We dɛn dɔn no se yu ɔ pɔsin we yu sabi gɛt kansa ɛn yu dɔktɔ tɛl yu fɔ bigin tek wan mɛrɛsin we dɛn kɔl Sorafenib, i nɔmal fɔ mek yu fred smɔl ɛn want fɔ no mɔ. Us kayn mɛrɛsin dis? Aw i kin wok? Ɛni bad bad tin dɛn de we kin apin to am? Yu go mɔs gɛt bɔku kwɛstyɔn dɛn lɛk dɛn wan ya na yu maynd. So tide, lɛ wi lan ɔltin bɔt dis mɛrɛsin we dɛn kɔl Sorafenib, lɛk se yu de tɔk to yu padi.
Fɔ tɔk am simpul wan, wetin na Sorafenib?
Sorafenib nɔ tan lɛk di kemotɛrapi drɔgs we wi kin no. Na wan spɛshal kayn mɛrɛsin we dɛn kɔl targeted therapy . Tink bɔt am lɛk se wan rɛgyula kemotɛrapi drɔg tan lɛk fɔ bɔm wan ol siti, ɛn i kin pwɛl gud sɛl dɛn bak. Bɔt targeted therapy tan lɛk fɔ fɛn ɛksaktɔli usay di ɛnimi de ɛn atak na da ples de nɔmɔ.
Sorafenib de wok bay we i de blok di aktiviti fכ spεshal protin dεm we de εp di kεnsar sεl dεm fכ gro εn fכm bכdi vεsul dεm. Dis kin mek di kansa sɛl dɛn nɔ gro ɛn skata.
Dɛn kin yuz am mɔ fɔ mɛn liva kansa , kidni kansa , ɛn tayroyd kansa . Insay Sri Lanka, yu kin fɛn dis mɛrɛsin ɔnda di brand nem Nexavar .
Tin dɛm wae yu fɔ tɛl yu dɔktɔ bifo yu bigin dis mɛrɛsin
Sorafenib na wan mɛrɛsin we rili strɔng, so i rili impɔtant fɔ gi yu dɔktɔ kɔmplit diskripshɔn bɔt yu wɛlbɔdi kɔndishɔn. Ɛspɛshali if yu gɛt ɛni wan pan di kɔndishɔn dɛn we de dɔŋ ya, mek shɔ se yu tɛl dɛn bɔt am.
| Yu wɛlbɔdi kɔndishɔn | Wetin mek i impɔtant fɔ tɛl di dɔktɔ? |
|---|---|
| Di prɔblɛm dɛn we kin apin we pɔsin de blɔd | Dis mɛrɛsin kin mek yu gɛt mɔ blɔd. |
| At sik ɔ at we nɔ de bit ɔltɛm | Di drɔg kin afɛkt di we aw di at de wok ɛn di at rit. |
| Di ay blɔd prɛshɔn | Sorafenib kin mek yu blɔd prɛshɔn go ɔp mɔ, so i impɔtant fɔ kɔntrol am. |
| Ɔda liva sik dɛn | If yu dɔn gɛt liva prɔblɛm, di tin we di mɛrɛsin kin du kin chenj. |
| If yu jɔs dɔn du ɔpreshɔn ɔ yu de kam fɔ du ɔpreshɔn | Dis mɛrɛsin kin mek di wund nɔ wɛl. |
| If yu gɛt bɛlɛ ɔ yu de tray fɔ gɛt bɛlɛ | Dis rili impɔtant. Dis mɛrɛsin kin ambɔg di pikin we de na in bɛlɛ bad bad wan. |
| If dɛn de gi di pikin in mama in bɛlɛ | Di mɛrɛsin kin pas tru di mama in milk ɛn i kin ambɔg di pikin. |
| Alɛji to ɔda mɛrɛsin, it ɔ tin dɛn | I impɔtant fɔ no if yu gɛt alɛji fɔ Sorafenib ɔ ɛni wan pan di tin dɛn we de insay am. |
Wetin na di kɔrɛkt we fɔ tek di mɛrɛsin?
Dis pil fɔ tek yu mɔt wit wan glas wata.
- Nɔ brok, krɔs, ɔ chew di tablɛt. Swɛla am ɔl.
- Di tin we impɔtant pas ɔl: Dɛn fɔ tek dis we yu ɛmti bɛlɛ . Dat min se, at le wan awa bifo yu it ɔ tu awa afta yu it. If yu tek am wit it, i go mek di mɛrɛsin nɔ go insay di bɔdi.
- Tek yu mɛrɛsin jɔs lɛk aw yu dɔktɔ tɛl yu, di tɛm we dɛn tɛl yu. Nɔ stɔp fɔ tek am fɔ yusɛf. Nɔ stɔp di mɛrɛsin if yu nɔ gɛt dɔktɔ advays.
Atɛnshɔn: If yu tink se yu dɔn tek bɔku mɛrɛsin, nɔ west tɛm ɛn go na di Imejɛnsi Tritmɛnt Yunit (ETU) we de nia yu wantɛm wantɛm . Ɔ kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital .
Wetin fɔ du if yu mis wan doz fɔ mɛrɛsin?
If yu mis wan doz, tek am jɔs afta yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek tu dos wan tɛm.
Prɔblɛm kin de wit ɔda mɛrɛsin dɛn? (Drug Intarakshɔn) .
Yes, Sorafenib na wan mɛrɛsin wae kin intarakt wit ɔda mɛrɛsin dɛm. So, yu fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, lɛk di wan dɛn we yu dɔktɔ gi yu, di wan dɛn we yu bay na di famasi, tradishɔnal mɛrɛsin dɛn, vaytamɛn dɛn, ɛn ɛbul sɔpɔtmɛnt dɛn.
Na mɔtalman, nɔ tek Sorafenib wit dɛn mɛrɛsin ya:
- Cisapride we dɛn kɔl Cisapride
- Dronedarone we gɛt di sik
- Pimozayd we dɛn kɔl Pimozide
- Tioridazin we dɛn kɔl Tioridazin
Dɔn bak, i impɔtant fɔ tɛl yu dɔktɔ if yu de tek dɛn mɛrɛsin ya, bikɔs dɛn kin miks wit Sorafenib.
- Antikonvulsant mεdikeshכn dεm (e.g. Carbamazepine, Phenobarbital, Phenytoin) .
- Di kayn antibayɔtik dɛn (e.g. Rifampin, Rifabutin) .
- Dexamethasone (wan kayn stɛroyd) .
- Digoxin (na mɛrɛsin fɔ at sik) .
- St. John’s Wort we dɛn mek wit ɛbul prodak
- Ɔda mɛrɛsin dɛn we de afɛkt di at rit (we de afɛkt di QT intaval) .
- Vinblastine (ɔda mɛrɛsin we de mek pɔsin nɔ gɛt kansa) .
Dis list nɔ kɔmplit, so tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.
Tin dɛn we yu fɔ mɛmba we yu de tek mɛrɛsin
Bɛlɛ ɛn bɔn pikin
Dis na di tin we impɔtant pas ɔl we wi fɔ tek tɛm wit.
- Uman: Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin. I nɔ fayn fɔ gɛt bɛlɛ fɔ te 6 mɔnt afta yu dɔn stɔp di mɛrɛsin. Tɔk to yu dɔktɔ bɔt di we we go mek yu nɔ bɔn pikin we go wok fayn pas ɔl.
- Man: If yu de tek dis mɛrɛsin, yu fɔ avɔyd fɔ bɔn pikin we yu de tek di mɛrɛsin ɛn fɔ 3 mɔnt afta yu dɔn stɔp. I impɔtant fɔ mek yu ɛn yu patna yuz wan we we rili ɛp fɔ mek yu nɔ bɔn pikin.
Bikɔs dis mɛrɛsin kin mek di pikin we nɔ bɔn yet gɛt siriɔs ɛn fɔ ɔltɛm, yu fɔ avɔyd fɔ gi pikin in bɛlɛ atɔl we yu de tek dis mɛrɛsin.
Ɔpreshɔn ɛn wund wɛl
If yu go gɛt ɛni ɔpreshɔn ɔ dɛnt wok, tɛl yu dɔktɔ ɔ dɛntist bifo tɛm se yu de tek Sorafenib. Bikɔs dis mɛrɛsin de slo di wɛl bɔdi, dɛn kin bigin am 2 wik afta dɛn dɔn du big ɔpreshɔn.
Blɔd ɛn infɛkshɔn
Dis mɛrɛsin kin mek i izi fɔ mek pɔsin brus ɛn blɔd, ɛn i kin mek di bɔdi nɔ ebul fɔ fɛt infɛkshɔn bak.
- If yu notis ɛni blɔd we nɔ kɔmɔn (e.g. frɔm di gam, nos), tɛl yu dɔktɔ.
- Tek tɛm we yu de brus yu tit ɛn yuz tutpik.
- If yu gɛt sɔm sayn dɛm lɛk fiva, kol, ɔr trot we de at, nɔr de mɛn yusɛf ɛn tɔk to yu dɔktɔ. Nɔ go na say dɛn we sik pipul dɛn kin gɛda.
Wetin na di bad tin dɛn we kin apin to pɔsin?
Lɛk ɛni mɛrɛsin, Sorafenib kin gɛt sayd ɛfɛkt. Nɔto ɔlman kin gɛt dɛn, bɔt i impɔtant fɔ no bɔt dɛn.
| Tayp fɔ di sayd ɛfɛkt | Sayn dɛn |
|---|---|
| Siriɔs sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip, tong, i nɔ izi fɔ blo. |
| Sayn dɛn we de sho se pɔsin de blɔd | Blak, tar stɔl dɛn; blɔd we de vɔmit ɔ stɔl we tan lɛk kɔfi grɔn. |
| Di sayn dɛn we de sho se pɔsin gɛt at atak | Chest pen ɔ tayt, at bit fast ɔ i nɔ de bit ɔltɛm. |
| Liva prɔblɛm dɛn | di yay ɔ di skin we de yɔlɔ, di urine we dak, pen na di ɔp rayt say na di bɛlɛ. |
| Di sik dɛn we kin mek pɔsin gɛt siriɔs sik na di skin | Rɛd, pen, blista, ɔ sos na di an ɛn di fut in fut. Sɔl dɛn we de insay di mɔt. |
| Ɔda bad bad sayn dɛn | Bɛlɛ pen bad bad wan, diziz, fil fɔ fil fɔdɔm. |
| Sayd ɛfɛkt dɛn we nɔ kin siriɔs, bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| Dijestiv sistɛm | Dayarɛa, we pɔsin nɔ want fɔ it igen. |
| Di bɔdi kin chenj | I de lɔs, taya, we yu de lɔs. |
Mɛsej we dɛn kin kɛr go na os
- Sorafenib na wan tεrapi we dεn de tכk bכt we de stכp di gכt fכ di kεnsar sεl dεm.
- Ɔltɛm tek dis mɛrɛsin wit ɛmti bɛlɛ, we min wan awa bifo ɔ tu awa afta yu it.
- Mek shɔ se yu tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn we yu de tek.
- Go to dɔktɔ kwik kwik wan if yu gɛt siriɔs sayd ɛfɛkt lɛk we yu de fil pen na yu chɛst, we yu gɛt siriɔs riakshɔn na yu skin, ɔ blɔd we nɔ kɔmɔn.
- Nɔ gɛt bɛlɛ ɔltogɛda we yu de tek dis mɛrɛsin ɛn fɔ sɔm mɔnt afta yu dɔn stɔp am. Dis kin apin to uman ɛn man.
- Nɔ ɛva stɔp fɔ tek yu mɛrɛsin ɔ chenj di doz if yu dɔktɔ nɔ advays yu. Tɔk to dɛn bɔt ɛni prɔblɛm.
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