Metformin, zunthlum natna atana hman thin chungchang i zir dawn teh ang? (Biguanides) te chuan an ti a.

I doctor-in zunthlum i vei tih a hrilh che chuan damdawi hmasa ber chu Metformin a ni mai thei. Hei hi zunthlum damdawi lar tak leh him tak a ni a, Sri Lanka-ah chauh ni lo, khawvel hmun hrang hrangah pawh a lar hle. Mahse, damdawi thar kan tan dawnin zawhna tlemte leh hlauhna tlem kan neih hi kan zavaiin thil pangngai a ni. Tin, "Hei hi eng nge thleng ang?", "Hei hi taksa tan a tha em?", "A side effects a awm em?" Ngaihtuah buai suh, vawiin hian he damdawi class Metformin, chu chu Biguanides tih hi i hriatthiam theih tur awlsam takin kan sawi dawn a ni.

A awlsam zawngin, heng Biguanides te hi eng nge ni?

Biguanides hi zunthlum venna atana hman thin damdawi chi khat a ni. Pill angin an ei thin. Type 2 Diabetes vei enkawlna atan an hmang ber a ni . Heng damdawi te hnathawh ber chu i thisena sugar, a nih loh leh glucose level tihhniam leh control hi a ni.

Tunah chuan, "Biguanides pawlah hian ruihhlo tam tak a awm em?" A tak tak lo. Tunah hian khawvel ram tam zawkah, Sri Lanka telin, he pawl hnuaiah hian damdawi pakhat chauh a awm a ni. Chu chu kan hriat vek Metformin chu a ni. Mahse, damdawi Metformin hi brand hming hrang hrangin i hmu mai thei. Entir nan:

• Glucophage® hmanga siam a ni
• Glucophage XR® hmanga siam a ni
• Glumetza® hmanga siam a ni
• Fortamet® hmanga siam a ni
• Riomet® hmanga siam a ni

Eng hming pawh nei mahse a chhunga active ingredient chu a inang vek a, chu chu Metformin a ni.

Metformin hi zunthlum tan chauh pek a ni em?

Metformin hi type 2 diabetes tan phalsak a ni ber. Dik tak chuan chutiang tur chuan first-line therapy anga ngaih a ni. Chu chu, zunthlum a hriat veleh doctor-in a tan tirh tur damdawi hmasa ber a ni tihna a ni.

Mahse, doctor-te chuan he damdawi hi zunthlum chauh ni lovin, natna dang engemaw zat atan an pe a ni. Hei hi "off-label" hmanna kan ti a. Chu chu, doctor-te chuan official-a phalna pek a nihna bakah hian natna dang atan an pe a, a thatna avang hian.

Hei bakah hian tunah hian zirchiangtute chuan metformin hian cancer dona a nei em tih an zirchiang mek bawk. Zirchianna thenkhatah chuan zunthlum natna atana metformin ei thinte hian cancer vei theihna an nei tlem zawk tih hmuhchhuah a ni. Mahse, hengte hi zirchianna stage-ah an la awm a ni.

Engtin nge he Metformin pill hian kan taksa chhungah hna a thawh tak tak?

Hei hi zawhna pawimawh tak a ni. He damdawi hian hna a thawh dan tlangpui pahnih a awm. Entirna awlsam tak hmangin i hrethiam ang u.

I taksa chhungah sugar (glucose) siamna factory lian tak i nei ang tih han ngaihtuah teh. Chu chu i liver a ni . Zunthlum vei tan chuan he factory hi a thawk tam lutuk a, thisenah sugar a pump chhuak fo thin.

1. Liver-in sugar a siam chhuah tihtlem: Metformin hian a tih hmasak ber chu sugar factory (liver)-a sugar siam chhuah tihtlem a ni. Phên dangin sawi ila, he damdawi hian thin atanga thisenah a tul lo taka sugar dah belh chu a thunun a ni.

2. Muscle te hi insulin lakah an sensitive lehzual: Thil pahnihna chu kan taksaa hormone insulin hnathawh thatna tura puih hi a ni. Insulin hi kan taksa cell kawngkhar chabi ang a ni. He key hi thisen chhunga sugar awm chu cell chhunga lut a, chakna siam theitu a ni. Zunthlum vei te hian he chabi hi hawn harsa an ti hle. Kan ti mai thinInsulin laka invenna a ni. Metformin hian taksa ruh ang chi cell kawngkharte chu he key (insulin) hi a dawng thei zawka siamin hna a thawk a ni. Tichuan thisen chhunga sugar awm chu awlsam takin cell chhungah a lut thei a, chakna ah a inthlak thei bawk. Tichuan thisen sugar level a tlahniam ta a ni.

PCOS vei hmeichhiaah chuan Metformin hian insulin level a tihhniam a, hei hian androgens ang chi hormone level a tihhniam a, thlasik hun pangngai a siam that theih nan a pui bawk.

He damdawi hian eng hlawkna nge a neih?

Metformin hi damdawi tha tak a ni.

• A1C level tihhniam: Zunthlum vei tan chuan metformin hian an A1C level (thla 2-3 kalta chhunga thisen sugar level averages test-na test) chu 1% velin a tihniam thei a ni. Hei hi zunthlum enkawlna kawngah hmasawnna lian tak a ni.
• Diabetes venna: Zirna hrang hrangah he damdawi hian prediabetes vei te zingah full-blown diabetes lo awm tur chu a tikhawtlai emaw, a titawp vek emaw thei tih hmuhchhuah a ni.
• Lung natna vei theihna tihziaawmna: Zirchianna thenkhatah chuan metformin hian rilru lam natna vei theihna a tihziaawm thei bawk.

A pawimawh ber chu he damdawi hi dam chhung zawnga natna a nih avangin doctor nena inbiak reng a, i damdawi leh nunphung thlak danglam (diet, exercise) te chu a hrilh angin ei a pawimawh hle. Damdawi chauh hian zunthlum hi a thunun thei lo.

Side effect leh risk te pawh i hrechiang ang u.

Damdawi dang ang bawkin Metformin hian side effect engemaw zat a nei thei a ni. Mahse heng zinga a tam zawk hi chu a serious lo va, mi zawng zawngin kan hmu vek lo.

Side effect awm fo thin

Hengte hi damdawi ei tan hnu ni engemaw zat emaw, kar hmasa berah emaw a thleng thei. Taksain damdawi a insiamrem chhoh zel avangin hun kal zelah an bo tlangpui.

• Pum natna: Pumthaw, luak chhuak, luak chhuak, a bik takin luak chhuak hi a side effect tam ber a ni. Hetiang dinhmun hi metformin ei thin zinga 30% vel ah a awm thei.
• Chaw ei zawha damdawi ei: Hetiang taka pum na lo tihziaawmna tha ber chu chaw ei rual emaw, chaw ei zawh veleh emaw damdawi ei hi a ni. Pum ruak ah ei loh tur.

Side effects awm lo tak tak

• A rilru a hah lutuk
• Lu na
• Thaw hah lutuk (diaphoresis) .
• Thisen thlum hniam (hypoglycemia) - (Hei hi Metformin chauh hmang hian a awm lo hle a, mahse zunthlum damdawi dang nena ei chuan a thleng thei)
• Chaklohna

Chungte chu a awm reng emaw, harsatna a thlen emaw chuan i doctor nen inbia ang che.

Risk situations ngaihven bik ngai te

Metformin hi a tlangpuiin damdawi him tak a ni a, mahse harsatna lian tham tak tak, a awm tlem hle thei te hriat a pawimawh hle.

1. Vitamin B12 tlakchhamna

Metformin hi rei tak i ei chuan i taksa hian vitamin B12 a hip tlem deuh mai thei. Chuvangin, i doctor chuan i vitamin B12 level a enfiah thei a, a bik takin thisen tlakchhamna emaw, peripheral neuropathy emaw i neih chuan. A tul chuan vitamin B12 supplement ei turin a rawt thei bawk.

2. Lactic Acidosis natna (Lactic Acidosis) a awm thin

Lactic acidosis hi taksain lactic acid a siam tam lutuk avangin thisen a acidic lutuk a ni. He natna hian metformin ei thin mi 30,000 zinga 1 vel a nghawng a ni. Hei hi a tlem hle. Mahse, nunna atana hlauhawm a nih avangin a natna lan chhuah dan hriat a pawimawh.

Lactic acidosis vei theihna chance sang zawk nei te:

• Kidney emaw liver natna nei te
• Kum 65 chunglamte
• Tun hnaia operation nei tawhte
• Hypoxia (taksa a oxygen tlakchhamna) vei te .
• Zu in tam lutuk te

I doctor chuan Metformin i pek hunah i kal hnathawh dan a enfiah fo ang a, hei hi he hlauhawmna hi a chhan theih nan a ni.

Lactic acidosis natna lan chhuah dan:

Heng symptoms zinga pakhat emaw a aia tam emaw a lo awm thut chuan damdawi ei kha bansan nghal la, hospital emergency room (ETU) hnai ber pan rawh.

• Chauhna leh chak lohna nasa tak
• Nausea leh luak chhuak
• Pum a na
• Thâwk rang emaw rei tak emaw, thûk taka thawk

Hetiang dinhmun hi enkawl vat loh chuan thihna pawh a thlen thei a, chuvangin heng symptoms te hi fimkhur hle ang che.

3. Damdawi dang nena harsatna (Drug Interactions) .

Metformin i ei a, natna dang atan damdawi dang i ei a nih chuan doctor hrilh a pawimawh. Damdawi thenkhat hian metformin nen an inzawm thei a, lactic acidosis vei theihna a tipung thei bawk. Damdawi thenkhat chuan thisen thlum (hypoglycemia) a thlen thei bawk. I damdawi ei zawng zawng (vitamin, supplement, leh herbal remedies te pawh tel) chu i doctor hnenah hrilh ngei ang che.

Engtikah nge Doctor ka hmuh ang?

Metformin i ei dawnin doctor-in a tih angin a hun ruatah clinic-ah i kal tur a ni. Chutiang chuan damdawi chu a thawk tha em tih te, a dose thlak a ngai em tih te, leh side effects a awm em tih te a hmu thei ang.

Chu bakah, a hnuaia thil awm danah hian i doctor nen inbia ang che:

• Side effects in a tibuai che emaw, tuar harsa emaw a nih chuan.
• I zunthlum emaw PCOS natna emaw chu damdawi hmanga control tha lo nia i hriat chuan.
• Eng thil vang pawha damdawi ei khap a ngai nia i hriat chuan doctor rawn hmasa lovin damdawi ei kha bansan ngai suh.

Metformin hi damdawi him leh tangkai tak a ni a, khawvel hmun hrang hranga mi maktaduai tam takin kum sawm tam tak chhung an lo hmang tawh a, zirchianna tha tak an nei tawh a, an tuar thiam hle bawk. Chuvangin zawhna zawh hreh suh. Zawhna emaw, ngaihtuahna emaw i neih chuan i doctor nen zalen takin sawipui rawh. I tanpui turin a inpeih reng a ni.