Mina míanya nu tso wò CK ƒe sesẽme ŋu. Nukae nye Creatine Kinase (CK) sia?

Ɣeaɖewoɣi ne èyi ɖɔkta gbɔ la, ebiana tso asiwò be nàdo ʋu aɖewo kpɔ, alo? Wo dometɔ ɖekae nye dodokpɔ sia si woyɔna be CK. Eyata, ne ame geɖe se nya sia la, biabia sue aɖe vaa susu me na wo be, "Nukae nye CK sia?" "Nukatae woléa ŋku ɖe esia ŋu?" Mègatsi dzi o, egbea míaƒo nu tso CK sia, si tsi tre ɖi na Creatine Kinase, ŋu le mɔ bɔbɔe aɖe si gɔme nàte ŋu ase nu.

Nukae nye creatine kinase (CK)?

Kpuie ko la, CK nye enzyme . Enzyme nye protein ƒomevi aɖe si naa atike vovovowo ƒe dɔwɔwɔ kabakaba eye wòkpena ɖe mía ŋu le míaƒe ŋutilã me. CK enzyme sia le wò dzi ƒe lãmeka me koŋ (si fia be lãmeka siwo le wò dzi me), lãmeka siwo kpe ɖe wò ƒuwo ŋu (míeyɔa esiawo be `ƒumelãwo`, si fia be lãmeka siwo kpena ɖe ŋuwò nèʋuʋua wò abɔwo kple afɔwo eye nèzɔna), eye agbɔsɔsɔ sue aɖe ŋutɔ le ahɔhɔ̃a me .

Eyata ne nane gblẽ le lãmeka siawo, si fia dzitodzito, ƒumelã, alo ahɔhɔ̃mekawo ŋu la, lãmenugbagbevi mawo gblẽna eye emenuwo dona. Ɣemaɣie CK enzyme sia dona ɖe ʋua me. Zi geɖe la, CK ƒe agbɔsɔsɔ sue aɖe ŋutɔ si le míaƒe ʋu me la tsoa ƒunukpeƒeŋusẽ mawo gbɔ.

Tsɔe be ède kame vevie ŋutɔ. Ekema wò lãmekawo ate ŋu agblẽ vie. Le ɣeyiɣi mawo me la, CK ƒe agbɔsɔsɔ ate ŋu adzi ɖe edzi le ʋua me hã. Azɔ hã, ne lãmekawo ƒe dɔlélewo li (`Myopathies`), le kpɔɖeŋu me, amesiwo ŋu dɔlélewo abe `Muscular Dystrophy` le hã ƒe CK ƒe agbɔsɔsɔ dzina ɖe edzi.

Ðe CK ƒe enzyme ƒomevi aɖewo lia?

Ẽ, CK enzyme sia ƒomevi vevi etɔ̃e li. Abe nɔvi siwo le ƒome aɖe me ene la, ƒomevi ɖesiaɖe le míaƒe ŋutilã ƒe akpa vovovowo:

• CK-MM: Esia ƒomevi bɔ ɖe wò ƒunukpeƒeŋusẽwo me wu .
• CK-MB: Esia ƒe akpa gãtɔ le wò dzi ƒe lãmeka me .
• CK-BB: Esia ƒomevi bɔ ɖe ahɔhɔ̃mekawo me wu .

Ele vevie be nànya ƒomevi siawo, elabena ne CK ƒe agbɔsɔsɔ dzi ɖe edzi la, ne èlé ŋku ɖe CK ƒomevi si dzi ɖe edzi ŋu la, àte ŋu akpɔ afisi wògblẽ nu le le ŋutilãa me ƒe susu si me kɔ.

Eyata nukae nye creatine kinase (CK) dodokpɔa?

Creatine kinase (CK) dodokpɔ dzidzea CK ƒe agbɔsɔsɔ le wò ʋu me . Dodokpɔ sia ate ŋu anya ne wò CK ƒe agbɔsɔsɔme sɔ gbɔ wu alesi wòle dzɔdzɔmee. Ne ele nenema la, ate ŋu afia be nu gblẽ le wò ƒunukpeƒewo, dzi, alo ahɔhɔ̃ ŋu alo kuxi aɖe le eŋu. Nusiwo gblẽ sia ate ŋu anye ɣeyiɣi kpui aɖe (si nu sẽ) alo ɣeyiɣi didi (si nɔa anyi didi).

Wogayɔa CK dodokpɔ sia be:

• CK ƒe ƒuƒoƒo
• CK creatine si wotsɔna ƒoa ƒui
• Phosphokinase CPK ƒe dɔwɔwɔ

Dɔ kae nye creatine kinase (CK) enzyme ƒe dɔwɔwɔ?

Nu vevi aɖee nye esi. Kadodo boo aɖeke mele CK enzyme ƒe dɔwɔwɔ nyuie kple nusi wògblɔna ne CK ƒe agbɔsɔsɔ sɔ gbɔ le ʋua me dome o. Dɔ ŋutɔŋutɔ si CK enzyme wɔnae nye be wòatsɔ phosphate ƒe ƒuƒoƒo aɖe akpe ɖe nusi woyɔna be creatine ŋu le míaƒe lãmekawo me. Creatine nye nane si kpena ɖe lãmekawo ŋu be ŋusẽ nado. Eyata ne CK enzyme tsɔ phosphate kpe ɖe creatine sia ŋu la, eva zua molecule si me ŋusẽ geɖe le si woyɔna be phosphocreatine . Míaƒe ŋutilã zãa phosphocreatine sia tsɔ wɔa ŋusẽ.

Eyata ne wò lãmekawo, dzi, alo ahɔhɔ̃ gblẽ la, lãmenugbagbevi mawo gblẽna. Emegbe CK enzyme si le lãmenugbagbevi mawo me, kpakple nu bubuwo dona ɖe ʋua me. Aleae CK ƒe agbɔsɔsɔ si le ʋua me dzina ɖe edzii. Ema fia be CK ƒe agbɔsɔsɔ dzina ɖe edzi, menye le eƒe dɔwɔwɔ nyuie ta o, ke boŋ le esi lãmenugbagbeviawo gblẽ eye CK dona ɖe ʋua me ta.

Nukae wozãa CK dodokpɔwo na?

Zi geɖe la ɖɔktawo zãa CK dodokpɔa tsɔ dia lãmekawo ƒe kuxiwo heléa ŋku ɖe wo ŋu . Ema fia be:

• Lãmetsiwo ƒe dɔlélewo (`Lãmetsiwo ƒe dɔlélewo` / `Myopathies`): Esiawo ƒe kpɔɖeŋuwoe nye:
• Duchenne muscular dystrophy (DMD): Esia nye dɔléle si mebɔ o, si ƒe dome míenyi, si nana ƒumeŋuɖuiwo gbɔdzɔna, wogbãna, eye womegawɔa dɔ o. Zi geɖe la, edzea ŋutsuviwo dzi.
• Rhabdomyolysis: Esia nye nɔnɔme si me lãmekawo gblẽna kabakaba ŋutɔ. Esia ate ŋu atso abi gã aɖe, lãmekawo ƒe dɔléle, alo nɔnɔme bubu aɖe gbɔ.
• Lãmetsiwo ƒe abi: Esiawo ate ŋu anye:
• Lãmetsiwo ƒe tete, tete, vuvu, alo hehe le afɔku alo kamedede si gbɔ eme ta.
• Dzobibi siwo le dzidzenu etɔ̃lia me.
• Elektrikŋusẽ ƒe ʋuʋu.
• Lãmetsiwo ƒe dɔléle (Myositis): Esia ƒe kpɔɖeŋu aɖewoe nye:
• Polymyositis: Esia nye dɔdzẽ ƒe dɔléle si nana lãmekawo gbɔdzɔna. Zi geɖe la, egblẽa nu le lãmeka siwo te ɖe ŋutilãa ƒe akɔta ŋu.
• Dermatomyositis: Esia nye dɔléle si mebɔ o si nana lãmekawo gbɔdzɔna eye ŋutigbalẽ gblẽna.
• Pyomyositis: Esia nye dɔlékui si mebɔ o si xɔa lãmekawo. Zi geɖe la, ehea ʋuʋudedi vɛ.

Esi wònye be lãmekawo ƒe dzesiwo ate ŋu anye nɔnɔme bubu geɖe ƒe dzesiwo ɣeaɖewoɣi ta la, wò ɖɔkta ate ŋu aɖe gbe be woawɔ dodokpɔ bubu geɖe kpe ɖe CK dodokpɔa ŋu. Le kpɔɖeŋu me:

• Elektrik-nu siwo wotsɔna ƒoa nuwoe
• BUN (ʋu me urea nitrogen) .
• Creatinine si wotsɔ wɔa dɔe
• Myoglobin si le aɖuɖɔ me

CK dodokpɔwo kple dzi ƒe dɔmawɔmawɔ nyuie

Tsã la, wozãa CK dodokpɔ tsɔ dea dzesi dzidɔ. Gake fifia ƒã hafi wowɔa esia. Elabena fifia wozãa Troponin.Dodokpɔ bubu aɖe li si woyɔna be troponin, si nyo wu CK le dzi ƒe gbegblẽ kpɔkpɔ me. Esia tae fifia, zi geɖe la, ne wosusu be dzidɔ le ame ŋu la, troponin ye nye dodokpɔ si wokpɔna.

Nukatae wòhiã be woawɔ CK dodokpɔ?

Ne lãmekawo ƒe dɔmawɔmawɔ nyuie ƒe dzesiwo le ŋuwò la, wò ɖɔkta ate ŋu abia be woawɔ CK dodokpɔ. Dzesi siawo dometɔ aɖewoe nye:

• Lãmetsiwo ƒe vevesese kple/alo lãmekawo ƒe sesẽ.
• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ.
• Kuxi siwo le ŋutilã ƒe dadasɔ ŋu.
• Nu ƒe ʋuʋu alo ʋuʋudedi ƒe seselelãme.
• Aɖuɖɔ si ƒe amadede nye viviti (abe ɣi ene).

Azɔ hã, ne lãmekawo xɔ abi alo ʋusɔgbɔdɔ le ŋuwò kpɔ la, ahiã hã be woawɔ dodokpɔ sia ɣemaɣi. Le abi aɖewo me la, ate ŋu axɔ ŋkeke eve hafi CK ƒe agbɔsɔsɔ naɖo eƒe kɔkɔƒe. Eyata ɖewohĩ ahiã be nàna woawɔ dodokpɔ sia wu zi ɖeka.

Amekae wɔa CK dodokpɔa?

Zi geɖe la, lãmesẽdɔwɔla aɖe si woyɔna be phlebotomist ye xɔa ʋu, si nye ʋu si woatsɔ awɔ CK dodokpɔ. Gake lãmesẽdɔwɔla ɖesiaɖe si wona hehee be wòano ʋu ate ŋu awɔ esia. Emegbe woɖoa ʋua ɖe dodokpɔxɔ aɖe me. Afimae atikewɔlawo ƒe nudokpɔƒe ƒe dzɔdzɔmeŋutinunyala aɖe dzraa kpɔɖeŋua ɖo eye wòtsɔa numekulawo donɛ kpɔna .

Aleke mawɔ adzra ɖo ɖe CK dodokpɔa ŋu?

Zi geɖe la, naneke meli si wòle be nàwɔ atsɔ adzra ɖo koŋ ɖe CK ʋudodokpɔ ŋu o.

Gake ne wò ɖɔkta le se dem be yeado CK dodokpɔ sia be yeatsɔ adi lãmeka me kuxi aɖewo la, ele be nàɖo seɖoƒe na wò kamedede sesẽ le ŋkeke siwo do ŋgɔ na dodokpɔa me. Esia le alea elabena kamedede hã ate ŋu ana lãmekawo nate ɖeɖi ame ŋu hena ɣeyiɣi aɖe, si ate ŋu ana CK ƒe agbɔsɔsɔ nadzi ɖe edzi le ʋua me. Eyata, wɔ wò dɔwɔna siwo nèwɔna ɖaa ko.

Nukae nàkpɔ mɔ na ne wole CK ʋudodokpɔ wɔm?

Esiae dzɔna ne èdo ʋu:

1. Ànɔ zikpui dzi. Lãmesẽdɔwɔla la akpɔ ʋuka si me ʋu le bɔbɔe le wò alɔnu. Zi geɖe la, wotiaa ʋuka aɖe le wò abɔ ƒe akpa si le eme, le axa si tsi tre ɖe wò abɔta ŋu.

2. Ne wonya ke ɖe ʋukaa ŋu ko la, wokɔa teƒea ŋu eye wotsɔa dɔlékuiwutike dea eme.

3. Emegbe, wotsɔa aŋe sue aɖe dea ʋuka ma me eye woɖea ʋu. Le ɣeyiɣi sia me la, àte ŋu ase le ɖokuiwò me abe anyidi sue aɖe ɖu ye ene.

4. Ne wotsɔ aŋea de eme vɔ la, woaƒo ʋu vi aɖe nu ƒu ɖe dodokpɔmɔ̃ me.

5. Ne woɖe ʋua vɔ la, woɖea aŋea ɖa eye wotsɔa kotoku alo gaze kakɛ aɖe dana ɖe teƒea eye wotsɔa nyaƒoɖeamenu dea edzi be ʋua natɔ te.

6. Emegbe wotsɔa aŋɔ ƒoa teƒea. Emae nye ema.

Dɔwɔwɔ sia katã mexɔa aɖabaƒoƒo atɔ̃ o.

Nukae dzɔna le CK dodokpɔa megbe?

Ne woɖe wò ʋu vɔ la, woɖonɛ ɖe nudokpɔƒe. Ne wonya do dodokpɔa me tsonu ko la, wò ɖɔkta ana nànya dodokpɔa me tsonuawo.

Ðe afɔku aɖewo le CK ʋudodokpɔ mea?

Ʋudodokpɔ nye atikewɔwɔ me dodokpɔ si bɔ ŋutɔ, si hiã. Afɔku gã aɖeke mele ʋudodo me o . Àte ŋu ase veve vie alo abi le afisi woɖe ʋua le. Gake ema anyo kaba.

Ɣekaɣie manya CK dodokpɔa me tsonu?

Zi geɖe la, ele be nàxɔ wò CK dodokpɔa me tsonu le ŋkeke ɖeka alo eve me , gake ɣeaɖewoɣi la, ate ŋu axɔ ɣeyiɣi didi wu.

Nukae CK dodokpɔ me tsonu gblɔ na mí?

Zi geɖe la, nyatakaka siawo nɔa ʋudodokpɔ ŋuti nyatakaka, si nye CK dodokpɔ ƒe nyatakaka, me:

• Ʋudodokpɔa ƒe ŋkɔ, alo nusi wodzidze le wò ʋu me.
• Wò ʋudodokpɔ me tsonu ƒe xexlẽme alo dzidzenu.
• Dzidzenu si sɔ na dodokpɔ ma.
• Nyatakakawo abe nenye be wò emetsonua sɔ, mesɔ o, kɔkɔ, sue, nyui, alo vɔ̃ ene.

Nukae nye creatine kinase (CK) ƒe agbɔsɔsɔ si sɔ?

CK ƒe agbɔsɔsɔ si sɔ le ame tsitsi si le lãmesẽ me ate ŋu ato vovo le nu geɖe nu:

• Wò ŋutsu alo nyɔnu nyenye .
• Wò duɖimekeke .
• Wò dɔwɔna ƒe seƒe (si nye kamedede kple kamedede ƒe agbɔsɔsɔme si nèwɔna).

Azɔ hã, dometsotso siawo siwo sɔ ate ŋu ato vovo le dodokpɔmɔnu siwo dodokpɔxɔ ɖesiaɖe zãna nu. Eyata lé ŋku ɖe nufiame ƒe didime si wona le wò dodokpɔxɔ ƒe nyatakaka me ŋu ɣesiaɣi. Le mamã dedie nu la, ŋutsuwo ƒe CK sɔ gbɔ vie wu nyɔnuwo.

Ame siwo ƒe lãmekawo sɔ gbɔ (i.e., amesiwo ƒe ŋutilã me ami sɔ gbɔ) hã ate ŋu akpɔ CK ƒe agbɔsɔsɔ si sɔ gbɔ wu ame bubuwo.

Nukae creatine kinase (CK) ƒe agbɔsɔsɔ si sɔ gbɔ fia?

Ne wò CK ƒe agbɔsɔsɔme sɔ gbɔ, alo ne wò CK ƒe agbɔsɔsɔ dzina ɖe edzi ɣesiaɣi le CK dodokpɔ siwo wowɔna enuenu me la, zi geɖe la, efia be lãmeka aɖe gblẽ le ŋuwò nyitsɔ laa. Gake CK dodokpɔ ɖeɖe mate ŋu anya lãmeka si tututu gblẽ, alo nusi na wògblẽ o.

Vevietɔ: Mègatsi dzodzodzoe ne wò CK ƒe agbɔsɔsɔ dzi ɖe edzi o. Ðewohĩ ahiã be wò ɖɔkta nawɔ dodokpɔ geɖe wu be wòake ɖe nusi gbɔ wòtso ŋu.

Zi geɖe la, ɖɔktawo wɔa CK dodokpɔ vovovowo tsɔ kpɔa alesi wò CK ƒe agbɔsɔsɔ le tɔtrɔme. Ne wò CK ƒe agbɔsɔsɔ ɖo eƒe kɔkɔƒe eye emegbe wòɖiɖi vivivi la, ekema efia be wò lãmekawo ƒe gbegblẽ dzi le ɖeɖem kpɔtɔ. Gake ne wò CK ƒe agbɔsɔsɔ yi edzi le dzi yim, alo gakpɔtɔ le kɔkɔm la, ate ŋu afia be èle lãmekawo ƒe gbegblẽ alo lãmekawo ƒe gbegblẽ atraɖii me tom.

Ne wò dɔwɔwɔ me tsonu ɖee fia be wò CK ƒe agbɔsɔsɔ sɔ gbɔ wu alesi wòle dzɔdzɔmee la, wò ɖɔkta ate ŋu abia be woado CK enzyme ƒomevi siwo meyɔ va yi (CK-MM, CK-MB, CK-BB) kpɔ be wòakpe ɖe ŋuwò nànya lãmeka ƒomevi si gblẽ:

• CK-MM enzymes: Ne agbɔsɔsɔ siawo sɔ gbɔ la, ate ŋu afia be lãmekawo xɔ abi alo lãmekawo ƒe dɔléle, le kpɔɖeŋu me, nɔnɔme aɖe abe lãmekawo ƒe dɔmawɔmawɔ nyuie alo rhabdomyolysis ene.
• CK-MB ƒe dɔlékuiwutike:Ne agbɔsɔsɔ siawo sɔ gbɔ la, ate ŋu afia be dɔdzẽ le wò dzitodzito me, alo be dzidɔ le fu ɖem na wò alo nèxɔe nyitsɔ laa.
• CK-BB enzymes: Ne agbɔsɔsɔ siawo sɔ gbɔ la, ate ŋu afia be ʋusɔgbɔdɔ alo ahɔhɔ̃ xɔ abi le ŋuwò.

Susu bubu siwo tae creatine kinase (CK) ƒe agbɔsɔsɔ ate ŋu adzi ɖe edzi ɖo

Atikewɔwɔ me nɔnɔme aɖewo kple abi siwo medo ƒome kple wò lãmekawo tẽ o hã ate ŋu ana CK ƒe agbɔsɔsɔ nadzi ɖe edzi. Nusiwo gbɔ wòtso dometɔ aɖewoe nye esi:

• Dɔlékui siwo le lãmenugbagbeviwo me, abe lãkusidɔ, Addison ƒe dɔléle, alo Cushing ƒe dɔléle ene.
• Amekoko siwo wowɔna ɣeyiɣi didi.
• Alɔ̃madɔmadɔ.
• Dɔlékuiwo (dɔlékui, dɔlékui, fungi alo parasitic).
• Kadodo ƒe dɔlélewo, le kpɔɖeŋu me, lupus kple ƒunukpeƒetetedɔ.
• Celiac dɔléle.
• Ayiku ƒe dɔmawɔmawɔ nyuie.
• Asrã sesẽ si me ʋuʋudedi le.
• Ʋu ƒe sisi.
• Atike alo aɖi ɖesiaɖe si doa kplamatse lãmekawo ƒe ŋusẽ wɔwɔ alo ana ŋusẽ ƒe hiahiã nadzi ɖe edzi.
• Ne wole atikewo dom na ame.

Ðe wòle be matsi dzi ne nye creatine kinase (CK) ƒe agbɔsɔsɔ sɔ gbɔ wu alesi wòle dzɔdzɔmeea?

Ne wò CK dodokpɔ me tsonu ɖee fia be wò CK ƒe agbɔsɔsɔme sɔ gbɔ hã la, mefia kokoko be dɔléle aɖe le ŋuwò o. Wò CK ƒe agbɔsɔsɔ ate ŋu adzi ɖe edzi hena ɣeyiɣi aɖe le susu geɖe ta, abe kamedede, atike aɖewo nono, alo atikewo dodo ene. Ate ŋu adzɔ hã be nane gblẽ le dodokpɔa wɔɣi.

Ne wò ɖɔkta le nyametsotso wɔm le wò dɔwɔwɔ me tsonu ŋu la, abu nu geɖe ŋu, abe atike siwo zãm nèle fifia, wò agbenɔnɔ, kple wò dzesiwo ene. Agblɔ na wò nenye be ehiã be woadoe kpɔ ake.

Ne nya aɖe le asiwò ku ɖe wò dɔwɔwɔ me tsonu ŋu la, mègavɔ̃ be yeaƒo nu kple wò ɖɔkta o.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Zi geɖe la, lãmekawo ƒe vevesese kple gbɔdzɔgbɔdzɔ nyea ɣeyiɣi kpui aɖe ko. Gake ne lãmekawo ƒe kuxi siwo yia edzi le ŋuwò la , ƒo nu tso wò dzesiwo ŋu na wò ɖɔkta. Aɖe gbe be woawɔ CK dodokpɔ kple dodokpɔ bubuwo atsɔ adze agbagba adi nusi gbɔ wò dzesiawo tso.

Enye nusi sɔ be vɔvɔ̃ naɖo ŋuwò ne èkpɔ dodokpɔ me tsonu si mesɔ o. Gake ɖo ŋku edzi be CK ƒe agbɔsɔsɔ si sɔ gbɔ mefia kokoko be dɔléle sesẽ aɖe le ŋuwò eye nèhiã atikewɔwɔ o. Wò ɖɔkta agblɔ na wò nenye be ehiã be woadoe kpɔ geɖe wu be woakpɔ nusi gbɔ agbɔsɔsɔ si mesɔ o tso. Mègavɔ̃ be yeabia nya wò ɖɔkta o. Wole afima be yewoakpe ɖe ŋuwò.

Nusiwo dzi nàɖo ŋkui tso nyati sia me (Take-Home Message) .

Enyo, eyata míeƒo nu geɖe tso CK ŋu egbea, alo? Nu ʋɛ aɖewo siwo dzi wòle be woaɖo ŋkui kpuie lae nye esi:

• CK nye enzyme si ƒoa ƒu ɖe ʋua me ne nu gblẽ le lãmekawo, dzi, alo ahɔhɔ̃ ŋu.
• CK dodokpɔ dzidzea CK ƒe agbɔsɔsɔ le ʋua me. Ne ekɔ la, ate ŋu afia be lãmekawo gblẽ.
• Susu geɖe ate ŋu anɔ anyi siwo tae CK nadzi ɖe edzi ɖo. Ate ŋu atso nuwo abe kamedede, atike aɖewo, kple abixɔxɔ hã gbɔ.
• Màte ŋu anya dɔléle aɖe kple kakaɖedzi ne èlé ŋku ɖe wò CK ƒe agbɔsɔsɔ ŋu ko o. Wò ɖɔkta anɔ te ɖe wò dzesi bubuwo kple dodokpɔ bubuwo me tsonu dzi atso nya me.
• Ne nya aɖe le asiwò ku ɖe wò CK ƒe nyatakaka ŋu la, mègavɔ̃ be yeabia wò ɖɔkta o.

Eyata, mele mɔ kpɔm be nyatakaka sia aɖe vi na wò. Nɔ lãmesẽ me!

` Creatine Kinase, CK Dodokpɔ, Lãmetsi Vevesese, Lãmetsi Dɔléle, Enzymes, Ʋu Dodokpɔ, Lãmesẽ