I Gut leh Brain Inkâra Thuruk (Gut-Brain Connection) - Hemi chungchang hi i sawi dawn nia!

"Gut talk" tih hi i hre tawh em? A nih loh leh thil tha tak a thlen dawn lai hian "i pum chhungah hnim hring" i nei ang tih i hria em? Chutiang bawkin thil harsa tak a thlen chuan "i pum hian a chhuahsan dawn che" i ti thin. Heng zawng zawng hi a takah chuan kan thluak leh kan gut, a nih loh leh digestive system inzawmna mak tak avang a ni. Heng pahnih hi an inbia reng a ni.

Engvangin nge gut leh thluak inkarah hian inzawmna nghet tak a awm?

Hetiang hian han ngaihtuah teh: kan thluak leh kan gut chu ṭhian ṭha ber ang mai a ni . An inbia reng a. Kan ei leh in chungchang chauh ni lovin, kan hlimna te, lungngaihna te, hlauhna te pawh an inthleng thin. Dik tak chuan kan taksa chhunga system dang zawng zawng aiin kan thluak leh kan gut inkarah hian information a inthleng tam zawk a ni. Chu chu thil mak a ni lo’m ni? Kan gut, a nih loh leh digestive system hi thluak pawn lama nerve cell awm tam ber niin an sawi.

Chuti a nih chuan, engvangin nge heng pahnih inkarah hian inzawmna lian tak a awm? A awlsam zawngin kan dam khawchhuahna tura duan a ni. Kan chaw ei hi kan taksa pum pui tan a pawimawh zia i hria. Hmanlai atang tawhin miten ei tur chi hrang hrang an nei tawh a. Chuvangin, kan taksa hian ei tur dik tak a dawng tih chian nan, thil dik lo kan ei lai hriat thuai nan emaw, hun engemaw chen chu chaw ei khama tihtawp nan emaw ``alarm system`` tha tak a mamawh a ni.

He "bell system" hian kan thluak chhunga emotion control tu part pawh a huam tel bawk. Ngaihtuah teh, thil tha lo i chunga a lo thlen hian a thleng leh tawh loh nan i rilruah hriatrengna a dahkhawm thin. Chutiang bawkin, emotion hian kan gut sensation a ti na zual thei bawk. Tin, gut sensations chak tak hian kan stress leh emotional response a tipung thei bawk. Back-and-forth cycle ang mai a ni a, a bik takin thluak leh gut inkarah a ni.

He inzawmna hian kan taksaah eng ang thil nge a nghawng?

Tunah chuan he gut-brain inbiakna hian kan taksaah eng ang thil nge a nghawng tih hi han en ila. Research atanga a lan dan chuan he inzawmna hian a hnuaia mite hi a nghawng a ni:

• Riltam leh satiety
• Chaw duhzawng leh duhzawng
• Chaw ei tur sensitivity leh intolerance te
• Gut motility a awm thei
• Chaw ei dan (digestion) a ni
• Thilsiam (metabolism) a awm
• Ngaihtuahna
• Nungchang
• Stress level a sang hle
• Natna hriat theihna
• Ngaihtuah thiamna leh ngaihvenna (`Cognitive function`) ang chi thil .
• Immunity a ni

He gut-brain inzawmnaah hian eng system nge inrawlh?

Doctor-te chuan he gut-brain connection chungchang hi an sawi hian ``Gut-Brain Axis`` an ti thin.Thluak leh gut inzawmkhawmtu nerve network ang mai a ni a, thuchah a keng chhuak leh chhuak thin. Mahse, he nervous system hian amah chauhin hna a thawk lo. Kan endocrine system, hormone siamtu (heng hormone te hian riltam, puar, leh stress ang chi thil min hrilh) leh kan immune system (gut-a natna hrik emaw hliam emaw eng pawh awm se a dik taka chhangtu) nen pawh a thawk dun hle.

He network chhungah hian gut-brain connection-a hmun pawimawh tak changtu mi engemaw zat an awm a:

Thluak chhunga thluak tlemte - Enteric Nervous System (ENS) .

Kan chaw ei dan (`Gastrointestinal (GI) tract`) chhungah hian a chaw ei dan (digestive functions) control tu nervous system hran a awm tih i hria em. Chu chu `Enteric Nervous System` (`ENS`) tih a ni. Nerve cell maktaduai 500 chuang a nei a ni! Chumi awmzia chu, hei hi kan thluak pawn lama nervous system complex ber a ni tihna a ni. Hei hi a danglamna dang chu kan thluak leh main central nervous system (`central nervous system`) atanga innghat lovin hna a thawk thei a ni. Hemi avang hian scientist thenkhat chuan ``second brain`` an ti bawk.

ENS hi a takah chuan kan chhungril taksa peng hrang hrangte duh loh zawnga thiltih control tu autonomic nervous system-a thil bik a ni. Autonomic nervous system pumpuiah a thawh laiin, mahni inrintawkna neiin a thawk bawk. Chu chu, gut chhunga thil awm dan chungchang information a khawlkhawm thei a, chu information chu chutah chuan a process thei a, thluaka thawn lovin a chhang let thei tihna a ni.

Inbiakpawhna kawngpui ber - Vagus Nerve

Gut chhunga nervous system (ENS) leh kan thluak inzawmna ber chu vagus nerve a ni. Hei hi kan luruh (cranium) atanga intan, taksa hnuai lam pan a, kawngpuiah branch chhuak thin cranial nerve 12 zinga pakhat a ni. Vagus nerve hian ENS atanga thluak thlengin gut chhunga thil awm dan chungchangah sensory information a keng tel a ni. Chumi chhanna atan chuan he nerve vek hian thluak atanga gut thlengin motor signal a phur a ni.

Gut chhunga thil awmdan a inthlak danglam a, entirnan, chemical inthlak danglam emaw, ei tur lo thleng emaw a nih chuan, a chhanna atan gut chhungah hian reflexes hrang hrang a awm a. Chungte chu vagal reflexes an ti a. Chung zinga ṭhenkhat chu thluak (intrinsic vagal reflexes) tel lovin ENS chhungah an thawk chhuak a ni. Mi dangte chu ENS leh central nervous system (extrinsic reflexes) inkara inbiakpawhna hmangin an thawk chhuak thin.

Kan gut chhunga ṭhian te te - gut microbiome te

Hei hi i tan chuan mak tih tur a ni mai thei. Kan gut chhunga awm bacteria te pawh hi he gut-brain connection ah hian an tel ve bawk! Ni e, heng gut microbes te hiGut leh thluak inkara thuchah kengtu chemical messenger (`neurotransmitters`) tam tak siamtu emaw, siam chhuah puitu emaw an ni. Chu mai ni lovin, kan thisen kaltlanga thluak nghawng thei chemical dang an siam chhuak bawk. A lehlamah kan thluak leh kan gut hian heng microbes te chenna boruak hi a tidanglam thei a, an khawtlang (the `gut microbiome`) a nghawng thei a ni.

Tun hnaia zirchianna hrang hrangah chuan he gut microbes inzawmkhawm hi thluak lam natna hrang hrang, rilru lam harsatna, leh functional gastrointestinal disorders te nen a inzawm thei tih hmuhchhuah a ni.

Heng functional disorders te hi symptoms awm reng mahse taksa lama chhan chiang tak hmuh theih lohna condition an ni. Entirnan, irritable bowel syndrome (IBS) vei leh rilru lam harsatna nei, lungkhamna nei te inkarah hian inzawmna lian tak a awm a.

Eng natna nge gut-brain axis nena inzawm theih?

Chuti a nih chuan, he gut-brain axis hian hna a thawk tha lo a nih chuan, a nih loh leh thil dik lo a awm a nih chuan, eng ang natna emaw, symptom emaw nge lo awm thei? He list hi en la:

• Irritable Bowel Syndrome (IBS) leh functional constipation emaw riltam emaw a awm thei
• Rilru natna, lungkhamna leh lungngaihna te
• Noncardiac rilru natna
• Nausen colic a awm
• Functional dyspepsia a awm thin
• Functional dysphagia a awm thin
• Pum chhunga thau tha lo (Gastroparesis) .
• Anus muscle lama harsatna (`Anismus`) .
• Stress rei tak awm thei
• Chauhna rei tak a awm
• Natna rei tak a awm
• Visceral hypersensitivity a awm bawk
• Thau lutuk
• Neurodevelopmental disorder, autism ang chi te pawh a awm thei
• Neurodegenerative disorder, Parkinson natna ang chi te
• Nerve nena inzawm natna chi hrang hrang, multiple sclerosis ang chi te

Hetiang dinhmun hi doctor-te hian engtin nge an enkawl?

Doctor-te chuan engtin nge gut leh thluak pahnih inzawm nia lang dinhmunte chu an enkawl? Dik tak chuan tunah chuan doctor-te chuan heng natnate enkawl hian i gut chhunga microbes (the ``gut microbiome``) te chu an en tan ta a ni.

Gut microbes enkawl dan tur

Rannung zirchianna atanga a lan dan chuan gut chhunga microbes (`microbiota`) hrisel, chi hrang hrang awmna hian gastrointestinal, neurological, inflammatory, leh psychological disorders symptoms a tihziaawm thei a ni. Hei hian mihringah engtin nge hna a thawh theih ang tih chungchangah result a la inang lo hle a, mahse ngaihnawm tak a ni. Heng gut microbes te hi enkawl dan tur thenkhat chu hetiang hi a ni:

• Probiotics : Hengte hi yogurt leh fermented foods ang chi thila awm bacteria tha tak takte an ni.
• Antibiotics : A chang chuan bacteria tha lo a that thin.
• Fecal microbiota transplantation (FMT) : Hei hi hmanraw thar tak a ni. Mi hrisel ek atanga bacteria tha tak tak, damlo intestine-a luhtir a ni.

Rilru leh taksa therapy

Tin, functional gastrointestinal disorder thenkhat nei te chuan behavioral medicine specialist te nen mind-body therapy hmangin hlawkna an hmu thei bawk. Heng therapies te hian gastrointestinal symptoms awm reng chu a tihziaawm thei a, a tlem berah chuan chu chu hmachhawn dan zir turin a pui thei bawk. I mood leh stress pum pui tihziaawmna turin an pui thei bawk. Hei hi indirect takin i gut tan a tha thei. Heng therapies thenkhat hi chu:

• Relaxation therapy : Hei hian i rilru hahdam theihna tur leh i natural stress response tihziaawmna tur technique hrang hrang hman a huam a ni. Entîr nân, taksa ruhte tih hahdamna, mit hmuh theihna, leh music tihrehawmna. Research atanga a lan dan chuan heng technique te hi cognitive behavioral therapy (CBT) nena hman dun a nih chuan a hlawk ber a ni.
• Cognitive Behavioral Therapy (CBT) : He therapy hian a tum ber chu chaw kawng lama harsatna nei te chu taksa natna avanga an ngaihtuahna, nungchang leh rilru lama an chhanna te, chubakah rilru/rilru lama harsatna leh lungkhamna te tihdanglam a ni.
• Gut-directed relaxation training : Hei hi deep relaxation a ni a, gastrointestinal function chungchanga rawtna tha tak tak nen a inzawm a ni. Entirnan, i pum chunga kut dah te, lumna hriatna te, leh i ril i thunun thei ang tih ngaihtuah te. Hetiang hmanrua hi stress langsar tak nei lo symptom nei tan chuan a \angkai thei hle.
• Biofeedback a ni: He enkawlna hian mi chu an taksa pianphung chhanna (natural response) thunun dan a zirtir a ni. Entîr nân, electronic hmanrua hmanga i thinlung thawk emaw, i taksa lumna emaw control zir. Research atanga a lan dan chuan biofeedback hi stress leh symptom management technique dangte nen a inzawm chuan active gastrointestinal diseases nei te tan hriselna lamah result tha tak a siam thin.

He gut-brain connection hi in lama awm reng turin eng nge kan tih theih ang?

Chuti a nih chuan, he gut-brain axis pawimawh ber hi vawng reng turin in lamah eng nge kan tih theih ang?

Nitin i gut hriselna enkawl dan tha ber – leh a rah chhuah i thluak hriselna enkawl dan tha ber chu ei leh in hrisel, inthlau tak ei hi a ni . I thluak hriselna enkawl dan dang – leh i gut hriselna pawh a ni mai thei – i stress hi i theih ang anga enkawl hi a ni. Stress hunlaia stress control dan tur i ngaihtuah thei bawk a, chubakah nitin nunah stress tihziaawm dan tur pawh i ngaihtuah thei bawk.

Hemi atan hian eng ang ei leh in nge tha?

Natural taka i gut health tihchangtlunna atana dan tha tak chu whole foods chi hrang hrang ei hi a ni a , a bik takin thei leh thlai chi hrang hrang ei hi a ni I ei leh in hrang hrang a tam poh leh i gut microbiome pawh a chi hrang hrang ang. Chu chu i gut health pum pui atan a tha hle. Whole foods leh plant te hian processed foods aiin calorie khatah nutrition an nei tam zawk. Chu chu additive hrisel lo, sweeteners leh saturated fats te awmna tur hmun a tlem tihna a ni. Chu ai chuan hetiang hi kan hmu zawk thin:

• Soluble leh insoluble fiber : Thlai tam takah hian fiber chi hnih a awm a. Hengte hian kan riltamna a tidanglam a, kan gut chhunga microbes (microbiota) \angkai tak takte ei tur a pe bawk. Heng microbes te hian kan intestine lining chu an chawm ve bawk.
• Prebiotics leh probiotics : Probiotics hi bacteria nung a ni a, ei tur fermented yogurt leh sauerkraut-ah te a awm a. Prebiotics hi heng bacteria te hian an ei duh fiber leh complex starch chi hrang hrang an ni.
• Antioxidants : Heng antioxidants te hi thei leh thlai chi hrang hranga pianphung anga awm te hian kan taksaa free radicals te dona kawngah a pui a, inflammation a veng bawk. Chaw chi hrang hrangah hian antioxidant chi hrang hrang a awm a.
• Anti-inflammatory ei tur te: Chaw pum pui, thing leh mau atanga siam ei hian a pianphungah inflammation a tihziaawm a, a chhan chu sugar, additives leh cholesterol a tlem avangin. Hei hian kan gut chhunga microbes te chu hlim taka awm tir turin a pui thin.

A tawi zawngin, eng nge hriat reng tur

I gut leh thluak hi ṭhian hnai tak pahnih ang mai a ni a, nerve leh chemical signal hmangin an inbiak reng a ni. An inhnaih em avangin pakhat zel hrehawmna chu an hre thei a ni. I chaw ei dan emaw, i nervous system emaw tichhe thei natna i neih chuan system dang pawh a inrawlh a rinawm. Tunah chuan doctor-te chuan heng dinhmunte hi gut-brain axis sir lehlamah an en thin. Chutiang bawk chuan i rilru hriselna bakah i gut hriselna pawh i enkawl thei bawk. A chhan chu an pahnih hi an inzawm tlat a ni!

` Gut-brain connection, chaw ei dan, rilru hriselna, nervous system, microbiome, ei leh in, stress