Imajin, wan bad bad pen na yu chɛst wantɛm wantɛm... yu de swet, ɛn i nɔ izi fɔ blo. Aw yu kin fil fɔ fred we yu kam fɔ no se yu gɛt at atak? Tide wi de tɔk bɔt wan spɛshal injɛkshɔn we kin sev di pɔsin in layf pan dis kayn imejensi, impɔtant tɛm na layf. Dis na wan mɛrɛsin we dɛn kɔl Tenecteplase.
Fɔ tɔk am simpul wan, wetin na Tenecteplase?
Tenecteplase, ɔ TNK-tPA, na wan mɛrɛsin we rili pawaful we de sɔlv di blɔd we de klɔt. Dɔktɔ dɛn kin kɔl am bak "clot-buster."
Naw, lɛ wi si aw at atak kin apin. We blɔd klɔt wantɛm wantɛm na blɔd vesel (koronary artery) we de gi blɔd to wi at, di blɔd we de go na di at mɔsul kin stɔp ɛn da pat de bigin fɔ day. Na da tɛm de dɛn kin yuz dis mɛrɛsin. di tenecteplase injεkshכn de wok bay we i de sכlv di bכdi we dεn blכk kwik kwik wan εn i de mek di bכdi fכ fכlכ bak na di at. Dis tan lɛk we yu pul big tin we dɔn blok na rod ɛn alaw motoka dɛn fɔ pas.
Tin dɛm fɔ tɛl di dɔktɔ bifo yu gi dis mɛrɛsin
Bikɔs dis na mɛrɛsin we rili strɔng, i kin denja fɔ yuz am wit sɔm tin dɛn we de apin na yu bɔdi. So, bifo yu tek dis mɛrɛsin, yu fɔ rili tɛl yu dɔktɔ if yu gɛt ɛni wan pan dɛn tin ya:
| Di sityueshɔn ɔ di chans we yu go gɛt | Wetin mek wi fɔ tɛl pipul dɛn bɔt am? |
|---|---|
| Aneurysm (we di wɔl na di blɔd vesel we de na di bren ɔ ɔdasay wik) . | Di risk fɔ mek blɔd kɔmɔt na di bɔdi rili bɔku. |
| Blɔd disɔda, prɔblɛm wit blɔd we de klɔt | Di mɛrɛsin kin mek yu blɔd we yu nɔ ebul fɔ kɔntrol. |
| Dayabitik Rɛtinopati (blɔd we de kɔmɔt na di yay bikɔs ɔf dayabitis) . | Blɔd we de kɔmɔt na di yay kin bɔku. |
| Wan infεkshכn na di at valv dεm (Endocarditis) . | Risk de fɔ mek blɔd kɔmɔt na di pat dɛn we gɛt di sik. |
| Wan ed injuri we i jɔs dɔn gɛt, in bren sik, ɔ tumor | Di risk fɔ mek blɔd kɔmɔt na di bren rili bɔku. |
| Di ay blɔd prɛshɔn we dɛn nɔ kin kɔntrol | Blɔd prɛshɔn kin mek di vein dɛn bɔs ɛn blɔd. |
| Ɔpreshɔn we dɛn jɔs du, bɔn pikin, bayɔpsi, ɔ siriɔs injuri | Blɔd kin bigin bak frɔm di say dɛn we dɛn de du ɔpreshɔn. |
| Stroke we i jɔs gɛt | Wan ɔda blɔd we kin kɔmɔt na di bren kin apin. |
| Ɔlsa na bɛlɛ ɔ ɔlsa we de blɔd | Blɔd we de kɔmɔt na di bɛlɛ ɔ insay di bɔdi kin bɔku. |
| Fɔ gɛt bɛlɛ, fɔ tray fɔ gɛt bɛlɛ, ɔ fɔ gi pikin in bɛlɛ | Di dɔktɔ fɔ no bɔt di prɔblɛm dɛn we kin apin to di mama ɛn di pikin. |
| Alɛji to ɛni ɔda mɛrɛsin ɔ it | Fɔ mek yu nɔ gɛt alɛji. |
Aw yu kin yuz dis mɛrɛsin?
Dis nɔto mɛrɛsin we yu kin pik na famasi ɛn kɛr go na os. Tenecteplase na ɔspitul ɔ klinik nɔmɔ dɛn kin gɛt., na vaysin we dɔktɔ ɔ pɔsin we dɔn tren fɔ du wɛlbɔdi biznɛs kin gi. Dat min se na imejensi nɔmɔ dɛn kin yuz am, fɔ pɔsin we de na ɔspitul.
Dis na injεkshכn insay wan vein, so di ifekt dεm kin rili kwik.
If yu gɛt smɔl pikin ɛn yu nid fɔ gi dɛn dis mɛrɛsin, yu nid spɛshal kia. Yu fɔ tɔk to yu dɔktɔ bɔt dis ɛn gɛt advays.
Bikɔs dɛn kin gi dis mɛrɛsin di kɔrɛkt doz na di ɔspitul, no prɔblɛm nɔ de fɔ ‘ɔvados’. Bɔt if yu tink se yu gɛt ɛni pɔyzin we gɛt fɔ du wit drɔgs, go wantɛm wantɛm na di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital , ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) we de nia yu.
Ɔda mɛrɛsin dɛm wae de miks wit dis mɛrɛsin (Drug Interactions) .
Ɔda mɛrɛsin dɛn we yu de tek kin miks wit dis mɛrɛsin, so i rili impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.
- Nɔ tek dis mɛrɛsin wit: Dɛn nɔ fɔ yuz mɛrɛsin lɛk Aminocaproic acid, Aprotinin, Tranexamic acid wit dis mɛrɛsin.
- Tek tɛm mɔ if yu de tek dis mɛrɛsin:
- Antiplatelet dכg dεm - fכ egzampl `klopidogrεl`, `tiklopidin`
- Aspirin ɛn ɔda kayn drɔgs dɛn
- Blɔd tin dɛm - fɔ ɛgzampul `warfarin`, `heparin`, `enoxaparin`
- Pen kil ɛn anti-inflammatory drugs (NSAID) - fɔ ɛgzampul `ibuprofen` ɔ `naproxen`
Dis list nɔ kɔmplit. Tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek, lɛk vaytamɛn dɛn, ɛbul mɛrɛsin dɛn, ɛn sɔpɔtmɛnt dɛn. Dɔn bak, tɛl yu dɔktɔ if yu de smok ɔ drink rɔm.
Tin dɛn we yu fɔ tek tɛm wit afta yu dɔn tek di mɛrɛsin
Afta dɛn dɔn gi yu dis mɛrɛsin, di mɛdikal wokman dɛn go wach yu gud gud wan.
Di men sayd ɛfɛkt we dis mɛrɛsin kin gɛt na we i kin mek i gɛt mɔ blɔd . Dis ifɛkt kin las fɔ sɔm dez.
So, yu nid fɔ tek tɛm bad bad wan insay dis tɛm.
- We yu de brus ɛn yuz flos, du am sloslo fɔ mek yu nɔ pwɛl yu gɔm.
- Tray yu bɛst fɔ mek yu nɔ wund yusɛf ɛnisay na yu bɔdi.
- If yu dɔktɔ tɛl yu fɔ rɛst na bed, fala am strikt wan. Dis kin ɛp fɔ mek yu nɔ gɛt blɔd we kin apin bikɔs yu de muv we yu nɔ nid fɔ muv.
- Nɔ tek pen kil lɛk aspirin ɛn ibuprofen dɛn tɛm ya we yu nɔ gɛt dɔktɔ advays.
Wetin na di bad tin dɛn we kin apin to pɔsin?
Lɛk ɛni mɛrɛsin, dis wan kin gɛt sayd ɛfɛkt. Sɔm pan dɛn kin siriɔs ɛn dɛn fɔ ripɔt dɛn wantɛm wantɛm.
| Nature of di sayd ɛfɛkt | Sayn dɛn |
|---|---|
| Notis yu dɔktɔ ɔ di nɔs wokman dɛn wantɛm wantɛm. | |
| Alɛji Riakshɔn dɛn | Skin rash, it, swel na yu fes, lip, ɔ tong, i nɔ izi fɔ blo. |
| Sayn dɛn we de sho se pɔsin de blɔd | Blak ɔ blɔd stɔl; urine we gɛt rɛd ɔ dak-brawn; fɔ vɔmit tin dɛn we tan lɛk kɔfi grɔn; rɛd spat dɛn na di skin; blɔd we nɔ kɔmɔn frɔm di yay, di gɔm, ɔ di nos. |
| Sayn dɛn we de sho se pɔsin gɛt strok | Di we aw pɔsin de si tin kin chenj; kɔnfyus; i nɔ kin izi fɔ tɔk ɔ ɔndastand; ed we kin at bad bad wan; di fes, an, ɔ leg kin swɛt ɔ wik wantɛm wantɛm; i nɔ izi fɔ waka, diziz. |
| Di chenj dɛn we de apin na di at rit | At rit we nɔ kin slo ɔ fast. |
| If i kɔntinyu ɔ i de mɔna yu, tɛl yu dɔktɔ. | |
| Diziz we pɔsin kin gɛt | Fɔ fil lɛk se yu gɛt layt. |
| Fiva | Di bɔdi wam. |
| Nɔs, Vɔmit | Bɛlɛ de at ɛn vɔmit. |
Dis list nɔ de inklud ɔl di sayd ɛfɛkt dɛn we pɔsin kin gɛt. If yu gɛt ɛni kwɛstyɔn bɔt dis, nɔ fred fɔ aks yu dɔktɔ.
Mɛsej we dɛn kin kɛr go na os
- Tenecteplase na pawaful mɛrɛsin we de sev layf, we dɛn kin gi fɔ sɔlv di blɔd we kin klɔt we pɔsin gɛt at atak. Na ɔspitul nɔmɔ dɛn kin gi am.
- Di men ɛn siriɔs risk fɔ dis mɛrɛsin na fɔ blɔd. So, tek tɛm bad bad wan fɔ mek yu nɔ wund fɔ sɔm dez afta yu dɔn tek di mɛrɛsin.
- Mek shɔ se yu tɛl yu dɔktɔ bɔt yu ɔda mɛrɛsin dɛn (especially we yu de blɔd, we yu jɔs du ɔpreshɔn, ay blɔd prɛshɔn) ɛn ɔl di mɛrɛsin dɛn we yu de tek.
- If yu notis ɛni blɔd we nɔ kɔmɔn, sayn dɛn fɔ alɛji (lɛk we yu fes swel), ɔ sayn dɛn fɔ strok (lɛk we yu nɔ gɛt swɛla wantɛm wantɛm), tɛl di dɔktɔ dɛn wantɛm wantɛm.
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