Lɛ wi lan bɔt Metformin, we dɛn kin yuz fɔ dayabitis? (Bigwanide dɛn) .

We yu dɔktɔ tɛl yu se yu gɛt dayabitis, di fɔs mɛrɛsin we dɛn go mɔs gi yu na Mɛtfɔmin. Dis na mɛrɛsin we pipul dɛn lɛk ɛn we nɔ bad fɔ dayabitis, nɔto jɔs na Sri Lanka, bɔt ɔlsay na di wɔl. Bɔt i nɔmal fɔ lɛ wi ɔl gɛt sɔm kwɛstyɔn dɛn ɛn fred smɔl we wi de bigin fɔ tek nyu mɛrɛsin. Yu kin de wɔnda tin dɛm bak lɛk, "Wetin go apin wit dis?", "Dis gud fɔ di bɔdi?", "Ɛni sayd ɛfɛkt de?" Nɔ wɔri, tide wi go tɔk bɔt dis klas ɔf mɛrɛsin we dɛn kɔl Metformin, dat na, Biguanides, insay wan rili simpul we we yu go ɔndastand.

Fɔ tɔk am simpul wan, wetin na dɛn Biguanides ya?

Biguanides na wan klas fɔ mɛrɛsin we dɛn kin yuz fɔ kɔntrol dayabitis. Dɛn kin tek dɛn insay pil fɔm. Dɛn kin yuse dɛn mɔ fɔ trit pipul dɛn we gɛt Tayp 2 Dayabitis . Di men wok we dɛn mɛrɛsin ya de du na fɔ mek di shuga ɔ glukɔs we de na yu blɔd go dɔŋ ɛn kɔntrol am.

Naw yu kin de tink se, "Bɔku drɔgs de na di Biguanides grup?" Nɔto fɔ tru. Naw, na bɔku kɔntri dɛn na di wɔl, inklud Sri Lanka, na wan drɔg nɔmɔ de ɔnda dis grup. Dat na di Metformin we wi ɔl no. Bɔt yu kin si di mɛrɛsin we dɛn kɔl Metformin ɔnda difrɛn brand nem dɛn. Fɔ ɛgzampul:

• Glukofaj® we dɛn kɔl
• Glukofaj XR® we dɛn kin yuz
• Glumetza® we dɛn kɔl Glumetza
• Fortamet® we gɛt fɔ du wit am
• Riomet® we gɛt fɔ du wit am

I nɔ mata us nem i gɛt, di aktif tin we de insay na di sem, we na Metformin.

Dɛn kin gi mɛtfɔmin fɔ dayabitis nɔmɔ?

Metformin na di fɔs tin we dɛn gri fɔ du fɔ tayp 2 dayabitis. Infakt, dɛn kin tek am as fɔs layn tritmɛnt fɔ dat. Dat min se na di fɔs mɛrɛsin we dɔktɔ go bigin wit as soon as dɛn no se i gɛt dayabitis.

Bɔt dɔktɔ dɛn de gi dis mɛrɛsin fɔ sɔm ɔda sik dɛn, nɔto jɔs dayabitis. Wi de kol dis "off-label" yus. Dat min se, dɔktɔ dɛn de gi di mɛrɛsin fɔ ɔda sik dɛn apat frɔm di wan we dɛn ɔfishal gri fɔ, bikɔs i de wok fayn.

Apat frɔm dat, di wan dɛn we de stɔdi bɔt dis de chɛk naw if mɛtfɔmin gɛt tin dɛn we de mek i nɔ gɛt kansa. Sɔm stɔdi dɔn sho se pipul dɛm wae de tek mɛtfɔmin fɔ gɛt dayabitis nɔr kin gɛt kansa. Bɔt dɛn tin ya stil de na di risach stej.

Aw dis Metformin pil kin rili wok insay wi bɔdi?

Dis na kwɛstyɔn we rili impɔtant. Tu men we dɛn de we dis mɛrɛsin de wok. Lɛ wi ɔndastand am wit wan simpul ɛgzampul.

Imajin se yu gɛt big faktri insay yu bɔdi we de mek shuga (glukɔs). Dat na yu liva . Insay pɔsin we gɛt dayabitis, dis faktri kin wok pasmak, ɛn dɛn kin pɔmp shuga ɔltɛm na in blɔd.

1. fכ ridyus di shuga we di liva de mek: di fכs tin we Metformin de du na fכ ridyus di shuga we di liva de mek (di liva). In ɔda wɔd, dis mɛrɛsin de kɔntrol di shuga we nɔ nid fɔ ad to di blɔd we kɔmɔt na di liva.

2. di mכsul dεm kin bi mכr sεnsitiv to insulin: Di sεkכn tin na fכ εp di כmon insulin na wi bכdi fכ wok fayn fayn wan. Insulin tan lɛk ki fɔ di domɔt dɛn na wi bɔdi in sɛl dɛn. Dis ki na in de mek di shuga we de insay di blɔd go insay di sɛl dɛn ɛn mek ɛnaji. Pipul wae gɛt shuga kin gɛt prɔblɛm fɔ opin dis ki. Wi de kɔl amInsulin rɛsistɛns. mεtfכmin de wok bay we i de mek di dכn dεm fכ di sεl dεm lεk mכsul dεm fכ tek dis ki (insulin). Dɔn di shuga we de na di blɔd kin izi fɔ go insay di sɛl dɛn ɛn chenj am to ɛnaji. Dɔn di shuga we de na di blɔd kin go dɔŋ.

pan uman dεm we gεt PCOS, Metformin de lכs di insulin lεvεl, we in tכn de ridyus di lεvεl כf כmon lεk andrכjen, we de εp fכ mek di mεnstral saykl dεm we de kכmכt bak.

Wetin na di bɛnifit dɛn we dis mɛrɛsin de gi?

Metformin na wan mɛrɛsin we rili wok.

• Fɔ lɛ di A1C lɛvɛl dɔŋ: Fɔ pɔsin we gɛt dayabitis, mɛtfɔmin kin mek dɛn A1C lɛvɛl (wan tɛst we de sho di avɛrej blɔd shuga lɛvɛl fɔ di pas 2-3 mɔnt) dɔŋ bay lɛk 1%. Dis na big big tin we dɛn dɔn mek fɔ mɛn pipul dɛn we gɛt dayabitis.
• Fɔ mek yu nɔ gɛt dayabitis: Stɔdi dɔn sho se dis mɛrɛsin kin ɛp fɔ delay ɔ fɔ mek yu nɔ gɛt ful-blɔd dayabitis pan pipul dɛn we gɛt prɛdiabɛtis.
• Fɔ ridyus di risk fɔ gɛt at sik: Sɔm stɔdi dɔn sho se mɛtfɔmin kin ridyus di risk fɔ gɛt at sik bak.

Di tin we impɔtant pas ɔl na dat bikɔs dis mɛrɛsin na tin we pɔsin kin gɛt fɔ yu layf, i impɔtant fɔ mek yu de tɔk to yu dɔktɔ ɛn tek yu mɛrɛsin ɛn chenj dɛn na yu layf (di it, ɛksesaiz) lɛk aw dɛn tɛl yu. Di mɛrɛsin nɔmɔ nɔ go ebul fɔ kɔntrol dayabitis.

Lɛ wi no bak bɔt di bad tin dɛn we kin apin to wi ɛn di bad tin dɛn we kin apin to wi.

Lɛk ɛni mɛrɛsin, Metformin kin mek sɔm sayd ɛfɛkt. Bɔt bɔku pan dɛn tin ya nɔ siriɔs ɛn nɔto ɔlman kin gɛt dɛn.

Kɔmɔn sayd ɛfɛkt dɛn

Dɛn tin ya kin apin insay di fɔs de ɔ wik afta dɛn dɔn bigin fɔ tek di mɛrɛsin. Dɛn kin go as tɛm de go as di bɔdi de ajɔst to di mɛrɛsin.

• Bɛlɛ we de at: Fɔ blo, nɔs, vɔmit, ɛn mɔ dayarɛa na di sayd ɛfɛkt dɛn we kin apin mɔ. Dis kכndyushכn kin apin pan lεk 30% pan di pipul dεm wae de tek mεtformin.
• Fɔ tek di mɛrɛsin afta yu dɔn it: Di bɛst we fɔ mek yu nɔ fil fayn na yu bɛlɛ lɛk dis na fɔ tek di mɛrɛsin wit yu it ɔ jɔs afta yu dɔn it. Nɔ tek am we yu ɛmti bɛlɛ.

Sɔm sayd ɛfɛkt dɛn we nɔ kin apin so ɔltɛm

• Diskɔmfɔt na di chɛst
• Ed de at
• We yu de swet pasmak (diaphoresis) .
• Lɔw blɔd shuga (haypoglycemia) - (Dis nɔ kin apin so ɔltɛm wit mɛtfɔmin nɔmɔ, bɔt i kin apin we dɛn tek am wit ɔda dayabitis mɛrɛsin)
• Wik

If dɛn tin ya kɔntinyu ɔ mek yu nɔ fil fayn, tɔk to yu dɔktɔ.

Risk dɛn we nid spɛshal atɛnshɔn

Metformin na jɔs wan mɛrɛsin we rili sef, bɔt i impɔtant fɔ no bɔt sɔm siriɔs prɔblɛm dɛn we kin apin smɔl smɔl.

1. Vitamin B12 we nɔ de

We yu tek Metformin fɔ lɔng tɛm, yu bɔdi kin tek vaytamɛn B12 smɔl smɔl. So, yu dɔktɔ kin chɛk yu vaytamɛn B12 lɛvɛl, mɔ if yu gɛt anemia ɔ peripheral neuropathy. If nid de, i kin se yu fɔ tek wan vaytamɛn B12 sɔpɔtmɛnt.

2. Laktik Asidכsis

Laktik asid na wan sik we di bɔdi de bil tumɔs laktik asid, we de mek di blɔd tu asid. Dis sik kin afɛkt lɛk 1 pan ɛvri 30,000 pipul dɛm wae de tek mɛtfɔmin. Dis nɔ kin apin so ɔltɛm. Bɔt, e kin mek yu layf de pan denja, so i impɔtant fɔ no bɔt de sik.

Pipul wae gɛt bɔrku risk fɔ gɛt laktik asid:

• Pipul wae gɛt kidni ɔr liva sik
• Pipul dɛn we dɔn pas 65 ia
• Pipul dɛn we dɛn jɔs du ɔpreshɔn pan
• Pipul wae gɛt haypoksia (we nɔr gɛt ɔksijɛn na dɛn bɔdi) .
• Pipul dɛn we de drink rɔm pasmak

Yu dɔktɔ go de chɛk yu kidni ɔltɛm we yu de gi yu Metformin fɔ akɔntayn dis risk.

Di sayn dɛm fɔ laktik asid:

If wan ɔ mɔ pan dɛn sayn ya apin wantɛm wantɛm, stɔp fɔ tek di mɛrɛsin wantɛm wantɛm ɛn go na di ɔspitul imejensi rum (ETU) we de nia yu.

• I kin taya pasmak ɛn i kin wik
• Nɔs ɛn vɔmit
• Bɛlɛ de at
• Fɔ blo kwik ɔ fɔ lɔng tɛm, dip dip wan

Dis sik kin ivin mek pɔsin day if dɛn nɔ trit am kwik, so na fɔ no bɔt dɛn sayn ya.

3. Prɔblɛm wit ɔda mɛrɛsin dɛn (Drug Interactions) .

If yu de tek mɛtfɔmin ɛn yu de tek ɔda mɛrɛsin fɔ ɔda sik, i impɔtant fɔ tɛl yu dɔktɔ. Sɔm mɛrɛsin kin intarakt wit mɛtfɔmin ɛn mek di risk fɔ gɛt laktik asid bɔku. Sɔm mɛrɛsin kin mek bak di blɔd shuga nɔ bɔku (hypoglycemia). Mek shɔ se yu tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek (inklud vaytamɛn dɛn, sɔpɔtmɛnt dɛn, ɛn ɛbul mɛrɛsin dɛn).

Ustɛm a fɔ go to di dɔktɔ?

We yu de tek mɛtfɔmin, yu fɔ go na di klinik dɛn di tɛm we yu dɔn sɛtul lɛk aw yu dɔktɔ tɛl yu fɔ du. Da we de, i kin si if di mɛrɛsin de wok, if dɛn nid fɔ chenj di we aw dɛn de tek am, ɛn if ɛni bad tin de apin.

Apat frɔm dat, tɔk to yu dɔktɔ pan dɛn tin ya:

• If di sayd ɛfɛkt dɛn de mɔna yu ɔ i at fɔ bia wit.
• If yu fil se yu nɔr de kɔntrol yu dayabitis ɔr PCOS kɔndishɔn fayn fayn wan wit mɛrɛsin.
• If yu fil se yu nid fɔ stɔp fɔ tek di mɛrɛsin fɔ ɛni rizin, nɔ ɛva stɔp fɔ tek di mɛrɛsin we yu nɔ go to yu dɔktɔ.

Metformin na wan mɛrɛsin we rili sef ɛn we de wok fayn we bɔku bɔku pipul dɛn ɔlsay na di wɔl dɔn de yuz fɔ lɔng lɔng tɛm, dɛn dɔn du risach gud gud wan, ɛn pipul dɛn kin gri fɔ tek am fayn fayn wan. So nɔ fred fɔ aks kwɛstyɔn. Fil fri fɔ tɔk to yu dɔktɔ bɔt ɛni kwɛstyɔn ɔ tin we de mɔna yu. I rɛdi ɔltɛm fɔ ɛp yu.