Ɛnnɛ yɛrebɛka aduru soronko bi a wɔde ma obi a ɔreko atia kokoram ho asɛm. Ebia wo duruyɛfo na ɔmaa wo anaa obi a wunim no saa aduru yi a wɔfrɛ no Vemurafenib . Enti, ɛnnɛ yɛbɛka aduru ko a eyi yɛ, sɛnea wɔde di dwuma pɛpɛɛpɛ, ne nea ɛsɛ sɛ yɛhwɛ yiye titiriw wɔ ho asɛm kɔ akyiri.
Dɛn ne aduru yi a wɔfrɛ no Vemurafenib?
Sɛ yɛbɛka no tiawa a, Vemurafenib yɛ aduru a ɛde n’ani si protein ahorow bi a ɛwɔ kokoram nkwammoaa mu so na esiw wɔn kwan. Sɛ yɛbɛka no pɛpɛɛpɛ a, ɛyɛ adwuma sɛ ayaresa a wɔde wɔn ani asi so . Wɔde sa honam ani kokoram bi a wɔfrɛ no melanoma titiriw . Wɔde sa tebea bi a ɛntaa nsi a wɔfrɛ no Erdheim-Chester yare nso .
Kae sɛ ɛtɔ mmere bi a nnuruyɛfo betumi de saa aduru yi adi dwuma wɔ tebea afoforo mu, enti sɛ wowɔ nsɛmmisa bi a, ɛbɛyɛ papa sɛ wubebisa wo duruyɛfo anaa nnuruyɛfo.
Edin a wɔtaa de frɛ saa aduru yi ne Zelboraf .
Nneɛma bɛn na ɛsɛ sɛ meka kyerɛ oduruyɛfo no ansa na mafi saa aduru yi ase?
Ansa na wubefi ase anom Vemurafenib no, ɛho hia yiye sɛ woka w’akwahosan ho abakɔsɛm kyerɛ wo duruyɛfo. Ɛho hia titiriw sɛ wobɛka akyerɛ wo duruyɛfo sɛ wowɔ tebea horow a edidi so yi mu biara a:
- Sɛ wowɔ aniwa mu nyarewa anaa aniwa mu haw a
- Sɛ wowɔ komayare a
- Sɛ woanya koma a ɛbɔ a ɛnkɔ so daa pɛn a
- Sɛ wɔadi kan ahu sɛ wo mogya mu calcium, magnesium, anaa potassium dodow sua a
- Sɛ wowɔ asaabo mu yare a
- Sɛ wowɔ mmerɛbo mu yare a
- Sɛ woanya mframa a wɔde sa yare nnansa yi anaasɛ woreyɛ mprempren a
- Sɛ woadi kan anya akisikuru anaasɛ wo ho yɛ wo hyew wɔ Vemurafenib, nnuru afoforo, nnuan, nnuru a wɔde yɛ nneɛma, anaa nneɛma a wɔde sie ho a.
- Sɛ worebɔ mmɔden sɛ wubenyinsɛn anaasɛ worenyinsɛn mprempren (eyi ho hia yiye) .
- Sɛ woyɛ ɛna a ɔma nufu (eyi nso ho hia) .
Sɛ oduruyɛfo no ka saa nneɛma yi kyerɛ wo pɛpɛɛpɛ nkutoo a, obetumi asi gyinae sɛ ebia aduru yi fata wo anaasɛ ɛnsɛ, ne ahwɛyiye a ɛsɛ sɛ woyɛ.
Ɔkwan bɛn so ankasa na mede saa aduru yi di dwuma?
Saa aduru yi ba wɔ aduruyɛ mu. Ɛsɛ sɛ wode w’ano fa nsu kuruwa biako mu. Di akwankyerɛ a ɛwɔ nnuru a wɔakyerɛw ama wo a wo duruyɛfo anaa nnuruyɛfo de ama wo no akyi.
- Mmu, nsɛe, anaa nwe saa aduru yi. Mene tablet no nyinaa.
- Wubetumi de eyi aka aduan ho anaasɛ wunhia. Nanso, sɛ wote nka sɛ wo yafunu ayɛ wo yaw a, eye sɛ wode bɛka aduan ho.
- Nom aduru no wɔ bere a ɛfata mu, dodow a wo duruyɛfo akyerɛ wo nkutoo. Mfa dodow a wɔakyerɛw ato hɔ no nnwe.
- Nea ɛho hia sen biara ne sɛ, nnyae saa aduru yi nom mpofirim a wo duruyɛfo mfa afotu mma.
- Mpɛn pii no, wɔnom nnuru yi a ɛda ntam bɛyɛ nnɔnhwerew 12. Ɛno kyerɛ sɛ sɛ wofa wɔn anɔpa a, ɛsɛ sɛ wofa dodow a edi hɔ no anadwo.
Sɛ wo nsa ka w’aduru a, nnurutɔnbea no bɛma wo akwankyerɛ nhoma titiriw bi (MedGuide) . Kenkan nhomawa yi yiye bere biara a wubenya aduru foforo. Nsɛm pii a ɛho hia ma wo wom.
Sɛ wode saa aduru yi rema mmofra a, ɛsɛ sɛ wo ne mmofra oduruyɛfo kasa fa ho na wohwɛ yiye titiriw.
Sɛ wonom nnuru pii a, dɛn na ɛsɛ sɛ woyɛ?
Sɛ wususuw sɛ woadi mfomso anom aduru yi dodo a, frɛ baabi a wɔhwɛ awuduru so anaa baabi a wɔhwɛ wɔn a wɔwɔ yare a egye ntɛmpɛ a ɛbɛn wo no ntɛm ara.
Wɔakyerɛw saa aduru yi ama wo nkutoo. Mfa nnkyɛ obi foforo biara.
Sɛ wopa nnuru dodow bi a, dɛn na ɛsɛ sɛ woyɛ?
Sɛ wopa dose bi a, fa no bere a woakae ara pɛ. Nanso, sɛ ennu nnɔnhwerew 4 kosi wo dodow a edi hɔ a woahyɛ da ayɛ ho nhyehyɛe no so a, twa dodow a woayera no so. Mmom no, fa wo dodow a edi hɔ no wɔ bere a woahyɛ da ayɛ no mu. Mfa nnuru mmɔho abien da.
Nneɛma foforo bɛn na ebetumi ne aduru yi adi nkitaho?
Eyi yɛ asɛm a ɛho hia paa. Vemurafenib betumi ne nnuru afoforo bi a worenom no adi nkitaho. Sɛ eyi ba a, nsunsuanso bɔne no betumi ayɛ kɛse anaasɛ aduru no tumi so atew.
Mfa Vemurafenib nka nnuru a edidi so yi ho:
- Cisapride na ɔkyerɛwee
- Dronedarone a wɔfrɛ no Dronedarone
- Fluconazole a wɔde ma
- Pimozide a wɔde yɛ nnuru
- Posaconazole a wɔde ma
- Saquinavir a wɔde di dwuma
- Thioridazine a wɔde ma
Bio nso, nnuru a edidi so yi betumi ne Vemurafenib adi nkitaho:
- Nnuru a wɔde ko tia HIV anaa AIDS
- Nneɛma a caffeine wom (bisa wo duruyɛfo eyi ho asɛm) .
- Nnuru bi a ekum ɔyare mmoawa, sɛ nhwɛso no: clarithromycin, erythromycin, telithromycin
- Nnuru bi a wɔde sa fungal yare, sɛ nhwɛso no: itraconazole, ketoconazole, voriconazole
- Nnuru bi a wɔde sa koma a ɛyɛ den
- Nnuru bi a wɔde sa tebea horow te sɛ akisikuru (fits), sɛ nhwɛso no: carbamazepine, phenobarbital, phenytoin
- Nnuru bi a esiw mogya a ɛtɔ anaa ɛsa, sɛ nhwɛso no: warfarin
- Nnuru a wɔfrɛ no Dextromethorphan
- Digoxin a wɔde di dwuma
- Nefazodone a wɔde yɛ nnuru
- Midazolam a wɔde di dwuma
- Nnuru afoforo a ebetumi ama koma no ayɛ nea ɛnteɛ, i.e. ɛma QT ntam kwan no kyɛ , sɛ nhwɛso no: dofetilide, ziprasidone
- Rifabutin a wɔde yɛ nnuru
- Rifampin na ɔkyerɛwee
- Rifapentine a wɔde yɛ nnuru
- Nnuadewa a wɔde ma St. John’s wort (Hypericum perforatum) .
- Tizanidine a wɔde di dwuma
Saa list yi nka nkitahodi ahorow nyinaa ho. Enti, ka nnuru (a wɔakyerɛw ama wo ne nea wɔtɔn), nhabannuru, vitamin, ne aduannuru a worenom nyinaa ho asɛm kyerɛ wo duruyɛfo. Sɛ wonom sigaret, wonom nsa, anaa wode nnubɔne a mmara mma ho kwan di dwuma a, hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo. Eyinom nso betumi ne w’aduru no adi nkitaho.
Nneɛma bɛn na ɛsɛ sɛ wohwɛ yiye wɔ ho titiriw bere a worenom aduru yi?
Ɛho hia yiye sɛ wobɛhwɛ w’akwahosan bere nyinaa bere a worenom Vemurafenib no.
- Kɔ wo duruyɛfo nkyɛn daa: Kɔ so kɔhwɛ wo sɛnea wo duruyɛfo ka kyerɛ wo no. Ebia ɛho behia nso sɛ woma wɔyɛ mogya adwuma bere a worenom aduru yi.
- Honam ani yare a emu yɛ den: Ɛtɔ mmere bi a, saa aduru yi tumi ma honam ani yare a emu yɛ den. Eyinom betumi aba bere a woafi ase anom aduru no akyi adapɛn anaa asram bi. Sɛ wunya akisikuru a ɛwɔ sɛnkyerɛnne te sɛ atiridii anaa atiridiinini a, ka kyerɛ wo duruyɛfo ntɛm ara. Ebia akisikuru no bɛdan kɔkɔɔ anaa kɔkɔɔ, afei akisikuru na honam ani betumi atutu. Anaasɛ ebia wubenya akisikuru kɔkɔɔ a w’anim anaa w’ano ho ahonhon, anaasɛ ntini a ɛho ahonhon wɔ wo kɔn anaa wo abasa mu. Sɛ wuhu biribi a ɛte sɛɛ a , ka kyerɛ wo duruyɛfo ntɛm ara.
- Ka kokoram ho asiane ho asɛm: Sɛ wonom saa aduru yi a, ebia asiane a ɛwɔ hɔ sɛ wubenya kokoram ahorow afoforo bi bɛkɔ soro. Wo ne wo duruyɛfo nka eyi ho asɛm.
- Nsakrae a ɛba w’ani so: Sɛ wuhu nsakrae bi wɔ w’ani so, te sɛ w’ani a ɛyɛ kusuu anaasɛ wohu nneɛma wɔ ɔkwan soronko so sen sɛnea wotaa hu a, ɛsɛ sɛ woka kyerɛ wo duruyɛfo ntɛm ara.
- Owia ho nkate: Eyi nso yɛ asɛm a ɛho hia yiye. Sɛ wonom Vemurafenib a, wo honam ani yɛ mmerɛw kɛse wɔ owia ho. Eyi kyerɛ sɛ bere tiaa bi mpo a wode bɛtra owia mu no betumi ama wo honam ani hyew, ayɛ kɔkɔɔ, na ayɛ kurukuruwa.
- Enti, kwati owia no sɛnea wubetumi biara.
- Sɛ ɛsɛ sɛ wokɔ owia mu a, .Hyɛ ntade a ɛkata wo honam ani yiye, hyɛ kyɛw a ano trɛw, na fa aduru pa a ɛbɔ wo ho ban fi owia ho a wo duruyɛfo kamfo kyerɛ di dwuma.
- Mfa owia akanea anaa mpa/ntanning beds nni dwuma.
- Nyinsɛn ne nufu a wɔde ma:
- Nnyinsɛn bere a worenom aduru yi ne adapɛn 2 bere a woagyae aduru no akyi.
- Sɛ woreyɛ nhyehyɛe sɛ wubenyinsɛn anaa wususuw sɛ ebia woanyinsɛn a, ka kyerɛ wo duruyɛfo ntɛm ara. Saa aduru yi betumi apira akokoaa a ɔhyɛ yafunu mu kɛse. Bisa wo duruyɛfo anaa nnuruyɛfo ma ɔmma wo nsɛm pii.
- Mma wo ba no nufu bere a worenom saa aduru yi ne adapɛn 2 bere a woagyae aduru no akyi.
Dɛn ne nsunsuanso bɔne a ebetumi afi mu aba?
Te sɛ aduru biara no, Vemurafenib betumi de nsunsuanso bɔne bi aba. Ebi yɛ aniberesɛm, ebi nso nyɛ aniberesɛm saa.
Nneɛma bɔne a ɛsɛ sɛ wobɔ wo duruyɛfo anaa akwahosan ho ɔbenfo amanneɛ ntɛm ara sɛnea wubetumi:
Sɛ wuhu saa sɛnkyerɛnne ahorow yi bi a, ka kyerɛ wo duruyɛfo a ɛnntwentwɛn wo nan ase sɛ:
- Nneɛma a ɛma obi ho yɛ no hyew: honam ani akisikuru, ɛyaw anaa akisikuru, anim, anofafa anaa tɛkrɛma a ɛho ahonhon
- Ɔhome a ɛyɛ den
- Anisoadehu sesa
- Nsu a ne kɔla yɛ tuntum
- Aniwa mu yaw anaasɛ ɛho ahonhon
- Koma a ɛbɔ ntɛmntɛm anaasɛ ɛnteɛ daa
- Ɔtotɔ piti, adwenemhaw, ne asehwe
- Nnipa a wɔn ho nyɛ wɔn hyew wɔ ɔkwan a ɛkɔ akyiri so anaasɛ sɛnkyerɛnne ahorow a ɛte sɛ atiridii
- Nsu a wɔde kɔla yɛ hann
- Akɔnnɔ
- Nwansena foforo bi pue; honam ani akisikuru anaa kɔkɔɔ a mogya tu anaasɛ ɛnsa; nsakrae a ɛba wɔ akisikuru anaa nsensanee kɛse anaa ne kɔla mu
- Ɛyaw, akisikuru, anaa nkate a ɛyera wɔ akwaa no mu
- Akisikuru, atiridiinini, ne akyi a ɛho ahonhon
- Wora a ɛyɛ kɔkɔɔ, akisikuru, honam ani a ɛrepaapae (a honam ani a ɛrepaapae wɔ ano ka ho) .
- Ɛyaw a ɛba yafunu no atifi nifa so
- Owia ho nkate anaa owia a ɛhyew
- Wora a ɛyɛ den wɔ nsateaa ne nan ase
- Nsateaa kotow kɔ mu na ɛyɛ den
- Sɛ́ wobɛte nka sɛ woayɛ mmerɛw anaasɛ woabrɛ wɔ ɔkwan soronko so
- Ɔfe a wɔfe
- Aniwa anaa honam ani a ɛyɛ kɔkɔɔ
Nneɛma bɔne a mpɛn pii no enhia sɛ wokɔ ayaresabea (sɛ eyinom kɔ so anaasɛ ɛhaw adwene a, ka kyerɛ wo duruyɛfo):
- Nneɛma a ɛyɛ dɛ sesa
- Aduan ho akɔnnɔ a ɛyera
- Ɔyare a ɛma obi dwensɔ (yafunu mu yaw) .
- Adwene a ɛyɛ basaa
- Wora a ɛyɛ nwunu
- Nwi a ɛtɔ
- Tipaeɛ
- Nkwaa mu yaw
- Ntini mu yaw
- Akisikuru (te nka sɛ ɔyare) .
- Ankles, nan, nsa a ɛho ahonhon
- Ɔbrɛ
Saa nsɛm a wɔahyehyɛ yi nka nsunsuanso bɔne a ebetumi aba nyinaa ho. Sɛ wuhu sɛnkyerɛnne foforo biara a ɛyɛ soronko a, kɔ wo duruyɛfo nkyɛn. Sɛ wopɛ a, wubetumi nso abɔ FDA (Food and Drug Administration) amanneɛ denam 1-800-FDA-1088 a wobɛfrɛ so.
Ɔkwan bɛn so na ɛsɛ sɛ mede saa nnuru yi sie?
- Fa sie baabi a mmofra ntumi nkɔ hɔ. Eyi ho hia paa.
- Fa sie wɔ dan mu hyew (a ɛwɔ digrii Celsius 20 kosi 25 / digrii Fahrenheit 68 ne 77 ntam).
- Fa aduru no sie mfitiase toa a ɛbaa mu no mu, na to mu denneennen.
- Tow nnuru a ne bere atwam a womfa nni dwuma.
Nea etwa to no, nneɛma a ɛsɛ sɛ wokae (Take-Home Message) .
Vemurafenib yɛ aduru a edi dwuma titiriw wɔ kokoram ayaresa mu. Nneɛma kakraa bi wɔ hɔ a ɛsɛ sɛ wohwɛ yiye bere a wode redi dwuma no.
- Di oduruyɛfo no akwankyerɛ akyi pɛpɛɛpɛ. Yɛ biribiara sɛnea ɔka kyerɛ wo no pɛpɛɛpɛ, a bere a ɛsɛ sɛ wonom aduru no, dodow, ne ɔkwan a wobɛfa so agyae nom ka ho.
- Ka nnuru afoforo a wonom nyinaa ne nyarewa foforo biara a wowɔ ho asɛm kyerɛ wo duruyɛfo. Eyi bɛboa ma wɔasiw nsunsuanso bɔne ano.
- Sɛ wuhu sɛnkyerɛnne foforo biara, titiriw honam ani nsakrae anaa nsakrae a ɛba w’ani so a, ka kyerɛ wo duruyɛfo no ntɛm.
- Hwɛ yiye wɔ owia ho. Mma wo werɛ mmfi eyi.
- Sɛ woanyinsɛn, woreyɛ nhyehyɛe anyinsɛn, anaa worema nufu a, hwɛ hu sɛ wobɛka akyerɛ wo duruyɛfo ansa na woanom aduru yi.
Saa asɛm yi yɛ nsɛm a wɔaboaboa ano wɔ ɔkwan a ɛkɔ akyiri so ara kwa. Sɛ wowɔ nsɛmmisa foforo biara fa saa aduru yi ho a, yɛsrɛ wo ntwentwɛn wo nan ase sɛ wubebisa wo duruyɛfo, nnuruyɛfo, anaa akwahosan ho ɔyaresafo foforo. Wɔbɛtumi aboa wo.
Yɛpɛ sɛ monya nkɔsoɔ nyinaa wɔ w’akwahosan akwantuo no mu!
` Vemurafenib, Zelboraf, kokoram aduru, honam ani kokoram, melanoma, nea efi mu ba, aduru, kokoram ayaresa
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