Wetin na di dopamin agonist dɛn? Lɛ wi lan bɔt dɛn drɔgs ya insay simpul wɔd dɛn!

Ɛnibɔdi na yu famili gɛt prɔblɛm wit muvmɛnt lɛk Pakinsin sik? Ɔ yu dɔktɔ dɔn ɛva tɛl yu ɔ pɔsin we yu sabi bɔt wan kayn mɛrɛsin we dɛn kɔl dopamine agonists? Di nem kin tan lɛk se i kɔmplikt smɔl, bɔt nɔ wɔri. Tide wi go tɔk bɔt am na wan rili simpul we we yu go ɔndastand. Rid dis lɛk se yu de tɔk to yu padi.

Fɔ tɔk am simpul wan, wetin na dɛn dopamin agonist ya?

Fɔ ɔndastand dis, lɛ wi lan smɔl fɔs bɔt aw wi bren de wok. Wi gɛt sɛl dɛn na wi nervɔs sistɛm. Dɛn sɛl dɛn ya kin tɔk to dɛnsɛf, ɔ tɔk to dɛnsɛf tru spɛshal kemikal dɛn. Wi kin kɔl dɛn nyurotransmitta ya. Dɛn pipul ya tan lɛk mɛsenja dɛn.

Imajin se wi nɛv sɛl na domɔt we gɛt tɔl insay. Fɔ opin da domɔt de, i nid di rayt ki. Semweso, ɔl sɛl gɛt sɔntin we dɛn kɔl ‘rɛsɛptɔ’ na in fes, jɔs lɛk tɔl. Nyurotransmitta dɛn tan lɛk ki dɛn we fit dɛn tɔl dɛn de. Jɔs lɛk aw we yu put di ki insay, di tɔl opin ɛn di domɔt opin, we di nyurotransmitta kɔnɛkt to di risɛptɔ, di sɛl de wok.

Dopamin na wan impɔtant ki na wi bren, we na nyurotransmitta. We yu lan sɔntin, we yu fil gladi ɛn satisfay, na dis dopamin de mek yu fil dɛn de. Dɔn bak, dopamin impɔtant fɔ mek wi mɔsul dɛn muv fayn fayn wan.

Naw lɛ wi go to wi tɔpik. Wetin na Dopamin Agonist dɛn ? Fɔ tɔk am simpul wan, dɛn mɛrɛsin ya na drɔgs we de wok lɛk dopamine . Fɔ tɔk strikt wan, dɛn nɔto dopamin, bɔt dɛn ful wi bren sɛl dɛn. di shep fכ dεn dכg mכlikul dεm ya so lεk di dopamin mכlekyul dεm dat dεn fit εksakכt insay di rεsεpכta dεm na dεn sεl dεm we wi bin mεnshכn. So, we yu tek dis drɔg, i de go ɛn opin di domɔt dɛn we dopamin nid fɔ opin. In ɔda wɔd, dɛn drɔgs ya de du di sem tin we dopamin de du. Wi sɛl dɛn nɔ no di difrɛns bitwin di tu tin dɛn.

Wetin dopamine de du to wi bɔdi ɛn di mɛdikal kɔndishɔn dɛm wae de yuse dis mɛrɛsin

Dopamine nɔ jɔs de ɛp fɔ mek di mɔsul dɛn muv. I nid bak fɔ kɔntrol bɔku ɔda impɔtant tin dɛn we de apin na wi bɔdi. Fɔ ɛgzampul:

• Di we aw di at de wok
• Di kidni dɛn we de wok
• Pankrias de wok
• Di wok we di pituitary gland de du
• Wi ɛndokrin sistɛm
• Dijestiv sistɛm
• uman ɛn man riprodaktiv sistɛm

So yu go mɔs ɔndastand ɔmɔs prɔblɛm kin kam if di dopamin lɛvɛl na di bɔdi go dɔŋ. Dɛn kin yuz dopamin agonist fɔ trit bɔku tin dɛn we kin apin we pɔsin nɔ gɛt dopamin.

Si di tebul dɔŋ ya fɔ no us kayn mɛrɛsin ya dɛn kin yuz mɔ fɔ.

Wetin na di bɛnifit dɛn we pɔsin kin gɛt we i yuz dɛn mɛrɛsin ya?

Dopamine agonists nɔto jɔs wan kayn mɛrɛsin we dɛn kin gi. Bɔku klia bɛnifit dɛn de we pɔsin kin gɛt we i yuz dɛn.

• Rizult we rili fayn: Risach dɔn pruv se dɛn mɛrɛsin ya kin rili ɛp fɔ mɛn bɔku pan di sik dɛn we wi bin dɔn tɔk bɔt ɔp.
• Dɛn kin yuse am fɔ difrɛn kayn tin dɛm: As yu si, dɛn kin yuse dɛn tin ya fɔ difrɛn kayn tin dɛm, frɔm wae yu bren de muv to wae yu gɛt ɔmon prɔblɛm.
• Fɔ kɔmpitabl wit ɔda mɛrɛsin dɛn: Dis rili impɔtant. fכ egzampl, we dεn gi wan dopamin agonist tכgeda wit di Parkinson in drog ‘Levodopa’, i pכsibul fכ ridyus di doz fכ di levodopa. Ivin wit di doz we smɔl, dɛn kin gɛt mɔ rizɔlt. Dis kin ridyus di sayd ɛfɛkt dɛm bak we di lɛvodopa kin gɛt.
• Layf sev: Insay di denja kɔndishɔn we dɛn kɔl ‘Neuroleptic Malignant Syndrome’ we wi bin tɔk bɔt ɔp, dopamine agonist mɛrɛsin kin ɛp fɔ sev layf.

Risk ɛn prɔblɛm dɛn we kin apin (sayd ɛfɛkt dɛn) .

Lɛk ɛni mɛrɛsin, dopamine agonist kin mek sɔm sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn, ɛn dɛn kin apin mɔ as di doz de go ɔp. I impɔtant fɔ no bɔt dɛn tin ya.

Kɔmɔn sayd ɛfɛkt dɛn

Dɛn tin ya na di sayd ɛfɛkt dɛn we kin apin mɔ:

• Banbɛlɛ
• Diziz we pɔsin kin gɛt
• Ed de at
• Bɛlɛ de pwɛl
• Di at ritm irɛgyulariti (ari ritmia) .
• Nɔs ɛn vɔmit
• We yu tinap wantɛm wantɛm, yu yay kin tɔn blu ɛn yu kin fil lɛk se yu go fɔdɔm (Orthostatic hypotension) .
• Muvmεnt dεm we nכ de kכntro lεk mכsul dεm we de twitch

Di chenj dɛm na yu maynd ɛn bihayvya we kin apin we yu yuz am fɔ lɔng tɛm

We yu de yuz dis mɛrɛsin fɔ lɔng tɛm, sɔm chenj dɛn kin apin na yu maynd ɛn aw yu de biev.

• Mɛmori ɛn tink kɔnfyushɔn
• Pwɛl at
• Impuls kɔntrol ishu dɛn
• Fɔ de du tin ɔ fɔ gladi pasmak (Mania) .
• Sɔm kayn sayn dɛm wae tan lɛk saykosis, lɛk fɔ si ɔr yɛri hallucinations
• Slip pasmak de ɛn slip atak wantɛm wantɛm

Impuls kɔntrol ishu dɛn

Dis na sayd ɛfɛkt we wi fɔ wɔri bɔt mɔ. Bikɔs dopamin gɛt sɔntin fɔ du wit wi gladi ɛn satisfay, we dɛn mɛrɛsin ya de mek dis sistɛm wok, sɔm pipul dɛn nɔ kin ebul fɔ kɔntrol dɛnsɛf igen. Dat min se, dɛn kin tɛmpt dɛn fɔ du tin dɛn we dɛn nɔ ebul fɔ kɔntrol dɛnsɛf.

Imajin, afta pɔsin we nɔmal fɔ no intres pan gambling bigin fɔ yuz dis drɔg, dɛn kin bigin fɔ ple gambling we dɛn nɔ ebul fɔ kɔntrol. Dɛn kin du am te dɛn lɔs ɔl dɛn mɔni. Wan ɔda pɔsin kin fil lɛk fɔ go bay tin dɛn we i nɔ ebul fɔ kɔntrol. Ɔda pipul dɛn bak kin gɛt fɔ du mami ɛn dadi biznɛs pasmak.

Wetin go apin if yu stɔp fɔ tek di mɛrɛsin wantɛm wantɛm? - Dopamin Agonist Witdrawal Sindrom (DAWS) .

Dis na tin bak we rili impɔtant. Nɔ ɛva stɔp fɔ tek dis mɛrɛsin wantɛm wantɛm ɔ ridyus di doz if yu dɔktɔ nɔ advays yu. If yu du dat, i kin mek yu gɛt wan sik we dɛn kɔl Dopamine Agonist Withdrawal Syndrome (DAWS). Dis nɔto adikshɔn to di mɛrɛsin, bɔt na riakshɔn we kin apin we di bɔdi dɔn yus to di mɛrɛsin ɛn stɔp fɔ tek am wantɛm wantɛm.

Insay dis kayn tin, dɛn sayn ya kin apin:

• Wɔri ɛn panik atak
• We yu de swet pasmak (diaphoresis) .
• We pɔsin nɔ de rɛst
• Taya pasmak
• Bɔdi pen
• Vɔmit
• Diziz we yu tinap (Orthostatic hypotension) .

Bɔku tin dɛn de we kin mek di risk fɔ gɛt dis DAWS kɔndishɔn bɔku. Si di tebul we de dɔŋ ya.

Ɛni kes de we dɛn nɔ fɔ tek dɛn mɛrɛsin ya?

Yɛs, sɔm tɛm dɛn de we dɛn mɛrɛsin ya nɔ fayn fɔ yuz. Yu dɔktɔ go tink bɔt ɔl dɛn tin ya bifo yu gi yu di mɛrɛsin. Bɔt i fayn fɔ mek yu no bɔt dis bak.

• We uman gɛt bɛlɛ ɛn we i de gi pikin in mama in bɛlɛ: Dɛn mɛrɛsin ya kin mek pɔsin nɔ gɛt pikin in bɛlɛ, so dɛn nɔ kin se dɛn fɔ gi pikin dɛn milk insay dɛn tɛm ya.
• If yu gɛt ay blɔd prɛshɔn (haypa prɛshɔn): Sɔm dopamin agonist kin mek yu blɔd prɛshɔn go ɔp.
• Risk fכ divεlכp sכm fibrosis-tayp kכndyushכn dεm: Risk de fכ divεlכp kכndyushכn lεk pulmonary fibrosis, spεshal wan wit ol (ergot-based) dopamine agonists.
• Kidni ɔ liva sik: Na di kidni ɛn di liva kin pul di mɛrɛsin dɛn na di bɔdi. Pipul wae gɛt sik na dɛn ɔgan ya kin gɛt dis mɛrɛsin wae de kam na dɛn bɔdi, ɛn dis kin mek dɛn gɛt sayd ɛfɛkt.
• If yu de tek sɔm ɔda mɛrɛsin dɛn: Dɛn nɔ go ebul fɔ tek dɛn mɛrɛsin ya if yu de tek mɛrɛsin dɛn we dɛn kɔl ‘monoamine oxidase inhibitors’ (MAOIs), mɔ di wan dɛn we dɛn kin yuz fɔ mental sik.
• If yu bin dɔn gɛt saykosis bifo: Dɛn pipul ya kin gɛt bɔrku risk fɔ gɛt dɛn kayn sik ya bak wit dɛn mɛrɛsin ya.

Wetin na di difrɛns bitwin Dopamine ɛn Dopamine Agonist?

Wan kin wɔnda, if dopamin nɔ bɔku, wetin mek dɛn nɔ kin gi dopamin insɛf dairekt wan as drɔg, ɛn wetin mek dɛn kin gi drɔg we de akt lɛk dis? Bɔku rizin dɛn de fɔ dat.

1. Blɔd-Bren Baria: Wi bren de tek tɛm bad bad wan. I nɔ de mek ɔltin we de na di blɔd go insay di bren. i gεt wan filta we de protεkt we dεn kכl ‘blכd-bren barεri’. I tan lɛk ‘sekyuriti gad’ fɔ di bren. di dopamin we dεn gi na do nכ kin pas dis sikyɔriti gad εn go insay di bren. Bɔt di dopamin agonist dɛn kin pas dis barɛri ɛn go stret insay di bren.

2. Sayd ɛfɛkt: We dɛn gi dopamin dairekt as injɛkshɔn, i kin mek bɔku sayd ɛfɛkt dɛn we dɛn nɔ want bikɔs i kin afɛkt di wan ol bɔdi. di dopamin agonist dεm dεn mek fכ wok insay wan mכr tכgεt we.

3. Yuz fɔ lɔng tɛm:Insay di sik we dɛn kɔl Parkinson, dɛn kin gi wan mɛrɛsin we dɛn kɔl ‘Levodopa’. I de go insay di bren ɛn tɔn to dopamin. Bɔt as tɛm de go, dɛn nid fɔ ad di doz fɔ da mɛrɛsin de, dɔn di bad tin dɛn we kin apin to am kin bɔku. So, bay we yu yuz dopamin agonist dεm na di fכs stej dεm fכ di sik, i pכsibul fכ delay di stat fכ lεvodopa. Dis kin ɛp di pɔsin fɔ de wɛl fɔ lɔng tɛm.

If dɛn dɔn gi yu ɔ pɔsin we yu sabi dɛn mɛrɛsin ya, nɔ wɔri. Dɛn mɛrɛsin ya na valyu mɛrɛsin dɛn we kin rili ɛp yu fɔ liv yu layf if yu yuz am di rayt we. Di tin we impɔtant pas ɔl na fɔ kɔntinyu fɔ tɔk to yu dɔktɔ ɔltɛm ɛn tɔk opin wan bɔt ɛni prɔblɛm ɔ sayd ɛfɛkt.