Wopɛ sɛ wuhu ade kɔkɔɔ bi a ɛwɔ wo mogya mu ho asɛm? Momma yɛnka bilirubin sɔhwɛ no ho asɛm!

Oh, so woahyɛ no nsow pɛn sɛ ɛtɔ mmere bi a, titiriw wɔ nkokoaa a wɔawo wɔn foforo mu no, nipadua no dan kɔkɔɔ? Anaasɛ oduruyɛfo bi aka akyerɛ wo anaa obi a wunim no pɛn sɛ ɔnyɛ `(Bilirubin)` nhwehwɛmu? Ɛyɛ ade a ɛfata sɛ wobɛte ehu nka kakra bere a wote asɛmfua bilirubin no. Nanso mma ɛnhaw wo! Ɛnnɛ, yɛbɛka eyi ho asɛm tiawa, wɔ ɔkwan a wubetumi ate ase so.

Dɛn ne bilirubin? Momma yɛnte ase kɛkɛ!

Susuw ho hwɛ, mogya mu nkwammoaa kɔkɔɔ (a wɔsan frɛ no mogya mu nkwammoaa) a ɛwɔ yɛn nipadua mu no resesa bere nyinaa. Sɛ mogya mu nkwammoaa kɔkɔɔ dedaw no sɛe a, ɛma ade kɔkɔɔ bi a wɔfrɛ no bilirubin . Ɛte sɛ nea aka bere a woayi nneɛma dedaw afi hɔ no.

Afei saa bilirubin yi fa yɛn mogya mu kɔ mmerɛbo no mu. Mmɛn te sɛ adwumayɛbea bi a ɛwɔ yɛn nipadua mu, na ɛhohoro nneɛma a yɛmpɛ. Mmɛn no boaboa bilirubin yi ano, de ka nneɛma afoforo a wɔsɛe no ho, na ɛyɛ nsu bi a wɔfrɛ no "bile." Wunim, saa bilirubin yi ne nea ɛma bile nya kɔla kɔkɔɔ. Afei saa bile yi fa yɛn dwensɔtwaa mu na efi nipadua no mu. Yiw, saa bilirubin yi yɛ nea ɛma wo nsu a ɛwɔ wo nsu mu kɔla no fã kɛse.

Enti, dɛn ne bilirubin mogya mu nhwehwɛmu?

Ɛyɛ mmerɛw yiye. Oduruyɛfo bi fa mogya ketewaa bi fi ntini bi a ɛwɔ wo nsa mu mu na ɔde kɔ aduruyɛdan bi mu kɔhwɛ. Lab no susuw bilirubin dodow a ɛwɔ wo mogya mu. Wɔhwɛ sɛ ebia level no wɔ normal range mu, anaasɛ ɛkorɔn dodo anaasɛ ɛba fam dodo. Sɛ bilirubin dodow no nyɛ nea ɛfata a, ɛkyerɛ sɛ ebia ɔhaw bi bɛba baabi wɔ adeyɛ no mu a efi ase bere a saa mogya mu nkwammoaa kɔkɔɔ dedaw no mu paapae na ɛba awiei bere a woyi bilirubin no fi nipadua no mu no.

Dɛn na bilirubin dodow a ɛwɔ mogya mu no ka kyerɛ yɛn?

Nnuruyɛfo taa yɛ bilirubin nhwehwɛmu yi de hwɛ sɛnea wo mmerɛbo no te . Eyi yɛ mmerɛbo dwumadi ho nhwehwɛmu pii no mu biako pɛ. Sɛ saa gyinapɛn ahorow yi kɔ soro anaasɛ ɛba fam a, ebetumi akyerɛ sɛ mmerɛbo no wɔ adwennwen bi mu. Nanso, ɛnyɛ bere nyinaa na bilirubin dodow a ɛnteɛ no nkyerɛ sɛ ɔhaw bi wɔ mmerɛbo no mu. Ɛtɔ mmere bi a, ebia ɔhaw no da baabi foforo.

Dɛn nti na bilirubin dodow yi kɔ soro? (Hyperbilirubinemia) .

Nneɛma pii betumi ama bilirubin ayɛ kɛse wɔ wo mogya mu. Momma yɛnhwɛ nea wɔyɛ:

• Wo mogya mu nkwammoaa kɔkɔɔ no resɛe ntɛmntɛm dodo: Mogya mu nyarewa bi te sɛ mogya a ɛtɔ kɔ mogya mu no ma mogya mu nkwammoaa kɔkɔɔ no sɛe ntɛmntɛm dodo, na ɛma bilirubin dɔɔso dodo. Fa no sɛ adwumayɛbea bi a wogye nneɛma pii dodo.
• Ebia ɛbɛyɛ den ama wo mmerɛbo sɛ ebeyi bilirubin dodow a ɛfata mpo afi hɔ: Ɛtɔ mmere bi a eyi betumi aba sɛ mmerɛbo no nya biribi a awuduru wom mpofirim a. Anaasɛ, ebia mmerɛbo no ntumi nyɛ adwuma yiye esiane mmerɛbo mu yare a ɛtra hɔ kyɛ (`(Chronic liver disease)`).
• Wo biliary system no ntumi nnyae bile yiye:Ebia bile ntini anaa akisikuru no asiw, na ama bile no asan akɔ mogya no mu. Eyi nso betumi asi bere a akisikuru wɔ hɔ no.

Fa no sɛ, sɛ paipu a ɛde nsu ba nsukorabea mu no trɛw na paipu a ɛde nsu fi nsukorabea no mu no siw a, nsukorabea no bɛbow.

So bilirubin dodow betumi akɔ fam? (Hypobilirubinemia) .

Yiw, ɛtɔ mmere bi a bilirubin dodow betumi akɔ fam. Nnuru bi betumi de aba. Sɛ nhwɛso no, nnuru bi a ekum ɔyare mmoawa, nnuru a wɔde siw awo ano, nnuru a wɔde da, ne nnuru a wɔde sa akisikuru betumi ama bilirubin dodow so atew. Nanso, mpɛn pii no, bilirubin dodow a ɛba fam no nyɛ biribi a ɛhaw adwene wɔ ho.

Dɛn na ɛto bilirubin a ɛwɔ yɛn nipadua mu no ankasa?

Bilirubin yɛ ade a wɔsɛe no a woyi fi mogya mu nkwammoaa kɔkɔɔ dedaw mu. Mpɛn pii no, yɛn nipadua no fa dwensɔtwaa mu yi fi mu. Nanso, seesei wɔahu sɛ ɛwɔ mfaso nketenkete bi bere a wɔayi afi mu no. Nhwehwɛmu foforo kyerɛ sɛ bilirubin yɛ adwuma sɛ ade a ɛko tia ɔyare mmoawa na ebetumi aboa ma yɛabɔ yɛn ho ban afi koma ne ntini mu nyarewa ho.

Nanso, te sɛ biribiara no, sɛ ɛkɔ soro dodo a, ebetumi ayɛ awuduru . Sɛ bilirubin pii boaboa ano wɔ wo mogya mu a, ebia wo ho nyɛ wo dɛ. Ebetumi nso akanyan ntini a ɛwɔ wo honam ani no na ama wo ho ayɛ wo yaw.

Dɛn ne bilirubin a ɛdɔɔso ho sɛnkyerɛnne?

Bilirubin a ɛdɔɔso ho sɛnkyerɛnne titiriw ne jaundice . Eyi yɛ wo honam ani yɛ kɔkɔɔ ne w’ani fitaa. Mpɛn pii no, eyi ne sɛnkyerɛnne a edi kan a oduruyɛfo bɛhwehwɛ bere a ɔrehwɛ wo bilirubin dodow no.

Afei nso, sɛ bilirubin a ɛwɔ mogya no mu kɔ soro a, ɛbɔ mmɔden sɛ ɛbɛtotɔ piti wɔ nsu mu. Eyi betumi ama nsu no kɔla ayɛ tuntum (te sɛ tii kɔla).

Afei nso, sɛ wɔannyi bilirubin ankɔ nsu mu yiye a, nsu no betumi ayɛ kɔla a ɛyɛ hare (te sɛ dɔte) .

Nnipa binom mpo tumi twitwiw wɔn nipadua pii .

Ɔkwan bɛn so na wɔyɛ bilirubin mogya mu nhwehwɛmu?

Eyi yɛ mmerɛw yiye.

• Mpɛn pii no, wɔ ɔpanyin fam no, oduruyɛfo anaa ɔyarehwɛfo begye mogya ketewaa bi afi ntini bi a ɛwɔ wo nsa mu mu . Ebia wɔbɛka akyerɛ wo sɛ nnidi anaa nnom biribiara nnɔnhwerew kakraa bi ansa na wɔayɛ sɔhwɛ no. Ebia wobɛte ɛyaw kakra bere a wɔde ade no hyɛ mu na wɔayi afi mu no, nanso ebefi hɔ wɔ simma kakraa bi mu. Afei wɔde mogya no kɔ baabi a wɔyɛ nhwehwɛmu. Egye bere kakra ansa na amanneɛbɔ no asan aba.
• Sɛ akokoaa a wɔawo no foforo wɔ jaundice , oduruyɛfo no bɛhwɛ bilirubin dodow a ɛwɔ mu no mu ahwɛ sɛ ɛnkɔ soro dodo. Jaundice yɛ ade a ɛfata ma mmofra a wɔawo wɔn foforo na mpɛn pii no ɛnyɛ biribi a ɛsɛ sɛ ɛhaw wɔn ho. Nanso, sɛ bilirubin dodow kɔ soro dodo a, ebetumi apira akokoaa no.Wɔtaa gye mogya fi nkokoaa mu denam ade ketewaa bi (asen mu dua) a wɔde twitwiw wɔn nan ase so . Eyi yɛ sɔhwɛ a wɔtaa yɛ wɔ nkokoaa a wɔawo wɔn foforo so.

Dɛn na ɛwɔ amanneɛbɔ a menya no mu? Ɛkyerɛ dɛn?

Nhwehwɛmu amanneɛbɔ a wo nsa bɛka no bɛkyerɛ bilirubin dodow a ɛwɔ wo mogya mu wɔ dodow mu. Nokwarem no, bilirubin ahorow abien na ɛwɔ wo mogya mu: bilirubin a ɛkɔ mmerɛbo no mu ma wɔhohoro ho, ne bilirubin a efi mmerɛbo no mu ba bere a wɔahohoro ho awie no. W’amanneɛbɔ no bɛkyerɛ saa ahorow abien yi wɔ ɔkwan soronko so, ne bilirubin nyinaa nso. Wɔtaa kyerɛ no wɔ unit ahorow a wɔfrɛ no milligrams per deciliter (mg/dL) mu.

Dɛn ne Bilirubin a Ɛkɔ Tẽẽ ne Nea Ɛnkɔ Tẽẽ? (Conjugated vs. Nea Ɛnyɛ Nkyekyɛm) .

Sɛ yɛbɛka no tiawa a:

• Bilirubin ko a ɛkɔ mmerɛbo a wɔbɛhohoro no mu ne "Unconjugated" bilirubin . Ɛnpete nsu mu. Ɛkɔ mmerɛbo a ɛkyekyere protein bi a wɔfrɛ no albumin wɔ mogya no mu no mu. Eyi nti na ɛtɔ mmere bi a wɔfrɛ no "Indirect" bilirubin wɔ amanneɛbɔ no mu no. Efisɛ wontumi nsusuw no tẽẽ. Wohu denam bilirubin a wɔde afrafra a woyi fi bilirubin nyinaa mu no so.
• Sɛ mmerɛbo no tew bilirubin yi ho wie a, ɛkyekyere asikre molecule bi na ɛma ɛyɛ den wɔ nsu mu. Ɛno ansa na ebetumi afa dwensɔtwaa a wɔde bile afra mu no mu. Wɔfrɛ saa bilirubin a mmerɛbo no tew ho yi "conjugated" bilirubin . Wɔ amanneɛbɔ no mu no, wɔsan frɛ no "direct" bilirubin , efisɛ wobetumi asusuw no tẽẽ.

So wote ase? Baako ansa na akɔ mmerɛbo mu, na biako nso bere a mmerɛbo no atew ho akyi.

Bilirubin dodow bɛn na ɛsɛ sɛ yɛhaw yɛn ho?

Nsonsonoe kakra betumi aba nea lab biara bu no sɛ bilirubin dodow a ɛfata no mu. Nanso mpɛn pii no, wobu bilirubin dodow a ne nyinaa yɛ 0.2 kosi 1.3 mg/dL sɛ ɛyɛ ade a ɛfata ma mpanyimfo ne mmofra . Sɛ wo dodow boro eyi so a, ebia wo duruyɛfo bɛyɛ nhwehwɛmu foforo de ahu nea ɛde ba. Ebetumi akyerɛ tebea bi a ɛsɛ sɛ wɔhwɛ so. Nanso, bilirubin a ɛkɔ soro ankasa nyɛ tebea a emu yɛ den na mpɛn pii no enhia sɛ wɔsa.

Nanso, wɔ mmofra a wɔawo wɔn foforo fam no, asɛm no yɛ soronko kakra. Bilirubin dodow a ɛfata wɔ nkokoaa mu no betumi afi 1.0 mg/dL kosi 12.0 mg/dL. Mpɛn pii no, wɔhwɛ kwan sɛ bilirubinemia a ɛboro so wɔ mmofra a wɔawo wɔn foforo mu na ɛno ankasa befi hɔ. Nanso, nnuruyɛfo bɛkɔ so ahwɛ tebea no so ahwɛ sɛ bilirubin dodow no rekɔ soro ntɛmntɛm dodo anaasɛ ɛba fam dodo. Sɛ wɔyɛ saa a, ebetumi ayɛ tebea a emu yɛ den na apira akokoaa no.

Bilirubin dodow bɛn na ɛyɛ hu ma akokoaa a wɔawo no foforo?

Nnuruyɛfo kamfo kyerɛ sɛ wobefi ase agyina bilirubin dodow so asa mmofra a wɔawo wɔn foforo yare.Sɛ ɛboro 15 mg/dL wɔ nnɔnhwerew 48 a edi kan no mu, anaasɛ ɛboro 20 mg/dL wɔ nnɔnhwerew 72 akyi a. Wɔ saa dodow yi mu no, bilirubin a wɔmfa nkabom no dodow boro albumin dodow a ɛwɔ hɔ a ɛbɛkyekyere no so. Afei bilirubin a wɔmfa nkabom yi betumi atwa mogya ne amemene akwanside no akɔ abofra a wɔawo no foforo no amemene mu na asɛe amemene a ɛrenyin no. Eyi betumi ama amemene no asɛe wɔ akwan horow so, tebea bi a wɔfrɛ no kernicterus .

Saa asiane yi nyɛ ade koro wɔ mpanyimfo ne mmofra a wɔanyinyin fam. Mpanyimfo amemene nyɛ nea ɛyɛ mmerɛw saa, na bilirubin a wɔmfa nka ho no ntaa nkɔ soro saa wɔ mpanyimfo mu. Mmofra a wɔawo wɔn foforo no yɛ bilirubin ntɛmntɛm sen mpanyimfo, na wɔde ka bom brɛoo kɛse.

Nneɛma pii nti na conjugated bilirubin ``(Conjugated hyperbilirubinemia)`` tumi kɔ soro wɔ mpanyimfo mu. Wɔ mpanyimfo mu no, bilirubin a ɛkɔ soro no betumi ayɛ tebea bi a asiane wom ho sɛnkyerɛnne, nanso bilirubin ankasa nyɛ asiane kɛse (a ɛnte sɛ nkokoaa mu).

Sɛ wo bilirubin dodow kɔ soro a, dɛn na ɛkyerɛ?

Sɛ wo nipadua no sɛe mogya mu nkwammoaa kɔkɔɔ ntɛmntɛm sen sɛnea wo mmerɛbo betumi atew a, bilirubin dodow a ɛnyɛ nea wɔaka abom (a ɛnteɛ) no betumi akɔ soro. Eyi betumi akyerɛ nneɛma te sɛ:

• Yare a ɛma mogya tu
• Sickle cell yare a ɛma obi nya yare
• Ade bɔne a ɛba bere a wɔde mogya ma obi

Nneɛma a ɛtaa ma bilirubin a wɔmfa nka ho no kɔ soro wɔ nkokoaa a wɔawo wɔn foforo mu:

• Awo a ɛba ntɛm
• Mogya dodow a ɛnhyia wɔ akokoaa no ne ɛna no ntam
• Nneɛma bi a wɔyɛ wɔ nufusu mu ho

Sɛ wo nipadua no wɔ ɔhaw wɔ bilirubin a ebeyi afi hɔ yiye no mu a, ebia wo bilirubin dodow a wɔde afrafra (tẽẽ) no bɛkɔ soro. Eyi betumi akyerɛ sɛ wowɔ biliary disease anaa gallstones. Nhwɛso ahorow:

• Abo a wɔde yɛ akisikuru
• Cholecystitis a ɛma obi ho kyere no
• Ntini a ɛma mogya tu no mu ɔfe (Cholangitis) .

Bilirubin ahorow abien no nyinaa betumi ayɛ kɛse wɔ mogya no mu esiane tebea horow a ɛka sɛnea wo mmerɛbo tumi yi bilirubin fi hɔ nti.

Ebia wo bilirubin dodow nyinaa bɛkɔ soro, bere a wufi ase nom aduru foforo, anaasɛ bere a wonom nsa pii, anaasɛ esiane bere tiaa bi a ɛyɛ mmerɛbo no nti. Anaasɛ, ebetumi aba sɛ efi mmerɛbo mu yare a emu yɛ den anaa enni sabea. Nneɛma bi a ɛde ba no bi ne:

• Nyarewa te sɛ ɔyare mmoawa a ɛma obi nya mmerɛbo mu yare ne mononucleosis.
• Awosu mu tebea horow a ɛka bilirubin a ɛma nipadua no yɛ adwuma, te sɛ Gilbert yare, Wilson yare, ne Crigler-Najjar yare.
• Hepatitis a awuduru wom (a nsa anaa nnubɔne na ɛde ba) .
• Cirrhosis ne mmerɛbo a entumi nyɛ adwuma yiye

Sɛ nneɛma bi a ɛnteɛ wɔ me sɔhwɛ amanneɛbɔ no mu a, dɛn na ɛba akyi?

Oduruyɛfo bɛhwɛ wo yare no ho sɛnkyerɛnne ne w’ayaresa ho abakɔsɛm de abɔ mmɔden sɛ obehu nea ebetumi de aba. Ɛsono sɛnea biribiara a ɛde ba no wɔ ayaresa a wobetumi apaw. Ebia wɔbɛhyɛ sɛ wɔnyɛ mogya mu nhwehwɛmu pii ne mfoniniyɛ mu nhwehwɛmu na ama wɔahu wo tebea no yiye. Ebia wɔbɛsan asɔ wo bilirubin dodow nso ahwɛ sɛ ɛrekɔ soro bio anaa. Sɛ wo ba a wɔawo no foforo no bilirubin dodow dɔɔso dodo a, ebia wɔbɛkamfo ayaresa a ɛbɛma wɔatew so akyerɛ.

Dɛn ne ayaresa ahorow a wɔde sa bilirubin a ɛkɔ soro wɔ nkokoaa a wɔawo wɔn foforo mu?

Ayaresa a wɔtaa de ma bilirubin dodow a wɔtew so wɔ mmofra a wɔawo wɔn foforo mu ne phototherapy . Eyi kyerɛ sɛ oduruyɛfo de wo ba no to kanea soronko bi ase. Saa hann yi ma hann bi a ɛyɛ bruu ba. Saa hann yi bubu bilirubin no ma ɛyɛ nea nsu ntumi nwura mu. Eyi ma wotumi yi fi nipadua no mu a ɛnyɛ nea ɛka bom wɔ mmerɛbo no mu. Eyi ma bilirubin a wɔmfa nkabom no ntumi nkɔ akokoaa no amemene mu ntini mu.

Wobɛyɛ dɛn atew wo bilirubin dodow so?

Sɛ wɔsa tebea a ɛma wo bilirubin dodow kɔ soro no yiye na wodi so a, wo bilirubin dodow so bɛtew. Eyi gyina nea ɛde ba no so. Wo duruyɛfo no ne wo bɛkasa afa akwan horow a wobɛfa so asa yare no anaasɛ ɛbɛtew ne nkɛntɛnso so ho.

Mpɛn pii no, wubetumi atew nhyɛso a ɛwɔ wo mmerɛbo so no so denam nsa ne nnuru a ɛho nhia (nnuru a wɔtɔn (OTC) mpo a wubetwa sɛnea wubetumi biara), ne aduan pa a wubedi so.

Dɛn ne bilirubin nsu mu nhwehwɛmu?

Ebia wɔbɛyɛ wo nsu mu bilirubin nhwehwɛmu sɛ nsu mu nhwehwɛmu fã. Ebia eyi yɛ akwahosan ho nhwehwɛmu a wɔyɛ no daa no fã. Anaasɛ, ebia wo duruyɛfo bɛhyɛ nhwehwɛmu yi pɔtee sɛ wowɔ jaundice anaasɛ wo nsu a ɛyɛ tumm a . Bilirubin a ɛwɔ wo nsu mu (bilirubinuria) nyɛ ade a ɛfata. Nanso, sɛ wo conjugated bilirubin dodow dɔɔso yiye a, eyi betumi asi.

Wɔ sɔhwɛ yi mu no, oduruyɛfo bɛma wo toa ketewaa bi a wode bɛfa nsu a wode bɛkɔ. Wɔbɛsan nso ama wo ``sanitary wipe`` a wode bɛhohoro wo honam ani ansa na woatoto wo ho. Toa no benya agyiraehyɛde bi wɔ so a ɛkyerɛ nsu dodow a ɛsɛ sɛ wɔboaboa ano. Sɛ woanka toa no mu a, wobɛboaboa nhwɛsode no ano na wode ama oduruyɛfo no. Wɔde bɛkɔ lab bi akɔsɔ ahwɛ.

Adeɛ a Ɛho Hia Sen Biara - Nneɛma a Ɛsɛ sɛ Wokae (Take-Home Message) .

Okay, enti yɛaka bilirubin ho asɛm pii seesei, ɛnte saa?

Sɛ wuhu sɛ kɔla kɔkɔɔ bi wɔ wo nipadua anaa w’ani so (jaundice) a, ɛyɛ sɛnkyerɛnne a ɛkyerɛ sɛ akyinnye biara nni ho sɛ ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn na woyɛ bilirubin nhwehwɛmu.Jaundice fi ase ba bere a bilirubin dodow du dodow a ɛfata mmɔho abien kosi abiɛsa no. Ebia wubehu nso sɛ wo nsu no yɛ tuntum (ɛyɛ tii kɔla) wɔ saa dodow yi mu.

Nanso, ɛtɔ mmere bi a bilirubin dodow betumi ayɛ kɛse a enni sɛnkyerɛnne biara. Bilirubin nhwehwɛmu betumi aboa wo duruyɛfo ma asi tebea horow bi a wosusuw sɛ ɛwɔ hɔ no so dua na wahu nea ɛde ba.

Enti, nsuro bere a wote asɛmfua bilirubin no. Ɛyɛ adeyɛ a ɛfata wɔ yɛn nipadua mu no fã. Nanso, sɛ ne dodow sesa a, ɛho hia sɛ wuhu nea ɛde ba na sɛ ɛho hia a, wonya ayaresa. Sɛ wowɔ nsɛmmisa bi a, ntwentwɛn wo nan ase da sɛ wo ne wo duruyɛfo bɛkasa. Wɔwɔ hɔ sɛ wɔbɛboa wo.

` Bilirubin, bilirubin nhwehwɛmu, jaundice, atiridii kɔkɔɔ, mmerɛbo, mogya mu nkwammoaa kɔkɔɔ, nkokoaa a wɔawo wɔn foforo