I chak lo tih i inhria em? I kut leh ke te chu a tingling em? CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) chungchang hi i zir dawn teh ang!

A châng chuan i chau hle tih i hria em, i kut leh ke a hrual a, a nih loh leh i tingling sensation i nei em? A châng chuan heng thilte hi i ngaihven vak lo mai thei. Mahse, a tlem berah chuan heng symptoms te hi thil pawi zawk chhinchhiahna a ni thei. Chutiang dinhmun hmuh tur awm lo mahse hriat tur pawimawh tak pakhat chu CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) tih a ni. A hming hi sei deuhin lang mahse, a awlsam zawngin i dah ang u.

CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) hi eng nge ni?

He hming hi a buaithlak deuhin lang mahse, a awmzia kan tihchhiat chuan he natna hi a chiang zawkin kan hre thei ang.

• Chronic: Hei hi "hun rei tak chhung" tihna a ni. Chumi awmzia chu CIDP hi a lo thleng nghal lo va, a dam thuai lo tihna a ni. Zawi zawiin a lo thang lian a, kar riat tal chhungin a lo thang lian thin. A châng chuan a natna lan chhuahna chu a reh a, thla tam tak emaw, kum tam tak emaw hnuah pawh a rawn lang leh ṭhin. Buaina lo thleng leh zel ang mai a ni.

• Inflammatory: Hei hian "inflammation" tihna a ni. Kan taksa hmun dangah hliam kan neih chuan a hring a, a sen vek a ni lawm ni? Chu chu a ni. Mahse CIDP-ah chuan he inflammation hi kan taksa ngeia immune system- a harsatna engemaw vang a awm thin . A awlsam zawngin kan taksa humhim tur sipaite hian kan nerve ngei pawh hi kan bei sual tan thin. Hei hi Autoimmune Attack'' an ti a. Hei vang hian inflammation nasa lutuk hian kan peripheral nerves a tichhia a ni . Heng peripheral nerve te hi thluak leh ruhro atanga chhuak nerve te an ni.

• Demyelinating: Hei hi thumal thuk deuh a ni. Kan neurons te hian an chhehvelah hian venhimna khuh an nei a. Electric wire vel plastic sheath ang mai a ni. He khuhna hi (Myelin Sheath) an ti a . He myelin sheath hian nerve message te chu rang tak leh dik taka kal theihna a siam a ni. (Demyelinating) tih awmzia chu myelin sheath a chhe emaw, a chhe emaw tihna a ni. Tichuan, wire-a plastic awm chu lakchhuah a nih ang bawkin current chu a leak a, nerve message te chu a kal tha lo hle.

• Polyneuropathy: "Poly" tih awmzia chu "tam tak" tihna a ni. "Neuropathy" tih awmzia chu nerve tihchhiat tihna a ni. Polyneuropathy tih awmzia chu taksa chhunga peripheral nerve tam tak a ruala tihchhiat tihna a ni. Hei hian harsatna hrang hrang a thlen thei a, chu chu taksa ruh chak lohna, rilru hahna, leh paresthesia te hi a ni.

Chuvangin, a awlsam zawngin, CIDP hi hun rei tak chhunga awm, kan taksa hriselna (immune system) a tha lo vanga peripheral nerve chhehvela myelin sheath a chhiat avangin nerve tam tak a thawk tha lo a ni. I hrethiam em?

Guillain-Barré Syndrome (GBS) leh CIDP hi eng nge an danglamna?

I ni ngei ang (Guillain-Barré Syndrome) emaw (GBS) emaw tih i hre tawh mai thei. Natna CIDP hi GBS nen a inang hle. Doctor-te chuan CIDP hi hun rei tak chhunga GBS chi khat niin an ngai. GBS hi natna hmuh tur awm lo tak a ni bawk a, kan immune system hian peripheral nerves a bei thin.

Mahse a danglamna ber chu hun a ni. GBS natna khirh ber chu a lan chhuah tan atanga kar hnih atanga kar thum hnuah a lo thleng tlangpui. Mahse mi tam zawk chu chu mi hnuah chuan an dam zauh zauh thin. Mahse CIDP hi a rei zawk. Kar riat tal chhungin natna lan chhuah dan chu a na zual zauh zauh thin .

CIDP hi engtiang chiahin nge a awm?

CIDP hi a takah chuan a awm lo hle . Zirchiangtute sawi danin, United States-a CIDP vei thar zat hi kum khatah mi 100,000-ah 0.8 leh 8.9 inkar a ni. He range hi a lian deuh a, a chhan chu CIDP hian mi hrang hrang a nghawng thei a, a chhan chu natna hi hriat a harsat vang a ni.

CIDP hi kum eng pawhah a lo thang chak thei.

CIDP natna lan chhuah dante chu engte nge ni?

CIDP natna lan chhuah dan hi a chi hrang hrangah a inang lo thei. Mahse, a lan chhuah dan tlangpui chu taksa ruh chak lohna zual zel a ni a, kar riat tal a awm thei. Hei hian taksa sir lehlamah inang tlangin a nghawng tlangpui. A bik takin:

• Hip leh thigh area chhunga muscle te
• Kawngkhar leh kut chunglam area muscle te
• Kut leh kut zungtang
• Ke leh ke ruh

Ngaihtuah teh, ṭhutphah aṭanga tho chu i harsat thut a, stairs flight i lawn thei lo ang maiin i inhria a, i sam i hrual emaw, no i vawn emaw pawh i harsat phah a ni. Hetiang thil hi a thleng thei a ni.

Symptom dang hmuh theihte chu:

• Atrophy chu a natna nei taksa peng hrang hrangte a ni
• Kut zungtang leh ke ruh natna, rilru hahna, emaw hriatna hloh (Paresthesia) .
• Taksa balance vawn that harsatna leh coordination tha lo (tluk ang chi) .
• Kal harsa emaw, kea kal hloh vek emaw
• Deep tendon reflexes hloh emaw chak lo emaw (hei hi doctor-in khup chu hammer te tak te hmanga a tap-a a test tur a ni) .
• Neuropathic Pain natna a ni. Hei hi kang emaw electric shock emaw ang maia natna a ni.

A tlem hle a, hetiang symptoms hi i hmu thei bawk:

• Chaw ei harsa (Dysphagia) leh kawr chunglam chak lohna
• Double Vision a awm

Heng symptoms te hi hun kal zelah a danglam thei a ni. Zawi zawiin an tan thei a, a nih loh leh hma an sawn chak hle thei bawk. A châng chuan an lo kal a, an kal a, ni engemaw zât hnuah an reh a, an lo kir leh thei bawk. Heng symptoms te hi i neih chuan a rang thei ang bera Doctor pan a pawimawh.A hmaa hriatchhuah leh enkawl hian damna kawngah kawng thui tak a zawh a ni.

CIDP chi hrang hrang a awm em?

Ni e, CIDP hi chi hrang hrang a awm a, an symptom pawh a inang lo deuh bawk.

A chi tlangpui chu typical CIDP , taksa sir lehlamah taksa ruh chak lohna leh sensory symptoms (numbness ang chi) a thlen thin.

Atypical variant thenkhat chu:

• (Multifocal Motor Neuropathy): Hei hian taksa ruh chak lohna chauh a huam a ni. He chak lohna hi asymmetrical a ni bawk a, chu chu taksa sir khatah hmun khat chauh a nghawng thei tihna a ni a, a nih loh leh hmun engemaw zat chu kawng hrang hrangin a nghawng thei tihna a ni.
• (Lewis-Sumner Syndrome): Hei hian asymmetric muscle chak lohna leh sensory symptoms te a huam vek a ni.
• (Pure Sensory CIDP): Hei hian rilru hahna, natna, balance lama harsatna, leh kal dan pangngai lo a thlen thei. Mahse taksa chak lohna a awm lo.
• (Pure Motor CIDP):: Hetah hian taksa peng lehlamah nghawng nei taksa chak lohna leh reflexes hloh hmuh tur a awm a, mahse sensory symptoms a awm lo.

Researcher te chuan CIDP variant dang pawh an la zirchiang mek a ni.

Eng thilin nge CIDP hi a thlen?

Kan sawi tawh ang khan zirchiangtute chuan CIDP hi kan immune system a tha lo vang niin an ngai . A chhan dik tak hriat ni lo mah se, kan immune system chuan myelin sheath chu hmelma angin a hmu a, chutah chuan a bei tan ta a ni (an autoimmune reaction).

Myelin sheath hi kan nerve cell vel a venhimna layer a ni. Nerve fiber (axon) sei tak chu a khuh a ni. Myelin hi electrical impulse te chu nerve kaltlanga dik taka kal tir theitu a ni. Myelin a chhiat chuan heng electrical impulse te hi a kal zawi hle a, a nih loh leh a bo vek a ni. Tichuan "message" te chu an kalna tur hmunah an thleng lo. Chu chu CIDP symptoms thlentu a ni.

Electrical wire insulation tha tak chu han mitthla teh. Current mawi takin a conduct thin. Mahse, chu wire-a plastic sheath chu hmun ṭhenkhatah a lo chhuak a nih chuan eng nge thleng ang? Current a leak emaw, a luang tha lo emaw a ni lawm ni? Chu chu myelin sheath a chhiat chuan a thleng thin.

Engtin nge CIDP hi hmuhchhuah a nih?

CIDP hi hriat chian a harsa thei a, a chhan chu chi hrang hrang hian symptom hrang hrang an nei a ni. CIDP hriat chian nan i doctor chuan:

• I symptoms te uluk takin an ngaithla ang a , i medical history an zawt ang .
• Taksa enfiahna leh thluak lam enfiahna (neurological exam) an nei thin.
• Diagnosis hriat chian nan emaw, natna dang a awm loh nan emaw special test engemawzat tih a ni thei bawk.

CIDP hriat theihna atan eng test nge hman thin?

Hengte hi CIDP nemnghet thei tur leh a chhan dangte paih chhuah theihna tur test te chu an ni:

• Electromyography (EMG) leh Nerve Conduction Test: Heng test te hian i taksa ruh hriselna leh hnathawh dan leh a thununtu nerve te a en thin. Heng test te hi CIDP ang chi demyelinating changes (nerve signals slow transmission, blockages, etc.) zawn nan a tangkai hle. Hei hian CIDP hi polyneuropathie chi dang hman tlanglawn tak atanga thliar hrang turin a pui thei a ni.

• Spinal Tap / Lumbar Puncture: He test-ah hian doctor chuan i hnungzang hnuai lamah needle te tak te a dah a, i cerebrospinal fluid (CSF) sample a la a ni. He sample hi test turin lab-ah thawn a ni. CIDP vei zinga 85% atanga 90% velah chuan thisen var (white blood cell count) chu a pangngai a, mahse protein level a sang hle. CSF-a thil danglam dangte chuan dinhmun dang a kawk thei bawk.

• Magnetic Resonance Imaging (MRI) scan of the lower back: I hnungzang hnuai lam nerve roots te hian MRI scan laiin contrast dye an absorb a nih chuan CIDP hriatchhuahna kawngah a pui thei a ni.

• Thisen Test: I doctor chuan neuropathy thlen thei natna dang, zunthlum, vitamin tlakchhamna, thyroid natna, Lyme natna, HIV/AIDS, leh lymphoma te chu a hriat loh nan thisen test a ti thei ang . CIDP nena inzawm nia hriat antibody thenkhat an enfiah thei bawk.

• Nerve Biopsy: A tlem hle a, doctor chuan nerve biopsy tih a rawt thei a, chutah chuan nerve pakhat chu lakchhuah a ni a, myelin sheath a chhiat leh chhiat loh enfiah a ni.

CIDP enkawlna tur engte nge ni?

CIDP hi enkawlna bulpui (first-line) pathum a awm a, chungte chu:

• Corticosteroids: Steroid damdawi, prednisolone te hian inflammation tihziaawmna a pui thin. Mi tam tak tan chuan heng steroid chauh hian natna lan chhuahna a tihziaawm thei a ni. Mahse, steroid hian side effect na tak a nei thei a, chuvangin heng damdawi te hi hun rei tak hman hi a tlem hle. I doctor chuan steroid bakah damdawi dang (immunosuppressants) a pe thei bawk.

• Plasma Exchange / Plasmapheresis: Hetiang enkawlnaah hian machine pakhatin i thisen atanga plasma chu a then a, a enkawl a, chumi hnuah plasma leh thisen chu i taksaah a rawn thawn let leh thin. A awlsam zawngin, plasma-a i nerve beitu antibody tha lo tak takte chu a filter chhuak vek a ni. Plasma exchange hian kar tlemte chhung chauh a thawk tlangpui. He enkawlna hi thla tam tak chhung, kum tam tak chhung pawh on leh off i mamawh mai thei.

• Intravenous Immunoglobulin Therapy (IVIG): He enkawlnaah hian immunoglobulins (kan immune system-in a pianphung anga invader-te bei tura a siam protein) an tih chu thisenah (IV) pek a ni. He immunoglobulin hi mi hrisel sang tam tak thisen atanga lak chhuah a ni. IVIG hian i immune system-in i nerve a tihchhiat chu a ti tlem thei a ni. IVIG hi a tir lamah chuan dose sang takin pek a ni thei a, thla tam tak chhung, kum tam tak chhung pawh he enkawlna hi a hun hunah pek a ngai mai thei bawk.

Tunah hian zirchiangtute chuan CIDP enkawlna dang an zirchiang mek a ni. CIDP tana clinical trial-ah pawh tel theihna hun i nei thei bawk. Hemi chungchang hi i doctor nen sawiho rawh.

CIDP nen hian nun hi eng ang nge ni? (Prognosis) tih a ni.

Hun rei tak chhunga natna awm dan tur chu thil engemaw zatah a innghat a ni:

• CIDP a lo intan tirh khan i kum .
• Natna lo awm dan leh natna chi hrang hrang .
• Engtiang chiahin nge natna hi hmuhchhuah a nih thuai a, enkawl tan a nih thu .
• I taksain a tir lama enkawlna a dawn dan .

CIDP vei zinga 90% vel chu enkawlna hmangin an dam thei a ni. Mahse mi 50% vel chuan relapse an nei thin. A tlangpuiin, kum naupan lai atanga CIDP vei hmuhchhuah te hun rei tak chhunga an hmalam hun tur (long-term prognosis) hi a tha hle. CIDP enkawlna engmah i hmuh loh chuan permanent nerve damage a awm thei a, chu chuan disability engemaw zat a thlen thei a ni.

I doctor chuan i dinhmun bik a zirin hmalam pan tura i beisei tur chu a ngaihtuah tha thei ang che.

CIDP hian dam rei zawng a ti tawi em?

CIDP hi thihna thlen thei natna a ni lo. He natna vei te hian he natna nei lo te nen hian dam rei zawng an inang tlangpui. Chuvangin ngaihtuahawm tur a awm lo.

CIDP hi ven theih a ni em?

A chhan chu zirchiangtute chuan CIDP thlen chhan chiang tak an la hmu lo a, tun dinhmunah chuan he natna lo awm tur ven dan tur hriat a la awm lo.

Engtikah nge Doctor ka hmuh ang? / Engtikah nge emergency room-ah ka kal ang?

CIDP i vei tih hmuhchhuah i nih chuan i natna lan chhuah dan enfiah turin doctor i pan fo tur a ni a, enkawlna i dawng tur a ni. CIDP symptoms hi thla tam tak emaw, kum tam tak emaw chhung pawh a lo thleng thei a, chuvangin enkawl chhunzawm zel a ngai mai thei.

A tlem hle a, CIDP hian thawk chhuahna atana mamawh taksa ruhte a nghawng thei . Thâwk lak harsatna i neih chuan 911 (or i awmna hmuna emergency number) call nghal la, a nih loh leh emergency room hnai ber pan rawh. Hei hi emergency a ni.

A tawp berah chuan thil hriat reng tur

I taksa thunun thei lo anga inhriat chu a hlauhawm thei hle. Mahse thu lawmawm tak chu CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) symptoms te hi enkawl theih a ni a, a bik takin enkawl tan hma chuan. He natna hi hmachhawn tur hian i medical team te chu i bulah an awm reng tih hre reng ang che. Chuvangin thinlung takin i doctor thurawn zawm rawh.