Kum 25 chhung zet lungngaihna nasa tak tuar tawh tu emaw han mitthla teh. Damdawi leh enkawlna awm zawng zawng an lo enchhin tawh a, mahse hahdamna a awm lo. Nunna a chau tawh a, tanpui theih loh khawpin sofa atang pawha tho thei lo an ni. Damdawi pakhat ‘Ketamine’ tih hian nun thar a pe tih ka hrilh che chuan min ring ang em? Hei hi mi thenkhat chunga thil thleng tak tak a ni. Mahse hlawhtlinna chanchin zawng zawng hnuaiah hian he damdawi hman dik loh avanga nunna chan tawhte chanchin kan hre bawk. Chuti a nih chuan, Ketamine hi eng nge ni tak tak? Depression ang chi rilru natnaah a pui em? Risk hi a phu em? Hemi chungchang hi awlsam tak leh chiang takin sawi ila.
Ketamine hi eng nge ni?
A awlsam zawngin Ketamine hi a takah chuan anesthetic a ni. Chu chu mutthilhtirtu damdawi tihna a ni. He damdawi hi kum 1960 chho vela rannung anesthetize nana hman hmasak ber a ni a, kum 1970 khan US FDA chuan mihringah hman a phalsak a, Vietnam War-a sipai hliamte enkawlna atan pawh hman a ni.
Entirnan, emergency-ah chuan mahni intihhlum tum mi pakhat chhanchhuah a nih hnuah, an buaina thunun nan he damdawi hi ambulance-ah pek a ni fo thin. Hetiang thil thleng avang hian doctor-te chuan depression laka a thiltihtheihna chu an hrethiam tan ta a ni. Ngaihtuah teh, bridge atanga zuang chhuak tur mi pakhat hnenah Ketamine a pek hnuah thla 9 vel hnuah, "Thla 9 chhung zet chu mahni intihhlum ka ngaihtuah lo," a ti a. Hetiang thawnthu hi a tam chhoh zel avangin doctor-te chuan, "Hei hi thil a awm mai thei," tiin an ngaihtuah a.
Mahse hei hi a thim lam a awm. Ketamine hi damdawi pakhat a ni a, mi thenkhat chuan an sang chho zel a. Mi thenkhat chuan ‘Special K’, ‘Super K’ an ti thin. Inject a ni a, in turah te dah a ni a, cigarette-ah te hman a ni.
Ketamine hian hun engemaw chen chu hmun dangah awm lo anga inhriatna, mit leh hriatna dik lo, i taksa chungchanga hriatna mak tak tak, ngaihtuahna danglam tak, leh euphoria te a thlen thei a ni. Doctor-te chuan hei hi ‘dissociative experience’ an ti.
He thil tawn hi darkar hnih vel a ni. Damdawi lam enkawlna hnuaiah chauh lak tur a ni. Hei hi a chhan chu thil hlauhawm tak tak a keng tel a, chu chu hriatna hloh, thisen sang, leh thawk hah lutuk te hi a ni. A hman dik loh chuan hun rei tak chhung harsatna, bladder lama harsatna leh ruihhlo ngawlvei te a thlen thei a ni.
Engtin nge Ketamine enkawlna ka hmuh theih ang?
Tunah hian FDA-in a pawmpui depression enkawlna awmchhun chu ketamine hmanga siam nasal spray Esketamine tih a ni. Certified clinic-ah chauh pek a ni a, treatment-resistant major depressive disorder nei, antidepressant dang pahnih tal ei lote tan chauh pek a ni. Damlo chu spray pek a nih hnuah darkar hnih chhung medical staff ten an vil reng a ni.
Thil dang, intravenous (IV) Ketamine te hi rilru lam enkawlna atan FDA-in a la pawm lo. Mahse, doctor-te chuan he method hi medical supervision hnuaiah, research data atanga chhutin, damdawi dang ei lote tan an hmang mek a ni.
- Enkawlna: Damlote hi kar thum chhungin IV infusion vawi ruk pek an ni tlangpui.
- Dosage: Dosage hi chiang takin a hriat a ngai a, a chhan chu depression tan chuan a tangkai hle a, mahse anesthesia tan erawh a tangkai lo dose a tlem hle.
- Supervision: IV pek chhung minute 40 chhung zawng leh a hnu lamah doctor a awm ang. Damloin harsatna emaw, buaina emaw a neih chuan tanpui nghal turin an inpeih reng ang.
Enkawl lai hian engtin nge a awm?
Hetiang enkawlna dawng tawhte hian an thil tawn chu kawng hrang hrangin an sawi a. Hmeichhe pakhat Krista tih hming pu, a naupan lai atanga lungngaihna leh lungkhamna nei tawh chuan a hnuah PTSD leh natna rei tak a nei ta a ni. Ketamine enkawl hma khan heng natnate hian a nun a thunun tih a sawi.
"Enkawlna ka neih chhung hian thlarau lam zinkawng zawh mek ang maiin ka inhria. Ka lum a, ka him a, ka inrintawk hle bawk. Ka rilru a rit zawng zawng chu layer khat hnu layer khata lak chhuah vek ang maiin ka hria. Ka kutphah bulah universe thiltihtheihna ka nei niin ka hria.
A hmaa kan biak tawh Jeff-a chuan a thil tawn chu hetiang hian a sawi a, "Tui tuikhuah chhunga tui pil ang mai a ni. Chu chu 'hmun hlim' tih thumal awmzia ka hriatthiam hmasak ber a ni. Ka nun tak tak nena inzawm zawng zawng chu a bo vek a, chutiang rit phurh chu hmun tina ka phur kual vel chu ka hre lo," a ti.
Enkawlna an neih zawh chuan Ketamine-in nghawng a neih a reh deuh deuh chuan clinic thenkhatah chuan damlo nen inbiakna an nei bawk a, chu chuan an thil tawn atanga an thil zir te chu an nunah an inzawm khawm theih nan an pui thin. Hei hian damlo chu thil hlui leh hrehawmna chungchang sawi theihna hun remchang a pe a ni.
Ketamine hian engtin nge thluak a nghawng?
Mak tak mai chu, enkawlna chhunga i tawn thin ‘dissociative experience’ hian depression atanga hahdamna a thlen lo. Chu hahdamna chu a hnuah a lo thleng thin. Chu chu Ketamine i ei hnua i thluak a chhan dan chu a enkawlna a ni tihna a ni.
Hetiang hian ngaihtuah mai rawh:
Hun rei tak, lungngaihna nasa tak nei tawhteah chuan thluaka nerve cell inkara thuchah thawn chhuaktu inzawmna pawimawh tak tak (synapses) thenkhat chu a bo vek a ni. Research atanga a lan dan chuan ketamine dose hmasa ber atanga darkar 24 chhungin heng connection hloh te hi a lo thang leh tan thin. Heng inzawmnate hi a lo thang lian poh leh lungngaihna atanga chhanchhuahna a nasa zawk thin.
Phên dangin sawi ila, kan thluaka kan rilru put hmang (mod)-a inrawlh nerve cell-te hian chemical ``glutamate`` an tih chu an inbiakpawhna atan an hmang a ni. Depression nei thenkhat chuan an thluaka ``glutamate`` chhanna receptor chak lo tak tak an nei a.Ketamine hian heng receptor te hi siam thar lehin nerve cell te inbiakpawhna tha tak siam leh turin a pui thin.
Chutianga thluak inzawmna siam that a nih chuan antidepressant emaw, a hmaa thawk lo psychotherapy emaw pawhin hna a thawk tan thei a ni.
A side effect leh risk te chu engte nge ni?
Damdawi lam enkawlna hnuaia hman a nih pawhin Ketamine hian side effect a nei thei a ni.
| Side effect chi hrang hrang | Hrilhfiahna |
|---|---|
| Hun rei lote chhunga nghawng tha lo (enkawl lai) . | Mutthilh, luak chhuak, thisen sang tlem a sang, luak chhuak, leh ‘dissociative experiences’ (thil mak/ tak tak ni lo anga inhriatna). |
| Hun rei tak chhunga nghawng tha lo (hman dik loh leh hman tam lutuk atanga) . |
|
Addiction awm theihna risk
Ni e, Ketamine hi ruihhlo ngawlvei thei tak a ni. Mahse doctor-te chuan medical supervision mumal tak hnuaia enkawl leh protocol dik tak anga enkawl a nih chuan addiction hlauhawmna a tlem hle niin an sawi. A hlauhawmna chu mi pakhatin damdawi lam thurawn tel lova mahni thil tum atana a hman tan hian a ni.
Pawimawh tak: Nangmah emaw i hriat emaw chuan Ketamine emaw damdawi dang emaw nena inzawm emergency a neih chuan damdawi in hnai ber Emergency Department (ETU) ah kal nghal rawh. Poisoning chungchanga thurawn i mamawh chuan Colombo National Hospital-a National Poisons Information Center ah call rawh .
Hei hi tu tan nge a inhmeh lo?
Ruihhlo hmansual tawh leh rilru lam natna, schizophrenia ang chi nei tawhte tan chuan ketamine enkawlna hi a tha lo mai thei. Bipolar disorder nei te pawhin fimkhur hle tur a ni a, Ketamine hian manic episode a thlen tam lo hle. Hei hi i doctor-in a rel tur a ni.
Take-Home Thuchah a ni
- Ketamine hi antidepressant hman tlanglawn tak a ni lo. Damdawi chak tak, anesthetic damdawi a ni.
- He enkawlna hi damdawi dang laka chhanna nei lo, lungngaihna nasa tak ang chi, damdawi lam enkawlna khauh tak hnuaiah chauh hman tur a ni.
- Ketamine hi intihhlimna emaw intihhlimna atana hman hi a hlauhawm hle. Ruihhlo ngawlvei, taksa leh rilru natna na tak, thihna thlengin a thlen thei a ni.
- Tunah hian Esketamine (a nasal spray) hi FDA-in a pawmpui awmchhun a ni a, certified clinic-ah chauh pek a ni.
- Nangmah emaw i hriat mi emaw chu lungngaihna nasa tak i vei a nih chuan Ketamine enkawlna chungchangah hian nangmah chauhin thutlukna siam suh la, mahse hei hi i doctor nen rei tak sawipui la , a thatna leh that lohna zawng zawng hrethiam rawh.
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