Ɛtɔ mmere bi a, obi a ɔwɔ Parkinson yare no hwere ne nipadua no kankyee so tumi mpofirim, ne nipadua yɛ den , na wofi ase wosow. Yɛfrɛ eyi sɛ ‘off’ episode. Ɛte sɛ nea ‘wɔdum’ switch bi. Enti ɛnnɛ yɛrebɛka aduru soronko bi a wɔde ma ahotɔ ntɛm wɔ mmere te sɛ eyinom mu ho asɛm. Ɛno yɛ aduru a wɔde hyɛ kasa ase a wɔfrɛ no apomorphine.
Dɛn ne Apomorphine yi?
Sɛ yɛbɛka no tiawa a, eyi yɛ aduru a wɔde ma de siw Parkinson yare no ho sɛnkyerɛnne ano. Nnuru bi a wɔfrɛ no dopamine boa ma yɛhwɛ yɛn amemene no kankyee ne nneɛma a ɛyɛ biako so. Fa no sɛ dopamine yi yɛ ɔbɔfo a ɔhwɛ yɛn nipadua no kankyee so. Wɔ Parkinson yare mu no, ɔbɔfo yi dodow so tew wɔ amemene no mu. Ɛno ne bere a sɛnkyerɛnne te sɛ wosow ne ne ho a ɛyɛ den no da adi.
Enti nea saa aduru yi, Apomorphine, yɛ ne sɛ ɛyɛ adwuma te sɛ saa dopamine somafo a ayɛ mmerɛw no na ɛboa amemene no ma ɛsan de nkrasɛm mena yiye. Ne saa nti, Parkinson yare no ho sɛnkyerɛnne so tew ntɛmntɛm na nipadua no te nka sɛ ne ho ye kakra.
Saa aduru yi nso wɔ brand din KYNMOBI ase. Nanso, esiane sɛ wobetumi de ayɛ nneɛma afoforo nso nti, ɛbɛyɛ papa sɛ wo ne wo duruyɛfo bɛkasa afa nneɛma biara a ɛhaw wo ho.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woanom saa aduru yi
Ɛho hia yiye sɛ wo duruyɛfo hu w’aduruyɛ ho abakɔsɛm nyinaa ansa na wakyerɛw saa aduru yi ama wo. Hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo sɛ wowɔ tebea horow a wɔabobɔ din wɔ ase ha no bi a.
- Sɛ wotaa nya adwenemhaw anaa wotɔ piti a: Ɛtɔ mmere bi a, saa aduru yi tumi ma wo mogya so tew. Enti sɛ wowɔ saa ɔhaw yi dedaw a, ɛho hia sɛ woka ho asɛm.
- Koma mu yare: Sɛ wowɔ komayare, titiriw koma a ɛbɔ a ɛnteɛ.
- Mogya mmoroso a ɛba fam: Sɛ wo mogya so tew a.
- Sɛ woanya akisikuru a.
- Asaabo anaa mmerɛbo mu yare: Sɛ w’asaabo anaa wo mmerɛbo ntumi nyɛ adwuma yiye a.
- Ahurututu mu nyarewa: Ɔhome a ɛyɛ den te sɛ ayamtu.
- Adwene mu akwahosan ho haw ahorow: Tebea horow te sɛ adwenemhaw.
- Sɛ wunya nna a wuntumi nni so awiabere a.
- Sɛ woyɛ obi a ɔtaa nom nsa a.
- Sɛ woanyinsɛn anaasɛ worebɔ mmɔden sɛ wubenyinsɛn a.
- Sɛ woyɛ ɛna a worema nufu a.
- Sɛ wowɔ akisikuru afoforo a: Ka kyerɛ wo duruyɛfo sɛ wowɔ apomorphine, sulfites, nnuru afoforo, nnuan, nneɛma a wɔde siesie nneɛma, anaa nnuru a wɔde yɛ nneɛma bi a.
Ɛho hia paa ma w’ankasa ahobammɔ sɛ wobɛka saa nsɛm yi akyerɛ oduruyɛfo no a womfa nsie.
Ɔkwan bɛn so ankasa na wode saa aduru yi di dwuma?
Ɔkwan a wɔfa so de eyi di dwuma no yɛ mmerɛw yiye, nanso ɛyɛ biribi a ɛsɛ sɛ wɔyɛ no fɛfɛɛfɛ yiye.
1. Fa no bere ano: Fa eyi di dwuma bere a woanya ‘off’ episode ara pɛ, sɛnea wo duruyɛfo aka akyerɛ wo no ara pɛ.
2. Yi fi packet no mu: Fa aduru no sie foil kotoku no mu kosi sɛ wubesiesie wo ho sɛ wobɛnom.
3. Ɛsɛ sɛ nsa yɛ nwunu: Hwɛ sɛ wo nsa ayow ansa na wode aduru no adi dwuma. Sɛ wode nsa a ɛyɛ nsu ka ho a, ebetumi ayow.
4. Fa sini no to wo tɛkrɛma ase: Fa sini no to wo tɛkrɛma ase na ma ɛntetew na wo nipadua no nnye.
5. Nwe, mmubu, anaa nsɛe: Nwe , mmubu, anaa nsɛe aduru yi wɔ w’anom. Ɛsɛ sɛ ɛpete wɔ wo tɛkrɛma ase.
Nnyae saa aduru yi nom mpofirim a wonkɔ wo duruyɛfo nkyɛn. Eyi betumi de ɔhaw ahorow a emu yɛ den aba na ebetumi ama wo tebea no asɛe kɛse.
Sɛ wonom boro so a, dɛn na wobɛyɛ?
Sɛ wususuw sɛ woanom aduru yi dodo a, mma wo ho nnyɛ wo hu. Kɔ ayaresabea Emergency Department (ETU) a ɛbɛn wo ntɛm ara. Anaasɛ, frɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea no .
Na sɛ mepa dose bi nso ɛ?
Eyi nyɛ aduru a ɛsɛ sɛ wɔnom bere koro mu da biara da. Wɔde di dwuma bere a ‘off’ bere nkutoo, bere a Parkinson ho sɛnkyerɛnne no kɔ soro mpofirim no. Enti ‘missed a dose’ mfa ha. Nanso, sɛ wonom nnuru a edi kan no bere a ‘off’ bere bi rekɔ so na wo sɛnkyerɛnne ahorow no ankɔ yiye a, nnom dodow a ɛto so abien saa bere no. Wo ne wo duruyɛfo nka eyi ho asɛm.
Nnuru afoforo a ebia ɛne aduru yi bedi nkitaho
Eyi yɛ ɔfã a ɛho hia paa. Nnuru bi betumi de asiane aba bere a wɔde Apomorphine ka ho no.
| Mfa aduru yi nka wo ho da! | |
|---|---|
| Cisapride na ɔkyerɛwee | Pimozide a wɔde yɛ nnuru |
| Dronedarone a wɔfrɛ no Dronedarone | Thioridazine a wɔde ma |
| Ketoconazole a wɔde ma | Levoketoconazole a wɔde ma |
| Nnuru bi a wɔde sa ɔfe ne akisikuru (sɛ nhwɛso no, dolasetron, granisetron, ondansetron, palonosetron) . | |
| Hwɛ yiye paa bere a wode eyinom redi dwuma ne | |
|---|---|
| Nsaden | Nnuru a wɔde da |
| Nnuru bi a wɔde sa adwenemhaw (e.g. amitriptyline) . | Ntini a ɛma ntini mu dwo |
| Opioid ahorow bi a wɔde sa ɛyaw anaa ɔfe | Nitroglycerin a wɔde yɛ aduru |
| Nnuru bi a wɔde sa akisikuru (Antihistamines) . | Nnuru te sɛ Haloperidol ne Metoclopramide |
Saa nsɛm a wɔahyehyɛ yi nwie pɛyɛ, enti ka nnuru a worenom nyinaa ho asɛm kyerɛ wo duruyɛfo (a vitamin, nnuru a wɔde di dwuma wɔ amanne kwan so, nhabannuru, ne nhabannuru mpo ka ho) .
Nneɛma a ɛsɛ sɛ wohwɛ yiye wɔ ho bere a worenom aduru yi
- Akisikuru ne akisikuru: Saa aduru yi betumi ama obi ho ayɛ no yaw na wafe. Ɛtɔ mmere bi a, ebetumi ayɛ nea emu yɛ den koraa. Wo duruyɛfo bɛkyerɛw aduru foforo ama eyi. Mfa nnuru a wɔtɔn a ɛko tia akisikuru. Ɛnyɛ nnuru a wɔde ko tia akisikuru nyinaa na ɛne aduru yi hyia.
- Dae a wobɛda mpofirim:Eyi ho hia paa. Sɛ wonom saa aduru yi a, ebia wobɛda mpofirim a wommɔ wo kɔkɔ biara. Fa no sɛ woreka kar, woredidi, anaa wo ne obi rekasa na woada a wunhu. Eyi yɛ asiane kɛse. Enti , nka kar anaa mfa mfiri nni dwuma kosi sɛ wubehu sɛnea aduru yi ka wo. Sɛ wuhyia eyi a, ka kyerɛ wo duruyɛfo ntɛm ara.
- Nsã: Sɛ obi ne nsa ka saa aduru yi ho a, ɛma asiane a ɛwɔ hɔ sɛ obi betu, ne ho atɔ piti, na wada mpofirim no yɛ kɛse.
- Nitroglycerin: Sɛ worenom nitroglycerin wɔ wo kasa ase ama komayare bi a, nnuru abien yi a wobɛka abom no betumi ama wo mogya so atew wɔ ɔkwan a ɛyɛ hu so. Enti, sɛ ɛho hia sɛ wonom nitroglycerin a, di kan da . Afei fa aduru no. Anyɛ yiye koraa no, da fam simma 45 bere a woanom aduru no awie no.
Nneɛma bɔne bɛn na wobetumi ahu?
Te sɛ aduru biara no, eyi betumi anya ɔhaw ahorow. Ebi yɛ aniberesɛm, ebi nso abu so.
| Nneɛma bɔne a anibere wom a ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo no ntɛm ara | |
|---|---|
| Nneɛma a ɛma obi ho yɛ no hyew | Wora mu akisikuru, ɛyaw, anim, anofafa, tɛkrɛma, aniwa a ɛho ahonhon, ɛyɛ den sɛ wobɛhome anaa wobɛmene. |
| Dae a wɔda mpofirim | Dae a wɔda awiabere a wɔmfa kɔkɔbɔ biara mma . |
| Mogya mmoroso a ɛba fam | Adwene a ɛyɛ basaa, adwenemhaw, aniwa a ɛyɛ kusuu. |
| Nsakrae a ɛba koma a ɛbɔ mu | Sɛ wote nka sɛ wo koma rebɔ ntɛmntɛm anaasɛ ɛnte saa, wo koko mu yaw, ɛyɛ den sɛ wobɛhome. |
| Adwene mu nsakrae | Nneɛma a enni hɔ a wohu anaa wote (hallucinations), nsakrae a ɛyɛ soronko wɔ suban mu. |
| Nkate a wontumi nni so | Nhyɛso a wontumi nni so sɛ wɔmfa wɔn ho nhyɛ dwumadi ahorow te sɛ kyakyatow, adidi mmoroso, nna mu dwumadi, ne sika a wɔsɛe no a ɛho nhia mu. |
| mogya a ɛtɔ kɔ mogya mu a ɛma mogya tu | Ɔbrɛ a ɛyɛ soronko, adwenemhaw, ahome a ɛyɛ den, nsu a ɛyɛ tumm, honam ani anaa aniwa a ɛyɛ kɔkɔɔ. |
| Nsunsuansoɔ bɔne a wɔtaa hu, nanso sɛ ɛkɔ so a, ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfoɔ | |
| Adwene a ɛyɛ basaa | Dae a ɛma obi da |
| Tipaeɛ | Akisikuru ne ɔfe |
| Baabi a na aduru no wɔ, kyerɛ sɛ, tɛkrɛma ase no, ɛyaw, ɔfe, anaa ɛyaw wɔ hɔ. | |
Ɔkwan bɛn so na wɔde aduru no sie?
- Twe wo ho fi mmofra ne afieboa ho. Eyi ho hia paa.
- Fa sie wɔ dan mu hyew (a ɛwɔ digrii Celsius 20-25 ntam).
- Fa aduru no sie foil packet no mu kosi sɛ ɛbɛyɛ krado sɛ wode bedi dwuma.
- Tow nnuru a ne bere atwam gu.
Bisa wo duruyɛfo sɛnea wobɛtow nnuru a wɔmfa nni dwuma anaasɛ ne bere atwam agu dwoodwoo.
Nkrasɛm a Wɔde Kɔ Fie
- Apomorphine yɛ aduru a wɔde di dwuma wɔ kasa ase a ɛma wotumi di sɛnkyerɛnne ahorow so ntɛmntɛm wɔ Parkinson yare no fã a ‘ɛyɛ adwuma’ no mu.
- Ansa na wode saa aduru yi bedi dwuma no, ka w’akwahosan tebea nyinaa ne nnuru afoforo a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo.
- Ebia wobɛda nso a wunnim bere a worenom aduru yi. Enti, kwati dwumadi ahorow a ehia sɛ woma w’ani da hɔ, te sɛ karka, kosi sɛ wubehu sɛnea aduru yi ka wo nipadua.
- Sɛnea ɛbɛyɛ a wobɛtew adwenemhaw ne ɔtopae so no, sɔre mpɛn pii bere a wote ase anaa woda fam no.
- Hu nneɛma bɔne a anibere wom (te sɛ akisikuru, nsakrae a ɛba koma a ɛbɔ mu, adwene mu nsakrae) a ɛhwehwɛ sɛ wokɔ ayaresabea ntɛm ara.
- Saa aduru yi yɛ wo nkutoo dea. Mfa nkyerɛ afoforo da.
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