So wo duruyɛfo akyerɛw wo anaa obi a ɔbɛn wo aduru a wɔfrɛ no Thioridazine? Sɛ saa a, momma yɛnka aduru yi, nea ɛyɛ, ne nea ɛsɛ sɛ wohwɛ yiye wɔ ho bere a wode redi dwuma no ho asɛm tiawa. Sɛ wokenkan eyi wie a, wubenya aduru yi ho ntease pa.
Sɛ yɛbɛka no tiawa a, Thioridazine yɛ aduru a wɔde sa adwenemyare te sɛ adwenemhaw . Nnuruyɛfo taa kyerɛw ma bere a nnuru afoforo adi nkogu anaasɛ ɛyɛ den dodo sɛ wobegyina ano no. Ɛka nnuru bi a wɔfrɛ no nnuru a ekum adwene mu yare ho. Ɛyɛ adwuma denam dopamine, nnuru bi a ɛwɔ yɛn amemene mu a ɛboa ma yɛdi yɛn adwene so no dodow a ɛkari pɛ so.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woanom saa aduru yi
Ansa na wubefi ase anom saa aduru yi no, sɛ wowɔ ayaresa tebea anaa ɔhaw ahorow a edidi so yi mu biara a, ɛsɛ sɛ wobɔ wo duruyɛfo amanneɛ ampa . Saa nsɛm yi ho hia yiye wɔ ayaresa a ɛfata a wobehu mu.
| Tebea/Ɔhaw a Ɛwɔ Hɔ | Nkyerɛmu |
|---|---|
| Amemene ne ntini ahorow | Amemene mu akisikuru, adwenemhaw, ti a opira, akisikuru, Parkinson yare, ntini a ɛhwɛ so ho haw ahorow. |
| Koma ne mogya | Koma mu yare, koma a ɛbɔ a ɛnbɔ daa, mogya mmoroso a ɛba fam, mogya mu nkwammoaa a ɛso tew (fitaa, kɔkɔɔ, mogya nkwammoaa). |
| Ayaresa mu tebea afoforo | Asikreyare, mmerɛbo mu yare, atiridiinini, prostate yare, ahurututu anaa ɔhome mu yare (e.g. ayamtu), dwensɔtwaa a ɛsiw, ɛyɛ den sɛ ɔbɛmene, ɛyɛ den sɛ ɔbɛtow. |
| Asetra kwan ne nneɛma a ɛma obi ho yɛ no yaw | Sɛ wotaa nom nsa, wunyinsɛn anaa worebɔ mmɔden sɛ wubenyinsɛn, woyɛ ɛna a ɔma nufu, anaasɛ wo ho yɛ wo hyew wɔ Thioridazine anaa nnuru, nnuan, anaa nnuru afoforo ho a. |
Ɔkwan bɛn so na ɛsɛ sɛ mede saa aduru yi di dwuma?
Ɛsɛ sɛ wɔde ano ka aduru yi a wɔde nsu kuruwa ka ho. Fa dodow a wɔakyerɛw ama wo no, wɔ bere a wɔahyɛ no mu, sɛnea wo duruyɛfo anaa ade a wɔde ahyɛ mu no kyerɛ no. Mfa nea ɛboro dodow a wɔahyɛ ato hɔ no esiane biribiara nti.
Nea ɛho hia sen biara ne sɛ worennyae saa aduru yi nom mpofirim a wo duruyɛfo nka ho afotu. Saa a wobɛyɛ no betumi ama obi ayɛ n’ade a anibere wom. Sɛ wugyae aduru no nom a, wo duruyɛfo bɛkyerɛkyerɛ sɛnea wobɛyɛ no mu.
Ahwɛyiye titiriw ho hia bere a wode aduru yi rema mmofra no, enti wo ne wo duruyɛfo nka ho asɛm.
Na sɛ menom nnuru pii nso ɛ? (Nnuru a wɔde ma boro so) .
Sɛ wususuw sɛ woanom nnuru pii sen sɛnea wususuw a, frɛ Ɔman Awuduru Ho Amanneɛbɔbea a ɛwɔ Colombo Ɔman Ayaresabea no ntɛm ara . Anaasɛ kɔ ayaresabea a ɛbɛn wo no Emergency Treatment Unit (ETU) .
Yɛsrɛ sɛ hyɛ no nsow: Wɔakyerɛw saa aduru yi ama wo nkutoo. Mfa nnkyerɛ afoforo.
Sɛ wopa nnuru dodow bi a, dɛn na ɛsɛ sɛ woyɛ?
Sɛ wo werɛ fi sɛ wobɛnom dose bi a, fa no bere a woakae ara pɛ. Nanso, sɛ ɛkame ayɛ sɛ bere aso sɛ wobɛma wo dodow a edi hɔ no a, twa dodow a woayera no so na fa wo dodow a edi hɔ no wɔ bere a woahyɛ da ayɛ no mu. Mfa nnuru mmɔho abien da.
Nnuru afoforo a ebia ɛne aduru yi bedi nkitaho
Thioridazine tumi ne nnuru afoforo di nkitaho, enti ɛho hia sɛ woka nnuru a worenom nyinaa ho asɛm kyerɛ wo duruyɛfo, a vitamin ne nhabannuru ka ho.
| Nnuru a ɛnsɛ sɛ wɔde Thioridazine ka ho da | |
|---|---|
| Nnuru bi a wɔde sa koma a ɛyɛ den (te sɛ Amiodarone, Quinidine) . | Cisapride, Fluoxetine, Paroxetine, Pimozide a wɔde yɛ aduru |
| Propranolol, Pindolol, Saquinavir a wɔde di dwuma | Nnuru afoforo a ɛma QT ntam kwan kyɛ |
| Nneɛma afoforo a ebetumi de ɔhaw aba Thioridazine ho | |
| Nsaden | Nnuru a wɔde sa akisikuru ne ɔfe (Antihistamines) . |
| Aduru a wɔde sa dadwen anaa nna | Nnuru bi a wɔde sa adwenemhaw |
| Mogya mmoroso aduru | Nnuru a wɔde ko tia akisikuru (te sɛ Phenobarbital) . |
| Nnubɔne a wɔde di dwuma | Nnuru a wɔde ma obi a onnim hwee bere a wɔreyɛ oprehyɛn no |
Saa list yi nwie pɛyɛ. Enti ka nnuru, nhabannuru, ne vitamin a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo. Afei nso, sɛ wonom sigaret anaa wonom nsa a, ka kyerɛ wo duruyɛfo.
Nneɛma a ɛsɛ sɛ wode sie w’adwenem bere a worenom aduru no
- Aduruyɛ mu nhwehwɛmu: Kɔ wo duruyɛfo nkyɛn wɔ nna a wɔahyɛ ato hɔ mu kɔhwɛ wo tebea no. Sɛ wo yare no ho sɛnkyerɛnne no kɔ so anaasɛ ɛyɛ kɛse a, ka kyerɛ no.
- Dae ne adwenemhaw: Ebia saa aduru yi bɛma woate nka sɛ woda, wo tirim yɛ wo yaw, anaasɛ w’ani nhu ade yiye. Enti, kwati nneɛma a asiane wom te sɛ karka anaa mfiri a wode bedi dwuma kosi sɛ wubehu sɛnea aduru yi ka wo. Ebia adwenemhaw betumi aba bere a wosɔre gyina hɔ mpofirim anaasɛ wosɔre fi baabi a wote no. Enti, sesa gyinabea ahorow nkakrankakra. Kwati nsa a wobɛnom efisɛ tebea yi betumi asɛe kɛse.
- Nipadua mu hyew: Saa aduru yi betumi aka ɔkwan a wo nipadua no fa so di ne hyew so. Ebia worennya awɔw pii wɔ wim tebea a ɛyɛ nwini mu, na wo nipadua mu bɛyɛ hyew ntɛmntɛm wɔ wim tebea a ɛyɛ hyew mu. Enti, siesie wo ho fɛfɛɛfɛ wɔ nna a awɔw wom. Nna a ɛyɛ hyew no, hwɛ yiye wɔ owia ho, hyɛ ntade a emu yɛ hare, na nom nsu pii.
- Owia hann:Ebia saa aduru yi bɛma wo honam ani ayɛ mmerɛw kɛse wɔ owia hann ho. Enti, sɛ worekɔ owia mu a, hyɛ ntade a ɛkata wo honam ani na fa aduru a ɛbɔ wo ho ban fi owia ho di dwuma.
- Ano a ɛyɛ nwunu: Ano a ɛyɛ nwunu betumi aba. Wobetumi adi eyi so denam aduru a asikre nnim a wɔbɛwe ne nsu a wɔnom so.
- Asikreyare: Sɛ wowɔ asikreyare a, saa aduru yi betumi ama asikre dodow a ɛwɔ wo mogya mu no akɔ soro. Enti bisa wo duruyɛfo sɛ ɛsɛ sɛ woyɛ nsakrae bi wɔ w’aduan anaa wo nnuru mu anaa.
Nsunsuanso bɔne bɛn na ebia menya?
Te sɛ aduru biara no, Thioridazine betumi de ɔhaw ahorow aba. Ebi yɛ aniberesɛm, bere a afoforo nso abu so.
| Nneɛma bɔne a anibere wom a ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo no ntɛm ara | |
|---|---|
| Nneɛma a ɛma obi ho yɛ no hyew | Honam ani akisikuru, ɛyaw, anim, anofafa, tɛkrɛma anaa menewa a ɛho ahonhon. |
| Nsakrae a ɛba koma a ɛbɔ mu | Koma a ɛbɔ ntɛmntɛm anaasɛ ɛnteɛ, adwenemhaw, koko mu yaw, ahome a ɛyɛ den. |
| Neuroleptic Malignant Syndrome a Ɛyɛ Fɛ a Ɛyɛ Fɛ | Atiridiinini a ano yɛ den, ntini a ɛyɛ den, fifiri a ɛboro so, ne adwene a ɛyɛ basaa. |
| Nsɛnkyerɛnne a Ɛwɔ Akyi (EPS) . | Nipadua akwaa a wontumi nhyɛ so, wosow, ntini a ɛyɛ den, ahomegye a enni hɔ, nantew a ɛyɛ den. |
| Nsɛnkyerɛnne afoforo a anibere wom | Nsakrae a ɛba aniwa mu, ɔyare mmoawa ho sɛnkyerɛnne (atiridiinini, ɔfe, menewam yaw), adwenemhaw esiane mogya mmoroso a ɛba fam nti, akisikuru. |
| Nsunsuanso bɔne a mpɛn pii no ɛnyɛ aniberesɛm (nanso sɛ ɛkɔ so a, ɛsɛ sɛ wɔbɔ ho amanneɛ kyerɛ oduruyɛfo) . | |
| Ayamtim | Adwene a ɛyɛ basaa |
| Dae a ɛma obi da | Ano a ɛyɛ nwunu |
| Mu duru a ɛkɔ soro | |
Ɔkwan bɛn so na ɛsɛ sɛ wode aduru no sie?
Fa nnuru sie baabi a mmofra ne afieboa ntumi nkɔ hɔ . Fa sie wɔ dan mu hyew (a ɛba fam sen digrii Celsius 30), na to anoano no mu denneennen. Mfa nnuru a ne bere atwam nni dwuma na tow gu yiye.
Nkrasɛm a Wɔde Kɔ Fie
- Nnyae Thioridazine nnuru a wɔde di dwuma no nom da anaasɛ ɛnsesa dodow a wɔde ma no a wunnya wo duruyɛfo afotu.
- Ka nnuru afoforo nyinaa, vitamin ahorow, nhabannuru a wonom, ne ayaresa tebea biara a wowɔ ho asɛm kyerɛ wo duruyɛfo.
- Sɛ wunya ɔhaw biara a emu yɛ den te sɛ atiridiinini kɛse, ntini a ɛyɛ den, anaa nsakrae a ɛba koma a ɛbɔ mu a, hwehwɛ aduruyɛfo afotu ntɛm ara.
- Kwati sɛ wobɛnom nsa bere a worenom aduru yi. Hwɛ yiye kɛse bere a woreyɛ nnwuma a ɛhwehwɛ sɛ woma w’ani da hɔ te sɛ karka no.
- Sɛ wonom nnuru pii a, frɛ National Poisons Information Center ntɛm ara anaa kɔ ayaresabea Emergency Department (ETU) a ɛbɛn wo no.
👩🏽 ⚕️ Nsɛmmisa foforo (FAQs)
💬 Dɛn na wɔde Thioridazine (Thioridazine / Mellaril) aduru di dwuma?
Eyi yɛ awo ntoatoaso dedaw (Typical antipsychotic / Phenothiazine) aduru a wɔde sa adwenemyare a emu yɛ den a wɔfrɛ no ‘Schizophrenia’! Wɔmfa eyi mma obiara nnansa yi, wɔtaa de di dwuma ma ayarefo a wɔn ho yɛ den sen biara (Ayaresa-resistant) a ɛte sɛ nea wontumi nte nne a ɛyɛ nwonwa anaasɛ wontumi npere/nteɛteɛm ɛmfa ho sɛ wɔama wɔn nnuru afoforo nyinaa (anyɛ yiye koraa no nnuru 2).
💬 Adɛn nti na wɔde saa aduru yi (Thioridazine) di dwuma sɛ ‘akwan a etwa to’ nnansa yi?
Ade titiriw nti a eyi ba ne aduru yi mu nsunsuanso bɔne a ɛyɛ hu sen biara! (Adaka Tuntum Kɔkɔbɔ). Eyi betumi asakra ɔyarefo no koma mu anyinam ahoɔden nsɛnkyerɛnne (QT prolongation / Arrhythmia / Torsades de pointes) kɛse, na ama koma abɔ ntɛmntɛm mpofirim/koma atɔ ne komayare a edi awu. Enti, akyinnye biara nni ho sɛ ɛsɛ sɛ wɔn a wɔnom aduru yi yɛ ECG nhwehwɛmu na wɔhwɛ potassium dodow a ɛwɔ mogya mu daa.
💬 Koma no da nkyɛn a, nsunsuansoɔ foforɔ ne asiane bɛn na saa nnuru yi (Thioridazine) tumi de ba?
Eyi betumi asɛe aniwa no kɛse na ɛbɛtra hɔ daa. Sɛ wɔma dodow no kɔ soro a, pigmentary retinopathy betumi aba aniwa tuntum no ne retina no akyi, na ama obi ani afura na onhu ade yiye. Asiane kɛse nso wɔ hɔ sɛ obi bɛtwe ne ho akɔ akyi, ɔbɛda a ɔmfa ne ho nhyɛ mu, na nipadua/tɛkrɛma bɛtwetwe a wontumi nni so (Tardive Dyskinesia).
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