj ntau lub cell tuag tag nrho ib zaug, lub raum ua tsis tau txoj haujlwm no. Nws zoo li lub qhov dej txhaws thaum muaj ntau yam khib nyiab nkag los ib zaug. Tom qab ntawd cov tshuaj lom no pib sib sau ua ke hauv lub cev.
Cov kws kho mob kuaj mob li cas?
Cov kws kho mob lub hom phiaj tseem ceeb yog tiv thaiv kab mob Tumor Lysis Syndrome. Yuav ua li no, lawv yuav kuaj ntshav thiab zis tas li kom paub tseeb tias koj lub raum ua haujlwm zoo thiab cov tshuaj lom raug tshem tawm ntawm koj lub cev.
Cov kev kho mob rau Tumor Lysis Syndrome yog dab tsi?
Cov kws kho mob thawj zaug sim ua kom tsis txhob muaj qhov no. Lawv ua qhov no los ntawm kev txheeb xyuas cov neeg uas muaj feem yuav mob ntau dua thiab ua tib zoo saib xyuas lawv. Tab sis, yog tias muaj qhov mob no, kev kho mob yuav pib tam sim ntawd.
Tej yam yuav tsum ua kom tiv thaiv tau:
- Kev Haus Dej Hauv Kab Mob (IV): Qhov no pab tswj kom muaj dej txaus, txhawb kev tso zis, thiab pab tshem tawm cov tshuaj lom tawm ntawm lub cev sai sai.
- Muab cov tshuaj uas tiv thaiv kom cov uric acid crystals tsis txhob sib sau ua ke hauv lub raum: Muaj qee cov tshuaj uas pab tswj cov uric acid.
Kev kho mob yog tias qhov mob tshwm sim:
- Muab cov tshuaj diuretics: Qhov no pab tshem tawm cov tshuaj lom tawm ntawm lub cev sai dua.
- GLISH: Muab cov tshuaj uas tshem tawm cov potassium thiab phosphorus ntau dhau.
- Muab cov tshuaj uas yaj cov uric acid crystals uas tau tsim nyob rau hauv lub raum.
- Kev ntxuav ntshav: Yog tias koj lub raum tsis ua haujlwm zoo, koj yuav tsum tau ntxuav ntshav kom tshem tawm cov tshuaj lom ntawm koj cov ntshav. Qhov no zoo li ua haujlwm ntawm koj lub raum yam tsis siv neeg.
Puas kho tau Tumor Lysis Syndrome?
Yog, yeej muaj tseeb tiag! Yuav luag 90 feem pua ntawm cov neeg uas muaj tus mob no rov zoo. Qhov tseem ceeb tshaj plaws yog kuaj mob thaum ntxov thiab pib kho thaum ntxov.
Tom qab kho tus mob no tas lawm, yuav muaj dab tsi tshwm sim?
Kab mob Tumor Lysis Syndrome tuaj yeem ua rau koj lub raum puas tsuaj. Yog li ntawd, yog tias koj muaj tus mob no, nws yog ib qho tseem ceeb heev uas yuav tsum nug koj tus kws kho mob yog tias koj xav tau kev kho mob ntxiv lossis kev saib xyuas tshwj xeeb kom txog thaum koj lub raum zoo.
Kev kho mob qog noj ntshav zoo zuj zus txhua hnub, ua rau peb muaj peev xwm rhuav tshem cov hlwb qog noj ntshav sai sai. Txawm li cas los xij, qee zaum, thaum cov hlwb no tuag, cov tshuaj lom thiab cov tshuaj lom uas lawv tso tawm tuaj yeem ua rau muaj mob txaus ntshai hu ua Tumor Lysis Syndrome. Qhov no tuaj yeem muaj kev cuam tshuam loj rau lub plawv thiab lub raum.
Thaum kawg, yuav tsum nco ntsoov li cas (Cov Lus Coj Mus Tsev)
Kev kho mob qog noj ntshav yog ib qho kev cov nyom. Lub sijhawm no, nws yog ib qho tseem ceeb uas yuav tsum paub txog tej xwm txheej ceev xws li Tumor Lysis Syndrome. Yog tias koj tab tom kho mob qog noj ntshav, nco ntsoov nug koj tus kws kho mob yog tias koj muaj feem yuav mob no. Lawv yuav piav qhia txog tej kev pheej hmoo rau koj thiab ua txhua yam uas lawv ua tau los tiv thaiv lossis kho tus mob no yog tias nws tshwm sim. Tsis txhob tsis quav ntsej txog tej tsos mob, thiab qhia rau kws kho mob tam sim ntawd yog tias koj pom muaj dab tsi txawv txawv. Kev saib xyuas koj txoj kev noj qab haus huv yog qhov tseem ceeb tshaj plaws!
Kev mob qog nqaij hlav lysis syndrome, kev kho mob qog noj ntshav, kev siv tshuaj chemotherapy, kab mob raum, hyperkalemia, hyperuricemia, kev kho mob thaum muaj xwm txheej ceev
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus