Sri Lanka rama mi tam takin harsatna an neih chu thisen sang, a nih loh leh kan hriat vek angin "pressure" hi a ni. Chuvangin, i doctor chuan i thisen sang atan emaw, thinlung natna engemaw tan emaw damdawi a pe che a ni mai thei. Damdawi chi hrang hrang an pek zingah hian ACE Inhibitors hi damdawi chi khat a awm fo a, a pawimawh hle bawk. I damdawi hming hi Captopril, Enalapril, Lisinopril ang chi a nih chuan he damdawi chi hi i hmang ve mai thei bawk. Chuvangin vawiinah hian heng ACE Inhibitor te hi eng nge an nih, kan taksa chhunga an hnathawh dan te, kan hman laia kan hriat tur pawimawh ber berte kan sawi dawn a ni.
A awlsam zawngin, heng ACE Inhibitor te hi engte nge ni?
Hei hi a hming kimchang chu Angiotensin - Converting Enzyme Inhibitors tih a ni. A hming hi a buaithlak deuh a, mahse a tih dan chu a awlsam hle. Hei hi hrethiam tur chuan kan taksaa thil thleng tenawm tak hi han sawi ila.
Hormone leh enzyme hrang hrangte hian kan taksaa thisen sang control turin hna an thawk a. Enzyme lian ber pakhat chu `ACE (Angiotensin-Converting Enzyme) tih a ni.` He `ACE` enzyme hi kan taksaa factory tenau tak ang mai a ni. He factory hian kan taksaa thil awm `Angiotensin I` chu thil chak dang `Angiotensin II` tih ah a chantir thin.
Tunah chuan he tlangval `Angiotensin II` tih hi kan thisen sang tisangtu a ni. Thil pawimawh pahnih a ti a:
1. Blood vessels constrict (constrict): Tui pipe an hrual chuan tui a luang chak zawk ang bawkin, thisen kalna kawng a inkhauh chuan thisen kalna tur hmun a tlahniam a, thisen kalna kawng chhunga pressure a sang chho zel bawk.
2. Kal atanga chi leh tui paih chhuah a tikhawtlai: Taksaah chi leh tui tam lutuk a awm reng chuan thisen volume a tipung a, chu chuan thisen sang a tisang bawk.
Chuvangin ACE inhibitor hian a tih chu ka sawi tawh ang khan chu factory `ACE` tih chu a titawp a ni. Chu chu thisen sang tisangtu hormone `Angiotensin II` siam chhuah a ti tlem tihna a ni.
Chu mai a ni lo, he `ACE` enzyme hian protein pakhat `Bradykinin` an tih chu a tichhia a, chu chu kan taksa tana tha tak a ni a, thisen kalna kawng a tizau bawk. ACE inhibitor i ei hian, `ACE` enzyme hian hna a thawh loh avangin, chu protein tha tak `Bradykinin` tih chu taksaah a awm tam zawk a ni.
A awlsam zawngin sawi ila, ACE inhibitor hian thisen sang tisangtu thil siam chhuah a titawp a, thisen sang tihhniamtu thil hloh tur a veng bawk. He dual action hian thisen sang control tha takin a pui a ni.
Eng dinhmunah nge doctor-te hian he damdawi hi an pek?
ACE Inhibitors hi thisen sang damdawi chauh a ni lo. Thinlung leh kal venhimna kawngah pawh an pui a, chuvangin doctor-te chuan natna chi hrang hrang atan an pe thin.
- Thisen sang control: 1.1.Hei hi hun remchang pawimawh ber leh hman tlanglawn ber a ni.
- Heart Failure enkawl: Thinlung hian thisen a pump tling thei lo a nih chuan he damdawi hian thinlunga hnathawh tur a tihziaawm bakah a hnathawhna kawngah a pui bawk.
- Heart Attack hnua: He damdawi hi heart attack hnua a lo harh leh theih nan leh a chhiat belh zel tur venna atana pek a ni.
- Zunthlum vei te kal (kidney) venhim: Zunthlum hian hun kal zelah kal (kidney) a tichhe thei a ni. ACE inhibitor hian chu chhiatna chu a tikhawtlai thei a, a veng thei bawk.
- Heart attack leh stroke vei hlauhawmna sang tak nei tan: Hengte hi hlauhawma awmte zingah heng natna lo thleng tur venna atan pawh pek a ni.
- Kal natna dang tan: Hengte hi kal natna thenkhat (`Nephrotic syndrome`, `Proteinuria` ang chi) tan pawh hman a ni a, chu chu zunthlum vei lote tan pawh a ni.
ACE inhibitor chi hrang hrang hman tam berte chu engte nge ni?
ACE inhibitor chi hrang hrang hi market-ah a awm a. I damdawi hian a hnuaia hming tarlan zinga pakhat a nei thei. Damdawi generic name chu inang mahse, company hrang hrang siam a nih avangin brand name a inang lo thei tih hre reng ang che.
| Damdawi hming Generic | Brand hming thenkhat (Entirnan Brand hming) . |
|---|---|
| Benazepril a ni | Lotensin® hmanga siam a ni |
| Captopril a ni | Capoten® tih a ni |
| Enalapril a ni | Vasotec® hmanga siam a ni |
| Lisinopril chuan a ti a | Zestril® tih a ni |
| Ramipril chuan a rawn ti a | Altace® a ni |
| Perindopril a ni | Aceon® a ni |
He damdawi hi engtin nge ka hman ang?
Mi tam zawk chu ni khatah vawi khat ACE inhibitor an pe thin. Mahse, mi thenkhat chuan ni khatah vawi hnih ei a ngai mai thei. Hei hi i doctor-in a rel tur a ni.
Thil pawimawh tak chu dose i miss a nih chuan eng nge i tih tur tih hi a ni. I zing dose ei kha i theihnghilh ang tih han ngaihtuah teh. Nilengin i hre reng a nih chuan i hriatreng veleh ei nghal rawh. Mahse a tuk zingah i hre reng a, chu chu i dose leh tur hun a ni tawh tihna a nih chuan missed dose kha ei suh. Skip la, a hun ruatah dose dang ei mai rawh. Vawi khatah pill pahnih ei ngai suh, i theihnghilh tawh nen chuan. Chutianga tih chuan i thisen sang a tlahniam lutuk a, luak chhuak a thlen thei bawk.
Thil pawimawh dang pakhat chu, he damdawi hi doctor nena inbia lovin i ei thut loh tur a ni. Chutianga i tih chuan i thisen sang chu a sang nghal thei a, chu chuan heart attack emaw stroke emaw i neih theihna a tipung thei a ni. Damdawi ei nuam lo ti thei tur side effect i neih chuan doctor hnenah hrilh rawh. I tana tha zawk damdawi dang ah a switch ang che.
He damdawi hian eng hlawkna leh side effect nge a neih?
ACE Inhibitors hi khawvel hmun hrang hranga doctor-te’n chhan hrang hrang avanga an rinchhan damdawi chi khat a ni.
A thatna ber
- A hlawk em em: Scientific research atanga a lan dan chuan hengte hi thisen sang leh lung natna tihreh nan a tangkai hle a ni.
- Natna a veng: Natna awmsa a enkawl mai bakah, nakin lawka heart attack, stroke, leh kal natna te a veng thei bawk.
- Damdawi dang nena inmil: A châng chuan doctor-te chuan ACE inhibitor leh thisen sang damdawi dang inzawmkhawm pill pakhat an pe ṭhin.
- Safe: Heng damdawi te hian a tlangpuiin side effect a nei tlem hle. Side effect na tak tak a awm tlem avangin dam chhung atan him takin hman theih a ni.
Side effect awm thei te
Damdawi dang ang bawkin, hengte hian mi thenkhatah side effect tenau te a thlen thei a ni.
| Side effect a awm thei | Hrilhfiahna |
|---|---|
| Dry cough a ni | Hei hi ACE inhibitor te side effect tlangpui leh tlangpui a ni. Phlegm awm lo, hacking cough awm reng. Hei hian a tibuai che a nih chuan doctor hnenah hrilh rawh. |
| Luak chhuak thei | Hei hi thut atanga i ding nghal mai hian a thleng thei a, a bik takin damdawi i ei tan tirh hian a thleng thei a ni. Chuvangin zawi zawiin tho rawh. |
| Lu na leh hah lutuk | Mi thenkhat chuan an tawng ve mai thei. |
| Angioedema a awm thin | Hei hi natna awm lo mahse na tak a ni. Hmai, hmui, lei emaw, kawr emaw a ti na nghal a ni. Hei hian thawk harsatna a thlen thei a ni. |
| Midang (a tlem hle) . | Ka chhunga metallic taste, luak chhuak, vun rawng chhuak. |
He damdawi hman huna fimkhur tur thilte
He damdawi ei loh tur mite
- Nu naupai emaw, nau hnute pe lai emaw. (Naute i beisei a nih chuan i doctor hnenah hrilh lawk rawh.)
- Tun hmaa angioedema (hmai hring) nei tawhte.
- Kidney natna khirh tak emaw renal artery stenosis nei te.
Damdawi dang nena inzawmna
ACE inhibitor i ei a nih chuan damdawi dang i ei zawng zawng (vitamin pawh) i doctor hriattir a pawimawh hle.
- Painkillers (NSAIDs): Painkillers Ibuprofen leh Diclofenac te hi hman fo a nih chuan ACE inhibitor te thatna a ti tlem thei a, kal a tichhe thei bawk.
- Potassium level tichhe thei damdawi: Damdawi thenkhat hian taksaa potassium level chu a tul lovah a tipung thei (hyperkalemia).
- Chi leh chi aiah: Chi i ei tur zat chungchangah doctor rawn la. Tin, potassium awmna "salt substitute" i hman hmain doctor zawt hmasa phawt ang che.
Engtikah nge damdawi lam thurawn i lak nghal ang?
A hnuaia chhinchhiahna na tak tak te hi a lo awm a nih chuan damdawi in hnai ber Emergency Department (ETU) pan nghal tur a ni.
| Emergency - Damdawi inah kal nghal rawh! | |
|---|---|
| Hmai, hmui, lei emaw, kawr emaw a hring | Hei hi `Angioedema` a ni thei. Thâwk harsatna thlen thei dinhmun na tak a ni. |
| Allergy symptom na tak tak a awm | Vun vun rawng, natna nasa tak, ei leh thawk harsa. |
| Mutthilh emaw, muhil emaw tih hriat | A tul lova thisen sang tlahniam chhinchhiahna a ni thei. |
| Heart attack emaw stroke emaw chhinchhiahna | Chhung natna nasa tak, thawk harsa, hmai emaw taksa sir khata bengchheng, tawng harsa. |
| Vun emaw mit emaw a sen (Jaundice) . | Hei hi liver function lama harsatna lian tak a awm tih chhinchhiahna a ni thei. |
ACE inhibitor i ei a nih chuan i doctor chuan kum khatah vawi khat tal thisen leh zun test vawi tam tak a ti mai thei a, chu chuan i kal hnathawh leh thisen chi (blood salt level) a enfiah ang. Heng test te hi skip loh a pawimawh hle.
Take-Home Thuchah a ni
- ACE Inhibitors hi thisen sang, thinlung natna, leh kal natna enkawlna atana hman thin damdawi class pawimawh tak leh tangkai tak a ni.
- Damdawi hi i doctor-in a pek ang chiah chiah, a hun takah leh a dose dik takah ei thin ang che.
- Eng thil vang pawha doctor rawn hmasa lovin i damdawi ei kha titawp thut suh.
- Persistent dry cough i neih chuan doctor hnenah hriattir tur a ni.
- Hmai, hmui emaw, kawr emaw a hring, thawk harsa tih ang chi symptom na tak tak i neih chuan damdawi in Emergency Department (ETU) pan nghal tur a ni.
- Damdawi dang i ei zawng zawng (painkiller leh vitamin te pawh tel) i doctor hnenah hrilh rawh.
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