Sɔntɛnde yu kin bigin fɔ it wantɛm wantɛm, yu skin kin tɔn rɛd ɛn brok ɔt wit rash? Ɔ yu kin fil sik to yu bɛlɛ wantɛm wantɛm ɛn fil lɛk fɔ vɔmit? Sɔntɛnde, dɛn tin ya kin apin afta yu dɔn yuz wan patikyula sɛnt, ɔ afta yu dɔn it wan patikyula it, ɛn sɔntɛnde dɛn kin apin fɔ natin. If yu nɔr ebul fɔ fɛn rizin fɔ dis, ɛn yu gɛt difrɛn sayn dɛm na difrɛn tɛm, e kin bi se na sɔntin we pas jɔs alɛji. Tide wi de tɔk bɔt wan pan dɛn kayn tin ya, we na Mast Cell Activation Syndrome (MCAS).
Wetin na di Mast Sεl Aktivεshכn Sεndrכm (MCAS)?
Fɔ tɔk am simpul wan, MCAS na kɔndishɔn we wan kayn sɛl na wi bɔdi we dɛn kɔl ‘mast sɛl’ de bi we nɔ nid ɛn we de wok pasmak, we de pul bɔku bɔku kεmikכl dεm we de insay di bכdi.
Naw lɛ wi luk wetin na dɛn mast sɛl ya. Tink bɔt dɛn sɛl dɛn ya as di wan dɛn we de gayd di bɔdi. Dɛn na pat pan wi imyun sistɛm. Dɛn men wok na fɔ fɛt di infɛkshɔn. Bɔt na dɛn sɛl ya kin mek pɔsin gɛt alɛji bak. כltεm, we sכmtin we de ambɔg wi, fכ egzampl, wan alerjen go insay di bכdi, dεn mast sεl dεm ya de aktibכt εn de rilis kεmikכl dεm we dεn kכl ‘mεdiate’. Dɛn kemikal ya na dɛn kin mek wi bɔdi gɛt alɛji. Insay pɔsin we gɛt wɛlbɔdi, dis prɔses na fɔ protɛkt wi.
Bɔt, pan pɔsin we gɛt MCAS, dɛn mast sɛl ya kin rili sɛnsitiv . Dɛn kin gladi pasmak fɔ ivin di smɔl tin ɛn dɛn kin pul bɔku bɔku kemikal dɛn wan tɛm. I tan lɛk se yu kam wit wan ol ami fɔ kech wan smɔl tifman. Dɛn kemikal ya we wi nɔ want na dɛn kin mek bɔku pan di sik dɛn we nɔ kɔmɔn ɛn we kin mɔna wi we wi bin dɔn tɔk bɔt.
difrεn tin dεm de we kin כltεm trigεr dεn mast sεl dεm ya:
- Infεkshכn dεm
- Sɔm mɛrɛsin dɛn
- Pɔyzin we insɛkt dɛn bit
- Smɔl sɛnt dɛn
- Strɛs
- Ɛksasayz
- Sɔm it dɛn
- Di tɛmpracha kin chenj wantɛm wantɛm
MCAS εn Mastocytosis na tu difrεnt tin dεm?
Yɛs, nɔ kɔnfyus di tu. Pan ɔl we dɛn tu tin ya gɛt fɔ du wit mast sɛl dɛn, dɛn difrɛn.
| Mɛdikal kɔndishɔn | Fɔ tɔk am simpul wan, wetin kin apin? |
|---|---|
| Mastosaytɔsis we de mek pɔsin gɛt sik | wetin kin apin pan dis na dat di bכdi de prodyuz wan abnכmal hכy nכmba fכ mast sεl dεm. I tan lɛk se yu de tek tumɔs sikyɔriti gad dɛn. Dɛn sɛl dɛn ya we pasmak kin gɛda na di ɔgan dɛn lɛk di skin, di liva, ɛn di insay. Dis na tin we nɔ kin apin so ɔltɛm. |
| MCAS (Mast Sεl Aktivεshכn Sεndrכm) . | wetin kin apin insay dis kes na dat di nכmba fכ di mast sεl dεm na di bכdi nכmal, bכt di sεl dεm we de de kin bi haypa aktif. Di gad dɛn we de de kin gladi fɔ di smɔl tin ɛn dɛn kin pul kemikal dɛn. |
Wetin na di tin dɛn we kin mek pɔsin gɛt MCAS?
Dɛn kin sheb MCAS to tri men kategori bay di kɔz.
1. Praymari MCAS: dis kin kכz fכ prכblεm wit di mast sεl dεm sεf. כltεm, wan mכtεshכn na di jin ``(KIT)`` de mek dεn sεl dεm ya de bihayv abnכmal. Mastocytosis na di men kכndyushכn na dis tכp.
2. sεkכnd MCAS: dis kin apin we di mast sεl dεm de stimulate bay כda εksternal kכz. Fɔ ɛgzampul, dis kin bi bikɔs ɔf wan bad bad alɛji, infɛkshɔn we nɔ de dɔn, ɔ ɔda mɛrɛsin.
3. Idiopathic MCAS: "Idiopathic" min "dεn kin fכn nכ kכz." Di majoriti of MCAS pasɛnt dɛn gɛt dis kayn. dis min se no patikyula rizin nכ de we mek dεn mast sεl dεm ya de bihayv abnכmal. Di sayn dɛm kin apia fɔ nyu tin dɛm ɛnitɛm.
Wetin na di poshubul simptom dɛm fɔ MCAS?
Wan pan di big chalenj dɛm wit MCAS na dat di simptom dɛm so difrɛn ɛn kin afɛkt bɔku bɔdi sistɛm dɛn wan tɛm.
| Kategori fɔ di simptom dɛn | Di sayn dɛm we dɛn kin si bɔku tɛm |
|---|---|
| Skin ɛn di jenɛral kwaliti dɛn | Flush, it, rash/hayv, swel, swet pasmak, taya fɔ lɔng tɛm, bɔdi pen. |
| Dijestiv sistɛm | Bɛlɛ pen, nɔs, vɔmit, dayarɛa, kɔnstipɛshɔn. |
| Nɛvɔ sistɛm (Nyurolɔjik) . | Ed pen, mɛmori ɛn atɛnshɔn prɔblɛm (Bren fɔg), diziz, fɔdɔm, wɔri, pwɛl hat, nɔr de slip. |
| At ɛn di we aw yu de blo | Hat de bit kwik ɔ we nɔ de bit ɔltɛm (palpitations), i nɔ izi fɔ blo, di chɛst tayt. |
Speshal atɛnshɔn: Anafylaktik Shɔk
Anafylaksis na di sik we denja pas ɔl ɛn we de mek pɔsin in layf de pan denja we kin apin to pipul dɛn we gɛt MCAS. Dis na wan sik wae nid fɔ gɛt mɛrɛsin kwik kwik wan.
Di sayn dɛm fɔ anafilaksis:
- I nɔ izi fɔ blo, fil lɛk se yu trot dɔn kɔnstrikt
- Di lip, tɔng, ɔ fes we de swel
- At rit kin rili fast.
- Di blɔd prɛshɔn we de go dɔŋ wantɛm wantɛm
- Diziz bad bad wan ɛn fɔdɔm
- Vɔmit ɛn dayarɛa
- Rɛd ɛn rash ɔlsay na di bɔdi wantɛm wantɛm
If yu gɛt wan ɔr mɔr pan dɛn sik ya, nɔr de delay. Kɔl ambulans wantɛm wantɛm ɔ go na di Imejɛnsi Dipatmɛnt (ETU) na di ɔspitul we de nia yu.
Aw a go no if a gɛt MCAS?
Fɔ no MCAS kin kɔmplikt smɔl bikɔs di sayn dɛm kin difrɛn. Bɔku tɛm, yu dɔktɔ go luk fɔ tri tin dɛn mɔ.
1. di simptom dεm: di prεsεns fכ rikar, krεse lεk alerjik simptom dεm na tu כ mכr bכdi sistεm dεm (e.g., skin εn intestines).
.
3. Rispɔns to tritmɛnt: Di simptom dɛn kin go dɔŋ we dɛn gi am drɔgs we de blok mast sɛl aktiviti, lɛk antihistamin.
If dɛn mit ɔl dɛn tri tin ya, di dɔktɔ kin sɔprayz se MCAS. Sɔntɛnde MCAS kin kam wit wan kɔndishɔn we dɛn kɔl ``(POTS)`` - Postural Orthostatic Tachycardia Syndrome. Dis na we di at rit de go ɔp abnɔmal wan we yu tinap.
Aw dɛn kin trit am?
No mɛrɛsin nɔ de fɔ MCAS yet. Bɔt dɛn kin kɔntrol di sik dɛn fayn fayn wan ɛn dɛn kin gɛt nɔmal layf. Di tritmɛnt gɛt tu men gol dɛn.
1. Fɔ Avɔyd di tin dɛn we kin mek yu gɛt dis sik: Di tin we impɔtant pas ɔl na fɔ no wetin kin mek yu gɛt di sik ɛn avɔyd dɛn.
2. Kɔntrol di sayn dɛm wit mɛrɛsin: Di dɔktɔ go gi yu difrɛn mɛrɛsin dɛm.
- H1 ɛn H2 antihistamin: Drɔg dɛn lɛk Sɛtirizin, Loratadin, Famotidin.
- Mast Cell Stabilizers: Na drɔgs we de mek di kemikal dɛn nɔ kɔmɔt na di mast sɛl dɛn.
- Leukotriene Inhibitors: Drɔg dɛn lɛk Mɔntelukast.
- Fɔ imejensi: If risk de fɔ gɛt anafylaksis, dɔktɔ dɛn advays fɔ kip ɔto-injɛkta (lɛk EpiPen) we gɛt `(epinephrine)` nia yu ɔltɛm.
Tin dɛn fɔ tink bɔt we yu de liv wit MCAS
Fɔ liv wit MCAS kin tranga, bɔt wit di rayt manejmɛnt, yu kin liv fayn fayn wan wit di kɔndishɔn.
- Di it: Sɔm it dɛn kin mek yu gɛt MCAS. Tek tɛm mɔ wit it dɛn we gɛt bɔku histamin (famɛnt chiz, tin fish, tomato, spinach, chɔklɛt). I bɛtɛ fɔ mek yu go to yu dɔktɔ ɛn go to pɔsin we sabi bɔt it fɔ mek i mek wan it plan we go fayn fɔ yu.
- Stret mεnejmεnt: Strεs na wan mεjכr trigεr fכ MCAS. So, i rili impɔtant fɔ mek yu maynd rilaks. Tin dɛn lɛk fɔ tink gud wan, fɔ du yoga, ɛn fɔ du sɔntin we yu lɛk fɔ du kin ɛp yu.
- Gɛt sɔpɔt: Tɔk to yu fambul ɛn padi dɛm bɔt yu sik. I kin fayn bak fɔ jɔyn sɔpɔt grup wit pipul dɛn we de go tru di sem kayn tin.
- Fɔ tɔk to yu dɔktɔ ɔltɛm: Tɔk to yu dɔktɔ ɔltɛm ɛn ajɔst yu tritmɛnt plan as nid de.
Mɛsej we dɛn kin kɛr go na os
- Mast Cell Activation Syndrome (MCAS) nɔto fantasi, bɔt na rial kɔndishɔn we gɛt fɔ du wit di imyun sistɛm.
- Di sayn dɛm kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin. If yu gɛt difrɛn kayn sayn dɛm wae yu nɔr ebul fɔ fɛn kɔz fɔ, go to dɔktɔ.
- Fɔ no ɛn avɔyd tin dɛm wae kin mek yu gɛt dis sik na impɔtant pat pan tritmɛnt.
- Anafylaksis na imejensi we kin mek pɔsin in layf de pan denja ɛn we nid fɔ gɛt tritmɛnt wantɛm wantɛm. Yu fɔ no di sayn dɛn we i kin gɛt.
- Wit di rayt tritmɛnt ɛn chenj na yu layf, dɛn kin kɔntrol MCAS fayn fayn wan ɛn yu kin liv nɔmal, aktif layf. Wok klos wit yu dɔktɔ fɔ du dis.
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