Yu dɔn ɛva notis se yu mɔt kin dray ɔltɛm, yu yay kin blɔk smɔl, ɔ yu bɛlɛ kin dray ɔltɛm bikɔs ɔf sɔm mɛrɛsin dɛn we yu kin tek? Yu kin tink se dis na ɔda tin we yu sik kin mek. Bɔt di rizin fɔ dis kin bi bikɔs yu nɔ no se yu de tek mɛrɛsin we gɛt anticholinergic prɔpati. Nɔ wɔri, dis kin rili kɔmɔn. Tide, wi go tɔk bɔt dis simpul we we yu go ɔndastand.
Wetin na dɛn anticholinergic mɛrɛsin ya rili?
Dis nem kin tan lɛk se i kɔmplikt smɔl. Bɔt di stori rili simpul. Wi bɔdi in nervɔs sistɛm na wan rili wɔndaful nɛtwɔk. Dis na wetin de kɔntrol ɔltin frɔm di we aw wi de tink, di we aw wi de muv, aw wi de blo, ɛn aw wi at de bit. "mεsenja" dεm de insay dis nεv sεstem fכ kכri mεsej dεm bak εn go bifo. Jɔs lɛk aw pipul dɛn de sɛn lɛta dɛn na post ɔfis. Wi kin kɔl dɛn mɛsenja ya `(Nyurotransmitta)`.
Wan pan dɛn kayn mɛsenja dɛn de we rili impɔtant na asɛtilkolin .
Naw lɛ wi si wetin na di men wok we dis `Acetylcholine` de du. tu men pat dεm de na wi כtonom nεv sεstem.
1. Simpatik sistεm: Dis na wi "fight-or-flight" sistεm. Fɔ tɔk am simpul wan, dis sistɛm de rɛdi wi fɔ gɛt ɛni imejensi, fɔ fred, ɔ fɔ trɛtin. I tan lɛk di aksilarayt we de insay motoka. We i de wok, wi at kin bit fast fast, wi yay kin opin, ɛn wi kin swet.
2. Parasympathetic system: Dis na wi "rεst-εn-daygεst" sistεm. Dis min se dis sistɛm de ɛp di bɔdi fɔ mek i kol, fɔ digest it, ɛn fɔ rilaks. I tan lɛk di brek we de na motoka. Wi mɛsenja we dɛn kɔl `Acetylcholine` de wok mɔ na dis sistɛm.
Okay, naw yu ɔndastand di bakgrɔn fɔ di stori, nɔto so? di anticholinergic dכg dεm de wok bay we dεn de intafεr di wok we da mεsenja de we dεn kכl `Acetylcholine` de du. Dat min se we da mɛsenja de go na di ples usay i nid fɔ gi in mɛsej, dɛn kin blok da ples de (risɛptɔ). afta dat di wok we da "calming" sistεm (Parasympathetic) de du de rεdכks sכmtεm.
Fɔ tɔk am simpul wan, anticholinergic mɛrɛsin dɛn kin blok di akshɔn fɔ sɔm tɛm we wan mɛsenja we de kɔntrol di rilaks ɛn kolm prɔses na wi bɔdi.
Us kayn sik dɛn kin yuz dis mɛrɛsin fɔ?
I pas 600 mɛrɛsin dɛn we gɛt anticholinergic prɔpati. Sɔm mɛrɛsin dɛn we dɛn mek fɔ tek advantej pan dis anticholinergic prɔpati fɔ trit sik dɛn. Sɔm mɛrɛsin dɛn gɛt dis prɔpati as sayd ɛfɛkt.
Insay di tebul we de dɔŋ ya, lɛ wi luk pan sɔm kayn mɛrɛsin dɛn we kin yuz dis anticholinergic prɔpati fɔs fɔ trit sik dɛn.
| Nem fɔ di mɛrɛsin (ɛgzampul) . | Yuz kes ɛn wan simpul ɛksplen |
|---|---|
| Atropin we gɛt di sik | Dis na drɔg we dɛn kin yuz bɔku tɛm na di Imejɛnsi Dipatmɛnt (ETU). Dɛn kin yuse am fɔ trit bradycardia we di at rit tu slo, ɛn as tritmɛnt fɔ pɔyzin frɔm sɔm peshɛnt sayd dɛm. If pɔyzin apin, yu dɔktɔ go kɔntak di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Nashɔnal Ospital fɔ gɛt mɔ advays. |
| Ipratropium / Tiotropium we gɛt di sik | Dɛn tin ya kin de na inhala dɛn we dɛn kin gi pipul dɛn we gɛt sik dɛn we de mek dɛn nɔ ebul fɔ blo lɛk asma ɛn COPD. Dɛn mɛrɛsin ya kin ɛp fɔ mek di say dɛn we di briz de blo big ɛn mek i izi fɔ blo. |
| Oksibutinin / Sɔlifenasin | Dɛn kin gi dɛn tin ya fɔ trit urge incontinence, we na wan sik we yu fɔ pis bɔku tɛm ɛn i nɔ kin izi fɔ yu fɔ kɔntrol di we aw yu de pis. Dɛn mɛrɛsin ya kin wok bay we dɛn kin mek di mɔsul dɛn we de na di blad nɔ kɔntrakt. |
| Skɔpolamin | Dɛn kin yuse dɛn tin ya fɔ trit vɔmit ɛn nɔys we kin kam we pɔsin de travul na bɔs ɛn ship (moshɔn sik). Sɔntɛnde, dɛn kin kam lɛk pat. |
| Bεnztropin / Trihεksifεnidil | Dis mɛrɛsin de ɛp fɔ kɔntrol di sayn dɛm lɛk fɔ shek shek wae de kam wit Pakinsin sik. |
| Difenhaydramin we dɛn kɔl | Bɔrku mɛrɛsin wae dɛn kin yuse fɔ alɛji (e.g., piritan) gɛt dɛn tin ya. Dis anticholinergic prɔpati na di men rizin wae mek yu fil slip ɛn gɛt dray mɔt we yu de tek dɛn tin ya. |
Mɛrɛsin dɛm wae gɛt dis prɔpati as sayd ɛfɛkt
Sɔm mɛrɛsin dɛn de we, pan ɔl we dɛn men wok na ɔda tin, dɛn gɛt anticholinergic ifɛkt as sayd ɛfɛkt.
- Sɔm ol mɛrɛsin wae dɛn kin yuse fɔ trit sik lɛk pwɛl hat (Tricyclic antidepressants). Sɔm mɛrɛsin (`Antipsychotic medications`) dɛn kin gi fɔ siriɔs maynd sik lɛk skizofrenia .
- Bɔku mɛrɛsin fɔ alɛji (`Antihistamines`).
Wetin na di sayd ɛfɛkt dɛm fɔ di anticholinergic mɛrɛsin dɛm?
Naw yu go dɔn ɔndastand wetin mek dɛn mɛrɛsin ya kin mek yu mɔt dray ɛn yu nɔ kin si fayn. We wi ridyus di aktiviti fɔ da "calming" sistɛm de, bɔku pan di tin dɛm we da sistɛm de kɔntrol de afɛkt.
Wan Inglish prɔvab de we dɔktɔ dɛn kin yuz fɔ mɛmba dɛn sayd ɛfɛkt ya. "Hɔt lɛk hare, blaynd lɛk bat, dray lɛk bon, rɛd lɛk bit, mad lɛk hat". Dis min se "Hɔt lɛk hare, blaynd lɛk bat, dray lɛk bon, rɛd lɛk bitrut, mad lɛk hat" . Dis kin mek am izi fɔ mɛmba di men sayd ɛfɛkt dɛn.
Lɛ wi tek wan simpul luk pan dɛn sayd ɛfɛkt ya ɛn dɛn kɔz na di tebul we de dɔŋ ya.
| Sayd Ifɛkt we i kin gɛt | Fɔ tɔk am simpul wan, wetin kin apin? |
|---|---|
| Dray mɔt & yay | di "kalm" sistεm de mek di saliva εn kray wata. We i nɔ de wok bɛtɛ, di saliva ɛn kray wata sɛf nɔ kin kɔmɔt bɛtɛ. |
| Di vishɔn we nɔ klia | di mכsul dεm we de chenj di sayz fכ di pupil de afekt, we de mek i at fכ si tin dεm nia. di pupil dεm de bi big (dilated pupils). |
| I nɔ izi fɔ pis (Urinary retention) . | As di blad mכsul dεm nכ de fleksibul, i kin at fכ ɛmti di blad kכmplit wan. |
| Banbɛlɛ | di intestinal muvmεnt we riliyt to di dijestiv prכsεs de slo dכn. |
| At bit kwik kwik wan (Tachycardia) . | di hat rit de inkrεs pas di nכmal lεvεl biכs di "brek" we de kכntro di at bit de wik. |
| Kɔnfyushɔn / Altered mental stetɔs | Asetilkolin impɔtant bak fɔ mɛmori ɛn tink prɔses na di bren. We i ambɔg, mɔ pan pipul dɛn we dɔn ol, i kin mek dɛn kɔnfyus. |
| Haypatɛmmia & Flushed skin | Swet na we fɔ mek di bɔdi kɔntrol di tɛmpracha. Dɛn mɛrɛsin ya kin mek yu nɔ swet, we kin mek yu bɔdi wam. |
Us tɛm yu nid fɔ go to dɔktɔ?
If dɛn dɔn gi yu wan mɛrɛsin we de mek yu nɔ gɛt di sik, di bɛnifit dɛn we yu go gɛt we yu tek am, pas di bad tin dɛn we go apin to yu. Bɔt if yu gɛt ɛni wan pan dɛn tin ya, mek shɔ se yu tɔk to yu dɔktɔ.
- If yu sik nɔr de fil fayn wit mɛrɛsin.
- If yu gɛt prɔblɛm fɔ tek di mɛrɛsin lɛk aw di dɔktɔ tɛl yu (e.g., if yu gɛt prɔblɛm bikɔs ɔf di sayd ɛfɛkt dɛn).
- If di sayd ɛfɛkt dɛm we di mɛrɛsin gɛt bad bad wan fɔ ambɔg yu ɛvride aktiviti dɛm (go wok, drayv, stɔdi).
Imajin, yu gɛt asma, ɛn di inhala we dɛn gi yu de mek am izi fɔ blo, bɔt yu mɔt rili dray. Ɔ i nɔ kin izi fɔ yu fɔ kɔntrol yu urine ɛn di mɛrɛsin we dɛn kin gi yu kin mek yu si smɔl. If na so i bi, we yu tɔk to yu dɔktɔ, i kin chenj di doz fɔ di mɛrɛsin ɔ gi yu ɔda mɛrɛsin we go gi di sem tin.
Di tin we impɔtant pas ɔl na dat, if yu gɛt prɔblɛm, nɔ stɔp fɔ tek yu mɛrɛsin ɔ chenj di doz fɔ yusɛf. Tɔk to yu dɔktɔ ɔltɛm ɛn fala dɛn advays.
Mɛsej we dɛn kin kɛr go na os
- di anticholinergic mεdikeshכn dεm de wok bay we dεn de blכk di akshכn fכ wan kεmikכl mεsenja (Acetylcholine) we de wok insay wi bכdi in "kalm" sistεm.
- Dɛn kin yuz dis mɛrɛsin fɔ mɛn bɔku sik dɛn lɛk asma, Pakinsin sik, ɛn we pɔsin nɔ kin ebul fɔ urinate.
- Sɔm mɛrɛsin fɔ alɛji ɛn pwɛl hat kin gɛt dis anticholinergic prɔpati bak as sayd ɛfɛkt.
- Di sayd ɛfɛkt dɛn we kin apin na we yu mɔt kin dray, yu nɔ kin si fayn, yu bɛlɛ kin pwɛl, yu at kin bit kwik kwik wan, ɛn yu kin kɔnfyus.
- If yu de wɔri bɔt di sayd ɛfɛkt dɛm fɔ wan mɛrɛsin we yu de tek, nɔ fred fɔ tɔk bɔt am ɔ disayd fɔ yusɛf, bɔt fɔ tru, tɔk to yu dɔktɔ.
💬 Comments (0)
No kɔmɛnt nɔ de yet. Ad yu kɔmɛnt ya fɔ di fɔs tɛm.
Ad yu kɔmɛnt