Yu na pɔrsin wae gɛt pwɛl hat sik ɔr de tek mɛrɛsin fɔ pwɛl hat? If na so i bi, yu go sabi dis ɛkspiriɛns. Di mɛrɛsin we di dɔktɔ bin gi yu fɔs, di ‘ɔrijinal’ wan we wi ɔl no, kin chenj na di famasi afta sɔm tɛm. Yu kin gɛt di sem mɛrɛsin ɔnda difrɛn nem ɛn insay difrɛn paket. Dis na wetin wi kin kɔl ‘jɛnɛrik’ mɛrɛsin. Wit dis chenj, yu fil lɛk se di filin dɛm fɔ sɔri ɛn wɔri we yu bin gɛt bifo de kam bak? Ɔ di sayd ɛfɛkt dɛn we yu bin gɛt we yu bigin fɔ tek di mɛrɛsin dɔn apia bak? Nɔ wɔri, nɔto yu nɔmɔ de gɛt dɛn tin ya. Lɛ wi tɔk klia wan bɔt dis.
Wetin na di difrɛns bitwin ‘brand-nem’ ɛn ‘jenɛrik’?
Fɔ tɔk am simpul wan, kɔmni we mek nyu mɛrɛsin kin gɛt patɛnt fɔ am. Insay da tɛm de, na da kɔmni de nɔmɔ go ebul fɔ mek da mɛrɛsin de. Wi kin kɔl am ‘brand-nem’ ɔ ɔrijinal drɔg . We dis patɛnt tɛm dɔn, di lɔ alaw ɔda kɔmni dɛn fɔ mek drɔgs we dɛn de yuz di sem aktif ingridiɛnt. Na dat wi kin kɔl ‘jɛnɛrik’ drɔgs .
Big big wɛlbɔdi ɛjɛnshi dɛm ɔlsay na di wɔl, lɛk di Food and Drug Administration (FDA) na Amɛrika, se no big difrɛns nɔ de bitwin di tu kayn. So, bɔku tɛm, dɔktɔ dɛn ɔlsay na di wɔl, ɛn bak na wi kɔntri, kin tɛl pipul dɛn se dɛn fɔ tek mɛrɛsin dɛn we dɛn nɔ gɛt. Na bikɔs dɛn kin tek dɛn as kɔpi dɛn we go wok fayn fɔ di fɔs mɛrɛsin. Ɛn dɛn kin shɔt bak fa fawe.
So wetin mek dis chenj kin afɛkt sɔm pipul dɛn?
Dis na di kwɛstyɔn we bɔku pipul dɛn gɛt. If dɛn tu mɛrɛsin ya na di sem, wetin mek sɔm pipul dɛn kin fil difrɛn we dɛn chenj frɔm di ɔrijinal drɔg to di jenɛrik? Tu men rizin dɛn kin de fɔ dis:
1. De sik kin kam bak: Afta dɛn dɔn chenj to jenɛrik mɛrɛsin, sɔm sik pipul dɛn kin bigin fɔ gɛt dɛn ol simptom dɛm fɔ pwɛl hat, lɛk fɔ fil bad, nɔr gɛt op, ɛn wɔri bak.
2. Sayd ɛfɛkt kin apin bak: Fɔ ɔda pipul dɛn, sayd ɛfɛkt lɛk diziz ɛn nɔys we bin fɔs apia we dɛn bigin di ɔrijinal mɛrɛsin kin bigin fɔ apia bak we dɛn chenj to di jenɛrik.
Imajin dis tin we go apin. Wan pɔsin we nem Samantha bin dɔn de tek di ɔrijinal drɔg `(Paxil)` fɔ pwɛl hat fɔ lɛk wan ia so ɛn i bin de du fayn fayn wan. Bɔt afta di famasi gi am in jenɛrik vɛshɔn we dɛn kɔl `(Paroxetine),` insay sɔm wiks i bigin fɔ fil di sem ol ebi ɛn nɔ intres pan ɛnitin. Ivin ripɔt dɛn de we dɔktɔ dɛn kin gi bɔt dɛn kayn kes dɛn de. Sɔntɛnde, ivin we yu de chenj frɔm wan jenɛrik to ɔda wan, dɛn kayn tin ya kin apin.
Di impɔtant tin na dat dis nɔto "sistɛmatik prɔblɛm" wit jenɛrik drɔgs. Bɔt i impɔtant fɔ mek dɔktɔ dɛn rili wach bɔt dis.
Wetin na di sayɛns we de ɛksplen dis difrɛns?
Bɔku tɛm, di prɔblɛm nɔto dat di jenɛrik drɔg "lɛs" pas di ɔrijinal wan. Bɔt sɔm rili smɔl difrɛns dɛn kin de . Dɛn smɔl smɔl difrɛns dɛn de kin afɛkt sɔm pipul dɛn.
Fɔ tɔk am simpul wan, pil nɔto 100% jɔs di aktif ingridiɛnt. Dɛn kin ad ɔda tin dɛn to di pil fɔ tay am togɛda (binders), kip di shep fɔ di pil, ɛn put kɔtin pan am (coatings). Dɛn kɔl dɛn tin ya ‘nɔ-aktiv ingridiɛnt’ . Dɛn tin ya we nɔ de wok kin difrɛn bitwin di ɔrijinal drɔg ɛn di jenɛrik drɔg. Dis difrɛns kin chenj smɔl di rit we di mɛrɛsin de sɔlv na di bɔdi ɛn di rit we i de absɔb insay di blɔd.
bay di lכ, di lεvεl fכ di drog we wan jεnεrik drog fכ kכmכt na di bכdi in bכdi de bitwin 80% εn 125% fכ di lεvεl we di כrijinal drog de kכmכt. Pan ɔl we dis kin tan lɛk big rɛnj, bɔku pipul dɛn nɔ go ivin notis dis difrɛns. Bɔt fɔ sɔm pipul dɛn we gɛt sɛnsitiv tin, mɔ di wan dɛn we gɛt ɔda mɛrɛsin ɔ we gɛt difrɛn kayn jɛnɛtiks, ivin dis smɔl difrɛns kin afɛkt dɛn.
Di tebul we de dɔŋ ya kin ɛksplen dis difrɛns mɔ.
| Trut | Brand-nem (ɔrijinal) mɛrɛsin | Jɛnɛrik mɛrɛsin |
|---|---|---|
| Aktiv Ingridiɛnt | Na di sem tin ɔltogɛda | Na di sem tin ɔltogɛda |
| Ingridiɛnt dɛn we nɔ de wok | Wan patikyula kɔmbayn de | I kin difrɛn. (e.g., tin dɛn we dɛn kin yuz fɔ tay, kɔva dɛn) |
| Blɔd Lɛvɛl | I gɛt wan patikyula standad | I kin bi bitwin 80% - 125% pan di ɔrijinal |
| Prays | Bɔku tɛm, i kin dia | Bɔku tɛm, i kin shɔt |
Wetin yu fɔ du?
Okay, so if yu fil difrɛns bak we yu chenj to wan jenɛrik drɔg, nɔ wɔri. Sɔm tin dɛn de we yu kin du.
Tɔk to di dɔktɔ.
Dis na di tin we impɔtant pas ɔl ɛn di fɔs tin we yu fɔ du . Tɛl yu dɔktɔ bɔt ɛni chenj we yu notis, ilɛksɛf di sik kam bak ɔ di sayd ɛfɛkt dɛn apin. Bi klia, "Dɔkta, a dɔn notis dis chenj frɔm we a chenj to di nyu mɛrɛsin." Nɔ ɛva stɔp fɔ tek yu mɛrɛsin ɔ chenj di doz fɔ yusɛf.
Ajɔstmɛnt fɔ di Doz
Sɔntɛnde, yu dɔktɔ kin disayd fɔ chenj di mɛrɛsin we yu de tek smɔl. Fɔ ɛgzampul, if yu bin de tek 20mg pan di ɔrijinal drɔg ``(Celexa)`` ɛn yu bin de du wɛl, yu kin nid fɔ tek 30mg ɔ 40mg pan di jenɛrik drɔg ``(Citalopram)`` fɔ gɛt di sem rizɔlt. Na yu dɔktɔ nɔmɔ fɔ disayd dis.
Switch bak to di ɔrijinal mɛrɛsin
If di jenɛrik mɛrɛsin nɔ fayn fɔ yu ɛn yu ebul fɔ pe di prayz fɔ di ɔrijinal mɛrɛsin, yu dɔktɔ kin advays yu fɔ chenj bak to di ɔrijinal mɛrɛsin.
Fɔ dɔn, di jenɛrik antidipreshɔn mɛrɛsin dɛn kin jɔs bi mɛrɛsin dɛn we rili sef ɛn we kin wok fayn. Dɛn nɔ kin dia so, ɛn dis kin mek bɔku pipul dɛn kin ebul fɔ gɛt dɛn. Bɔt jɔs lɛk ɛni mɛrɛsin, i impɔtant fɔ no aw i kin afɛkt yu bɔdi ɛn tɔk to yu dɔktɔ bɔt ɛnitin we de mɔna yu.
Mɛsej we dɛn kin kɛr go na os
- Jɛnɛrik antidipreshan kin jɔs sef ɛn jɔs lɛk di ɔrijinal mɛrɛsin.
- We yu chenj frɔm wan ɔrijinal drɔg to wan jenɛrik, smɔl nɔmba pan pipul dɛn kin gɛt di sik ɔr sayd ɛfɛkt bak. Dis na bikɔs ɔf difrɛns pan di ‘inactive ingredients’ we de insay di pil.
- If yu notis dis kayn chenj, nɔ panik, tɔk to yu dɔktɔ wantɛm wantɛm.
- Yu nɔ fɔ ɛva stɔp fɔ tek mɛrɛsin ɔ chenj di doz if yu nɔ gɛt dɔktɔ advays.
- Tɔk to yu dɔktɔ fɔ no di mɛrɛsin ɛn di doz we go fayn fɔ yu. Yu maynd wɛl bɔdi rili impɔtant.
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