N tun b’a miiri ko kɔnɔdimi don, nka yala nin ye GIST kansɛri ye wa? (Kɔnɔnatumuw ka sɔgɔsɔgɔninjɛ) .

Yala tuma dɔw la, kɔnɔdimi dɔrɔn de bɛ i la wa? Walima, yala i bɛ sɛgɛn cogo la min tɛ deli ka kɛ, kun kɛrɛnkɛrɛnnen tɛ min na wa? Laala aw hakili la ko a bɛ tali kɛ aw ka dumuni na nin donw in na, walima a bɛ se ka kɛ kɔnɔboli ye. O de bɛ se ka kɛ a fanba la. Nka, hali ni a man ca, o taamasiɲɛw bɛ se ka kɛ fana kansɛri taamasiɲɛ ye min man teli ka sɔrɔ, a man ca. An bɛna kuma o de kan bi. O ye GIST ye, walima kɔnɔbara basigilen sɔgɔsɔgɔninjɛ. Aw kana siran n’aw ye tɔgɔ mɛn, an bɛna kuma fɛn bɛɛ kan cogo nɔgɔman na ani cogo jɛlen na.

N’an y’a fɔ cogo nɔgɔman na, nin GIST in ye mun ye?

GIST kɔrɔ ye kɔnɔbara basigilen tumu ye . An ka nin kumaw tiɲɛ.

• Kɔnɔnatumu : O bɛ tali kɛ an ka dumunikɛminɛnw na. O kɔrɔ ye ko an bɛ dumuni min dun, o bɛ tɛmɛ sira min fɛ - da, dumunikɛminɛn, kɔnɔbara, banakɔtaa fitini, ani banakɔtaa.
• Stromal : O bɛ tali kɛ farikolo yɔrɔ kɛrɛnkɛrɛnnen dɔ la min bɛ sɔrɔ an farikolo yɔrɔw kogow la, wa a bɛ kɛ o farikolo yɔrɔw dɛmɛnan ye.
• Tumu: N’a sɔrɔ i ye nin kelen in mɛn. O kɔrɔ ye ko kuru dɔ don.

N’an y’a fɔ cogo nɔgɔman na, GIST ye kansɛribana ye min bɛ daminɛ farikolokisɛ suguya kɛrɛnkɛrɛnnen dɔ la min bɛ an ka dumunikɛcogo yɔrɔ dɔ kogo la (a ka ca a la kɔnɔbara walima banakɔtaa fitini).

Nin ye kansɛri suguya ye min man teli ka sɔrɔ, a bɛ sɔrɔ farikolo yɔrɔ nɔgɔlenw (sarcomes) kulu la. An ka banakɔtaa kogow la, farikolokisɛ kɛrɛnkɛrɛnnenw bɛ yen minnu bɛ wele ko ``Cajal ka selilu cɛmancɛw.`` Aw ye miiri o farikolokisɛw la i n’a fɔ an ka banakɔtaa taamasiɲɛw. O farikolokisɛw bɛ dɛmɛ ka sɔgɔsɔgɔninjɛw kunbɛn minnu ka kan ka kɛ walasa ka dumuni gɛlɛya banakɔtaa fɛ. GIST kuruw bɛ sɔrɔ ni fiɲɛ dɔ bɛ o farikolokisɛw la, o bɛ kɛ sababu ye ka u tila ɲɔgɔn na cogo min tɛ se ka kunbɛn.

O kurukuru ninnu bɛ se ka dɔgɔya tuma dɔw la i n’a fɔ kretiɛnw ka fɛnɲɛnamafagalan. Ni u ka dɔgɔn, u bɛ se ka to yen san caman kɔnɔ ka sɔrɔ u ma taamasiɲɛ foyi jira. Nka, kuru dɔw bɛ bonya dɔɔni dɔɔni ka taamasiɲɛw daminɛ minnu bɛ dusukasi bila an na.

GIST taamasiɲɛ minnu bɛ se ka kɛ, olu ye jumɛnw ye?

A ka ca a la, o kuru ninnu bɛ sɔrɔ a danma sɛgɛsɛgɛli walima opereli senfɛ min kɛra kun wɛrɛ la, taamasiɲɛ foyi tɛ u la. Nka ni bana taamasiɲɛw kɛra, u bɛ se ka kɛ nin cogo la. An k' u bila tabali dɔ kɔnɔ min faamuyali ka nɔgɔn .

Mun na nin GIST in bɛ yiriwa? O sababu ye mun ye?

A ka c’a la, GIST sababuba ye an ka jamu dɔ yeli ye. Miiri jamu minnu bɛ an farikolo la, olu ye cikan gafe ye walasa an farikolo ka bonya ani ka baara kɛ. Ɲɛ dɔ bɛ nin kalan gafe in kɔnɔ min tɔgɔ ye ko `(KIT gene)`. Ka Kɛɲɛ ni cikanw ye minnu bɛ nin ɲɛ in kan, seli minnu bɛ Weele ko `(Cajal ka seliw cɛmancɛ)` an ye minnu Fɔ ka Tɛmɛ olu bɛ Dabɔ ka Kɔrɔsi.

Nka tuma dɔw la, sɛbɛnni walima daɲɛ dɔ bɛ sɛbɛn cogo jugu la nin `(KIT gene)` ɲɛ in kan. A bɛ iko sɛbɛnni fili. Furakɛcogo la, o bɛ wele ko `(mutation)`. O fili in kosɔn, KIT jamu bɛ cikan juguw di walasa ka farikolojɔlifɛn kɛrɛnkɛrɛnnen dɔ dilan min bɛ wele ko `(KIT CD117)`. O farikolojɔlifɛn jugu in kosɔn, o farikolokisɛw bɛ taamasiɲɛ sɔrɔ tuma bɛɛ ko "ka to ka tila, ka to ka tila." O waati de la o farikolokisɛw bɛ bonya u yɛrɛ ma, ka kɛ kuru ye.

O fɛn caman Changements genetiques (Yɛlɛma) bɛ kɛ tuma caman na an ka ɲɛnamaya kɔnɔ. O kɔrɔ ye ko u tɛ fɛn ye an bangera ni min ye.

Nka, a man teli kosɛbɛ, nin bana in bɛ se ka jɛ ni jamu cogoyaw ye minnu bɛ bɔ mɔgɔw la ka taa mɔgɔw la. O ko dɔw ye ninnu ye:

• Denbaya ka GIST bana : Nin ye bana ye min man teli ka sɔrɔ. O cogo la, den bɛ KIT jamu nafama ciyɛn ta bangebaga kelen fɛ. O cogo la, GIST kuruw bɛ se ka bɔ u denmisɛnman, walima kuru caman bɛ se ka sɔrɔ.
• Neurofibromatose type 1 : Nin fana ye bana ye min bɛ sɔrɔ jamu fɛ. A bɛ kɛ sababu ye ka kurukuruw sɔrɔ farikolo nɛrɛmuguma kɔnɔ. Nin bana in bɛ mɔgɔ minnu na, olu ka GIST sɔrɔli farati ka bon dɔɔni ka tɛmɛ jamanaden bɛɛ kan.
• Carney-Stratakis syndrome : Nin fana ye bana ye min man ca kosɛbɛ, a bɛ sɔrɔ cɛya la. Nin bana in bɛ mɔgɔ minnu na, olu fana farati ka bon GIST sɔrɔli la.

Dɔgɔtɔrɔw bɛ GIST sɛgɛsɛgɛ cogo di?

Ni aw taara dɔgɔtɔrɔso la ni bana taamasiɲɛ minnu fɔra sanfɛ, a bɛ fɔlɔ ka aw ɲininka aw ka bana taamasiɲɛw la. U bɛ yen kabini waati jumɛn, u dusukunnataw, a ɲɔgɔnnaw O kɔfɛ, a bɛna i sɛgɛsɛgɛ. Ka fara o kan, a bɛna sɛgɛsɛgɛli caman kɛ walasa ka bana in sababu tigitigi dɔn .

Sɛgɛsɛgɛli kunbabaw kɛra

• Sanfɛla endoskopi : A ka ca a la nin ye sɛgɛsɛgɛli fɔlɔ ye min bɛ kɛ. N’an y’a fɔ cogo nɔgɔman na, tubabukan na, kamera fitinin dɔ sirilen bɛ a la, o bɛ don da kɔnɔ ka dumunikɛminɛn, kɔnɔbara ani banakɔtaa yɔrɔ fɔlɔ sɛgɛsɛgɛ. O bɛ se ka kurukuruw ni joli bɔli lajɛ k’a ɲɛsin a yɛrɛ ma.
• CT scan: O bɛ an farikolo kɔnɔna ja tigɛlenw ta. A bɛ i n'a fɔ buruburu tigɛlen. O bɛ se ka kuru bonya jira ka jɛya, a sigiyɔrɔ, ani ni a jɛnsɛnna farikolo yɔrɔ wɛrɛw la, i n’a fɔ sugunɛ.
• Biopsie (Biopsie) : 1 .Nin ye sɛgɛsɛgɛli ye min nafa ka bon kosɛbɛ walasa ka bana in sɛgɛsɛgɛ waati 100%. Endoskopi walima fɛɛrɛ wɛrɛ senfɛ, farikolo yɔrɔ fitinin dɔ bɛ bɔ tumu sikɛlen na. O kɔfɛ, farikolo yɔrɔ bɛ sɛgɛsɛgɛ ni mikroskɔpu ye laboratuwari kɔnɔ walasa k’a dɔn ni GIST selilɛriw don.
• PET scan : Tuma dɔw la, kɛrɛnkɛrɛnnenya la ni siga bɛ a la ko kansɛri jɛnsɛnna farikolo yɔrɔ wɛrɛw la, o sɛgɛsɛgɛli bɛ se ka kɛ.

GIST furakɛcogo jumɛnw bɛ yen?

GIST furakɛli bɛ bɔ kuru bonya la, a sigiyɔrɔ la, ani ni a jɛnsɛnna yɔrɔ wɛrɛw la. Furakɛli suguya fila de bɛ yen.

1. Opereli kɛli:

A ka ca a la, GIST kuruw furakɛcogo ɲuman ye ka kuru bɔ pewu ni opereli ye. Ni kuru ka dɔgɔn, ni a ma jɛnsɛn yɔrɔ wɛrɛw la, opereli dɔrɔn bɛ se ka bana in furakɛ pewu.

2. Furakɛli min ɲɛsinnen don a ma:

Nin ye fɛn ye min bɛ fɛn caman sɛmɛntiya GIST furakɛli la. O furaw tɛ i n’a fɔ chimiothérapie basigilen, u bɛ i n’a fɔ “bɔnbu hakilitigiw”. U bɛ KIT poroteyini nafama min kofɔ ka tɛmɛ, u bɛ o de laɲini k’a ɲɛsin u yɛrɛ ma. O la, tiɲɛni ka dɔgɔn kosɛbɛ farikolokisɛ kɛnɛmanw na.

• Sani opereli ka kɛ : Ni kuru ka bon kosɛbɛ ani ni opereli ka gɛlɛn, o furakɛli laɲininen in bɛ kɛ fɔlɔ ka sɔrɔ opereli bɛ kɛ kuru dɔgɔyalen kɔfɛ.
• Opereli kɔfɛ: Ni farati bɛ bana in ka segin opereli kɔfɛ, o fura ninnu fana bɛ di walasa ka dɔ bɔ o farati la.
• Ni kansɛri jɛnsɛnna: Ni kuru jɛnsɛnna kojugu fo a tɛ se ka bɔ, a bɛ se ka kɛ aw ka kan ka fura ninnu ta aw si bɛɛ la walasa ka bana in kunbɛn ani ka dɔ bɔ a taamasiɲɛw la.

Aw bɛ se ka mun makɔnɔ ni aw bɛ balo ni GIST bana ye?

Furakɛli kɔfɛ, a taamasiɲɛw bɛ se ka ɲɛ, wa tuma dɔw la, bana bɛ se ka kɛnɛya pewu. Nka, GIST ye bana ye min bɛ se ka segin. O la, a nafa ka bon kosɛbɛ ka to ka kuma aw ka kansɛri dɔgɔtɔrɔ fɛ min bɛna aw ladon hali furakɛli kɔfɛ.

Aw bɛna tugu-tugu ɲɔgɔn kɔ ni aw ka dɔgɔtɔrɔ ye kalo 3 o kalo 3 fo kalo 6 o kalo 6. O waatiw la, sɛgɛsɛgɛliw bɛna kɛ walasa ka segin taamasiɲɛw lajɛ.

• `CT scans`
• `MRI sɛgɛsɛgɛliw`
• `PET sɛgɛsɛgɛliw`

An bɛ sɛgɛsɛgɛliw kɛ i n’a fɔ nin walasa ka a dɔn ko fɛn bɛɛ bɛ ka ɲɛ.

Ikomi GIST ye bana ye min man teli ka sɔrɔ, a ka ca a la, i bɛ kabakoya ani ka siran ni i y’a dɔn. Nka aw hakili to a la ko sisan, fura minnu bɛ se ka kɛ kosɛbɛ nin bana in na. I kelen tɛ. I ka dɔgɔtɔrɔso jɛkulu, i somɔgɔw ani i teriw bɛɛ bɛ yen walasa k’i dɛmɛ. Aw bɛ bana in dɔn, ka ɲininkaliw kɛ, ka furakɛli kunbɛn cogo ɲuman na.