Sɔntɛnde, afta yu it spays it, yu kin gɛt bɔn na yu chɛst, nɔto so? Ɔ yu nɔ kin fil fayn lɛk se yu bɛlɛ asid dɔn bɔku ɛn i de kam ɔp na yu trot? H2 blɔk na wan kayn mɛrɛsin we bɔku pipul dɛn kin yuz sɔm tɛm lɛk dis. So tide, lɛ wi tɔk bɔt wetin na dɛn H2 blɔk ya, aw dɛn de wok na wi bɔdi, ɛn us impɔtant tin dɛn wi nid fɔ no we wi de yuz dɛn.
Wetin na dɛn H2 Blɔka ya?
Fɔ tɔk am simpul wan, H2 blɔk (dɛn kin kɔl am bak H2 antagonist) na wan kayn mɛrɛsin we de kɔntrol ɔ ridyus di prodakshɔn fɔ asid na yu bɛlɛ.
Asid na di bɛlɛ impɔtant fɔ mek wi ebul fɔ digest di it we wi de it. Bɔt if dis asid bɔku, i kin pwɛl di layn na yu bɛlɛ. Dis kin mek yu gɛt sɔm sayn dɛm lɛk bɛlɛ pen ɛn at bɔn. I kin mek yu nɔ fil fayn lɛk we yu rigrɛt fɔ di las it we yu it.
If yu de gɛt diskɔmfɔt bak bikɔs yu bɛlɛ asid dɔn bɔku, yu kin tink bɔt fɔ yuz H2 blɔk.
Us kɔndishɔn dɛn kin yuz H2 blɔk fɔ?
H2 blכk dεm dεn kin yus mεntal fכ trit kכndishכn dεm we riliyt to εksyכs bεlε asid prodakshכn. Bɔt i impɔtant fɔ mɛmba se dɛn mɛrɛsin ya kin lɛf fɔ wok smɔl smɔl if dɛn de yuz dɛn ɔltɛm fɔ lɔng tɛm.
If yu gɛt wan sik we nɔ de mɛn, yu dɔktɔ kin tɛl yu fɔ tek wan kayn mɛrɛsin we dɛn kɔl Proton Pump Inhibitor (PPI) instead of H2 blockers. pan ɔl we PPI dɛn kin tek lɔng tɛm fɔ wok, dɛn kin kɔntrol asid prodakshɔn fayn fayn wan pas H2 blɔk dɛn. Dɛn kin yuz dɛn bak fɔ lɔng tɛm.
Sɔm pan di men kɔndishɔn dɛn we dɛn trit wit H2 blɔk dɛn de dɔŋ ya.
| Mɛdikal kɔndishɔn | Wan simpul ɛksplen |
|---|---|
| Ɔlsa na di bɛlɛ | di asid we pasmak we de kכmכt kin pwεl di layn na di bεlε εn mek yu gεt כlsa. fכ ridyus asid wit H2 blכk dεm de gi dεn כlsa dεm di tεm εn envayroment we dεn nid fכ hεl. |
| Duodenal ɔlsa dɛn | di bכdi asid kin travul go כp insay di fכs pat pan di sכmכl intestכn (duodenum) εn mek כlsa de. Dis kכndyushכn kin trit bak wit H2 blכk dεm, pan כl we PPI dεm kin wok mכr. |
| Asid riflɔks | di bεlε asid de travul bak כp insay di εsophagus εn di trot, we de mek di at bכn. Dis kin mek bak yu gɛt ɛsophagitis. H2 blכka na gud sכlushכn fכ dis wan wan kכndishכn. Bɔt if dis kin apin bɔku tɛm (GERD), PPI kin fayn mɔ. |
| Zollinger-Ellison sindrom we gɛt di sik | Dis na tin we nɔ kin apin so ɔltɛm. sכm tכmכro dεm we de fכm na dis kכndishכn de mek di bεlε de mek tu mכch asid. Pan ɔl we di wan dɛn we de blok H2 kin ɛp fɔ kɔntrol dis sik, bɔku tɛm dɔktɔ dɛn kin se dɛn fɔ yuz PPI. |
H2 blɔk dɛn kin ɛp fɔ pul dɛn sik ya we gɛt fɔ du wit dɛn sik ya:
- Di we aw pɔsin nɔ de it fayn
- Bɛlɛ de pen
- Chɛst pen ɛn trot we de at
- Nɔs ɛn vɔmit
- Sɔl bɛlɛ
Aw dis mɛrɛsin kin rili wok insay di bɔdi?
I rili simpul. כda nem fכ H2 blכk dεm na histamin-2 (H2) antagonist dεm. Wi lan na skul se ‘antagonist’ na stori na sɔntin we de ambɔg sɔntin? wεl, wetin dεn H2 antagonist dεm ya de du na fכ intafεr di prכsεs fכ prodyuz asid na di bεlε.
Tink bɔt am dis we. Afta wi it, wi bɔdi de pul wan kemikal we dɛn kɔl H2. dis H2 de go εn atak di H2 rεsεpכta dεm na di wכl dεm na di bεlε. I tan lɛk ki we fit insay lɔk. dis atachmεnt na in de tεl di bεlε se, "Okay, naw mek asid."
we yu tek wan H2 blכka, di dכg de go εn tay pan dεn H2 rεsεpכta dεm (di lכk dεm) εn "blכk" dεm. da we de, di H2 (di ki dεm) nכ de gεt chans fכ kam εn biεn di rεsεpכta dεm. we di signal fכ mek asid stכp, di bכdi de prodyuz sכm asid.
Dis nɔ de ambɔg yu dijestiv prɔses. I jɔs de kɔntrol di bɔku ɛkstra asid we de mek pɔsin fil pen ɛn nɔ fil fayn.
Us H2 blɔk mɛrɛsin dɛn de?
Difrɛn kayn H2 blɔk dɛn de. Sɔm dɛn kin bay ɔva-di-kɔnta (OTC), ɛn ɔda wan dɛn nid fɔ gɛt prɛskrishɔn frɔm dɔktɔ.
| Nem fɔ di drɔg | Wan brand we pipul dɛn kin si | Aw fɔ gɛt am |
|---|---|---|
| Simɛtidin we dɛn kɔl | Tagamet® we gɛt di taytul | Ova-di-kɔnta ɛn prɛskrishɔn (OTC & Rx) . |
| Famotidin we dɛn kɔl famotidin | Pepcid® we dɛn kɔl | Ova-di-kɔnta ɛn prɛskrishɔn (OTC & Rx) . |
| Nizatidin we dɛn kɔl Nizatidine | Axid® we dɛn kɔl | Na pan dɔktɔ in prɛskrishɔn nɔmɔ (Rx nɔmɔ) |
Speshal Notis: Yu kin mɛmba di H2 blɔk Ranitidine (Zantac®) we bin rili pɔpul trade. Bɔt insay Epril 2020, ɛjɛnshi dɛm lɛk FDA (US Food and Drug Administration) bin tɛl di wan dɛn we de mek am fɔ pul dis mɛrɛsin na di makit. Di rizin na bikɔs di tɛst dɛn sho se as tɛm de go ɛn we dɛn kip am na ay tɛmpracha, di lɛvɛl fɔ wan kemikal we dɛn kɔl nitrosodimethylamine, ɔ NDMA, we na sɔntin we kin mek pɔsin gɛt kansa, kin go ɔp to di lɛvɛl we nɔ sef.
Aw ɛn ustɛm dɛn fɔ yuz dis mɛrɛsin?
Yu kin tek H2 blɔk wit yu mɔt as pils ɔ kapsul. Paoda dɛn de bak we dɛn kin sɔlv insay wata fɔ pipul dɛn we nɔ kin izi fɔ swɛla pils. Dɛn kin gi dɛn bak insay dɛn bɛlɛ (IV) to pasɛnt dɛn we de na ɔspitul ɛn we nɔ ebul fɔ tek mɛrɛsin we dɛn kin tek bay mɔt.
Di bɛst tɛm fɔ tek di mɛrɛsin
- Fɔ mek yu nɔ fil fayn wan wan tɛm:If yu no se fɔ it tin dɛn we gɛt spays ɔ fat kin mek yu gɛt prɔblɛm, tek wan H2 blɔk 30 to 60 minit bifo yu it da it de. Dat de gi am tɛm fɔ wok. I nɔ bad fɔ tek am afta di prɔblɛm dɔn bigin, bɔt i kin tek te to wan awa fɔ mek di sik nɔ kam.
- Fɔ wan kɔndishɔn lɛk fɔ wɛl wund: Yu dɔktɔ kin se yu fɔ tek am wan tɛm insay di de bifo yu go slip, ɔ wan tɛm na mɔnin ɛn wan tɛm na nɛt, i go dipen pan wetin yu dɔktɔ tɛl yu.
Di tin we impɔtant pas ɔl na dat if yu nid fɔ yuz dɛn mɛrɛsin ya fɔ pas tu wiks wan tɛm, yu fɔ rili go to yu dɔktɔ. I nɔ fayn fɔ kɔntinyu fɔ yuz dɛn tin ya we yu nɔ no di rayt tin we mek yu gɛt di sik.
Wetin na di difrɛns bitwin H2 Blɔka, Antasid ɛn PPI?
Bɔrku pipul kin kɔnfyus bɔt dɛn tri kayn mɛrɛsin ya wae dɛn kin yuse fɔ gɛt at pwɛl. Lɛ wi tek tɛm luk di men tin dɛn we difrɛn bitwin dɛn.
| Di kayn drɔg we dɛn kin yuz | Taym we dɛn tek fɔ ɔpreshɔn | Di tɛm we di ɛfɛkt go tek | Di chans we fit pas ɔl |
|---|---|---|---|
| Di tin dɛn we de mek pɔsin nɔ gɛt asid (e.g. Dijɛn, Gɛlusil) | Rili kwik (fɔ sɔm minit) . | Rili shɔt (1-2 awa) . | We dɛn nid fɔ gɛt ɛp kwik kwik wan. |
| H2 Blɔka dɛn | Na lɛk wan awa so | Na lɛk 4-10 awa so | Fɔ mek yu nɔ gɛt at bɔn wan wan tɛm ɔ bifo yu it. |
| PPI dɛn (Protɔn Pɔmp Inhibitɔ dɛn) . | 1-4 dez fɔ ful ɛfɛkt | Lɔng tɛm (24 awa+) . | Fɔ kɔndishɔn dɛn lɛk kronik gastritis ɛn GERD. |
Ɛni bad bad tin dɛn de we kin apin to am?
H2 blok dεm na jεnarali rili sef mεdikeshכn wit fכ sayd ifekt . Ivin if di sayd ɛfɛkt dɛn kin apin, bɔku tɛm dɛn kin smɔl.
- Bɛlɛ de pen
- Mɔsul dɛn kin pen
- Banbɛlɛ
- Rɔnbɛlɛ
- Dray mɔt
- Taya
- Ed de at
Na smɔl tɛm nɔmɔ, pipul dɛn we de na grup dɛn we gɛt ay risk (espɛshali di wan dɛn we dɔn pas 50 ia, di wan dɛn we gɛt prɔblɛm wit dɛn kidni ɔ liva) kin gɛt sɔm sayn dɛn we gɛt fɔ du wit di nervɔs sistɛm, lɛk we dɛn nɔ kin mɛmba ɔ i nɔ kin izi fɔ tɔk. Bɔt dis nɔ kin apin so ɔltɛm . Dɛn sik ya kin dɔn insay sɔm dez afta dɛn dɔn stɔp di mɛrɛsin.
Intarakshɔn wit ɔda drɔgs
Sɔm H2 blɔk kin afɛkt di we aw ɔda mɛrɛsin dɛn we yu de tek de wok. fכ egzampl, di H2 blכk simetidin kin ridyus di effektiv we sכm antidipreshכn (SSRI) dεm εn di blכd tina wכfarin (`(warfarin)`) de wok.
So, bifo yu bigin fɔ yuz nyu H2 blɔk, i rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu dɔn ɔlrɛdi de tek.
Dɛn tin ya fayn fɔ mama dɛn we gɛt bɛlɛ ɛn we de gi pikin dɛn bɛlɛ?
mכr risεch stil nid fכ de fכ di sef fכ yuz H2 blכk dεm we uman bεlε, bכt dεn no se dεn dכg dεm ya de pas to di pikin tru in mama in milk.
So, if yu gɛt bɛlɛ, yu plan fɔ gɛt bɛlɛ, ɔ yu na mama we de gi pikin in bɛlɛ, mek shɔ se yu tɔk to yu dɔktɔ bifo yu tek ɛni wan pan dɛn mɛrɛsin ya.
Mɛsej we dɛn kin kɛr go na os
- H2 blɔk na wan kayn mɛrɛsin we de ridyus di bɛlɛ asid. Dɛn fayn fɔ gi shɔt tɛm rilif frɔm at-bɔn ɛn chɛst pen wan wan tɛm.
- Pan ɔl we dɛn tin ya kin wok fast pas PPI, dɛn nɔ fayn fɔ yuz fɔ lɔng tɛm, ɛvride.
- If yu nid fɔ yuz H2 blɔk fɔ pas tu wiks wan tɛm, i kin min se yu gɛt ɔda ɔndalayn prɔblɛm. Fɔ tru, yu go si dɔktɔ.
- Tɛl yu dɔktɔ bɔt ɛni ɔda mɛrɛsin we yu de tek (ivin vaytamɛn).
- If yu gɛt bɛlɛ ɔ yu de gi pikin in bɛlɛ, nɔ yuz dɛn mɛrɛsin ya if yu nɔ gɛt dɔktɔ advays.
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