Cancer do hi thil awlsam a ni lo tih kan hria. Mahse tunlai damdawi lama hmasawnna avang hian cancer cell chauh target thei leh enkawl thei damdawi a awm ta. Pralsetinib hi chutiang damdawi bik, ‘targeted’ pakhat a ni. Chuvangin, nangmah emaw, i hmangaih tak emaw hnenah he damdawi hi i lo pe tawh a nih chuan, awlsam tak, friendly takin i sawi dawn nia.
Pralsetinib hi eng damdawi nge ni?
A awlsam zawngin sawi ila, Pralsetinib hi cancer cells te tihpunna tura puitu protein bik target a, an hnathawh titawptu damdawi a ni. Cancer cell-a ‘switch’ hmuh ang maiin ngaihtuah la, chu chuan a on leh off a ni. Chumi awmzia chu kan taksaa cell hriselte tihchhiatna a tlem hle tihna a ni.
He damdawi (brand name: GAVRETO) hi cancer chi hrang hrang enkawlna atan hman a ni ber a, a bik takin lung leh thyroid gland-a awmte enkawlna atan hman a ni ber . Cancer zawng zawng tan damdawi a ni lo. I doctor chuan he damdawi hi i tan a tha em tih a rel ang a, chu chu cancer chi hrang hrang i neih dan azirin a ni.
Damdawi i hman hmaa i doctor hnena i hrilh tur thilte
He enkawlna hlawhtlinna tur hian i doctor tan i hriselna dinhmun kimchang a hriat a pawimawh hle. Chuvangin, he damdawi hi i ei tan hmain a hnuaia natna te hi i neih chuan doctor hnenah hrilh hmasa phawt ang che :
- Thisen chhuahna lama harsatna i neih chuan .
- Surgery neih tura ruahman emaw, tun hnaia surgery nei tawh emaw i nih chuan .
- Thisen sang i neih chuan .
- Liver natna i neih chuan .
- Lung natna (e.g. Asthma) emaw, lung natna (scarring/thickening) emaw i neih chuan.
- Naupai i nih chuan, naupai tum i nih chuan, nau hnute i pe a nih chuan .
- He Pralsetinib damdawi emaw, damdawi dang emaw, ei tur emaw, dye dang emaw allergy i neih tawh chuan.
Damdawi hi a dik taka hman tur a ni.
He damdawi hi dik taka hman a nih chuan result tha ber a awm thei a ni.
- He damdawi hi capsule angin a awm a. Tui glass khat nen ei la.
- A pawimawh ber chu hei hi pum ruak chunga ei hi a ni. Chu chu chaw ei hma darkar khat emaw ei zawh hnu darkar hnih tal i ei tur tihna a ni . Chaw ei rualin ei suh.
- He damdawi hi grapefruit tui nen ei loh tur. Damdawi hman tangkai dan a nghawng thei a ni.
- Nitin hun inang deuhah i damdawi ei tum ang che.
- Doctor thurawn tel lo chuan damdawi ei kha bansan suh la, a dose pawh thlak suh.
Damdawi dose khat ka ei loh chuan engtin nge ni ang?
Dose i ei theihnghilh chuan i hriatreng veleh ei nghal rawh. Mahse, i dose tur nen a inhnaih hle a nih chuan (e.g., darkar tlemte chauh a la awm) a nih chuan, dose hloh chu skip la, a hun ruatah dose dang ei leh rawh. Dose pahnih chu a rualin ei ngai suh.
Damdawi ka ei tam lutuk chuan engtin nge ni ang?
I ngaihtuah aia tam damdawi i ei tawh nia i hriat chuan damdawi in pakhata Emergency Treatment Unit (ETU) pan nghal mai tur a ni. A nih loh leh Colombo National Hospital-a National Poisons Information Center-ah biak la, damdawi lam thurawn dil rawh.
Damdawi ei huna fimkhur tur thil bik
He damdawi i ei lai hian i nun chu a hma ang bawkin i chhunzawm thei a, mahse a bik takin i fimkhur tur thil tlemte a awm.
Naupai, nau neih leh hnute pek
Hei hi a pawimawh hle. Naupai laia he damdawi ei hian nausen pum chhunga naute tan harsatna nasa tak a thlen thei a ni.
- Hmeichhia: He damdawi ei lai leh damdawi ei chawlhsan kar 2 chhung chu naupai loh tur a ni. I doctor nen non-hormonal birth control method hman dan tur sawipui rawh.
- Mipa: He damdawi hi i ei lai leh damdawi i ei zawh hnu kar khat chhung chu fa neih loh tur.
- Nau hnute pek: He damdawi hi i ei lai leh i ei zawh hnu kar khat chhung chu naute hnute pek loh tur a ni.
He damdawi hian nau neih theihna a nghawng thei a ni. Hemi chungchangah hian ngaihtuahna i neih chuan i doctor nen inbia ang che.
Operation hma leh operation hnuah
He damdawi hian operation hnua damna a tikhawtlai thei a ni. Chuvangin, operation i neih dawn chuan operation hma ni 5 chhungin damdawi hi i ei tawh loh tur a ni . Operation hnu kar 2 tal i nghah tur a ni a, hliam a dam vek hnuah chauh damdawi ei tan leh tur a ni. I doctor nen inbia la, i hriat chian theih nan.
Hri kai laka invenna
He damdawi hian taksain natna a do theihna (immunity) chu tlem a ti tlem thei a ni. Chuvangin,
- Khawsik leh khawsik ang chi natna nei te lakah inthiarfihlim rawh.
- Khawsik, khawsik emaw, kawr na emaw ang chi symptom i neih chuan mahni indam lo la, doctor hnenah hriattir nghal rawh.
- Doctor thurawn tel lo chuan natna tidamtu aspirin leh ibuprofen te ei loh tur a ni a, hengte hian khawsik a titawp thei a, natna kai hriat a ti harsa thei bawk.
Side effect awm thei te
Damdawi dang ang bawkin he damdawi hian side effect engemaw zat a nei thei. Mahse, mi zawng zawngin an hmu vek lo. Ṭhenkhat chu a nasat em avangin doctor hnenah i hrilh nghal tur a ni. I han en teh ang.
| Side effect chi hrang hrang | Natna |
|---|---|
| Side effects te chu doctor hnenah report nghal tur a ni | |
| Allergic Reaction awm thei te | Vun vun rawng, hnim hring, hmai, hmui emaw lei emaw a hring. |
| Thâwk lak harsat | Thâwk harsa, rilru na, khuh. |
| Thisen chhuahna symptoms a awm | Thinrim dum emaw thisen chhuak emaw, coffee ground ang maia thil luak chhuak, vunah hmun sen, hliam danglam tak, mit, hmui, hnar atanga thisen chhuak. |
| Liver chhiatna chhinchhiahna | Zun dum emaw sen hring emaw, mit emaw vun sen emaw, ei duh lohna, luak chhuak, pum dinglam chunglam na, leh hah lutuk. |
| Symptom na tak dang a awm bawk | Thisen sang sang, lu na, luak chhuak, buai, khawsik. |
| Tumor Lysis Syndrome a awm thei | Luak chhuak, thawk harsa, seizures, muscle na, leh chak lohna. |
| I doctor hnena hrilh tur thilte chu a awm reng emaw, a buaithlak emaw a nih chuan | |
| Side effect awm fo thin | Constipation, luak chhuak, hmui vawt, ruh na, hah. |
He list-a tarlan loh symptom dang danglam tak i neih chuan i doctor nen pawh chutiang lam chu sawipui rawh.
Take-Home Thuchah a ni
- Pralsetinib hi damdawi bik a ni a, cancer cells te chu a target a ni.
- Always take this medicine on an empty stomach. Take it one hour before or two hours after a meal . Grapefruit tui nen ei loh tur.
- Damdawi dang i ei zawng zawng leh i damdawi lam dinhmun zawng zawng chu i doctor hnenah hrilh rawh.
- Damdawi ei lai leh hun bituk chhung chu naupai leh nau hnute pek loh vek tur a ni. Hemi chungchang hi doctor zawt la.
- Thisen chhuah, thawk harsa, vun sen tih ang chi side effect na tak i neih chuan doctor pan nghal rawh.
- Doctor thurawn tel lo chuan damdawi ei kha bansan ngai suh la, a dose pawh thlak ngai suh.
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