Ðe wò mo vuvu zi ɖekaa? Ðe wò aɖe gbãa? Ðe wòate ŋu anye Melkersson-Rosenthal Dɔléle (MRS)a?

Èkpɔ, alo kpɔ wò mo ƒe akpa ɖeka vuvu kpata, nuyi si vuvu, mo ƒe akpa ɖeka ƒe ʋuʋu, alo wò aɖe ƒe gbagbã wɔnuku aɖe gɔ̃ hã kpɔa? Ðewohĩ esiawo menye nudzɔdzɔ dzro aɖe ko o. Woate ŋu anye nɔnɔme aɖe si mebɔ o si ŋu míele nu ƒom tsoe la ƒe dzesiwo.

Nukae nye Melkersson-Rosenthal Dɔléle?

Enyo, eyata mina míalé ŋku ɖe nusi Melkersson-Rosenthal Syndrome nye, alo MRS kpuie ŋu. Kpuie ko la, enye ahɔhɔ̃mekawo ƒe dɔléle si mebɔ kura o. Eyae nye be, míaƒe mo ƒe lãmekawo koŋue wògblẽa nu le. Nɔnɔme sia ƒe dzesi vevitɔwoe nye mo ƒe vuvu, aɖe ƒe gbagbã wɔnukuwo (abe do goglowo ene), kple mo ƒe lãmetutudɔ, si nye mo ƒe akpa ɖeka alo evea siaa ƒe dɔwɔwɔ ƒe gbegblẽ. Bu eŋu kpɔ, kasia, wohe nu ƒe dzogoe ɖe anyi eye màte ŋu ami ŋku nyuie o.

`MRS` nɔnɔme sia ateŋu anye nɔnɔme aɖe si ava le etsɔme ƒe dzesi ɣeaɖewoɣi, abe Crohn ƒe dɔléle (dɔgbowo ƒe dɔléle si nɔa anyi didi) alo sarcoidosis (dɔléle si nana ƒunukpeƒe suesuesue siwo vuvu le ŋutilã ƒe akpa vovovowo). Ðɔktawo yɔa nɔnɔme sia ɣeaɖewoɣi be ``Orofacial Granulomatosis`` . Enye nɔnɔme si naa ƒu suesuesue siwo le ƒuƒlu siwo woyɔna be granulomas, siwo kpena ɖe mo kple nu me vuvu ŋu.

Amekae ate ŋu atu `MRS` nɔnɔme sia ɖo? Aleke gbegbe wòbɔe?

Fifia ɖewohĩ èle eŋu bum be, "Amekae ate ŋu axɔ esia?" Le nyateƒe me la, nɔnɔme sia si woyɔna be `MRS` ateŋu adze egɔme le ƒe ɖesiaɖe me. Gake ebɔ ɖe sɔhɛwo me wu, zi geɖe le woƒe ƒe 20-awo ƒe gɔmedzedze, ne dzesiawo dze dzedze gɔme.

Gake ne míeƒo nu tso alesi wòbɔe ŋu la, MRS nye dɔléle si mebɔ kura o . Wogblɔ be ekpɔa ŋusẽ ɖe amewo ƒe alafa memamã sue aɖe ŋutɔ dzi, si ade 0.08%. Gake dzɔdzɔmeŋutinunyalawo xɔe se be esi dɔlélea ƒe dzesiwo sɔ kple dɔléle bubuwo ta la, ate ŋu adzɔ be ame geɖewo aganɔ anyi siwo ŋu womekpɔ dɔlélea le o. Esia fia be ate ŋu anye be ame geɖe siwo le fu kpem le nɔnɔme sia me wu xexlẽme sia. Eyata ne dzesi siawo tɔgbe le ŋuwò la, mègana ta le eŋu bubu be, "Esia dzɔna ɖe ame ʋɛ aɖewo ŋutɔ dzi, mɔ aɖeke meli si dzi mato axɔe o." Nu vevitɔ kekeakee nye be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo.

Nukae nye nusiwo gbɔ `MRS` tsona?

Enyo, azɔ mina míakpɔ nusi hea `MRS` nɔnɔme sia vɛ ɖa. Ne míagblɔe tututu la, dzɔdzɔmeŋutinunyalawo mete ŋu ke ɖe nusi tututu gbɔ wòtso ŋu haɖe o . Gake nu ʋɛ aɖewo li siwo wosusu be woawoe nana nɔnɔme sia dzɔna:

• Crohn ƒe dɔléle: Abe alesi megblɔe va yi ene la, dɔgboa ƒe dɔléle si nɔa anyi didie nye esia. Wokpɔe be amesiwo ŋu dɔléle sia le la le afɔku me be woaxɔ MRS.
• Domenyiŋusẽfianu: Esia fia be woate ŋu atsɔe tso dzidzime yi dzidzime. Ne nɔnɔme sia dze ame aɖe dzi le ƒomea me kpɔ la, ema hã ate ŋu anye susu aɖe si tae. Gake womeɖo kpe esia dzi haɖe o.
• Hypersensitivity reaction: Esia nye ne míaƒe ŋutilã ƒe dɔlélenutsiŋutete wɔa nu wògbɔa eme ɖe nane ŋu (si míeyɔna be ‘antigen’ alo ‘allergen’ - si fia be ate ŋu anye nane si hea nulɔdɔ vɛ). Ele abe nulɔdɔ ene, gake esesẽ vie wu.
• Sarcoidosis: Esia hã nye dɔléle si nana ƒuƒu suesuesuewo (granulomas) ƒoa ƒu ɖe ŋutilã ƒe akpa vovovowo. Wosusui hã be dɔléle sia do ƒome kple MRS.
• Dɔlékui alo dɔlékuiwo ƒe dɔléle: Nukpɔsusu aɖewo li be nɔnɔme sia ate ŋu adzɔ ɣeaɖewoɣi le dɔléle si dɔlékui alo dɔlékui aɖe he vɛ megbe.

Ðe `MRS` nye `(Autoimmune dɔléle)`?

Fifia ame aɖewo ate ŋu anɔ wo ɖokui biam be, "Ðe esia nye `(Autoimmune disease)'?" Eyae nye be, ɖe wònye nɔnɔme si me míaƒe ŋutilã ŋutɔ ƒe dɔlélenutsiŋutete dzea mía ŋutɔwo ƒe lãmenugbagbevi siwo le lãmesẽ me dzia? Le nyateƒe me la, womebua `MRS` be enye `(Autoimmune disease)' o.

Wobu esia be enye ahɔhɔ̃mekawo ƒe dɔléle . Ema fia be enye kuxi le ahɔhɔ̃ alo lãmekawo ŋu. Wogayɔnae be granulomatous disorder . Ema fia be enye dɔléle si nɔa anyi didi, si vuvu, si nye ƒunukpeƒetetedɔ (granuloma) si dzɔna le ŋutilã ƒe lãkusiwo me. See? Eyata medze ɖe "autoimmune" ƒe hatsotso me tẽ o.

Nukae nye `MRS` ƒe dzesiwo?

Enyo, eyata mina míalé ŋku ɖe `MRS` nɔnɔme sia ƒe dzesiwo ŋu azɔ, alo `(Orofacial Granulomatosis)` nɔnɔme si megblɔ va yi. Dzesi vevi etɔ̃e wokpɔna le esia me. Woyɔa esiawo be `dzesi etɔ̃ siwo wonya nyuie' .

1. Mo ƒe ʋuʋu: Esia nye nɔnɔme si me gbɔdzɔgbɔdzɔ alo lãmetutudɔ nɔa mo ƒe akpa ɖeka, ɣeaɖewoɣi le akpa eveawo. Ðewohĩ esia manɔ anyi le gɔmedzedzea me o, gake ate ŋu adze le emegbe. Ne dɔlélea le sesẽm ɖe edzi la, lãmetutudɔ sia ƒe ɣeyiɣi didi ate ŋu adzi ɖe edzi. Bu eŋu kpɔ, kasia màte ŋu aʋuʋu wò nu ƒe akpa ɖeka o, wò ŋkuwo tutu sesẽ na wò, alo wò nu ƒe dzogoe aɖe nado go ne èle tsi nom.

2. Mo ƒe ʋuʋu: Zi geɖe la, amesiwo ŋu MRS le la ƒe mo vuvu (Orofacial edema). Nuyi ƒe vuvu (Cheilitis granulomatosis) koŋue bɔ. Zi geɖe la, nuyi si le etame la vuvu hafi nuyi si le ete. Nuyiawo ate ŋu aƒu, agbã, abi, eye woate ŋu azu aŋutiɖiɖi gɔ̃ hã. Le ame aɖewo gome la, nuyiwo ate ŋu asesẽ abe kpe ene. Menye nuyiwo ɖeɖeko o, ke boŋ ŋgonu, ŋkume, kple ɣeaɖewoɣi ta gɔ̃ hã ate ŋu avuvu. Vuvu sia ate ŋu asẽ ɖe edzi eye wòanɔ anyi eteƒe nadidi ne dɔlélea gadze egɔme.

3. Aɖe si me ʋuʋudedi le:Esia nana be gbagbã goglo siwo le abe do ene la dzɔna le aɖea tame. Ðɔktawo yɔa esia hã be ``Scrotal tongue'' alo ``Lingua plicata''. Zi geɖe la, esia mevea ame o, gake ame aɖewo ate ŋu avuvu, avuvu, eye aɖe naxɔ dzo. Ate ŋu ana ame ƒe vivi nabu eye wòana ame naxɔ dɔlékuiwo le nu me hã.

Nu vevitɔe nye be menye amesiamee si nɔnɔme etɔ̃ siawo katã le o. Ðewohĩ nɔnɔme etɔ̃ siawo dometɔ ɖeka alo eve koe anɔ ame aɖewo si. Ðewohĩ ame etɔ̃awo katã anɔ ame bubuwo si.

Dzesi siawo menɔa anyi ɖaa o. Wova hedzona. Zi gbãtɔ la, ɖewohĩ gaƒoƒo ʋɛ aɖewo koe woanɔ anyi . Gake ne wotrɔ gbɔ emegbe la, woate ŋu asẽ wu eye woanɔ anyi eteƒe nadidi.

Dzesi bubuwo

Tsɔ kpe ɖe dzesi vevi siawo ŋu la, dzesi bubu geɖewo ate ŋu anɔ anyi:

• Taɖuame
• Taɖuame si nye taɖuame
• Towo ƒe ɖiɖi (tinnitus) alo to ƒe dɔmawɔmawɔ nyuie
• Ne dɔlélea nu sẽ eye wòhaya vɔ la, abi ate ŋu adze le mo ɣeaɖewoɣi .
• Nu mimi sesẽ
• Nukpɔkpɔ ƒe kuxiwo: Ŋku ƒe ƒuƒu, ŋku ƒe dzedzeme si me kɔ o, kple ŋku ƒe dɔdzẽ (uveitis).

Aleke wokpɔa MRS ƒe dɔléleae?

Fifia àte ŋu anɔ eŋu bum be, "Aleke mawɔ anya kple kakaɖedzi be `MRS` ye nye esia?" Le nyateƒe me la, `MRS` ƒe dɔlélea didi sesẽ vie. Elabena woate ŋu atɔtɔ eƒe dzesiwo kple nɔnɔme bubuwo. Le kpɔɖeŋu me, eƒe dzesiwo ateŋu asɔ kple `Allergic reactions` alo `Bell's palsy`, nɔnɔme bubu si nana mo ƒe lãme ʋuʋuna.

Zi geɖe la, ɖɔkta dea dzesi MRS to wò ŋutinya me léle kpɔ me ne dzesi etɔ̃ siwo ŋu meƒo nu tsoe va yi la dometɔ eve ya teti le ŋuwò. Ɣeaɖewoɣi la, be woaɖo kpe dɔlélea dzi eye woaɖe nɔnɔme bubuwo ɖa la, woate ŋu aɖe lãkusi sue aɖe tso wò nuyi me atsɔ adoe kpɔ (woaɖe ŋutilã ƒe lãmenugbagbeviwo ɖa). Esia adi be granulomas ƒe anyinɔnɔ hã.

Azɔ hã, ɖɔktaa ate ŋu aɖo wò ɖe eŋutinunyala bibi bubu geɖe gbɔ, elabena esia ate ŋu akpɔ ŋusẽ ɖe ɖoɖo geɖe dzi. Esiawo dometɔ aɖewoe nye:

• Nulɔdɔŋutinunyala
• Ŋutilãŋutinunyala
• Dɔgboŋutinunyala - Kpɔ nuwo abe Crohn ƒe dɔléle ene ɖa.
• Dɔlélenutsiŋutete ŋuti nunyala
• Ŋkudɔdala

Ðe atike aɖe li na `MRS`? Nukawoe nye atikewɔmɔnuawo?

Enyo, biabia gãtɔ si le ame geɖe si fifia enye, "Ðe atike blibo aɖe li na `MRS` nɔnɔme sia?" Nublanuitɔe la, womekpɔ atike si ŋu kakaɖedzi le na `MRS` haɖe o.

Ɣeaɖewoɣi la, dzesiawo nu yina atike aɖeke mawɔmawɔe, gake woate ŋu agava.

Eyata aleke nèwɔa nu ɖe ​​eŋu? Ne dzesiawo gadze ake eye wòɖea fu na ame la, atikewɔmɔnu vovovowo li siwo ate ŋu akpe ɖe ame ŋu be vevesese dzi naɖe akpɔtɔ, axe mɔ ɖe dɔlékuiwo xɔxɔ nu, eye wòana ame ƒe dzedzeme nanyo ɖe edzi. Woawoe nye:

• Dɔlékuiwutikewo: Ne dɔlékui aɖe le ame ŋu.
• Antihistamines: Ðe dzesi siwo le abe nulɔdɔ ene kple abi ƒe vuvu dzi kpɔtɔna.
• Corticosteroids: Esiawo nye atike sẽŋu siwo ɖea abi kple abi dzi kpɔtɔna. Woate ŋu ado wo abe atike siwo wodona ɖe teƒe si dɔdzẽa le tẽ ene, alo abe atikekuiwo ene.
• Dɔlélenutsiŋutete ƒe dɔlékuiwutikewo: Esiawo kpena ɖe ame ŋu be dɔdzẽ dzi ɖena kpɔtɔna to dɔlélenutsiŋutete ƒe dɔwɔwɔ dzi ɖuɖu vie me.
• Methotrexate: Esia hã nye atike si kpɔa dɔlélenutsiŋutete dzi eye wòɖea dɔdzẽ dzi kpɔtɔna.
• Atike siwo me steroid mele o siwo tsia dzodzodzoetsitsi nu (NSAIDs): Ðe vevesese kple abi dzi kpɔtɔna (e.g., Ibuprofen, Diclofenac).
• Amekoko: Woate ŋu awɔ amekoko ɣeaɖewoɣi be woaɖe nuyi siwo vuvu ŋutɔ ƒe vuvu dzi akpɔtɔ alo be woaɖe mo ƒe lãmekawo ƒe nyaƒoɖeamenu dzi akpɔtɔ. Ke hã, ƒã hafi wowɔa esia.
• TNF-alpha inhibitors: Esiawo hã nye atike tɔxɛ aɖe si kpena ɖe ame ŋu wòdzudzɔa dɔdzẽ. Zi geɖe la, wonaa wo ne atike bubuwo mewɔ dɔ o.

Wotrɔ asi le atikewɔwɔ siawo ŋu be woatsɔ aɖu dzesiwo dzi eye woaɖe vevesese dzi akpɔtɔ. Wò ɖɔkta akpɔ atike si anyo na wò wu.

Ðe woate ŋu axe mɔ ɖe `MRS` ƒe nɔnɔmea nua?

Ðe woate ŋu axe mɔ ɖe `MRS` ƒe nɔnɔme sia nua? Le nyateƒe me la, esi dzɔdzɔmeŋutinunyalawo mese nusi gbɔ esia tsona gɔme bliboe haɖe o ta la, mɔnu aɖeke meli si ŋu kpeɖodzi le si dzi woato axe mɔ ɖe enu o. Eyata ele be míaƒe susu nanɔ dzesiawo nyanya kaba kple atikewɔwɔ nyuitɔ didi ŋu.

Aleke `MRS` anɔ? Ðe wòahayaa?

Nukae etsɔme ahe vɛ na amesi ŋu MRS le? Esia toa vovo ŋutɔŋutɔ tso ame ɖeka gbɔ yi bubu gbɔ. Ame aɖewo ƒe dzesiwo nu mesẽna kura o, abe zi ɖeka le ƒe ʋɛ aɖewo ɖesiaɖe me ene, eye wodzona le wo ɖokui si. Le ame bubuwo gome la, dzesiawo ate ŋu adze enuenu, abe ŋkeke ʋɛ ɖesiaɖe ene, eye woate ŋu agblẽ ɖe edzi ɣesiaɣi.

Nɔnɔme sia ate ŋu anɔ anyi le eƒe agbemeŋkekewo katã me, eye vuvua ate ŋu anɔ anyi ɖaa. Gake dzɔdzɔmeŋutinunyalawo mesusui be dɔléle sia gblẽa nu le ame ƒe agbenɔƒe ŋu o. Ema fia be àte ŋu anɔ agbe si sɔ kplii, gake ele be nànɔ agbe kple dzesiawo. Eya ta susu me nɔnɔ hã le vevie ŋutɔ.

Nya siwo wòle be nàbia wò ɖɔkta

Ne Melkersson-Rosenthal Syndrome le ŋuwò, alo nèsusu be exɔe la, anyo be nàbia nya siawo wò ɖɔkta:

• Aleke nàwɔ agblɔe kple kakaɖedzi be Melkersson-Rosenthal Dɔlélee nye esia? Ðe mate ŋu anye nu bubu aɖe oa?
• Eŋutinunyala bibi bubu kawoe wòle be makpɔ? (e.g., ŋutigbalẽŋutinunyala, ahɔhɔ̃ŋutinunyala, kple bubuawo)
• Ne dzesiawo gadze ake la, ɣekaɣie wòle be madi atikewɔlawo ƒe aɖaŋuɖoɖo? Dzesi kawo ŋue wòle be matsi dzi ɖo vevie?
• Ðe wòle be woadom kpɔ be Crohn ƒe dɔléle alo sarcoidosis le ŋunyea?
• Nukae wòle be mawɔ be maxɔ dɔlékuiwo, avuvu tegbee, kple abi ƒe ƒoƒo nu?
• Ðe nèkafui be woado domenyiŋusẽfianu kpɔa? Nukae wòate ŋu agblɔ na wò?
• Ðe nènya kpekpeɖeŋunaha aɖewo siwo kpena ɖe amesiwo ŋu nɔnɔme siawo le ŋua? Ðe viɖe aɖewo anɔ eme ne meva wɔ ɖeka kpli woa?

Eyata nu vevi kawoe wòle be míatsɔ ayi aƒemee tso ŋutinya sia me?

Melkersson-Rosenthal Syndrome (MRS) nye dɔléle si mebɔ kura o si gblẽa nu le mo ƒe lãmekawo ŋu. Ne èkpɔ mo na wò kpata, mo vuvu, alo wò aɖe ƒe gbagbã wɔnuku aɖe la, ele be nàyi ɖɔkta gbɔ godoo.

Togbɔ be womekpɔ atike aɖeke koŋ na esia o hã la, atikewɔmɔnu nyui aɖewo li siwo dzi woato aɖu dzesiawo dzi, aɖe vevesese dzi akpɔtɔ, eye woaxe mɔ ɖe kuxiwo nu. Eyata mègatsi dzi o. Ne ède dzesii kaba eye nèdae nyuie la, àte ŋu anɔ agbe nyuie kple nɔnɔme sia. Menye wò ɖeka koe o, eye wò ɖɔktawo kple wò lɔlɔ̃tɔwo ate ŋu akpe ɖe ŋuwò.

` Melkersson-Rosenthal ƒe dɔléle, MRS, mo ƒe vuvu, mo ƒe lãmetutudɔ, aɖe si me ʋuʋu, ahɔhɔ̃mekawo ƒe dɔléle, orofacial granulomatosis