Tiyeni tiphunzire zambiri zokhudza glucagon, yomwe imathandiza kulamulira kuchuluka kwa shuga m'thupi lanu.

Kodi munayamba mwadzifunsapo momwe kuchuluka kwa shuga m'magazi mwathu kumayendetsedwera? Pali chinthu chapadera chomwe chimathandiza ndi izi chotchedwa Glucagon. Monga ngwazi yaying'ono m'thupi lathu, Glucagon imateteza kuchuluka kwa shuga m'magazi mwathu kuti kusachepe kwambiri. Lero, tikambirana za Glucagon iyi mwatsatanetsatane komanso mosavuta.

Kodi Glucagon ndi chiyani?

Mwachidule, glucagon ndi mahomoni achilengedwe omwe matupi athu amapanga . Mukudziwa, amapangidwa ndi maselo a alpha mu kapamba wathu. Pamene kuchuluka kwa shuga m'magazi mwathu kumatsika, pamene sitidya kwa nthawi yayitali (kusala kudya nthawi yayitali), pamene tikuchita masewera olimbitsa thupi kwambiri, kapena tikamadya chakudya chokhala ndi mapuloteni ambiri, glucagon iyi imatulutsidwa.

Taganizirani izi, shuga ndiye mtundu waukulu wa shuga m'magazi mwathu. Timapeza shuga uyu kuchokera ku chakudya chomwe timadya ndi kumwa. Shuga uyu ndiye amene amapereka mphamvu ku ziwalo za thupi lathu, minofu, ndi mitsempha. Uli ngati mafuta a galimoto. Chifukwa chake, thupi lathu nthawi zambiri limasunga shuga m'magazi mwa njira yoyenera m'njira yovuta kwambiri. Kaya izi ndi zapamwamba kwambiri kapena zochepa kwambiri, matenda osiyanasiyana ndi kusasangalala zimatha kuchitika.

Jakisoni wa glucagon ndi ma spray a m'mphuno

Kuwonjezera pa glucagon yomwe imapezeka mwachilengedwe, palinso ma glucagon opangidwa. Izi zitha kuperekedwa ngati jakisoni kapena ngati spray youma m'mphuno. Mwina mwawonapo izi zikugwiritsidwa ntchito pazidzidzidzi, makamaka kwa anthu omwe ali ndi matenda a shuga a Mtundu 1 , pamene shuga m'magazi mwawo imatsika mwadzidzidzi (hypoglycemia). Glucagon yomwe imaperekedwa panthawiyi imatulutsa shuga wosungidwa m'chiwindi chathu ndikukweza shuga m'magazi mwathu mwachangu. Zili ngati kutipatsa 'mphamvu' pang'ono.

Kodi glucagon imagwira ntchito bwanji m'thupi lathu?

Ngati kapamba wanu akugwira ntchito bwino, thupi lanu lidzayang'anira mosamala kuchuluka kwa shuga m'magazi mwanu. Izi zimachitika makamaka ndi mahomoni awiri otchedwa glucagon ndi insulin . Mwachitsanzo, shuga m'magazi mwanu akatsika kwambiri (hypoglycemia), kapamba wanu amatulutsa glucagon yambiri. Glucagon iyi imathandiza kukweza kuchuluka kwa shuga m'magazi mwanu m'njira zingapo:

• Choyamba, glucagon imapita ku chiwindi chathu ndikusintha shuga wosungidwa mmenemo - womwe timautcha glycogen - kukhala chinthu chomwe tingagwiritse ntchito. Kenako chiwindi chimautulutsa m'magazi.
• Chachiwiri, glucagon imatha kuletsa chiwindi kutenga ndi kusunga shuga, zomwe zimapangitsa kuti shuga wambiri m'magazi.
• Chachitatu, amino acidGlucagon imathandizanso thupi kupanga shuga kuchokera kuzinthu zina.

Kumbukirani, zili ngati seesaw. Pamene shuga m'magazi atsika, glucagon imagwira ntchito, ndipo pamene shuga m'magazi akwera, insulin imagwira ntchito!

Ndi matenda ati omwe angagwirizane ndi mavuto ndi ntchito ya glucagon?

Tsopano tiyeni tiwone mavuto omwe angabuke ngati glucagon sigwira ntchito bwino.

Ngati muli ndi matenda a shuga, thupi lanu silingathe kutulutsa glucagon wokwanira pamene shuga m'magazi mwanu ndi wochepa. Izi zingakupangitseni kukhala ndi shuga wochepa m'magazi pafupipafupi, kapena ngakhale shuga wochepa kwambiri m'magazi . Chiwopsezochi chimakhala chachikulu makamaka ngati mumwa mankhwala ochepetsa shuga m'magazi monga insulin kapena sulfonylureas.

Kwa anthu ena omwe ali ndi matenda a shuga amtundu wachiwiri, kuchuluka kwa glucagon kumatha kukhala kokwera kuposa kwachizolowezi, poyerekeza ndi kuchuluka kwa shuga m'magazi. Ichi ndi chimodzi mwa zifukwa zomwe shuga m'magazi amakwera.

Ndikosowa kwambiri kuti mavuto okhudzana ndi kupanga glucagon achitike popanda matenda a shuga, koma pali zinthu zingapo zomwe zingachitike:

• Pancreatitis: Ngati mudwala matenda a shuga chifukwa cha kapamba ndipo mukumwa insulin, muthanso kudwala kusowa kwa glucagon. Izi zimawonjezera chiopsezo cha shuga wotsika m'magazi.
• Glucagonoma: Ichi ndi chotupa chosowa kwambiri cha kapamba. Chimatulutsa glucagon wochuluka. Izi zimayambitsa zizindikiro monga shuga wambiri m'magazi, ziphuphu pakhungu, komanso kuchepa thupi.
• Multiple Endocrine Neoplasia (MEN): Ichi ndi matenda osowa kwambiri a majini. Pachifukwa ichi, zotupa zimakula m'matenda angapo m'thupi lanu. Izi zikuphatikizapo kapamba.
• Zotsatira zoyipa za Pancreatectomy: Ngati pazifukwa zina gawo kapena lonse la kapamba wanu lachotsedwa, maselo omwe amapanga glucagon ndi insulin amatayika.

Kodi zizindikiro za mavuto okhudzana ndi glucagon ndi ziti?

Monga tafotokozera kale, kusakhazikika kwa kuchuluka kwa glucagon kungayambitse shuga wotsika m'magazi (hypoglycemia) kapena shuga wambiri m'magazi (hyperglycemia). Tiyeni tiwone zizindikiro zimenezo.

Zizindikiro za shuga wotsika m'magazi (hypoglycemia)

Tangoganizirani kuti mnzanu, Nilanthi, akumwa mankhwala a matenda ashuga. Tsiku lina, mwadzidzidzi amayamba kunjenjemera, kutuluka thukuta, komanso kumva chizungulire. Amawonekanso kuti sakulankhula bwino akamalankhula. Ngati zizindikirozi zichitika, zingatanthauze kuti shuga m'magazi mwake ndi wotsika kwambiri.

Zizindikiro zodziwika bwino ndi izi:

• Kugwedezeka, kunjenjemera
• Kutuluka thukuta ndi kumva kuzizira
• Chizungulire, kumva mutu wopepuka
• Kugunda kwa mtima
• Njala
• Kuvuta kukhazikika maganizo, chisokonezo

Chofunika: Ngati mukukumana ndi zizindikiro izi, ndikofunikira kwambiri kudya chakudya chopatsa shuga, chakudya chochuluka cha carbohydrate kapena chakumwa mwachangu . Izi zithandiza kuti shuga m'magazi mwanu abwerere mwakale. Ngati mukukumana ndi zizindikirozi pafupipafupi, muyenera kuonana ndi dokotala wanu.

Zizindikiro za shuga wambiri m'magazi (hyperglycemia)

Kuchuluka kwa shuga m'magazi (hyperglycemia) nthawi zambiri kumachitika chifukwa cha kusowa kwa insulin, osati vuto la glucagon yokha. Komabe, mavuto osowa a glucagon angayambitsenso kuchuluka kwa shuga m'magazi. Zizindikiro zoyamba ndi izi:

• Ludzu lobwerezabwereza ndi/kapena njala
• Maso osawoneka bwino
• Kukodza pafupipafupi ( kukodza pafupipafupi)
• Mutu

Ngati muli ndi zizindikiro izi, ndikofunikira kwambiri kukaonana ndi dokotala.

Ndi mayeso ati omwe amachitidwa kuti awone kuchuluka kwa glucagon?

Ngati muli ndi zizindikiro zina, dokotala wanu angakupatseni mayeso a magazi kuti muyeze kuchuluka kwa glucagon m'magazi anu. Pa mayesowa, dokotala kapena namwino amagwiritsa ntchito singano kuti atenge magazi kuchokera m'mitsempha yanu. Kenako amatumizidwa ku labu kuti akayesedwe.

Kodi kuchuluka kwa glucagon m'magazi ndi kotani?

Kawirikawiri, kuchuluka kwa glucagon komwe tiyenera kukhala nako m'magazi athu kumakhala pakati pa ma picogram 50 ndi 100 pa milliliter (pg/mL) . Picogram ndi gawo limodzi mwa magawo 1 trillion ya gramu! Ndikochepa kwambiri, eti?

Koma kumbukirani, miyezo yabwinobwino iyi imatha kusiyana pang'ono kuchokera ku labu kupita ku labu. Imathanso kusiyana kutengera nthawi yomwe mwakhala mukusala kudya komanso kuchuluka kwa shuga m'magazi mwanu panthawi yoyesedwa. Chifukwa chake, nthawi zonse yerekezerani zotsatira zanu ndi miyezo yomwe ili pa lipoti lanu la mayeso a magazi . Ngati muli ndi mafunso, lankhulani ndi dokotala wanu.

Kodi ndiyenera kupita liti kwa dokotala za kuchuluka kwa glucagon m'magazi anga?

Ngati muli ndi matenda a shuga ndipo nthawi zambiri mumakhala ndi shuga wochepa kapena wokwera m'magazi, ndikofunikira kukaonana ndi dokotala. Nthawi zambiri kuchuluka kwa glucagon sikumayesedwa mwa anthu omwe ali ndi matenda a shuga. Komabe, mungafunike kusintha kasamalidwe ka matenda a shuga kuti muchepetse matendawa.

Ngakhale mavuto ena okhudzana ndi glucagon ndi osowa, ngati muli ndi zizindikiro, ndikofunikira kupeza chomwe chikuyambitsa. Chifukwa chake, onetsetsani kuti mwawonana ndi dokotala wanu.

Kodi pali kusiyana kotani pakati pa Glucagon ndi Glycogen?

Kodi izi si zofanana? Glycogen ndi mtundu wa shuga womwe umasungidwa m'chiwindi.Matupi athu amasunga glycogen makamaka m'chiwindi ndi minofu.

Glucagon ndi mahomoni omwe amauza chiwindi kuti chisinthe glycogen kukhala shuga. Shuga ameneyo amalowa m'magazi ndipo angagwiritsidwe ntchito ngati mphamvu ndi matupi athu.

Kodi chimachitika ndi chiyani ndi glucagon panthawi yosala kudya?

Tikamasala kudya, glucagon ndi yofunika kwambiri kuti shuga m'magazi mwathu isachepe kwambiri. Izi zili choncho chifukwa matupi athu salandira shuga kuchokera ku chakudya panthawiyo.

Tikamasala kudya kwa nthawi yayitali, glucagon imapangitsa thupi kupanga shuga kuchokera ku zinthu zopanda chakudya - monga mafuta, ma amino acid, ndi mapuloteni. Njira imeneyi imatchedwa gluconeogenesis .

Pomaliza, ndiyenera kunena... (Uthenga Wopita Nawo Kunyumba)

Kotero, mwina mukumvetsa kuti glucagon ndi mahomoni ofunikira kwambiri omwe amathandiza kuti shuga m'magazi mwathu azikhala wathanzi 'mosadziwika bwino'. Sizokayikitsa kuti muli ndi matenda a shuga kapena mavuto okhudzana ndi glucagon.

Komabe, ngati mukukumana ndi zizindikiro za shuga wotsika m'magazi kapena shuga wambiri m'magazi, chonde onani dokotala wanu. Kenako angapeze chomwe chikuyambitsa ndikukupatsani chithandizo chomwe mukufuna. Kusamalira thanzi lanu ndiye chinthu chofunikira kwambiri.

` glucagon, shuga m'magazi, hypoglycemia, hyperglycemia, matenda a shuga, kapamba, mahomoni