Prostate cancer vei tan Gleason Score i hre tawh em? I sawi dawn nia!

Doctor-in prostate cancer i nei tih a hrilh che chuan stress leh lungkhamna nasa tak i nei ngei ang, a dik em? Chutih lai chuan medical test thar leh thu buaithlak tak tak thenkhat i hre thin. I hre mai thei, i hre tawh mai thei, thumal pakhat chu ‘Gleason Score’ tih hi a ni. Chuvangin, he thu i hriat hian i hlauthawng a, "He thil thar hi eng nge ni?" Chuvangin, vawiin hian he Gleason Score hi eng nge a nih, leh i dinhmun chungchanga a sawi tak tak chu, i hriatthiam theih tur awlsam takin kan sawi dawn a ni.

Gleason Score tih hi eng nge a nih i hria em?

A awlsam zawngin, prostate cancer i neih chuan Gleason Score hi cancer awmzia tehna a ni – a hmel, a darh chak dan, engtiang chiahin nge a aggressive theih, etc. Sikul-a test-a grade pek ang mai a ni a, mahse scientific deuh leh buaithlak deuh a ni.

Hei hi pathologist ( tissue enfiah leh natna hmuchhuaktu specialist) te chuan i prostate tissue (biopsy an lak lai a thil te tak te) sample chu microscope hmanga enin cancer cell te chu eng ang nge an nih tih hriat nan an tih thin a ni. He scoring system hian doctor-te chu i tana enkawlna tha ber tur ruahmanna siam turin a pui a, enkawlna hnua i prognosis chungchang hrilhlawkna siam turin a pui bawk.

Engtin nge Gleason Score hi chhut a nih?

Okay, tunah chuan he Gleason Score siam dan hi han en ila. Ka sawi tawh ang khan pathologist te hian he hna pawimawh tak hi an thawk thin. I prostate atanga tissue sample te chu microscope hmangin uluk takin an en thin. Prostate cancer i neih chuan i prostate chhunga cell thenkhat chu cell pangngai, hrisel atanga cancer cell ah an inthlak tihna a ni .

Ngaihtuah teh, a tir lamah chuan heng cancer cell te hi cell hrisel ang maiin an lang thei. Disguised mai mai a ni. Mahse hun a kal zel a, cancer a lo zual zel chuan heng cancer cells te hi cell hrisel tak tak nen hian a danglam hle a, a pangngai lo hle bawk. Chu danglamna, chu thil danglam tak chu pathologist-te grade a ni.

Grading System hmanga siam a ni

Tissue sample tinte chu cancer cell awm dan a zirin 1 atanga 5 thleng score an pe a, chu chu cell hrisel nena an danglamna a ni. Hei hi cancer grade an ti a .

• Grade 1: Cancer cell te hi cell hrisel, pangngai ang deuhin an lang. Chu chu, danglamna a tlem hle tihna a ni. Inrem fel taka ruahman a ni.
• Pawl 2-4 inkar:Tissue chhunga cancer cell te hi cell hrisel nen a danglam deuh niin a lang a, a mumal lo zawkin a lang bawk. Grade a san chhoh zel chuan he danglamna leh mumal lo hi a langsar zual zel a ni.
• Grade 5: Cancer cell te hi a pangngai lo hle a, a inrual lo hle a, cell hrisel tak tak nen chuan a hmun atanga chhuak lo angin an lang. Hengte hi cell aggressive ber an ni.

Tunah chuan prostate cancer hian hmun khatah cell inang a nei thei a, a nih loh leh hmun hrang hrangah cell grade hrang hrang a nei thei bawk. Chuvangin, pathologist-in a tih chu cancer a darh tamna hmun ber chu thlangin grade (1-5 inkar) a pe a ni. Tichuan, a darh tam ber pahnihna (pattern danglam tak nei) chu an thlang a, grade an pe a ni. Chumi hnuah chuan grade lian pahnih chu an dah khawm leh a ni. Chu sum chu i Gleason Score a ni.

Entirnan, cancer tam ber chu grade 3 ni ta ila, a dawt leh tam ber chu grade 4 a ni ang.Tichuan Gleason score chu 3 + 4 = 7 a ni ang.Entirna dang pakhatah chuan, dominant pattern chu grade 4 a nih a, secondary pattern chu grade 3 a nih chuan Gleason score chu 4 + 3 = 7 a ni ang. Chuvangin 3+4 leh 4+3 te hi 7 ni ve ve ni mahse, doctor-te chuan a chang chuan an ngaihtuah thin heng pattern hrang hrangte hi a awm dan tur (higher grade first).

A tlangpuiin he combined Gleason score hi 6 emaw a aia sang emaw a nih chuan cancer anga ngaih a ni.

Gleason Score pangngai tih hi a awm em?

Tunah chuan i ngaihtuah mai thei, Gleason Score "normal" a awm em? Dik tak chuan Gleason Score "normal" tih hi a awm lo, kan thisen sugar level kan check hian zunthlum a awm leh awm loh kan enfiah a, kan prostate cancer PSA level kan en a, "Hetah hian normal range a awm" kan tih ang chi hi a ni. Chu ai chuan doctor-te chuan Gleason Score hi chi thum-ah ṭhenin, cancer awm dan hriatthiamna atan an hmang zawk a ni:

• Gleason score 6: Hetiang a nih chuan cancer cell te hi cell hrisel nen an inang hle. Hei hi ``well differentiated'' cancer kan ti a. A awlsam zawngin sawi ila, cell te hi "naupang tha" ang mai an la ni a, cell pangngai ang deuha siam an tum a ni. Chungte chu cancer lian lo, a na lo zawk anga ngaih an ni tlangpui.
• Gleason score 7: Hetiang a nih chuan cancer cell te hi cell hrisel ang deuhin an lang a, mahse thil dik lo engemaw zat a awm thung. Hei hi ``moderately differentiated'' cancer kan ti a. Hei hi middle ground ang a ni. 3+4=7 leh 4+3=7 inkarah hian danglamna tlem a awm thei. 4+3 pattern hi 3+4 pattern aiin condition ngaihtuahawm deuhah ngaih a ni fo.
• Gleason score 8, 9 emaw 10 emaw a ni:Hetiang a nih chuan cancer cell te hi cell hrisel te nen an danglam hle. An inrem lo hle a, an danglam bik lo tluk a ni. Hei hi cancer ‘poorly differentiated’ emaw ‘undifferentiated’ emaw kan ti a. Heng cell te hi an chetsual deuh deuh a, an thanlenna leh an darh chakna chance a sang zawk niin a lang.

Prostate cancer tan Gleason Score tha tak chu eng nge ni?

Gleason score pakhat chu "tha" emaw "tha lo" emaw tia vuah nghal a harsa hle. Mahse, i Gleason score hriat hian i doctor hnenah i prostate cancer a lo thang chak dan leh taksa hmun dangah a metastasize theih dan tur ngaihtuahna pawimawh tak a pe thei a ni. Gleason score hi 6 atanga 10 inkar a ni.

A tlangpuiin Gleason score a hniam (entir nan, 6) a nih chuan ‘low-grade cancer’ anga ngaih a ni. Heng cancer chi hrang hrangte hi a thang zawi zawi a, hmun dangah pawh a darh tlem hle.

Gleason score a sang (entir nan, 8, 9, 10) a nih chuan ‘high-grade cancer’ anga ngaih a ni. Heng cancer chi hrang hrangte hi a thang chak zawk a, a darh chak zawk bawk.

Mahse, hei hi hriat reng a pawimawh: I Gleason score hi doctor-te’n i enkawlna tur ruahmanna siamna atana an hman leh prognosis pekna atana an hman thin information pakhat chauh a ni. Chumi awmzia chu Gleason score ringawt hi a chhanna a ni lo tihna a ni. Thlalak lian zawk pakhat chauh a ni.

Gleason Score chauh hi a pawimawh em?

Ni lo, a ni lo tak zet. Ka sawi tawh ang khan i Gleason Score hi puzzle pakhat chauh a ni. Doctor-te chuan i dinhmun kimchang hrethiam tur leh i tana enkawlna tha ber an thlan theih nan thil dang tam tak an ngaihtuah a.

Entirnan, i biopsy i tih lai khan i doctor chuan i prostate atang hian sample engemaw zat, core an tih chu a la tawh mai thei. Chuvangin,

• Chu core (tissue chi hrang hrang) zinga engzat nge cancer cell awm?
• `(core)` tinah hian engzat nge cancer cell-in a khat?

Chutiang thil chu ka en ve bawk.

Chu bâkah, heng thilte hi a pawimawh hle bawk:

• I thisen `(PSA)` level. (PSA - Prostate-Specific Antigen) (thisen test bik a ni).
• Doctor-in digital rectal exam (DRE) a tih result (chu chu kut chhunga gland hriat dan a ni).
• Ultrasound scan, MRI scan, emaw PET scan ang chi specialized imaging test atanga information te hian cancer lian tham leh a darh dan hriat theih nan a pui thei a ni.
• Cancer hi prostate gland sir lehlamah a awm em tih.
• Prostate cancer hi taksa peng dang, entirnan, ruh lamah a darh (metastasized) niin an sawi.
• I kum leh i hriselna zawng zawng.

Heng zawng zawng hi dah khawm, puzzle lian tak tihfel ang chi hi, i doctor-in i dinhmun a zirin, i tana enkawlna tha ber tur chu eng nge ni tih a rel dan tur a ni. Chuvangin, Gleason score chungchangah hian a tul lovah lungngai suh, okay?

I hriat reng tur pawimawh ber (Take-Home Message) .

Okay, chuvangin kan sawi tawh atanga hriat reng tur pawimawh ber chu hetiang hi a ni. Gleason Score hi hmanraw pawimawh tak a ni a, prostate cancer hi category hrang hrangah a then a, a aggressive zia hriat theihna a pe bawk. I doctor chuan i tana enkawlna tha ber tur ruahmanna siam nan a hmang thin. Gleason Score hi 6 (low-grade, less aggressive cancer) atanga 10 (high-grade, more aggressive cancer) thleng a ni thei. Gleason Score hniam cancer hi a tlangpuiin a lo thang chak lo va, a darh theihna a tlem hle.

Mahse heng number ringawt hian i prostate cancer chungchang hi a sawi vek lo. Chu thawnthu chu i enkawl dan tur ruahmanna leh chu enkawlna atanga i beisei theih turte hriatthiamna atanga tan a ni a, chubakah a thatna leh tha lo te pawh a ni. I Gleason score leh test result dangte chu i dam leh theihna tura i zinkawng zawh tura puitu tur kaihhruaina ang mai a ni.

I Gleason Score chungchangah emaw, test result dang emaw, i damdawi lam dinhmun chungchangah zawhna emaw, ngaihtuahna emaw i neih chuan doctor zawt hreh suh. Chu number leh thumalte awmzia chu a hrilhfiah ang a, zawhna i neih apiang chu a chhang ang. He zinkawngah hian nangmah chauh i ni lo tih hre reng ang che. Chutah chuan doctor leh healthcare team te an awm a, anmahni puitu tur leh enkawltu tur che an awm bawk.

` Prostate cancer, Gleason score, cancer cells, tissue test, cancer staging, mipa hriselna, cancer enkawlna