Atezolizumab vaysin fɔ kansa tritmɛnt: Wetin yu nid fɔ no!

We dɔktɔ tɛl yu ɔr pɔrsin wae yu sabi gɛt mɛdikal sik lɛk kansa, yu kin gɛt bɔrku kwɛstyɔn ɛn frayd bɔt de mɛrɛsin wae dɛn go gi yu. Na nɔmal tin fɔ tink bɔt tin dɛn lɛk, "Wetin na dis mɛrɛsin? Aw i go afɛkt di bɔdi? Sɔm sayd ɛfɛkt go de?" Tide wi go tɔk bɔt wan vaysin we dɛn kɔl `(Atezolizumab)` we dɛn kin yuz fɔ trit sɔm kayn kansa. Yu kin dɔn yɛri bak bɔt in brand nem `(Tecentriq)`. Lɛ wi tɔk bɔt dis mɛrɛsin na simpul we we yu go ɔndastand.

Us kayn mɛrɛsin na ``(Atezolizumab)''? Us sik dɛn dɛn kin yuz am fɔ?

Fɔ tɔk am simpul wan, `(Atezolizumab)` na vaksin we de pan wan spɛshal klas ɔf drɔgs we dɛn kɔl `(monoclonal antibody)`. Naw yu kin de wɔnda wetin na `(monoclonal antibody)`. Imajin se wi bכdi gεt wan imyun sistεm we dεn kכl `(imyun sistεm). I tan lɛk ami we de protɛkt wi kɔntri. Dis ami de fɛt ɛnimi dɛn lɛk jem ɛn kansa sɛl dɛn we de mek pɔsin gɛt sik. Bɔt sɔntɛnde, dɛn kansa sɛl dɛn ya kin rili kɔni. Dɛn kin yuz difrɛn we dɛn fɔ ayd frɔm wi ami.

dis na di say we dכg dεm lεk `(Atezolizumab)` de kam in. Wetin dis dכg de du na fכ εp wi imyun sistεm in "sכlda dεm" (i.e. T-sεl dεm) fכ no dεn triki kεnsar sεl dεm ya εn atak dεm. Dis min se dis drɔg de blok di we fɔ mek wi bɔdi in yon difens sistɛm fɛt kansa.

Naw lɛ wi si us kayn kansa dɛn kin yuz dis mɛrɛsin mɔ fɔ:

• Yurothelial cancer: Dis na kansa we de kam na di urinary tract.
• Liva kansa (hepatocellular carcinoma): Kansa we de bigin na di sεl dεm na di liva.
• Lɔng kansa: Dɛn kin yuz dis fɔ difrɛn kayn lɔng kansa.
• Skin kansa (melanoma): Dis na wan kayn kansa we denja we kin kam na di sɛl dɛn na di skin we de mek di kɔlɔ.

Apat frɔm di kayn kansa dɛn we wi dɔn tɔk bɔt, sɔntɛnde yu dɔktɔ kin gi yu dis mɛrɛsin fɔ ɔda sik dɛn. So, if dɛn de gi yu dis mɛrɛsin, i rili impɔtant fɔ aks yu dɔktɔ klia wan wetin mek ɛn aw i go ɛp yu sik.

Wetin na di impɔtant tin dɛn we yu fɔ tɛl yu dɔktɔ bifo yu tek mɛrɛsin?

Bifo yu bigin fɔ trit yu wit `(Atezolizumab)`, i impɔtant fɔ tɛl yu dɔktɔ bɔt yu kɔmplit wɛlbɔdi kɔndishɔn. Dis na bikɔs dɛn fɔ tek spɛshal kia we dɛn de gi dis mɛrɛsin to pipul dɛn we gɛt sɔm sik dɛn. Na sɔm pan dɛn kayn tin ya:

• Di sik dɛn we pɔsin kin gɛt we i de fɛt insɛf:If yu gɛt sik we yu bɔdi in imyun sistɛm de atak yu yon bɔdi, lɛk Crohn’s disease (we na wan sik we de mek yu gɛt inflammatory na di dijestiv trakt), ulcerative colitis (wan inflammatory condition of the big intestine), ɔ lupus (wan sik we de afɛkt yu skin, joyn, ɛn kidni), mek shɔ se yu tɛl yu dɔktɔ. Bikɔs Atezolizumab de afɛkt di imyun sistɛm, dɔktɔ dɛn kin tek tɛm bad bad wan we dɛn de gi am to pɔsin we gɛt dɛn sik ya.
• If yu dɔn gɛt ɔ yu de plan fɔ gɛt allogeneic stem cell transplant: Dis min se if yu dɔn gɛt stem cell frɔm ɔda pɔsin we dɛn transplant insay yu, ɔ if yu plan fɔ du am tumara bambay, tɛl wi bɔt am.
• Wan histri bɔt ɔgan transplant: If yu dɔn gɛt ɔgan transplant (lɛk kidni ɔ liva) bifo.
• If yu dɔn gɛt redyushɔn tritmɛnt to yu chɛst: I impɔtant bak if yu dɔn gɛt redyushɔn tritmɛnt to yu chɛst trade.
• Prɔblɛm na yu nervɔs sistɛm: If yu gɛt wan sik we de ambɔg yu nervɔs sistɛm, lɛk myasthenia gravis (na sik we de mek di mɔsul dɛn wik) ɔ Guillain-Barre syndrome (na sik we de afɛkt di nervɔs).
• Alɛji: If yu gɛt alɛji (alɛji) to Atezolizumab, ɛni ɔda mɛrɛsin, it, day, ɔ prɛzɛvɛtiv, yu fɔ tɛl wi.
• If yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ: Dis na pɔynt we rili impɔtant. Wi go tɔk mɔ bɔt dis leta.
• If yu na mama we de gi pikin in bɛlɛ: Dis na sɔntin bak we yu fɔ rili tek tɛm wit.

I bɛtɛ fɔ tɛl yu dɔktɔ bɔt ɛni wɛlbɔdi prɔblɛm we yu gɛt ɔ ɛni ɔda mɛrɛsin we yu de tek, ilɛksɛf dɛn nɔ de pan dis list.

Aw yu kin yuz dis mɛrɛsin?

dis mεdisin `(Atezolizumab)` dεn kin gi am as injεkshכn insay wan vein (intravenכs infushכn) . Fɔ tɔk am simpul wan, na di mɛrɛsin we de go insay yu bɔdi tru wan vein, jɔs lɛk aw yu go gi sɔl sɔlvushɔn. Dis kin tek lɛk af awa so, bɔt sɔntɛnde i kin tek mɔ ɔ smɔl.

Di impɔtant tin na dat dis nɔto mɛrɛsin we yu kin gi yu na os. Dɛn kin du dis tritmɛnt na ɔspitul, spɛshal klinik fɔ pipul dɛn we gɛt kansa, usay dɔktɔ ɔ nɔs we dɛn dɔn tren de.

Bifo ɛvri tritmɛnt sɛshɔn, yu dɔktɔ ɔ nɔs go gi yu wan spɛshal liflet we dɛn kɔl ``MedGuide'' . I gɛt rili impɔtant tin dɛn bɔt dis mɛrɛsin, di sayd ɛfɛkt dɛn we yu kin gɛt, ɛn tin dɛn we yu fɔ no bɔt. So, i impɔtant fɔ tek tɛm rid ɛn ɔndastand am ɛvri tɛm. Nɔ shem fɔ aks if ɛnitin de we yu nɔ ɔndastand.

Fɔ smɔl pikin dɛnIf yu de gi dis mɛrɛsin, yu fɔ tɔk to dɔktɔ we de mɛn pikin dɛn bɔt am ɛn fala dɛn advays, bikɔs dɛn kin nid spɛshal kia ɛn di doz kin difrɛn.

Wetin a go du if a tek bɔku mɛrɛsin? Wetin a go du if a mis wan doz?

Bikɔs dɛn kin gi dis mɛrɛsin ɔnda dɔktɔ in sɔpɔtishɔn, di risk fɔ mek dɛn tek am pasmak nɔ kin bɔku. Bɔt if yu tink se yu go dɔn drink pasmak, ɔ if yu fil se yu sik pasmak, yu fɔ go na di imejensi rum we de nia yu ɔ kɔl pɔyzin kɔntrol sɛnta wantɛm wantɛm.

I rili impɔtant fɔ tek dis mɛrɛsin di de dɛn we dɛn dɔn sɛtul ɛn di tɛm we dɛn dɔn sɛtul. If yu nɔ ebul fɔ tek yu mɛrɛsin di de we dɛn dɔn sɛtul, ɔ if yu mis wan doz, kɔl yu dɔktɔ ɔ klinik wantɛm wantɛm ɛn mek dɛn no. Dɛn go tɛl yu wetin fɔ du nɛks. Nɔ ɛva chenj yu tritmɛnt schedule we yu want.

Wetin na di spɛshal tin dɛn we yu fɔ tek tɛm wit we yu de yuz dis mɛrɛsin?

Dɔktɔ dɛn go tek tɛm wach yu wɛlbɔdi we yu de tek Atezolizumab.

• Test ɔltɛm: Yu go nid fɔ du blɔd wok ɔltɛm ɛn ɔda tɛst fɔ wach yu kɔndishɔn, si aw di mɛrɛsin de afɛkt yu bɔdi, ɛn si if ɛnitin de afɛkt ɔgan dɛn lɛk di liva ɛn kidni.
• Bεlε εn we yu de gi pikin milk (dis rili impɔtant!):
• If yu na uman, yu fɔ avɔyd fɔ gɛt bɛlɛ ɔltogɛda we yu de tek dis mɛrɛsin (Atezolizumab) ɛn fɔ at le 5 mɔnt afta yu dɔn stɔp di tritmɛnt. Dis rili impɔtant, bikɔs dis mɛrɛsin kin rili ambɔg di pikin we nɔ bɔn yet.
• If yu de op fɔ bɔn pikin, ɔ if yu tink se yu go gɛt bɛlɛ, tɛl yu dɔktɔ wantɛm wantɛm, ɛn nɔ de te. Tɔk to yu dɔktɔ bɔt di rayt we fɔ kɔntrol di pikin.
• Dɔn bak, yu fɔ avɔyd fɔ gi yu pikin in bɛlɛ we yu de tek dis mɛrɛsin, ɛn fɔ at le 5 mɔnt afta di las doz. Dis prɛkoshɔn impɔtant bikɔs dis mɛrɛsin kin pas to di pikin tru in mama in milk.

If yu want fɔ no mɔ bɔt dis, nɔ ɛva fred fɔ aks yu dɔktɔ ɔ fama.

Mɛmba se: Dis mɛrɛsin na fɔ yu nɔmɔ. Nɔ ɛva sheb dis mɛrɛsin wit ɔda pɔsin, ilɛksɛf dɛn gɛt di sem sik lɛk yu.

Wetin na di sayd ɛfɛkt dɛm we dis mɛrɛsin kin gɛt? (`Sayd Ifɛkt dɛn`)

Lɛk ɛni mɛrɛsin, `(Atezolizumab)` kin mek sɔm pipul dɛn gɛt sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn, ɛn aw dɛn kin tranga kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin. Di tin we impɔtant pas ɔl na fɔ no bɔt dɛn sayd ɛfɛkt ya ɛn tɛl yu dɔktɔ if yu gɛt ɛnitin fɔ wɔri bɔt.

Siriɔs sayd ɛfɛkt dɛn we yu fɔ tɛl yu dɔktɔ bɔt wantɛm wantɛm:

If yu gɛt ɛni wan pan dɛn sayn ya, go to yu dɔktɔ wantɛm wantɛm.Okay, wi nid fɔ notis di imejensi rum:

• Alɛji riakshɔn: Skin de rɔsh, ayv, it ɔlsay na di bɔdi, swel na di aylid, lip, tɔŋ ɔ fes, i nɔ izi fɔ blo, di chɛst tayt.
• Prɔblɛm dɛn we de na di dijestiv sistɛm:
• Blak, tar stɔl (dis kin bi sayn fɔ blɔd na di intestinal).
• Blɔd ɔ wata dayarɛa , bɛlɛ pen bad bad wan.
• I nɔ kin izi fɔ yu fɔ blo: Nyu we yu bigin fɔ blo shɔt, yu kin kɔf mɔ ɛn mɔ, yu kin gɛt pen na yu chɛst.
• Chenj we yu de si: Yu nɔ de si fayn wantɛm wantɛm, yu de si tin dɛn tu.
• Chɛst pen ɔ chɛst tayt .
• Chil, fiva .
• Fɔ mek yu fes flash .
• Di ed we kin at bad bad wan .
• Sayn ɛn simptom dɛm fɔ ay blɔd shuga: Tɔsti pasmak , yu mɔt dray, yu de pis bɔku tɛm, yu angri pasmak, yu de tɔn ed, yu skin de dray, yu de smɛl frut wit briz, yu nɔs, yu bɛlɛ de pen.
• Sayn ɛn simptom dɛm fɔ di liva injuri: yu yay ɔ yu skin kin yɔlɔ, yu urine kin dak yɔlɔ ɔ brawn, yu kin gɛt layt kɔlɔ, yu nɔ kin want fɔ it, yu kin nɔs, yu kin fil pen na di ɔp rayt say na yu bɛlɛ, yu kin taya pasmak, ɛn yu kin fil se yu nɔ fayn lɛk fiva.
• Bɔl pen bad bad wan .
• I nɔ izi fɔ pis: yu nɔ de pis igen, blɔd de na di pis, pen we yu de pis.
• Ɔda siriɔs sayn dɛm: yu jɔyn dɛn kin pen bad bad wan, yu mɔsul dɛn kin wik bad bad wan, yu skin kin gɛt blista ɔ sos, yu kin kɔnfyus, ɛn yu nɔ kin no natin.

Sayd ɛfɛkt dɛn we nɔ kin siriɔs, bɔt yu fɔ ripɔt to yu dɔktɔ if dɛn kɔntinyu fɔ de:

Dɛn sayd ɛfɛkt ya nɔ kin siriɔs, bɔt if dɛn kɔntinyu ɔ de mɔna yu, tɛl yu dɔktɔ :

• Bɔn pen
• Kɔf
• Nɔmal dayarɛa (we nɔ gɛt blɔd) .
• Pen na di jɔyn dɛn
• Mɔsul dɛn kin pen ɔ wikɛd
• Di an ɔ leg dɛn we de swel
• We pɔsin taya
• We yu de lɔs yu wet

Dis list nɔ de inklud ɔl di sayd ɛfɛkt dɛn. If yu gɛt ɛni ɔda sayn we nɔ kɔmɔn, tɔk to yu dɔktɔ bɔt am.

Dis mɛrɛsin kin miks wit ɔda mɛrɛsin? (`Drug Intarakshɔn`)

Dis mεdisin we dεn kכl ``(Atezolizumab)`` dεn nכ dכn stכdi am gud gud wan yet pan aw i de intarakt wit כda mεdikeshכn dεm. Dat na,Dis min se i kin bi se dis kin intarakt wit ɔda mɛrɛsin dɛn we yu de tek, ɔr i kin chenj di we aw dɛn mɛrɛsin dɛn de wok.

So, bifo yu bigin dis tritmɛnt, yu fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek naw – nɔto jɔs di wan dɛn we yu dɔktɔ gi yu, bɔt di wan dɛn we yu de bay na di famasi (e.g. pen kil, kol mɛrɛsin), tradishɔnal mɛrɛsin, ɔyl, vaytamɛn, it sɔpɔtmɛnt, ɛn ɔda tin dɛn I impɔtant bak fɔ tɛl yu dɔktɔ if yu de smok, drink rɔm, ɔ yuz ɔda mɛrɛsin dɛn we nɔ rayt. Dis na bikɔs sɔm tin dɛn kin afɛkt di we aw dis mɛrɛsin de wok. Dɔn di dɔktɔ kin du di tin dɛn we i nid fɔ du dat.

Usay yu kin kip di mɛrɛsin?

Yu nɔ nid fɔ wɔri bɔt dis. Bikɔs, `(Atezolizumab)` nɔto mɛrɛsin we yu kin kɛr go na os. Dɛn kin kip am na ɔspitul ɔ klinik tritmɛnt fɔ kansa spɛshal we ɛn dɛn kin gi yu we yu nid am. So yu nɔ nid fɔ wɔri fɔ kip am na os.

Fɔ dɔn, mɛmba dis (Take-Home Message) .

Okay, so a tink se yu dɔn pik sɔm impɔtant pɔynt dɛn frɔm wetin wi dɔn tɔk bɔt wit di `(Atezolizumab)` vaysin. Mɛmba se dis na impɔtant tin we dɛn dɔn fɛn pan advans mɛrɛsin we go ɛp yu fɔ fɛt kansa. Bɔt i rili impɔtant fɔ no bɔt di tin dɛn we wi nid fɔ tek tɛm wit we wi de yuz dis kayn pawaful mɛrɛsin, ɛn di bad tin dɛn we kin apin to wi.

If yu gɛt ɛni kwɛstyɔn ɔ ivin smɔl dawt bɔt dis mɛrɛsin, di tritmɛnt, ɔ di sayd ɛfɛkt dɛn, nɔ ɛva fred ɔ shem fɔ aks yu dɔktɔ, nɔs, ɔ fama. Dɛn de fɔ ɛp yu ɛn ansa yu kwɛstyɔn dɛn.

Fɔ fala di dɔktɔ in instrɔkshɔn dɛn ɛksaktɔli ɔlsay na yu tritmɛnt. Go na di klinik pan di de dɛn we dɛn dɔn sɛtul, mek dɛn du di tɛst dɛn we yu nid. Dɔn yu go ebul fɔ gɛt di bɛst pan dis tritmɛnt ɛn wɛl kwik kwik wan. A de wish yu fɔ wɛl kwik kwik wan!

` Atezolizumab, kansa drɔg, monoklɔnal antibodi, Tecentriq, kansa tritmɛnt, sayd ifɛkt, urothelial kansa