Kodi munayamba mwadzifunsapo momwe thupi lanu limasungira shuga m'magazi mwanu moyenera? Chinthu chofunikira kwambiri pankhaniyi ndi chinthu chotchedwa glucagon. Ganizirani izi ngati ngwazi yaying'ono m'thupi lanu, yogwira ntchito mosatopa kuti shuga m'magazi mwanu isatsike kwambiri. Lero, tifufuza momwe glucagon imagwirira ntchito, momveka bwino komanso mosavuta, kuno ku Nirogi Lanka.
Kodi Glucagon ndi chiyani?
Mwachidule, glucagon ndi mahomoni achilengedwe opangidwa ndi thupi lanu . Makamaka, amapangidwa ndi maselo a alpha omwe ali mu kapamba wanu. Thupi lanu limatulutsa glucagon nthawi iliyonse yomwe shuga m'magazi mwanu imatsika - monga nthawi yosala kudya kwa nthawi yayitali, kuchita masewera olimbitsa thupi kwambiri, kapena mutadya chakudya chokhala ndi mapuloteni ambiri.
Ganizirani za shuga ngati gwero lalikulu la mafuta m'thupi lanu, lomwe mumapeza kuchokera ku chakudya chomwe mumadya. Monga petulo wa galimoto, shuga uyu amapereka mphamvu zofunika kuti ziwalo zanu, minofu, ndi mitsempha zigwire ntchito. Thupi lanu limasunga bwino komanso lolimba kuti shuga uyu akhale wathanzi; ngati akwera kwambiri kapena otsika kwambiri, zingayambitse mavuto osiyanasiyana azaumoyo.
Majakisoni a Glucagon ndi Ma Spray a Mphuno
Kuwonjezera pa glucagon yomwe thupi lanu limapanga, palinso mitundu yopangidwa ngati jakisoni kapena mankhwala opopera m'mphuno. Mwina mwawonapo izi zikugwiritsidwa ntchito, makamaka ndi anthu omwe ali ndi matenda a shuga a Mtundu 1 , ngati chithandizo chadzidzidzi cha hypoglycemia yayikulu (shuga wochepa kwambiri m'magazi). Ikaperekedwa, glucagon iyi imagwira ntchito polimbikitsa chiwindi chanu kutulutsa shuga wosungidwa m'magazi anu, zomwe zimathandiza kuti shuga wanu ukhale wochuluka komanso wotetezeka.
Kodi Glucagon Imakhudza Bwanji Thupi Lanu?
Pamene kapamba wanu akugwira ntchito bwino, amawongolera shuga m'magazi mwanu mosamala pogwiritsa ntchito mahomoni awiri akuluakulu: glucagon ndi insulin . Pamene shuga m'magazi mwanu ayamba kutsika kwambiri (hypoglycemia), kapamba wanu amatulutsa glucagon yambiri kuti abweretse shuga m'magazi kudzera m'njira zingapo:
- Choyamba, glucagon imapita ku chiwindi chanu ndipo imasintha shuga wosungidwa—wotchedwa glycogen —kukhala mtundu wogwiritsidwa ntchito, womwe chiwindi chimautulutsa m'magazi anu.
- Chachiwiri, glucagon imauza chiwindi chanu kuti chisiye kusunga shuga, zomwe zimapangitsa kuti shuga wambiri ukhalebe m'magazi anu.
- Chachitatu, glucagon imathandiza thupi lanu kupanga shuga watsopano kuchokera kuzinthu zina, monga ma amino acid .
Kumbukirani, izi zili ngati seesaw: shuga ikachepa m'magazi, glucagon imagwira ntchito; shuga ikachuluka m'magazi, insulin imayamba kugwira ntchito!
Kodi ndi zinthu ziti zomwe zimakhudza ntchito ya Glucagon?
Ngati thupi lanu likuvutika kugwiritsa ntchito bwino glucagon, izi zingayambitse mavuto azaumoyo.
Ngati muli ndi matenda a shuga, thupi lanu lingavutike kutulutsa glucagon wokwanira shuga ikatsika m'magazi. Izi zimakuikani pamavutochiopsezo chachikulu cha hypoglycemia yobwerezabwereza kapena yoopsa, makamaka ngati mukumwa insulin kapena mankhwala ena monga sulfonylureas.
Kwa anthu ena omwe ali ndi matenda a shuga a mtundu wa 2, kuchuluka kwa glucagon kumatha kukhala kokwera kuposa masiku onse, zomwe zingapangitse kuti shuga m'magazi akwere.
Ngakhale mavuto okhudzana ndi kupanga glucagon kunja kwa matenda a shuga ndi osowa, amatha kuchitika chifukwa cha:
- Pancreatitis: Ngati kutupa kosatha kwa kapamba kumayambitsa matenda a shuga, mungakumane ndi vuto la kusowa kwa glucagon, zomwe zimawonjezera chiopsezo chanu chokhala ndi shuga wotsika m'magazi.
- Glucagonoma: Chotupa chosowa kwambiri cha kapamba chomwe chimapanga glucagon wochuluka, zomwe zimapangitsa kuti shuga m'magazi achuluke, ziphuphu zinazake pakhungu, komanso kuchepa thupi.
- Multiple Endocrine Neoplasia (MEN): Matenda osowa kwambiri a majini pomwe ma glands angapo mu dongosolo lanu la endocrine amakula ndi zotupa, zomwe zingaphatikizepo kapamba.
- Pancreatectomy: Ngati gawo lina kapena lonse la kapamba wanu lachotsedwa opaleshoni, mutha kutaya maselo omwe amapanga glucagon ndi insulin.
Zizindikiro za Mavuto Okhudzana ndi Glucagon
Monga tafotokozera, kusakhazikika kwa glucagon kungayambitse hypoglycemia (shuga wochepa m'magazi) kapena hyperglycemia (shuga wokwera m'magazi). Umu ndi momwe mungadziwire zizindikiro izi.
Zizindikiro za Hypoglycemia (Shuga Wochepa M'magazi)
Ngati inu kapena wokondedwa wanu muli ndi matenda a shuga, ndikofunikira kuzindikira zizindikiro za kuchepa kwa shuga m'magazi. Mungamve mwadzidzidzi mukunjenjemera, kutuluka thukuta, kapena chizungulire, komanso kukhala ndi vuto lolankhula kapena kukhazikika. Ichi chikhoza kukhala chizindikiro cha shuga wotsika m'magazi.
Zizindikiro zodziwika bwino ndi izi:
- Kugwedezeka kapena kugwedezeka
- Kutuluka thukuta komanso kumva kuzizira
- Chizungulire kapena mutu wopepuka
- Kugunda kwa mtima mwachangu
- Njala yadzidzidzi
- Kusokonezeka kapena kuvutika kuyang'ana kwambiri
Chofunika: Ngati mukukumana ndi zizindikiro izi, ndikofunikira kuti mudye chakudya chokhala ndi shuga kapena chakudya nthawi yomweyo . Izi zimathandiza kubwezeretsa shuga m'magazi mwanu. Ngati izi zikuchitika pafupipafupi, muyenera kufunsa dokotala wanu nthawi yomweyo.
Zizindikiro za shuga wambiri m'magazi (hyperglycemia)
Kuchuluka kwa shuga m'magazi (hyperglycemia) nthawi zambiri kumachitika chifukwa cha kusowa kwa insulin, osati vuto lalikulu la glucagon. Komabe, mavuto osowa okhudzana ndi glucagon angayambitsenso kuchuluka kwa shuga m'magazi. Zizindikiro zoyambirira ndi izi:
- Kuwonjezeka kwa ludzu ndi/kapena njala yosalekeza
- Maso osawoneka bwino
- Kukodza pafupipafupi
- Mutu
Ngati mukukumana ndi zizindikiro izi, ndikofunikira kwambiri kuonana ndi katswiri wazachipatala.
Ndi mayeso ati omwe amagwiritsidwa ntchito poyesa kuchuluka kwa glucagon?
Ngati mukuwonetsa zizindikiro zina, dokotala wanu angakupatseni mayeso a magazi kuti awone kuchuluka kwa glucagon m'magazi anu. Pa nthawiyi, dokotala kapena namwino adzatenga magazi kuchokera m'mitsempha pogwiritsa ntchito singano, kenako n’kutumizidwa ku labotale kuti akawunikidwe.
Kodi milingo ya Glucagon ndi yotani?
Kawirikawiri, kuchuluka kwa glucagon m'magazi anu kumakhala pakati pa ma picogram 50 ndi 100 pa milliliter (pg/mL) . Picogram ndi gawo limodzi mwa magawo 1 trillion ya gramu—kuchuluka kwenikweni kwa mphindi imodzi!
Kumbukirani kuti mitundu iyi ya ma reference imatha kusiyana pang'ono pakati pa ma laboratories osiyanasiyana. Kuphatikiza apo, zotsatira zanu zitha kukhudzidwa ndi nthawi yomwe mwakhala mukusala kudya komanso kuchuluka kwa shuga m'magazi anu panthawi yoyezetsa. Chifukwa chake, nthawi zonse yerekezerani zotsatira zanu ndi mitundu ya ma reference yomwe yaperekedwa pa lipoti lanu la lab . Ngati muli ndi mafunso, kambiranani ndi dokotala wanu ku Nirogi Lanka.
Kodi muyenera kupita kwa dokotala liti kuti mudziwe kuchuluka kwa glucagon m'magazi anu?
Ngati muli ndi matenda a shuga ndipo nthawi zambiri mumakhala ndi shuga wochepa kapena wokwera m'magazi, ndikofunikira kufunsa dokotala wanu. Ngakhale kuti kuchuluka kwa glucagon sikumayesedwa nthawi zonse kwa aliyense amene ali ndi matenda a shuga, dongosolo lanu loyang'anira matenda a shuga lingafunike kusintha kuti muchepetse kusinthasintha kumeneku.
Ngakhale kuti mavuto ena okhudzana ndi glucagon ndi osowa, ngati mukukumana ndi zizindikiro, kupeza chomwe chikuyambitsa ndikofunikira. Nthawi zonse muziika patsogolo nthawi yokumana ndi dokotala wanu.
Kodi pali kusiyana kotani pakati pa Glucagon ndi Glycogen?
Izi ziwiri ndi zosiyana. Glycogen ndi mtundu wa shuga wosungidwa. Thupi lathu limasunga glycogen m'chiwindi ndi minofu.
Glucagon ndi homoni. Imagwira ntchito ngati chothandizira, kuwuza chiwindi kuti chisinthe glycogen yosungidwa kukhala shuga, yomwe imatulutsidwa m'magazi kuti ipereke mphamvu ku thupi lanu.
Kodi chimachitika ndi chiyani kwa Glucagon mukasala kudya?
Mukakhala mukusala kudya, glucagon ndi yofunika kwambiri kuti shuga m'magazi anu asatsike kwambiri, chifukwa thupi lanu sililandira shuga kuchokera ku chakudya.
Pa nthawi yosala kudya kwa nthawi yayitali, glucagon imalimbikitsa kupanga shuga kuchokera kuzinthu zopanda chakudya, monga mafuta, ma amino acid, ndi mapuloteni. Njira imeneyi imatchedwa gluconeogenesis .
Uthenga Womaliza Wopita Nawo Kunyumba
Monga mukuonera, glucagon ndi mahomoni ofunikira omwe amagwira ntchito mobisa kuti shuga m'magazi akhale wathanzi. Ngati mulibe matenda a shuga, mavuto a glucagon ndi osowa kwambiri.
Komabe, ngati nthawi zambiri mumakhala ndi zizindikiro za shuga wotsika kapena wokwera m'magazi, chonde funsani dokotala wanu. Angathe kuzindikira chomwe chimayambitsa vutoli ndikukupatsani chithandizo chofunikira. Kuika patsogolo thanzi lanu ndiye chinthu chofunikira kwambiri chomwe mungachite.
👩🏽⚕️ Mafunso Ofunsidwa Kawirikawiri (Mafunso Ofunsidwa Kawirikawiri)
💬 Kodi glucagon ndi mankhwala ofanana ndi insulin omwe amachepetsa shuga m'magazi?
Ayi, ndi zosiyana kwambiri! Glucagon ndi mahomoni omwe amapezeka m'thupi mwathu omwe amagwira ntchito ngati ofanana ndi insulin. Ngakhale kuti insulin idapangidwa kuti ichepetse shuga m'magazi mwathu, glucagon imagwira ntchito ngati njira yopulumutsira; shuga m'magazi mwathu ikatsika kwambiri (hypoglycemia), glucagon imauza chiwindi chanu kuti chitulutse shuga wosungidwa (glycogen) m'magazi mwathu, zomwe zimapangitsa kuti milingo yanu ikhale yotetezeka.
💬 N’chifukwa chiyani glucagon imasungidwa ngati chithandizo chadzidzidzi?
Ngati munthu wodwala matenda a shuga akumana ndi vuto lalikulu la hypoglycemia—zomwe zimapangitsa kuti asokonezeke kapena asamadziwe bwino—sangamwe shuga bwinobwino, chifukwa amatha kutsamwitsidwa. Munthawi zovuta izi, jakisoni wa glucagon (kapena cholembera) woperekedwa m'ntchafu kapena m'dzanja lakunja ukhoza kukweza shuga m'magazi mkati mwa mphindi zochepa, zomwe zimathandiza wodwalayo kuti abwererenso kuchira. Ngati izi zitachitika, nthawi zonse funsani ogwira ntchito zadzidzidzi (911) nthawi yomweyo mutatha kumwa mankhwalawa.
💬 Kodi n'kosavuta kupereka jakisoni wa glucagon kunyumba?
Inde. Mofanana ndi EpiPen yomwe imagwiritsidwa ntchito pa matenda oopsa, zida zadzidzidzi izi zimapangidwa kuti achibale kapena osamalira azizigwiritsa ntchito mosavuta kunyumba. Madera ena amaperekanso mankhwala opopera m'mphuno (monga Baqsimi). Ngati wina m'banja mwanu akugwiritsa ntchito insulin, kusunga zida zadzidzidzi za glucagon ndi njira yofunika kwambiri yotetezera yomwe ingapulumutse moyo. Nthawi zonse funsani dokotala wanu wa ku Nirogi Lanka kuti akuthandizeni kugwiritsa ntchito bwino.
Mawu Ofunika: glucagon, shuga m'magazi, hypoglycemia, hyperglycemia, matenda a shuga, kapamba, mahomoni
