I damdawi ei hi nunna atana hlauhawm a ni thei ang em? Serotonin Syndrome chungchang hi han sawi ila

Depression, migraine, a nih loh leh natna nasa tak damdawi ei thin i ni em? A nih loh leh natna pakhat vangin doctor engemaw zat hnen atangin damdawi i ei em? Tichuan he thawnthu hi i tan a pawimawh hle ang. Vawiin hian damdawi chi hrang hrang avanga kan taksaa lo awm thei dinhmun kan sawi dawn a, chu chu hriat chian loh chuan nunna atana hlauhawm thei a ni. Hei hi ‘Serotonin Syndrome’ kan ti a ni. Ngaihtuah buai suh, he thil hi kan hriat chian chuan risk lian tak kan pumpelh thei ang.

A awlsam zawngin, Serotonin Syndrome hi eng nge ni?

Hei hi hrethiam tur chuan ‘Serotonin’ tih hi eng nge a nih kan hriat hmasak a ngai a ni. Kan thluak leh kan taksa peng dang inkara thuchah kengtu palai te tak te angin ngaihtuah teh. Damdawi lamah chuan heng chemical messenger te hi ‘neurotransmitters’ kan ti thin. Serotonin hi kan taksa tana neurotransmitter pawimawh tak a ni bawk a, kan mood, mut leh ei duhna te ang chi thil tam tak a control thei a ni.

A tlangpuiin doctor-in a pek damdawi i ei hian taksaa serotonin level a inthlau hle. Mahse, eng emaw chhan vanga he chemical serotonin an tih hi kan taksaah a pung lutuk a nih chuan , chu chu taksain a tuar theih loh khawpa a punkhawm chuan kan taksain a chunga a thiltih dan chu ‘serotonin syndrome’ an ti a ni. Hei hi damdawi chi khat (drug reaction) avanga thil hlauhawm tak a ni thei.

He natna hi tuin nge vei tam zawk?

Dik tak chuan, kum eng pawha serotonin level tichhe thei damdawi, supplement, emaw, dan loa ruihhlo hmangtu chu a hlauhawm hle. Hetiang dinhmun hi hetiang dinhmunah hian hmuh tur a tam ber a ni:

• Damdawi thar i tan dawnin: Damdawi thar i tan veleh serotonin level tisangtu.
• Damdawi dose tihpun hunah: I doctor-in i ei tawh damdawi dose a tihpun chuan.
• Damdawi engemaw zat hman dun hunah: Hei hi a hlauhawm ber leh a chhan tlangpui a ni. Ngaihtuah teh, i ruh natna (joint ache) i nei a. Chumi atan chuan doctor pakhat hnen atangin painkiller i la thin. Chutih lai chuan i lungkham deuh avangin Doctor dang i hmu a, chumi atan pawh damdawi i ei thin. Mahse, doctor hmasa hnenah damdawi pahnihna chungchang i hrilh lo va, doctor pahnihna hnenah pawh damdawi hmasa ber chungchang i hrilh lo. Hei hi hriat loha serotonin tichaktu damdawi pahnih hman dun a, hetiang dinhmun thlen theihna chance sang tak a awm lai a ni.
• Damdawi i ei tam lutuk chuan: Damdawi pek zat aia tam i ei chuan, tumruh emaw, tihsual emaw a nih chuan.

Eng nge a lan chhuah dan? Engtin nge hei hi kan hriat chian?

Serotonin syndrome symptoms hi mi hrang hrangah a inang lo thei. Mi thenkhat chuan symptoms na lo tak tak an nei thei a, thenkhat erawh chuan symptom na tak, nunna atana hlauhawm tak tak an nei thei thung. Heng symptoms te hi damdawi thar ei emaw, a dose thlak emaw atanga darkar tlemte chhungin a intan tlangpui.

Hriatthiam awlsam zawk nan heng symptoms te hi chi thum ah then ila.

Serotonin level tisangtu damdawi te hi engte nge ni?

He list hi a sei deuh a, mahse i himna atan chuan hei hi hriat a pawimawh hle.

Antidepressant damdawi a ni

Heng damdawi te hi serotonin syndrome nena inzawm tam ber an ni. Hengte hi damdawi dang (e.g., migraine damdawi) nena ei a nih chuan a hlauhawmna a sang hle.

• SSRIs (Selective serotonin reuptake inhibitors): Damdawi chi hrang hrang Fluoxetine, Sertraline, Citalopram, Escitalopram, Paroxetine te hi a ni.
• SNRIs (Serotonin-norepinephrine reuptake inhibitors): Damdawi Venlafaxine, Duloxetine, Desvenlafaxine te ang chi te.
• Tricyclic antidepressants: Damdawi chi hrang hrang Amitriptyline, Nortriptyline, Imipramine te hi a ni.
• MAOIs (Monoamine oxidase inhibitors): Hengte hi hman tlanglawn tawh lo mah se, a then phei chuan pek thin a ni.

Damdawi dang

• Natna nasa tak damdawi: Natna tidamtu Tramadol, Pethidine (Meperidine), Fentanyl, leh Methadone te ang chi.
• Khuh damdawi: Damdawi dawr atanga khuh damdawi thenkhatah hian Dextromethorphan tih hming pu thil a awm a. Hei hian serotonin level a nghawng thei bawk.
• Migraine damdawi: Triptan damdawi Sumatriptan leh Rizatriptan te.
• Luak chhuak damdawi: Metoclopramide leh Ondansetron ang chi damdawi.
• Antibiotics thenkhat: Antibiotic linezolid.
• Mood control damdawi: Lithium.

Thil dang

• Herbal supplement: St. John’s wort leh Ginseng ang chi thil te.
• Dan loa ruihhlo: Ecstasy (MDMA), LSD, Cocaine, Amphetamines ang chi thil.

He list hian hlauthawng suh. Heng damdawi pakhat ei hnuah hian mi zawng zawngin he natna hi an nei vek dawn lo. Heng zinga engemaw zat i hman dun emaw, i tihpun emaw, i taksain a sensitive emaw chauhvin risk hi a lo awm thin.

Engtin nge doctor hian hei hi a hriat theih?

Serotonin syndrome finfiah nan thisen test leh scan bik a awm lo. Doctor chuan thil engemaw zat a zirin a natna hi a hriat theih ang:

1. I natna lan chhuah dan: I thil hriatte ngun takin ngaithla rawh.

2. Taksa enfiahna: I heart rate, thisen sang, taksa lum leh thau leh thau dinhmun te enfiah a ni ang.

3. Damdawi i ei tur list: Hei hi a pawimawh ber a ni.

Chu bakah, thisen leh zun test te, chest X-ray te, CT scan te pawh i nei thei bawk a, chu chuan natna dang (e.g., infection) i neih loh nan, chutiang bawka natna lan chhuah dan chu i nei lo tih i hriat chian theih nan.

Hei hi eng enkawlna nge ni?

Enkawlna chu i natna lan chhuah dan nasat danah a innghat.

• Symptoms na lo tak tak i neih chuan: Enkawl dan tlangpui chu a natna thlentu damdawi ei kha bansan hi a ni. Hei hian a tlangpuiin darkar 24-72 chhungin a natna lanchhuahna chu a reh vek ang.
• Symptoms hniam tak i neih chuan: Damdawi inah dahin darkar 24 tal enkawl i ni ang. Hemi chhung hian saline (IV fluids) leh lungkhamna atana damdawi benzodiazepines te pek i ni ang.
• Symptoms na tak i neih chuan: Hei hi medical emergency a ni. Intensive care unit (ICU)-ah dah i ni ang a, thawk harsatna te tanpui, khawsik sang control, leh heart rate leh blood pressure control na tur damdawi te pek i ni ang. A châng chuan, serotonin hnathawh tikhawlotu Cyproheptadine an tih damdawi pawh pek theih a ni.

Hetiang dinhmun lakah hian engtin nge kan inven theih ang?

He dinhmun hlauhawm tak laka kan him theih nan thil awlsam tak tak, mahse pawimawh tak tak tlemte kan tih theih a awm.

1. I damdawi ei dan chungchangah inzirtir rawh: Damdawi i ei apiang hming, a hman dan leh a tum zawng zawng ziak vek ang che.

2. Doctor tinte hnenah a chipchiar zawng hrilh rawh: Doctor engemaw zatin an enkawl che a nih chuan doctor pakhat hnenah midangte’n damdawi an pekte chu hrilh ngei ngei tur a ni.

3. Doctor zawt lovin damdawi ei khap suh: Harsatna i nei a nih pawhin Doctor biak lovin damdawi ei kha bansan suh emaw, a dose pawh thlak danglam suh.

4. Damdawi dawr atanga damdawi i lei dawnin fimkhur rawh: Khuh leh khawsik ang chi thil atana damdawi i lei dawnin i damdawi ei tawh nen a inmil tur damdawi dil thin ang che.

5. Symptoms ngaihven: I taksaa inthlak danglamna eng pawh hi ngun takin ngaihven la, a bik takin damdawi thar i tan emaw, a dose tihpun emaw hian ngaihven rawh.